Donald Küfe
Active 1972–2025
- Also published as
- Donald Kufe
- 246
- Papers
- 39,663
- Citations
- 124
- h-index
- 243
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology47.3%
- Medicine36%
- Immunology and Microbiology11.3%
- Neuroscience1.3%
- Engineering0.7%
- Chemistry0.6%
- Other2.8%
Topics
- Cell death mechanisms and regulation3.3%
- Immunotherapy and Immune Responses3.3%
- Glycosylation and Glycoproteins Research2.8%
- Cancer Immunotherapy and Biomarkers2%
- Cancer-related Molecular Pathways1.8%
- CAR-T cell therapy research1.8%
- Other85%
Coauthors
- Surender Kharbanda55
- Ralph R. Weichselbaum39
- Hasan Rajabi24
- Nami Yamashita22
- Rehan Ahmad22
- Atrayee Bhattacharya21
- Atsushi Fushimi20
- Pramod S. Pandey20
- Rakesh Datta18
- David Avigan17
- Deepak Raina16
- Mark D. Long16
- Ajit Bharti14
- Yoshihiro Morimoto14
- Jian Ren13
- Song Liu13
- David R. Spriggs12
- Tatsuaki Daimon12
- Dongshu Chen11
- Masayuki Hagiwara11
- Yongqing Li11
- Zhi-Min Yuan11
- Caining Jin10
- Dennis E. Hallahan10
All papers
- Mucins in cancer: function, prognosis and therapy
Authors: Donald Küfe - Nature reviews. Cancer 2009 cited by 1,405
- MUC1-C Induces PD-L1 and Immune Evasion in Triple-Negative Breast Cancer
Authors: Takahiro Maeda, Masayuki Hiraki, Caining Jin, Hasan Rajabi, Ashujit Tagde, Maroof Alam, Audrey Bouillez, Xiufeng Hu, Yozo Suzuki, Masaaki Miyo, Tsuyoshi Hata, Kunihiko Hinohara, Donald Küfe - Cancer Research 2017 cited by 274
- A Phase I First-in-Human Trial of Bardoxolone Methyl in Patients with Advanced Solid Tumors and Lymphomas
Authors: David S. Hong, Razelle Kurzrock, Jeffrey G. Supko, Xiaoying He, Aung Naing, Jennifer J. Wheler, Donald P. Lawrence, Joseph P. Eder, Colin J. Meyer, Deborah A. Ferguson, James W. Mier, Marina Konopleva, Sergej Konoplev, Michael Andreeff, Donald Küfe, Hillard Lazarus, Geoffrey I. Shapiro, Bruce J. Dezube - Clinical Cancer Research 2012 cited by 232
- Functional interactions of the cystine/glutamate antiporter, CD44v and MUC1-C oncoprotein in triple-negative breast cancer cells
Authors: Masanori Hasegawa, Hidekazu Takahashi, Hasan Rajabi, Maroof Alam, Yozo Suzuki, Yin Li, Ashujit Tagde, Takahiro Maeda, Masayuki Hiraki, Vikas P. Sukhatme, Donald Küfe - Oncotarget 2016 cited by 199
- MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer
Authors: Yota Yasumizu, Hasan Rajabi, Caining Jin, Tsuyoshi Hata, Sean P. Pitroda, Mark D. Long, Masayuki Hagiwara, Wei Li, Qiang Hu, Song Liu, Nami Yamashita, Atsushi Fushimi, Ling Kui, Mehmet Samur, Masaaki Yamamoto, Yan Zhang, Ning Zhang, Deli Hong, Takahiro Maeda, Takeo Kosaka, Kwok‐Kin Wong, Mototsugu Oya, Donald Küfe - Nature Communications 2020 cited by 194
- MUC1-mediated induction of myeloid-derived suppressor cells in patients with acute myeloid leukemia
Authors: Athalia R. Pyzer, Dina Stroopinsky, Hasan Rajabi, Abigail Washington, Ashujit Tagde, Maxwell Coll, Jacqueline Fung, Mary Paty Bryant, Leandra Cole, Kristen Palmer, Poorvi Somaiya, Rebecca Karp Leaf, Myrna Nahas, Arie Apel, Salvia Jain, Malgorzata McMasters, Lourdes Mendez, James D. Levine, Robin Joyce, Jon Arnason, Pier Paolo Pandolfi, Donald Küfe, Jacalyn Rosenblatt, David Avigan - Blood 2017 cited by 192
