Jonathan C. Cohen
Active 1987–2024
- 105
- Papers
- 43,025
- Citations
- 90
- h-index
- 105
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine69.9%
- Biochemistry, Genetics and Molecular Biology24.5%
- Immunology and Microbiology1.4%
- Neuroscience0.8%
- Agricultural and Biological Sciences0.7%
- Nursing0.7%
- Other2%
Topics
- Liver Disease Diagnosis and Treatment12%
- Lipoproteins and Cardiovascular Health5.3%
- Diabetes, Cardiovascular Risks, and Lipoproteins4.8%
- Diet, Metabolism, and Disease4.2%
- Cholesterol and Lipid Metabolism3.9%
- Lipid metabolism and disorders3.3%
- Other66.5%
Coauthors
- Helen H. Hobbs85
- Julia Kozlitina10
- Liqing Yu10
- Viktoria Gusarova10
- Jay D. Horton9
- Jesper Gromada9
- Scott M. Grundy9
- Eric Boerwinkle8
- Fang Xu8
- Alexander Pertsemlidis7
- L Pennacchio7
- Andrew Murphy6
- Dieter Lütjohann6
- Yan Wang6
- Ēriks Šmagris6
- Anne Tybjærg‐Hansen5
- George D. Yancopoulos5
- Gloria Lena Vega5
- Klaus von Bergmann5
- Lisa M. Shihanian5
- Lisa N. Kinch5
- Ruth McPherson5
- Serena Banfi5
- Soumik BasuRay5
All papers
- Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
Authors: Stefano Romeo, Julia Kozlitina, Chao Xing, Alexander Pertsemlidis, David Cox, L Pennacchio, Eric Boerwinkle, Jonathan C. Cohen, Helen H. Hobbs - Nature Genetics 2008 cited by 3,385
- Sequence Variations in PCSK9, Low LDL, and Protection against Coronary Heart Disease
Authors: Jonathan C. Cohen, Eric Boerwinkle, Thomas H. Mosley, Helen H. Hobbs - New England Journal of Medicine 2006 cited by 3,205
- A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease
Authors: Noura S. Abul‐Husn, Xiping Cheng, Alexander Li, Yurong Xin, Claudia Schurmann, Panayiotis E. Stevis, Yashu Liu, Julia Kozlitina, Stefan Stender, G. Craig Wood, Ann Stepanchick, Matthew Still, Shane McCarthy, Colm O’Dushlaine, Jonathan S. Packer, Suganthi Balasubramanian, Nehal Gosalia, David Esopi, Sun Y. Kim, Semanti Mukherjee, Alexander Lopez, Erin D. Fuller, John S. Penn, Xin Chu, Jonathan Z. Luo, Uyenlinh L. Mirshahi, David J. Carey, Christopher D. Still, Michael D. Feldman, Aeron Small, Scott M. Damrauer, Daniel J. Rader, Brian Zambrowicz, William C. Olson, Andrew Murphy, Ingrid B. Borecki, Alan R. Shuldiner, Jeffrey G. Reid, John D. Overton, George D. Yancopoulos, Helen H. Hobbs, Jonathan C. Cohen, Omri Gottesman, Tanya M. Teslovich, Aris Baras, Tooraj Mirshahi, Jesper Gromada, Frederick E. Dewey - New England Journal of Medicine 2018 cited by 805
- Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease
Authors: Julia Kozlitina, Ēriks Šmagris, Stefan Stender, Børge G. Nordestgaard, Heather Zhou, Anne Tybjærg‐Hansen, Thomas Vogt, Helen H. Hobbs, Jonathan C. Cohen - Nature Genetics 2014 cited by 1,204
- Human Fatty Liver Disease: Old Questions and New Insights
Authors: Jonathan C. Cohen, Jay D. Horton, Helen H. Hobbs - Science 2011 cited by 2,088
- Prevalence of Hepatic Steatosis in An Urban Population in the United States: Impact of Ethnicity
Authors: Jeffrey D. Browning, Lidia S. Szczepaniak, Robert L. Dobbins, Pamela Nuremberg, Jay D. Horton, Jonathan C. Cohen, Scott M. Grundy, Helen H. Hobbs - Hepatology 2004 cited by 3,664
- Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis
Authors: Soumik BasuRay, Yang Wang, Ēriks Šmagris, Jonathan C. Cohen, Helen H. Hobbs - National Academy of Sciences, Proceedings of the National Academy of Sciences 2019 cited by 283
- Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci
Authors: Stefan Stender, Julia Kozlitina, Børge G. Nordestgaard, Anne Tybjærg‐Hansen, Helen H. Hobbs, Jonathan C. Cohen - Nature Genetics 2017 cited by 396
- Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9
Authors: Jonathan C. Cohen, Alexander Pertsemlidis, Ingrid K. Kotowski, Randall B. Graham, Christine Kim Garcia, Helen H. Hobbs - Nature Genetics 2005 cited by 1,387
- PNPLA3, CGI‐58, and Inhibition of Hepatic Triglyceride Hydrolysis in Mice
Authors: Yang Wang, Nora Kory, Soumik BasuRay, Jonathan C. Cohen, Helen H. Hobbs - Hepatology 2019 cited by 216
- The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation
