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David T. Scadden

Active 1984–2025

Also published as
David T Scadden
210
Papers
65,695
Citations
126
h-index
207
i10-index

Citations

Citations per year for David T. Scadden1957: 1 citations1986: 1 citations1987: 6 citations1988: 4 citations1989: 11 citations1990: 29 citations1991: 32 citations1992: 22 citations1993: 30 citations1994: 22 citations1995: 46 citations1996: 55 citations1997: 47 citations1998: 47 citations1999: 51 citations2000: 81 citations2001: 123 citations2002: 173 citations2003: 193 citations2004: 294 citations2005: 394 citations2006: 476 citations2007: 645 citations2008: 710 citations2009: 693 citations2010: 736 citations2011: 818 citations2012: 747 citations2013: 781 citations2014: 824 citations2015: 838 citations2016: 751 citations2017: 812 citations2018: 751 citations2019: 2,091 citations2020: 2,227 citations2021: 2,258 citations2022: 1,684 citations2023: 1,194 citations2024: 1,714 citations2025: 841 citations2026: 29 citations1958–1985: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 8,540 citing papers, 33.6% of this breakdownChina: 3,021 citing papers, 11.9% of this breakdownGermany: 1,600 citing papers, 6.3% of this breakdownUnited Kingdom: 1,522 citing papers, 6% of this breakdownItaly: 1,075 citing papers, 4.2% of this breakdownJapan: 849 citing papers, 3.3% of this breakdownFrance: 828 citing papers, 3.3% of this breakdownCanada: 709 citing papers, 2.8% of this breakdownNetherlands: 593 citing papers, 2.3% of this breakdownAustralia: 589 citing papers, 2.3% of this breakdownSwitzerland: 558 citing papers, 2.2% of this breakdownSpain: 518 citing papers, 2% of this breakdown
0%33.6%Other 19.8%

Institutions

Fields

  • Medicine45%
  • Biochemistry, Genetics and Molecular Biology36%
  • Immunology and Microbiology9.7%
  • Engineering2.8%
  • Materials Science2.4%
  • Neuroscience2.2%
  • Other1.9%

Topics

  • Mesenchymal stem cell research3.5%
  • Hematopoietic Stem Cell Transplantation3.5%
  • Immune cells in cancer2.6%
  • Cancer Cells and Metastasis2.3%
  • Acute Myeloid Leukemia Research2.3%
  • Single-cell and spatial transcriptomics2%
  • Other83.8%

Coauthors

All papers

Open in search
  1. The bone marrow niche for haematopoietic stem cells

    Authors: Sean J. Morrison, David T. Scadden - Nature 2014 cited by 2,433

  2. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

    Authors: Simón Méndez‐Ferrer, Tatyana V. Michurina, Francesca Ferraro, Amin R. Mazloom, Ben D. MacArthur, Sérgio A. Lira, David T. Scadden, Avi Ma’ayan, Grigori Enikolopov, Paul S. Frenette - Nature 2010 cited by 3,371

  3. Bayesian approach to single-cell differential expression analysis

    Authors: Peter V. Kharchenko, Lev Silberstein, David T. Scadden - Nature Methods 2014 cited by 1,542

  4. A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia

    Authors: Ninib Baryawno, Dariusz Przybylski, Monika S. Kowalczyk, Youmna Kfoury, Nicolas Sévère, Karin Gustafsson, Konstantinos D. Kokkaliaris, François Mercier, Marcin Tabaka, Matan Hofree, Danielle Dionne, Ani Papazian, Dongjun Lee, Orr Ashenberg, Ayshwarya Subramanian, Eeshit Dhaval Vaishnav, Orit Rozenblatt–Rosen, Aviv Regev, David T. Scadden - Cell 2019 cited by 929

  5. Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses

    Authors: Taghreed Hirz, Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte Manouk Verhoeven, Alexander O. Subtelny, Dimitar V. Zlatev, Matthew W. Wszolek, Keyan Salari, Evan Murray, Fei Chen, Evan Z. Macosko, Chin‐Lee Wu, David T. Scadden, Douglas M. Dahl, Ninib Baryawno, Philip J. Saylor, Peter V. Kharchenko, David B. Sykes - Nature Communications 2023 cited by 247

  6. Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis

    Authors: Mélanie Demers, Daniela S. Krause, Daphne Schatzberg, Kimberly Martinod, Jaymie R. Voorhees, Tobias A. Fuchs, David T. Scadden, Denisa D. Wagner - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 cited by 873

