Derek T. O’Hagan
Active 1989–2024
- Also published as
- Derek T. O'Hagan
- 120
- Papers
- 20,498
- Citations
- 87
- h-index
- 120
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Immunology and Microbiology31.9%
- Medicine26%
- Biochemistry, Genetics and Molecular Biology24.1%
- Pharmacology, Toxicology and Pharmaceutics9.1%
- Agricultural and Biological Sciences2.6%
- Materials Science2.3%
- Other4%
Topics
- Immunotherapy and Immune Responses12.5%
- RNA Interference and Gene Delivery9.4%
- SARS-CoV-2 and COVID-19 Research4.9%
- Advanced Drug Delivery Systems4.2%
- Immune Response and Inflammation4%
- Immune Cell Function and Interaction2.9%
- Other62.1%
Coauthors
- Manmohan Singh36
- Barbara C. Baudner13
- Rino Rappuoli11
- Ennio De Gregorio10
- Jeffrey B. Ulmer10
- Mildred Ugozzoli9
- S.S. Davis9
- Anja Seubert8
- Gary Ott8
- Prabhu S. Arunachalam8
- Jina Kazzaz7
- Luis A. Brito7
- Alexandra C. Walls6
- Andreas Wack6
- Brooke Fiala6
- Elizabeth Kepl6
- H. Jeffery6
- John Donnelly6
- John P. McGee6
- Lauren Carter6
- Marcos C. Miranda6
- Samuel Wrenn6
- Susan W. Barnett6
- Claire Sydeman5
All papers
- Emerging concepts in the science of vaccine adjuvants
Authors: Bali Pulendran, Prabhu S. Arunachalam, Derek T. O’Hagan - Nature Reviews Drug Discovery 2021 cited by 1,356
- Nonviral delivery of self-amplifying RNA vaccines
Authors: Andrew J. Geall, Ayush Verma, Gillis R. Otten, Christine A. Shaw, Armin Hekele, Kaustuv Banerjee, Yen Cu, Clayton W. Beard, Luis A. Brito, Thomas Krucker, Derek T. O’Hagan, Manmohan Singh, Peter W. Mason, Nicholas M. Valiante, Philip R. Dormitzer, Susan W. Barnett, Rino Rappuoli, Jeffrey B. Ulmer, Christian W. Mandl - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 cited by 667
- Adjuvanting a subunit COVID-19 vaccine to induce protective immunity
Authors: Prabhu S. Arunachalam, Alexandra C. Walls, Nadia Golden, Caroline Atyeo, Stephanie Fischinger, Chunfeng Li, Pyone P. Aye, Mary Jane Navarro, Lilin Lai, Venkata Viswanadh Edara, Katharina Röltgen, Kenneth A. Rogers, Lisa Shirreff, Douglas E. Ferrell, Samuel Wrenn, Deleah Pettie, John C. Kraft, Marcos C. Miranda, Elizabeth Kepl, Claire Sydeman, Natalie Brunette, Michael Murphy, Brooke Fiala, Lauren Carter, Alexander G. White, Meera Trisal, Ching‐Lin Hsieh, Kasi Russell‐Lodrigue, Christopher Monjure, Jason Dufour, Skye Spencer, Lara Doyle‐Meyers, Rudolph P. Bohm, Nicholas J. Maness, Chad J. Roy, Jessica A. Plante, Kenneth S. Plante, Alex Zhu, Matthew J. Gorman, Sally Shin, Xiaoying Shen, Jane Fontenot, Shakti Gupta, Derek T. O’Hagan, Robbert van der Most, Rino Rappuoli, Robert L. Coffman, David Novack, Jason S. McLellan, Shankar Subramaniam, David C. Montefiori, Scott D. Boyd, JoAnne L. Flynn, Galit Alter, François Villinger, Harry Kleanthous, Jay Rappaport, Mehul S. Suthar, Neil P. King, David Veesler, Bali Pulendran - Nature 2021 cited by 353
- A Cationic Nanoemulsion for the Delivery of Next-generation RNA Vaccines
Authors: Luis A. Brito, Michelle Y. Chan, Christine A. Shaw, Armin Hekele, Thomas Carsillo, Mary Schaefer, Jacob Archer, Anja Seubert, Gillis R. Otten, Clayton W. Beard, Antu Dey, Anders Lilja, Nicholas M. Valiante, Peter W. Mason, Christian W. Mandl, Susan W. Barnett, Philip R. Dormitzer, Jeffrey B. Ulmer, Manmohan Singh, Derek T. O’Hagan, Andrew J. Geall - Molecular Therapy 2014 cited by 333
- Lipid-Based Nanoparticles for Delivery of Vaccine Adjuvants and Antigens: Toward Multicomponent Vaccines
Authors: Despo Chatzikleanthous, Derek T. O’Hagan, Roberto Adamo - Molecular Pharmaceutics 2021 cited by 145
