Davide Ruggero
Active 1998–2025
- 68
- Papers
- 19,804
- Citations
- 54
- h-index
- 68
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology62.9%
- Medicine25.8%
- Immunology and Microbiology5.5%
- Neuroscience2.6%
- Computer Science0.7%
- Agricultural and Biological Sciences0.5%
- Other2%
Topics
- RNA modifications and cancer6.8%
- RNA and protein synthesis mechanisms4.6%
- RNA Research and Splicing4.2%
- PI3K/AKT/mTOR signaling in cancer3.9%
- Endoplasmic Reticulum Stress and Disease2.9%
- Cancer Cells and Metastasis2.6%
- Other75%
Coauthors
- Maria Barna9
- Alma L. Burlingame7
- Morgan Truitt7
- Andrew C. Hsieh6
- Duygu Kuzuoğlu‐Öztürk6
- Juan A. Osés-Prieto6
- Kevan M. Shokat6
- Pier Paolo Pandolfi6
- Craig R. Stumpf5
- Crystal S. Conn5
- Adrian Contreras4
- Constantinos Koumenis4
- Craig M. Forester4
- Cristian Bellodi4
- Feven Tameire4
- Hao G. Nguyen4
- Harrison Tom4
- John T. Cunningham4
- Lingru Xue4
- Nahum Sonenberg4
- Yichen Xu4
- Eduardo Magalhães Rego3
- Hani Goodarzi3
- Haojun Yang3
All papers
- VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
Authors: Rosandra N. Kaplan, Rebecca D. Riba, Stergios Zacharoulis, Anna H. Bramley, Loı̈c Vincent, Carla Costa, Daniel D. MacDonald, David Jin, Koji Shido, Scott Kerns, Zhenping Zhu, Daniel J. Hicklin, Yan Wu, Jeffrey L. Port, Nasser K. Altorki, Elisa Port, Davide Ruggero, Sergey V. Shmelkov, Kristian K. Jensen, Shahin Rafii, David Lyden - Nature 2005 cited by 3,260
- The translational landscape of mTOR signalling steers cancer initiation and metastasis
Authors: Andrew C. Hsieh, Yi Liu, Merritt P. Edlind, Nicholas T. Ingolia, Matthew R. Janes, Annie Sher, Evan Y. Shi, Craig R. Stumpf, Carly Christensen, Michael Bonham, Shunyou Wang, Pingda Ren, Michael Martin, Katti Jessen, Morris E. Feldman, Jonathan S. Weissman, Kevan M. Shokat, Christian Rommel, Davide Ruggero - Nature 2012 cited by 1,376
- Translation control of the immune checkpoint in cancer and its therapeutic targeting
Authors: Yichen Xu, Mauro Poggio, Hyun Yong Jin, Zhen Shi, Craig M. Forester, Ying Wang, Craig R. Stumpf, Lingru Xue, Emily N. Devericks, Lomon So, Hao G. Nguyen, Alice Griselin, John D. Gordan, Sarah E. Umetsu, Siegfried Reich, Stephen T. Worland, Saurabh Asthana, Maria Barna, Kevin R. Webster, John T. Cunningham, Davide Ruggero - Nature Medicine 2019 cited by 265
- Translational Control in Cancer
Authors: Nathaniel Robichaud, Nahum Sonenberg, Davide Ruggero, Robert J. Schneider - Cold Spring Harbor Perspectives in Biology 2018 cited by 303
- ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression
Authors: Feven Tameire, Ioannis I. Verginadis, Nektaria Maria Leli, Christine Polte, Crystal S. Conn, Rani Ojha, Carlo Salas Salinas, Frank Chinga, Alexandra M. Monroy, Weixuan Fu, Zhiping Wang, Andrew V. Kossenkov, Jiangbin Ye, Ravi K. Amaravadi, Zoya Ignatova, Serge Y. Fuchs, J. Alan Diehl, Davide Ruggero, Constantinos Koumenis - Nature Cell Biology 2019 cited by 302
- Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
Authors: Dana M. Gwinn, Alex G. Lee, Marcela Briones-Martín-del-Campo, Crystal S. Conn, David R. Simpson, Anna I. Scott, Anthony Le, Tina M. Cowan, Davide Ruggero, E. Alejandro Sweet‐Cordero - Cancer Cell 2018 cited by 228
- IRE1α Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2
Authors: John-Paul Upton, Likun Wang, Dan Han, Eric S. Wang, Noelle E. Huskey, Lionel Lim, Morgan Truitt, Michael T. McManus, Davide Ruggero, Andrei Goga, Feroz R. Papa, Scott A. Oakes - Science 2012 cited by 643
- ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance
Authors: Yichen Xu, Peiwei Huangyang, Ying Wang, Lingru Xue, Emily N. Devericks, Hao G. Nguyen, Xiuyan Yu, Juan A. Osés-Prieto, Alma L. Burlingame, Sohit Miglani, Hani Goodarzi, Davide Ruggero - Cell 2021 cited by 175
- rRNA Pseudouridylation Defects Affect Ribosomal Ligand Binding and Translational Fidelity from Yeast to Human Cells
Authors: Karen D. Jack, Cristian Bellodi, Dori M. Landry, Rachel O. Niederer, Arturas Meškauskas, Sharmishtha Musalgaonkar, Noam E. Kopmar, Olya Krasnykh, Alison M. Dean, Sunnie R. Thompson, Davide Ruggero, Jonathan D. Dinman - Molecular Cell 2011 cited by 333