  7. Direct measurement of local oxygen concentration in the bone marrow of live animals

    Authors: Joel A. Spencer, Francesca Ferraro, Emmanuel Roussakis, Alyssa Klein, Juwell W. Wu, Judith Runnels, Walid Zaher, Luke J. Mortensen, Clemens Alt, Raphaël Turcotte, Rushdia Z. Yusuf, Daniel Côté, Sergei A. Vinogradov, David T. Scadden, Charles P. Lin - Nature 2014 cited by 1,161

  8. Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment

    Authors: Youmna Kfoury, Ninib Baryawno, Nicolas Sévère, Shenglin Mei, Karin Gustafsson, Taghreed Hirz, Thomas Brouse, Elizabeth W. Scadden, Anna A. Igolkina, Konstantinos D. Kokkaliaris, Bryan D. Choi, Nikolas Barkas, Mark A. Randolph, John H. Shin, Philip J. Saylor, David T. Scadden, David B. Sykes, Peter V. Kharchenko - Cancer Cell 2021 cited by 275

  9. Osteoblasts remotely supply lung tumors with cancer-promoting SiglecF high neutrophils

    Authors: Camilla Engblom, Christina Pfirschke, Rapolas Žilionis, Janaina Da Silva Martins, Stijn A. Bos, Gabriel Courties, Steffen Rickelt, Nicolas Sévère, Ninib Baryawno, Julien Faget, Virginia Savova, David Zemmour, Jaclyn Kline, Marie Siwicki, Christopher Garris, Ferdinando Pucci, Hsin-Wei Liao, Yi-Jang Lin, Andita Newton, Omar Yaghi, Yoshiko Iwamoto, Benoit Tricot, Gregory R. Wojtkiewicz, Matthias Nahrendorf, Virna Cortez‐Retamozo, Etienne Meylan, Richard O. Hynes, Marie B. Demay, Allon M. Klein, Miriam A. Bredella, David T. Scadden, Ralph Weissleder, Mikaël J. Pittet - Science 2017 cited by 376

  10. Osteoblastic cells regulate the haematopoietic stem cell niche

    Authors: Laura M. Calvi, G. B. Adams, Kathryn Weibrecht, Jonathan M. Weber, David P. Olson, Melissa C. Knight, Roderick P. Martin, Ernestina Schipani, P. Divieti, F. Richard Bringhurst, Laurie A. Milner, Henry M. Kronenberg, David T. Scadden - Nature 2003 cited by 3,429

  11. C9orf72 suppresses systemic and neural inflammation induced by gut bacteria

    Authors: Aaron Burberry, Michael F. Wells, Francesco Limone, Alexander Benavides Couto, Kevin S. Smith, James Keaney, Gaëlle Gillet, Nick van Gastel, Jinyuan Wang, Olli Pietiläinen, Menglu Qian, Pierce Eggan, C. Ron Cantrell, Joanie Mok, Irena Kadiu, David T. Scadden, Kevin Eggan - Nature 2020 cited by 343

  12. Lipid availability determines fate of skeletal progenitor cells via SOX9

    Authors: Nick van Gastel, Steve Stegen, Guy Eelen, Sandra Schoors, Aurélie Carlier, Veerle W. Daniëls, Ninib Baryawno, Dariusz Przybylski, Maarten Depypere, Pieter‐Jan Stiers, Dennis Lambrechts, Riet Van Looveren, Sophie Torrekens, Azeem Sharda, Patrizia Agostinis, Diether Lambrechts, Frederik Maes, Johan Swinnen, Liesbet Geris, Hans Van Oosterwyck, Bernard Thienpont, Peter Carmeliet, David T. Scadden, Geert Carmeliet - Nature 2020 cited by 236

  13. Distinct bone marrow blood vessels differentially regulate haematopoiesis

    Authors: Tomer Itkin, Shiri Gur‐Cohen, Joel A. Spencer, Amir Schajnovitz, Saravana K. Ramasamy, Anjali P. Kusumbe, Guy Ledergor, Yookyung Jung, Idan Milo, Michael G. Poulos, Alexander Kalinkovich, Aya Ludin, Karin Golan, Eman Khatib, Anju Kumari, Órit Kollet, Guy Shakhar, Jason M. Butler, Shahin Rafii, Ralf H. Adams, David T. Scadden, Charles P. Lin, Tsvee Lapidot - Nature 2016 cited by 714