- Mechanism of action of mRNA-based vaccines
Authors: Carlo Iavarone, Derek T. O’Hagan, Dong Yü, Nicolas F. Delahaye, Jeffrey B. Ulmer - Expert Review of Vaccines 2017 cited by 247
- Optimizing the utilization of aluminum adjuvants in vaccines: you might just get what you want
Authors: Harm HogenEsch, Derek T. O’Hagan, Christopher B. Fox - npj Vaccines 2018 cited by 392
- Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines
Authors: Alexandra C. Walls, Marcos C. Miranda, Alexandra Schäfer, Minh N. Pham, Allison J. Greaney, Prabhu S. Arunachalam, Mary-Jane Navarro, M. Alejandra Tortorici, Kenneth A. Rogers, Megan A. O’Connor, Lisa Shirreff, Douglas E. Ferrell, John E. Bowen, Natalie Brunette, Elizabeth Kepl, Samantha K. Zepeda, Tyler N. Starr, Ching‐Lin Hsieh, Brooke Fiala, Samuel Wrenn, Deleah Pettie, Claire Sydeman, Kaitlin R. Sprouse, Max Johnson, Alyssa Blackstone, Rashmi Ravichandran, Cassandra Ogohara, Lauren Carter, Sasha W. Tilles, Rino Rappuoli, Sarah R. Leist, David R. Martinez, Matthew Clark, Roland Tisch, Derek T. O’Hagan, Robbert van der Most, Wesley C. Van Voorhis, Davide Corti, Jason S. McLellan, Harry Kleanthous, Timothy P. Sheahan, Kelly D. Smith, Deborah H. Fuller, François Villinger, Jesse D. Bloom, Bali Pulendran, Ralph S. Baric, Neil P. King, David Veesler - Cell 2021 cited by 192
- The role of nanoparticle format and route of administration on self-amplifying mRNA vaccine potency
Authors: Giulia Anderluzzi, Gustavo Lou, Stuart Woods, S. Schmidt, Simona Gallorini, Michela Brazzoli, Russell Johnson, Craig W. Roberts, Derek T. O’Hagan, Barbara C. Baudner, Yvonne Perrie - Journal of Controlled Release 2021 cited by 96
- The mechanism of action of MF59 – An innately attractive adjuvant formulation
Authors: Derek T. O’Hagan, Gary Ott, Ennio De Gregorio, Anja Seubert - Vaccine 2012 cited by 475
- Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles: The impact of cationic lipid selection
Authors: Gustavo Lou, Giulia Anderluzzi, S. Schmidt, Stuart Woods, Simona Gallorini, Michela Brazzoli, Fabiola Giusti, Ilaria Ferlenghi, Russell N. Johnson, Craig W. Roberts, Derek T. O’Hagan, Barbara C. Baudner, Yvonne Perrie - Journal of Controlled Release 2020 cited by 164
- Mannosylation of LNP Results in Improved Potency for Self-Amplifying RNA (SAM) Vaccines
Authors: Roshan Goswami, Despo Chatzikleanthous, Gustavo Lou, Fabiola Giusti, Alessandra Bonci, Marianna Taccone, Michela Brazzoli, Simona Gallorini, Ilaria Ferlenghi, Francesco Berti, Derek T. O’Hagan, Carlo Pergola, Barbara C. Baudner, Roberto Adamo - ACS Infectious Diseases 2019 cited by 112
- “World in motion” – emulsion adjuvants rising to meet the pandemic challenges
Authors: Derek T. O’Hagan, Robbert van der Most, Rushit N. Lodaya, Margherita Coccia, Giuseppe Lofano - npj Vaccines 2021 cited by 111
- Vaccine priming is restricted to draining lymph nodes and controlled by adjuvant-mediated antigen uptake
Authors: Frank Liang, Gustaf Lindgren, Kerrie J. Sandgren, Elizabeth A. Thompson, Joseph R. Francica, Anja Seubert, Ennio De Gregorio, Susan W. Barnett, Derek T. O’Hagan, Nancy J. Sullivan, Richard A. Koup, Robert A. Seder, Karin Loré - Science Translational Medicine 2017 cited by 209
- The history of MF59 ® adjuvant: a phoenix that arose from the ashes
Authors: Derek T. O’Hagan, Gary Ott, Gary Van Nest, Rino Rappuoli, Giuseppe Del Giudice - Expert Review of Vaccines 2012 cited by 311
- Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine
Authors: Yupeng Feng, Meng Yuan, John M. Powers, Mengyun Hu, Jennifer E. Munt, Prabhu S. Arunachalam, Sarah R. Leist, Lorenza Bellusci, JungHyun Kim, Kaitlin R. Sprouse, Lily E. Adams, Sumana Sundaramurthy, Xueyong Zhu, Lisa Shirreff, Michael L. Mallory, Trevor Scobey, Alberto Moreno, Derek T. O’Hagan, Harry Kleanthous, François Villinger, David Veesler, Neil P. King, Mehul S. Suthar, Surender Khurana, Ralph S. Baric, Ian A. Wilson, Bali Pulendran - Science Translational Medicine 2023 cited by 62
- Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
Authors: Fiona A. Sharp, Darren Ruane, Benjamin Claass, Emma M. Creagh, James Harris, Padma Malyala, Manomohan Singh, Derek T. O’Hagan, Virginie Pétrilli, Jürg Tschopp, Luke O'neill, Ed C. Lavelle - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 cited by 536
- The continued advance of vaccine adjuvants – ‘we can work it out’
Authors: Derek T. O’Hagan, Rushit N. Lodaya, Giuseppe Lofano - Seminars in Immunology 2020 cited by 107
- Rational design of small molecules as vaccine adjuvants
Authors: Tom Wu, Manmohan Singh, Andrew T. Miller, Ennio De Gregorio, Francesco Doro, Ugo D’Oro, David Skibinski, M. Lamine Mbow, Simone Bufali, Ann Herman, Alex Cortez, Yongkai Li, Bishnu P. Nayak, Elaine Tritto, Christophe Filippi, Gillis R. Otten, Luis A. Brito, Elisabetta Monaci, Chun Li, Susanna Aprea, Sara Valentini, Samuele Calabrό, Donatello Laera, Brunella Brunelli, Elena Caproni, Padma Malyala, Rekha G. Panchal, Travis K. Warren, Sina Bavari, Derek T. O’Hagan, M. Cooke, Nicholas M. Valiante - Science Translational Medicine 2014 cited by 176
- The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation, none of the individual components induce a comparable adjuvant effect
Authors: Samuele Calabrό, Elaine Tritto, Annamaria Pezzotti, Marianna Taccone, Alessandro Muzzi, Sylvie Bertholet, Ennio De Gregorio, Derek T. O’Hagan, Barbara C. Baudner, Anja Seubert - Vaccine 2013 cited by 215
- Molecular and cellular signatures of human vaccine adjuvants
Authors: Flaviana Mosca, Elaine Tritto, Alessandro Muzzi, Elisabetta Monaci, Fábio Bagnoli, Carlo Iavarone, Derek T. O’Hagan, Rino Rappuoli, Ennio De Gregorio - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 493
- Recent advances in the discovery and delivery of vaccine adjuvants
Authors: Derek T. O’Hagan, Nicholas M. Valiante - Nature Reviews Drug Discovery 2003 cited by 432
- Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes
Authors: Samuele Calabrό, Marco Tortoli, Barbara C. Baudner, Alessandra Pacitto, Mario Cortese, Derek T. O’Hagan, Ennio De Gregorio, Anja Seubert, Andreas Wack - Vaccine 2011 cited by 427
- Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus
Authors: Fábio Bagnoli, Maria Rita Fontana, Elisabetta Soldaini, Ravi P.N. Mishra, Luigi Fiaschi, Elena Cartocci, Vincenzo Nardi‐Dei, Paolo Ruggiero, Sarah Nosari, Maria Grazia De Falco, Giuseppe Lofano, Sara Marchi, Bruno Galletti, Paolo Mariotti, Marta Bacconi, Antonina Torre, Silvia Maccari, Maria Scarselli, C. Daniela Rinaudo, Naoko Inoshima, Silvana Savino, Elena Mori, Silvia Rossi-Paccani, Barbara C. Baudner, Michele Pallaoro, Erwin Swennen, Roberto Petracca, Cecilia Brettoni, Sabrina Liberatori, Nathalie Norais, Elisabetta Monaci, Juliane Bubeck Wardenburg, Olaf Schneewind, Derek T. O’Hagan, Nicholas M. Valiante, Giuliano Bensi, Sylvie Bertholet, Ennio De Gregorio, Rino Rappuoli, Guido Grandi - National Academy of Sciences, Proceedings of the National Academy of Sciences 2015 cited by 174
