litlas
Log inCreate account

Constantine S. Mitsiades

Active 1998–2025

114
Papers
29,389
Citations
87
h-index
112
i10-index

Citations

Citations per year for Constantine S. Mitsiades1986: 1 citations1992: 1 citations1993: 1 citations1996: 1 citations1999: 2 citations2000: 1 citations2001: 8 citations2002: 75 citations2003: 226 citations2004: 251 citations2005: 340 citations2006: 345 citations2007: 452 citations2008: 362 citations2009: 331 citations2010: 336 citations2011: 366 citations2012: 391 citations2013: 366 citations2014: 387 citations2015: 412 citations2016: 348 citations2017: 343 citations2018: 301 citations2019: 809 citations2020: 806 citations2021: 876 citations2022: 620 citations2023: 439 citations2024: 700 citations2025: 311 citations2026: 10 citations1987–1991: no citations, so these years are not shown1994–1995: no citations, so these years are not shown1997–1998: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 4,311 citing papers, 34.7% of this breakdownChina: 1,259 citing papers, 10.1% of this breakdownUnited Kingdom: 719 citing papers, 5.8% of this breakdownGermany: 692 citing papers, 5.6% of this breakdownItaly: 593 citing papers, 4.8% of this breakdownFrance: 437 citing papers, 3.5% of this breakdownSpain: 352 citing papers, 2.8% of this breakdownJapan: 345 citing papers, 2.8% of this breakdownCanada: 339 citing papers, 2.7% of this breakdownNetherlands: 293 citing papers, 2.4% of this breakdownAustralia: 282 citing papers, 2.3% of this breakdownSwitzerland: 258 citing papers, 2.1% of this breakdown
0%34.7%Other 20.4%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology49.3%
  • Medicine42.9%
  • Immunology and Microbiology4.2%
  • Chemistry0.8%
  • Engineering0.7%
  • Computer Science0.7%
  • Other1.4%

Topics

  • Protein Degradation and Inhibitors9.9%
  • Multiple Myeloma Research and Treatments8.8%
  • Ubiquitin and proteasome pathways6.9%
  • Histone Deacetylase Inhibitors Research3.4%
  • Peptidase Inhibition and Analysis2.8%
  • Cell death mechanisms and regulation1.9%
  • Other66.3%

Coauthors

All papers

Open in search
  1. The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins

    Authors: Gang Lu, Richard E. Middleton, Huahang Sun, MarkVic Naniong, Christopher J. Ott, Constantine S. Mitsiades, Kwok‐Kin Wong, James E. Bradner, William G. Kaelin - Science 2013 cited by 1,582

  2. BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

    Authors: Jake Delmore, Ghayas C. Issa, Madeleine E. Lemieux, Peter B. Rahl, Junwei Shi, Hannah M. Jacobs, Efstathios Kastritis, Timothy Gilpatrick, Ronald M. Paranal, Jun Qi, Marta Chesi, Anna C. Schinzel, Michael R. McKeown, Timothy P. Heffernan, Christopher R. Vakoc, P. Leif Bergsagel, Irene M. Ghobrial, Paul G. Richardson, Richard A. Young, William C. Hahn, Kenneth C. Anderson, Andrew L. Kung, James E. Bradner, Constantine S. Mitsiades - Cell 2011 cited by 2,874

  3. An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence

    Authors: Eugen Dhimolea, Ricardo De Matos Simoes, Dhvanir Kansara, Aziz Al’Khafaji, Juliette Bouyssou, Xiang Weng, Shruti Sharma, Joseline Raja, Pallavi Awate, Ryosuke Shirasaki, Huihui Tang, Brian Glassner, Zhiyi Liu, Dong Gao, Jordan Bryan, Samantha Bender, Jennifer A. Roth, Michal Scheffer, Rinath Jeselsohn, Nathanael S. Gray, Irene Georgakoudi, Francisca Vázquez, Aviad Tsherniak, Yu Chen, Alana L. Welm, Cihangir Duy, Ari Melnick, Boris Bartholdy, Myles Brown, Aedín C. Culhane, Constantine S. Mitsiades - Cancer Cell 2021 cited by 262