  14. Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

    Authors: Vanessa Frodermann, David Rohde, Gabriel Courties, Nicolas Sévère, Maximilian J. Schloss, Hajera Amatullah, Cameron S. McAlpine, Sebastian Cremer, Friedrich Felix Hoyer, Fei Ji, Ian D. van Koeverden, Fanny Hérisson, Lisa Honold, Gustavo Santos Masson, Shuang Zhang, Jana Grune, Yoshiko Iwamoto, Stephen Schmidt, Gregory R. Wojtkiewicz, I‐Hsiu Lee, Karin Gustafsson, Gerard Pasterkamp, Saskia C.A. de Jager, Ruslan I. Sadreyev, Jean MacFadyen, Peter Libby, Paul M. Ridker, David T. Scadden, Kamila Naxerova, Kate L. Jeffrey, Filip K. Świrski, Matthias Nahrendorf - Nature Medicine 2019 cited by 281

  15. Health Consequences of Thymus Removal in Adults

    Authors: Kameron Kooshesh, Brody H. Foy, David B. Sykes, Karin Gustafsson, David T. Scadden - New England Journal of Medicine 2023 cited by 164

  16. BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression

    Authors: Aldo M. Roccaro, Antonio Sacco, Patricia Maiso, Abdel Kareem Azab, Yu-Tzu Tai, Michaela R. Reagan, Feda Azab, Ludmila M. Flores, Federico Campigotto, Edie Weller, Kenneth C. Anderson, David T. Scadden, Irene M. Ghobrial - Journal of Clinical Investigation 2013 cited by 788

  17. Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia

    Authors: David B. Sykes, Youmna Kfoury, François Mercier, Mathias J. Wawer, Jason M. Law, Mark K. Haynes, Timothy A. Lewis, Amir Schajnovitz, Esha Jain, Dongjun Lee, Hanna Meyer, Kerry A. Pierce, Nicola Tolliday, Anna Waller, Steven Ferrara, Ashley Eheim, Detlef Stoeckigt, Katrina Maxcy, Julien Cobert, Jacqueline Bachand, Brian A. Szekely, Siddhartha Mukherjee, Larry A. Sklar, Joanne Kotz, Clary B. Clish, Ruslan I. Sadreyev, Paul A. Clemons, Andreas Janzer, Stuart L. Schreiber, David T. Scadden - Cell 2016 cited by 498

  18. The stem-cell niche as an entity of action

    Authors: David T. Scadden - Nature 2006 cited by 1,846

  19. In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche

    Authors: Joji Fujisaki, Juwell W. Wu, Alicia L. Carlson, Lev Silberstein, Prabhakar Putheti, Rafael A. Larocca, Wenda Gao, Toshiki Saito, Cristina Lo Celso, Hitoshi Tsuyuzaki, Tatsuyuki Sato, Daniel Côté, Megan Sykes, Terry B. Strom, David T. Scadden, Charles P. Lin - Nature 2011 cited by 557

  20. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer

    Authors: Christopher G. Willett, Yves Boucher, Emmanuelle di Tomaso, Dan G. Duda, Lance L. Munn, Ricky T. Tong, Daniel C. Chung, Dushyant V. Sahani, Sanjeeva P. Kalva, Sergey V. Kozin, Mari Mino, Kenneth S. Cohen, David T. Scadden, Alan C. Hartford, Alan J. Fischman, Jeffrey W. Clark, David P. Ryan, Andrew X. Zhu, Lawrence S. Blaszkowsky, Helen X Chen, Paul C. Shellito, Gregory Y. Lauwers, Rakesh K Jain - Nature Medicine 2004 cited by 1,957

  21. Mesenchymal Cell Contributions to the Stem Cell Niche

    Authors: Youmna Kfoury, David T. Scadden - Cell stem cell 2015 cited by 564

  22. Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration

    Authors: Dongsu Park, Joel A. Spencer, Bong Ihn Koh, Tatsuya Kobayashi, Joji Fujisaki, Thomas L. Clemens, Charles P. Lin, Henry M. Kronenberg, David T. Scadden - Cell stem cell 2012 cited by 631

  23. The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies

    Authors: Sven Christian, Claudia Merz, Laura Evans, Stefan Gradl, Henrik Seidel, Anders Friberg, Ashley Eheim, Pascale Lejeune, Krzysztof Brzezinka, Katja Zimmermann, Steven Ferrara, Hanna Meyer, Ralf Lesche, Detlef Stoeckigt, Marcus Bauser, Andrea Haegebarth, David B. Sykes, David T. Scadden, Julie-Aurore Losman, Andreas Janzer - Leukemia 2019 cited by 246

  24. Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation

    Authors: Angelo S. Mao, Berna Özkale, Nisarg J. Shah, Kyle H. Vining, Tiphaine Descombes, Liyuan Zhang, Christina M. Tringides, Sing Wan Wong, Jae‐Won Shin, David T. Scadden, David A. Weitz, David Mooney - National Academy of Sciences, Proceedings of the National Academy of Sciences 2019 cited by 174