- MUC1-C integrates activation of the IFN-γ pathway with suppression of the tumor immune microenvironment in triple-negative breast cancer
Authors: Nami Yamashita, Mark D. Long, Atsushi Fushimi, Masaaki Yamamoto, Tsuyoshi Hata, Masayuki Hagiwara, Atrayee Bhattacharya, Qiang Hu, Kwok‐Kin Wong, Song Liu, Donald Küfe - Journal for ImmunoTherapy of Cancer 2021 cited by 81
- MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells
Authors: Masayuki Hagiwara, Atsushi Fushimi, Nami Yamashita, Atrayee Bhattacharya, Hasan Rajabi, Mark D. Long, Yota Yasumizu, Mototsugu Oya, Song Liu, Donald Küfe - Oncogene 2021 cited by 71
- MUC1-C Activates the BAF (mSWI/SNF) Complex in Prostate Cancer Stem Cells
Authors: Masayuki Hagiwara, Yota Yasumizu, Nami Yamashita, Hasan Rajabi, Atsushi Fushimi, Mark D. Long, Wei Li, Atrayee Bhattacharya, Rehan Ahmad, Mototsugu Oya, Song Liu, Donald Küfe - Cancer Research 2020 cited by 80
- MUC1-C Oncoprotein Functions as a Direct Activator of the Nuclear Factor-κB p65 Transcription Factor
Authors: Rehan Ahmad, Deepak Raina, Maya Datt Joshi, Takeshi Kawano, Jian Ren, Surender Kharbanda, Donald Küfe - Cancer Research 2009 cited by 190
- MUC1-C in chronic inflammation and carcinogenesis; emergence as a target for cancer treatment
Authors: Donald Küfe - Carcinogenesis 2020 cited by 92
- Individualized vaccination of AML patients in remission is associated with induction of antileukemia immunity and prolonged remissions
Authors: Jacalyn Rosenblatt, Richard M. Stone, Lynne Uhl, Donna Neuberg, Robin Joyce, James D. Levine, Jon Arnason, Malgorzata McMasters, Katarina Luptakova, Salvia Jain, Jeffrey I. Zwicker, Ayad Hamdan, Vassiliki A. Boussiotis, David P. Steensma, Daniel J. DeAngelo, Ilene Galinsky, Poorvi Somaiya Dutt, Emma Logan, Mary Paty Bryant, Dina Stroopinsky, Lillian Werner, Kristen Palmer, Max Coll, Abigail Washington, Leandra Cole, Donald Küfe, David Avigan - Science Translational Medicine 2016 cited by 164
- MUC1-C Is a Common Driver of Acquired Osimertinib Resistance in NSCLC
Authors: Naoki Haratake, Hiroki Ozawa, Yoshihiro Morimoto, Nami Yamashita, Tatsuaki Daimon, Atrayee Bhattacharya, Keyi Wang, Ayako Nakashoji, Hideko Isozaki, Mototsugu Shimokawa, Chie Kikutake, Mikita Suyama, Asato Hashinokuchi, Kazuki Takada, Tomoyoshi Takenaka, Tomoharu Yoshizumi, Tetsuya Mitsudomi, Aaron N. Hata, Donald Küfe - Journal of Thoracic Oncology 2023 cited by 45
- MUC1-C integrates type II interferon and chromatin remodeling pathways in immunosuppression of prostate cancer
Authors: Masayuki Hagiwara, Atsushi Fushimi, Atrayee Bhattacharya, Nami Yamashita, Yoshihiro Morimoto, Mototsugu Oya, Henry G. Withers, Qiang Hu, Tao Liu, Song Liu, Kwok K. Wong, Mark D. Long, Donald Kufe - OncoImmunology 2022 cited by 31
- Addiction of Cancer Stem Cells to MUC1-C in Triple-Negative Breast Cancer Progression
Authors: Nami Yamashita, Donald Küfe - International Journal of Molecular Sciences 2022 cited by 37
- MUC1-C is necessary for SHP2 activation and BRAF inhibitor resistance in BRAF(V600E) mutant colorectal cancer