  4. Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

    Authors: Nicholas Kwiatkowski, Tinghu Zhang, Peter B. Rahl, Brian J. Abraham, Jessica Reddy, Scott B. Ficarro, Anahita Dastur, Arnaud Amzallag, Sridhar Ramaswamy, Bethany Tesar, Catherine E. Jenkins, Nancy M. Hannett, Douglas W. McMillin, Takaomi Sanda, Taebo Sim, Nam Doo Kim, Thomas Look, Constantine S. Mitsiades, Andrew P. Weng, Jennifer R. Brown, Cyril H. Benes, Jarrod A. Marto, Richard A. Young, Nathanael S. Gray - Nature 2014 cited by 908

  5. Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence

    Authors: Cihangir Duy, Meng Li, Matt Teater, Cem Meydan, Francine E. Garrett-Bakelman, Tak C. Lee, Christopher R. Chin, Ceyda Durmaz, Kimihito C. Kawabata, Eugen Dhimolea, Constantine S. Mitsiades, Hartmut Doehner, Richard J. D’Andrea, Michael W. Becker, Elisabeth Paietta, Christopher E. Mason, Martin Carroll, Ari Melnick - Cancer Discovery 2021 cited by 255

  6. Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins

    Authors: Ryosuke Shirasaki, Geoffrey M. Matthews, Sara Gandolfi, Ricardo De Matos Simoes, Dennis L. Buckley, Joseline Raja, Quinlan Sievers, Johanna B. Brüggenthies, Olga Dashevsky, Haley Poarch, Huihui Tang, Megan Bariteau, Michal Sheffer, Yiguo Hu, Sondra L. Downey-Kopyscinski, Paul J. Hengeveld, Brian Glassner, Eugen Dhimolea, Christopher J. Ott, Tinghu Zhang, Nicholas Kwiatkowski, Jacob P. Laubach, Robert Schlossman, Paul G. Richardson, Aedín C. Culhane, Richard W.J. Groen, Eric S. Fischer, Francisca Vázquez, Aviad Tsherniak, William C. Hahn, Joan Levy, Daniel Auclair, Jonathan D. Licht, Jonathan J. Keats, Lawrence Boise, Benjamin L. Ebert, James E. Bradner, Nathanael S. Gray, Constantine S. Mitsiades - Cell Reports 2021 cited by 115

  7. Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1

    Authors: Nathaniel W. Mabe, Min Huang, Guillermo Nicolás Dalton, Gabriela Alexe, Daniel A. Schaefer, Anna C. Geraghty, Amanda L. Robichaud, Amy Saur Conway, Delan Khalid, Marius Marc-Daniel Mader, Julia A. Belk, Kenneth N. Ross, Michal Sheffer, Miles H. Linde, Nghi Ly, Winnie Yao, Maria Caterina Rotiroti, Benjamin Smith, Marius Wernig, Carolyn R. Bertozzi, Michelle Monje, Constantine S. Mitsiades, Ravindra Majeti, Ansuman T. Satpathy, Kimberly Stegmaier, Robbie G. Majzner - Nature Cancer 2022 cited by 110

  8. Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy

    Authors: Tríona Ní Chonghaile, Kristopher A. Sarosiek, Thanh-Trang T. Vo, Jeremy Ryan, Anupama Tammareddi, Victoria Del Gaizo Moore, Jing Deng, Kenneth C. Anderson, Paul G. Richardson, Yu‐Tzu Tai, Constantine S. Mitsiades, Ursula A. Matulonis, Ronny Drapkin, Richard M. Stone, Daniel J. DeAngelo, David J. McConkey, Stephen E. Sallan, Lewis B. Silverman, Michelle S. Hirsch, Daniel R. Carrasco, Anthony Letai - Science 2011 cited by 595

  9. The role of tumour–stromal interactions in modifying drug response: challenges and opportunities

    Authors: Douglas W. McMillin, Joseph Negri, Constantine S. Mitsiades - Nature Reviews Drug Discovery 2013 cited by 465