- New frontiers in translational control of the cancer genome
Authors: Morgan Truitt, Davide Ruggero - Nature reviews. Cancer 2016 cited by 399
- Differential Requirements for eIF4E Dose in Normal Development and Cancer
Authors: Morgan Truitt, Crystal S. Conn, Zhen Shi, Xiaming Pang, Taku A. Tokuyasu, Alison Coady, Youngho Seo, Maria Barna, Davide Ruggero - Cell 2015 cited by 399
- Protein synthesis control in cancer: selectivity and therapeutic targeting
Authors: Joanna Kovalski, Duygu Kuzuoğlu‐Öztürk, Davide Ruggero - The EMBO Journal 2022 cited by 122
- Erratum: New frontiers in translational control of the cancer genome
Authors: Morgan Truitt, Davide Ruggero - Nature reviews. Cancer 2017 cited by 313
- ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth
Authors: Lori S. Hart, John T. Cunningham, Tatini Datta, Souvik Dey, Feven Tameire, Stacey L. Lehman, Bo Qiu, Haiyan Zhang, George J. Cerniglia, Meixia Bi, Yan Li, Yan Gao, Huayi Liu, Changhong Li, Amit Maity, Andrei Thomas‐Tikhonenko, Alexander E. Perl, Albert C. Koong, Serge Y. Fuchs, J. Alan Diehl, Ian G. Mills, Davide Ruggero, Constantinos Koumenis - Journal of Clinical Investigation 2012 cited by 446
- Targeting the eIF4F Translation Initiation Complex: A Critical Nexus for Cancer Development
Authors: Jerry Pelletier, Jeremy R. Graff, Davide Ruggero, Nahum Sonenberg - Cancer Research 2015 cited by 370
- Protein and Nucleotide Biosynthesis Are Coupled by a Single Rate-Limiting Enzyme, PRPS2, to Drive Cancer
Authors: John T. Cunningham, Melissa V. Moreno, Alessia Lodi, Sabrina M. Ronen, Davide Ruggero - Cell 2014 cited by 270
- Development of a stress response therapy targeting aggressive prostate cancer
Authors: Hao G. Nguyen, Crystal S. Conn, Yae Kye, Lingru Xue, Craig M. Forester, Janet E. Cowan, Andrew C. Hsieh, John T. Cunningham, Charles Truillet, Feven Tameire, Michael J. Evans, Christopher P. Evans, Joy C. Yang, Byron Hann, Constantinos Koumenis, Peter Walter, Peter R. Carroll, Davide Ruggero - Science Translational Medicine 2018 cited by 173
- Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
Authors: Morris E. Feldman, Beth Apsel, Aino Uotila, Robbie Loewith, Zachary A. Knight, Davide Ruggero, Kevan M. Shokat - PLoS Biology 2009 cited by 1,077
- A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS
Authors: Mary McMahon, Adrian Contreras, Mikael Holm, Tamayo Uechi, Craig M. Forester, Xiaming Pang, Cody B. Jackson, Meredith Calvert, Bin Chen, David A. Quigley, John M. Luk, R. K. Kelley, John D. Gordan, Ryan M. Gill, Scott C. Blanchard, Davide Ruggero - eLife 2019 cited by 142
- Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers
Authors: Michael Pourdehnad, Morgan Truitt, Imran Siddiqi, Gregory S. Ducker, Kevan M. Shokat, Davide Ruggero - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 296
- Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency
Authors: Maria Barna, Aya D. Pusic, Ornella Zollo, Maria Da Costa, Nadya Kondrashov, Eduardo Magalhães Rego, Pulivarthi H. Rao, Davide Ruggero - Nature 2008 cited by 427
- Autism-related deficits via dysregulated eIF4E-dependent translational control
Authors: Christos G. Gkogkas, Arkady Khoutorsky, Israeli Ran, Emmanouil Rampakakis, Tatiana Nevarko, D. Weatherill, Cristina Vasuta, Stephanie S. Yee, Morgan Truitt, Paul Dallaire, François Major, Paul Lasko, Davide Ruggero, Karim Nader, Jean‐Claude Lacaille, Nahum Sonenberg - Nature 2012 cited by 531
- Impaired Control of IRES-Mediated Translation in X-Linked Dyskeratosis Congenita
Authors: Andrew Yoon, Guang Peng, Yves Brandenburg, Ornella Zollo, Wei Xu, Eduardo Magalhães Rego, Davide Ruggero - Science 2006 cited by 420
- Evolutionarily divergent mTOR remodels translatome for tissue regeneration
Authors: Olena Zhulyn, Hannah D. Rosenblatt, Leila Shokat, Shizhong Dai, Duygu Kuzuoğlu‐Öztürk, Zijian Zhang, Davide Ruggero, Kevan M. Shokat, Maria Barna - Nature 2023 cited by 69