Authors: Yoshihiro Morimoto, Nami Yamashita, Haruka Hirose, Atsushi Fushimi, Naoki Haratake, Tatsuaki Daimon, Atrayee Bhattacharya, Rehan Ahmad, Yozo Suzuki, Hidekazu Takahashi, Donald Küfe - Cancer Letters 2023 cited by 20
- Emergence of MUC1 in Mammals for Adaptation of Barrier Epithelia
Authors: Donald Küfe - Cancers 2022 cited by 35
- Multiparametric profiling of non–small-cell lung cancers reveals distinct immunophenotypes
Authors: Patrick H. Lizotte, Elena V. Ivanova, Mark M. Awad, Robert E. Jones, Lauren Keogh, Hongye Liu, Ruben Dries, Christina Almonte, Grit S. Herter-Sprie, Abigail Santos, Nora Feeney, Cloud P. Paweletz, Meghana Kulkarni, Adam J. Bass, Anil K. Rustgi, Guo‐Cheng Yuan, Donald Küfe, Pasi A. Jänne, Peter S. Hammerman, Lynette M. Sholl, F. Stephen Hodi, William G. Richards, Raphael Bueno, Jessie M. English, Mark Bittinger, Kwok‐Kin Wong - JCI Insight 2016 cited by 127
- MUC1-C Dictates PBRM1-Mediated Chronic Induction of Interferon Signaling, DNA Damage Resistance, and Immunosuppression in Triple-Negative Breast Cancer
Authors: Nami Yamashita, Yoshihiro Morimoto, Atsushi Fushimi, Rehan Ahmad, Atrayee Bhattacharya, Tatsuaki Daimon, Naoki Haratake, Yuka Inoue, Satoshi Ishikawa, Masaaki Yamamoto, Tsuyoshi Hata, Sayuri Akiyoshi, Qiang Hu, Tao Liu, Henry Withers, Song Liu, Geoffrey I. Shapiro, Tomoharu Yoshizumi, Mark D. Long, Donald Küfe - Molecular Cancer Research 2022 cited by 35
- MUC1-C is a master regulator of MICA/B NKG2D ligand and exosome secretion in human cancer cells
Authors: Yoshihiro Morimoto, Nami Yamashita, Tatsuaki Daimon, Haruka Hirose, Shizuka Yamano, Naoki Haratake, Satoshi Ishikawa, Atrayee Bhattacharya, Atsushi Fushimi, Rehan Ahmad, Hidekazu Takahashi, Olga Dashevsky, Constantine S. Mitsiades, Donald Küfe - Journal for ImmunoTherapy of Cancer 2023 cited by 25
- PD-1 Blockade by CT-011, Anti-PD-1 Antibody, Enhances Ex Vivo T-cell Responses to Autologous Dendritic Cell/Myeloma Fusion Vaccine
Authors: Jacalyn Rosenblatt, Brett Glotzbecker, Heidi Mills, Baldev Vasir, Dimitrios Tzachanis, James D. Levine, Robin Joyce, Kerry Wellenstein, Whitney Keefe, Michael Schickler, Rinat Rotem‐Yehudar, Donald Küfe, David Avigan - Journal of Immunotherapy 2011 cited by 282
- Triterpenoid CDDO-Me Blocks the NF-κB Pathway by Direct Inhibition of IKKβ on Cys-179
Authors: Rehan Ahmad, Deepak Raina, Colin J. Meyer, Surender Kharbanda, Donald Küfe - Journal of Biological Chemistry 2006 cited by 233
- MUC1 oncoprotein activates the IκB kinase β complex and constitutive NF-κB signalling
Authors: Rehan Ahmad, Deepak Raina, Vishal Trivedi, Jian Ren, Hasan Rajabi, Surender Kharbanda, Donald Küfe - Nature Cell Biology 2007 cited by 175
- MUC1-C Activates the NuRD Complex to Drive Dedifferentiation of Triple-Negative Breast Cancer Cells
Authors: Tsuyoshi Hata, Hasan Rajabi, Hidekazu Takahashi, Yota Yasumizu, Wei Li, Caining Jin, Mark D. Long, Qiang Hu, Song Liu, Atsushi Fushimi, Nami Yamashita, Ling Kui, Deli Hong, Masaaki Yamamoto, Masaaki Miyo, Masayuki Hiraki, Takahiro Maeda, Yozo Suzuki, Mehmet Samur, Donald Küfe - Cancer Research 2019 cited by 72