  10. Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers

    Authors: Olli Dufva, Sara Gandolfi, Jani Huuhtanen, Olga Dashevsky, Hanna Duàn, Khalid Saeed, Jay Klievink, Petra Nygren, Jonas Bouhlal, Jenni Lahtela, Anna Näätänen, Bishwa Ghimire, Tiina Hannunen, Pekka Ellonen, Hanna Lähteenmäki, Pauliina Rumm, Jason Theodoropoulos, Essi Laajala, Jouni Härkönen, Petri Pölönen, Merja Heinäniemi, Maija Hollmén, Shizuka Yamano, Ryosuke Shirasaki, David A. Barbie, Jennifer A. Roth, Rizwan Romee, Michal Sheffer, Harri Lähdesmäki, Dean A. Lee, Ricardo De Matos Simoes, Matti Kankainen, Constantine S. Mitsiades, Satu Mustjoki - Immunity 2023 cited by 66

  11. Genome-scale screens identify factors regulating tumor cell responses to natural killer cells

    Authors: Michal Sheffer, Emily Lowry, Nicky A. Beelen, Minasri Borah, Suha Naffar-Abu Amara, Chris Mader, Jennifer A. Roth, Aviad Tsherniak, Samuel S. Freeman, Olga Dashevsky, Sara Gandolfi, Samantha Bender, Jordan Bryan, Cong Zhu, Li Wang, Ifrah Tariq, Govinda M. Kamath, Ricardo De Matos Simoes, Eugen Dhimolea, Channing Yu, Yiguo Hu, Olli Dufva, Marios Giannakis, Vasilis Syrgkanis, Ernest Fraenkel, Todd R. Golub, Rizwan Romee, Satu Mustjoki, Aedín C. Culhane, Lotte Wieten, Constantine S. Mitsiades - Nature Genetics 2021 cited by 98

  12. Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets

    Authors: Teru Hideshima, Constantine S. Mitsiades, Giovanni Tonon, Paul G. Richardson, Kenneth C. Anderson - Nature reviews. Cancer 2007 cited by 935

  13. Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias

    Authors: Ricardo De Matos Simoes, Ryosuke Shirasaki, Sondra L. Downey-Kopyscinski, Geoffrey M. Matthews, Benjamin G. Barwick, Vikas A. Gupta, Daphné Dupéré-Richer, Shizuka Yamano, Yiguo Hu, Michal Sheffer, Eugen Dhimolea, Olga Dashevsky, Sara Gandolfi, Kazuya Ishiguro, Robin M. Meyers, Jordan Bryan, Neekesh V. Dharia, Paul J. Hengeveld, Johanna B. Brüggenthies, Huihui Tang, Andrew J. Aguirre, Quinlan Sievers, Benjamin L. Ebert, Brian Glassner, Christopher J. Ott, James E. Bradner, Nicholas Kwiatkowski, Daniel Auclair, Joan Levy, Jonathan J. Keats, Richard W.J. Groen, Nathanael S. Gray, Aedín C. Culhane, James M. McFarland, Joshua M. Dempster, Jonathan D. Licht, Lawrence Boise, William C. Hahn, Francisca Vázquez, Aviad Tsherniak, Constantine S. Mitsiades - Nature Cancer 2023 cited by 40

  14. Functional Interaction of Plasmacytoid Dendritic Cells with Multiple Myeloma Cells: A Therapeutic Target

    Authors: Dharminder Chauhan, Ajita Singh, Mohan Brahmandam, Ruben D. Carrasco, Madhavi Bandi, Teru Hideshima, Giada Bianchi, Klaus Podar, Yu-Tzu Tai, Constantine S. Mitsiades, Noopur Raje, David L. Jaye, Shaji Kumar, Paul G. Richardson, Nikhil C. Munshi, Kenneth C. Anderson - Cancer Cell 2009 cited by 297

  15. Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS

    Authors: Laura Barreyro, Britta Will, Boris Bartholdy, Li Zhou, Tihomira I. Todorova, Robert Stanley, Susana Ben‐Neriah, Cristina Montagna, Samir Parekh, Andrea Pellagatti, Jacqueline Boultwood, Elisabeth Paietta, Rhett P. Ketterling, Larry D. Cripe, Hugo F. Fernández, Peter L. Greenberg, Martin S. Tallman, Christian Steidl, Constantine S. Mitsiades, Amit Verma, Ulrich Steidl - Blood 2012 cited by 203