Authors: Soumik BasuRay, Ēriks Šmagris, Jonathan C. Cohen, Helen H. Hobbs - Hepatology 2017 cited by 287
- Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance
Authors: Rene C. Adam, Ivory J. Mintah, Corey A. Alexa-Braun, Lisa M. Shihanian, Joseph S. Lee, Poulabi Banerjee, Sara Hamon, Hye In Kim, Jonathan C. Cohen, Helen H. Hobbs, Cristopher V. Van Hout, Jesper Gromada, Andrew Murphy, George D. Yancopoulos, Mark W. Sleeman, Viktoria Gusarova - Journal of Lipid Research 2020 cited by 202
- Exome Sequencing,ANGPTL3Mutations, and Familial Combined Hypolipidemia
Authors: Kiran Musunuru, James P. Pirruccello, Ron Do, Gina M. Peloso, Candace Guiducci, Carrie Sougnez, Kiran Garimella, Sheila Fisher, Justin Abreu, Andrew J. Barry, Tim Fennell, Eric Banks, Lauren Ambrogio, Kristian Cibulskis, Andrew Kernytsky, Elena González, Nicholas Rudzicz, James C. Engert, Mark A. DePristo, Mark J. Daly, Jonathan C. Cohen, Helen H. Hobbs, David Altshuler, Gustav Schonfeld, Stacey Gabriel, Pin Yue, Sekar Kathiresan - New England Journal of Medicine 2010 cited by 778
- A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis
Authors: Shaoqing He, Christopher McPhaul, John Li, Rita Garuti, Lisa N. Kinch, Nick V. Grishin, Jonathan C. Cohen, Helen H. Hobbs - Journal of Biological Chemistry 2009 cited by 600
- Hepatic TM6SF2 Is Required for Lipidation of VLDL in a Pre-Golgi Compartment in Mice and Rats
Authors: Fei Luo, Ēriks Šmagris, Sarah A. Martin, Gonçalo Vale, Jeffrey G. McDonald, Justin A. Fletcher, Shawn C. Burgess, Helen H. Hobbs, Jonathan C. Cohen - Cellular and Molecular Gastroenterology and Hepatology 2021 cited by 109
- Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis
Authors: Ēriks Šmagris, Soumik BasuRay, John Li, Yongcheng Huang, Ka‐Man Venus Lai, Jesper Gromada, Jonathan C. Cohen, Helen H. Hobbs - Hepatology 2014 cited by 374
- Binding of Proprotein Convertase Subtilisin/Kexin Type 9 to Epidermal Growth Factor-like Repeat A of Low Density Lipoprotein Receptor Decreases Receptor Recycling and Increases Degradation
Authors: Dawei Zhang, Thomas A. Lagace, Rita Garuti, Zhenze Zhao, Meghan McDonald, Jay D. Horton, Jonathan C. Cohen, Helen H. Hobbs - Journal of Biological Chemistry 2007 cited by 784
- Atypical angiopoietin-like protein that regulates ANGPTL3
Authors: Fabiana Quagliarini, Yan Wang, Julia Kozlitina, Nick V. Grishin, Rhonda Hyde, Eric Boerwinkle, David M. Valenzuela, Andrew Murphy, Jonathan C. Cohen, Helen H. Hobbs - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 cited by 456
- A feed-forward loop amplifies nutritional regulation of PNPLA3
Authors: Yongcheng Huang, Shaoqing He, John Li, Young‐Kyo Seo, Timothy F. Osborne, Jonathan C. Cohen, Helen H. Hobbs - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 382
- ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance
Authors: Jorge F. Haller, Ivory J. Mintah, Lisa M. Shihanian, Panayiotis E. Stevis, David G. Buckler, Corey A. Alexa-Braun, Sandra Kleiner, Serena Banfi, Jonathan C. Cohen, Helen H. Hobbs, George D. Yancopoulos, Andrew Murphy, Viktoria Gusarova, Jesper Gromada - Journal of Lipid Research 2017 cited by 206
- GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
Authors: Vidu Garg, Irfan S. Kathiriya, R. Bowling Barnes, Marie K. Schluterman, Isabelle N. King, Cheryl Butler, Caryn R. Rothrock, Reenu S. Eapen, Kayoko Hirayama‐Yamada, Kunitaka Joo, Rumiko Matsuoka, Jonathan C. Cohen, Deepak Srivastava - Nature 2003 cited by 1,242
- Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins
Authors: Ēriks Šmagris, Shenise Gilyard, Soumik BasuRay, Jonathan C. Cohen, Helen H. Hobbs - Journal of Biological Chemistry 2016 cited by 223
- PCSK9: a convertase that coordinates LDL catabolism
Authors: Jay D. Horton, Jonathan C. Cohen, Helen H. Hobbs - Journal of Lipid Research 2008 cited by 631
- Molecular Characterization of Loss-of-Function Mutations in PCSK9 and Identification of a Compound Heterozygote
Authors: Zhenze Zhao, Yetsa Tuakli-Wosornu, Thomas A. Lagace, Lisa N. Kinch, Nicholas V. Grishin, Jay D. Horton, Jonathan C. Cohen, Helen H. Hobbs - The American Journal of Human Genetics 2006 cited by 633