  16. Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies

    Authors: Stephen Jun Fei Chong, Fen Zhu, Olga Dashevsky, Rin Mizuno, Jolin Xiao Hui Lai, Liam Hackett, Christine E. Ryan, Mary C. Collins, J. Bryan Iorgulescu, Romain Guièze, Johany Peñailillo, Ruben D. Carrasco, Yeonjoo Hwang, Denise P. Muñoz, Mehdi Bouhaddou, Yaw Chyn Lim, Catherine J. Wu, John N. Allan, Richard R. Furman, Boon Cher Goh, Shazib Pervaiz, Jean‐Philippe Coppé, Constantine S. Mitsiades, Matthew S. Davids - Journal of Clinical Investigation 2023 cited by 43

  17. Venetoclax sensitivity in multiple myeloma is associated with B-cell gene expression

    Authors: Vikas A. Gupta, Benjamin G. Barwick, Shannon M. Matulis, Ryosuke Shirasaki, David L. Jaye, Jonathan J. Keats, Benjamin Oberlton, Nisha S. Joseph, Craig C. Hofmeister, Leonard T. Heffner, Madhav V. Dhodapkar, Ajay K. Nooka, Sagar Lonial, Constantine S. Mitsiades, Jonathan L. Kaufman, Lawrence Boise - Blood 2021 cited by 81

  18. CDK7 controls E2F- and MYC-driven proliferative and metabolic vulnerabilities in multiple myeloma

    Authors: Yao Yao, Jessica Fong Ng, Woojun D. Park, Mehmet Samur, Eugenio Morelli, Jessica Encinas, Zuzana Chyra, Yan Xu, Sanika Derebail, Charles B. Epstein, Behnam Nabet, Marta Chesi, Nathanael S. Gray, Richard A. Young, Nicholas Kwiatkowski, Constantine S. Mitsiades, Kenneth C. Anderson, Charles Y. Lin, Nikhil C. Munshi, Mariateresa Fulciniti - Blood 2023 cited by 26

  19. Bortezomib induces canonical nuclear factor-κB activation in multiple myeloma cells

    Authors: Teru Hideshima, Hiroshi Ikeda, Dharminder Chauhan, Yutaka Okawa, Noopur Raje, Klaus Podar, Constantine S. Mitsiades, Nikhil C. Munshi, Paul G. Richardson, Ruben D. Carrasco, Kenneth C. Anderson - Blood 2009 cited by 371

  20. Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia

    Authors: Alejandro Gutiérrez, Pan Li, Richard W.J. Groen, Frédéric Baleydier, Alex Kentsis, Jason Marineau, Ruta Grebliunaite, Elena Kozakewich, Casie Reed, Françoise Pflumio, Sandrine Poglio, Benjamin Uzan, Paul A. Clemons, Lynn VerPlank, Frank An, Jason Burbank, Stephanie Norton, Nicola Tolliday, Hanno Steen, Andrew P. Weng, Huipin Yuan, James E. Bradner, Constantine S. Mitsiades, A. Thomas Look, Jon C. Aster - Journal of Clinical Investigation 2014 cited by 222

  21. Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib

    Authors: George Mulligan, Constantine S. Mitsiades, Barbara M. Bryant, Fenghuang Zhan, Wee Joo Chng, Steven Roels, Erik Koenig, Andrew Fergus, Yongsheng Huang, Paul G. Richardson, William L. Trepicchio, Annemiek Broyl, Pieter Sonneveld, John D. Shaughnessy, P. Leif Bergsagel, David P. Schenkein, Dixie‐Lee Esseltine, Anthony Boral, Kenneth C. Anderson - Blood 2006 cited by 421

  22. Immunomodulatory drug costimulates T cells via the B7-CD28 pathway

    Authors: Richard LeBlanc, Teru Hideshima, Laurence Catley, Reshma Shringarpure, Renate Burger, Nicholas Mitsiades, Constantine S. Mitsiades, P. Cheema, Dharminder Chauhan, Paul G. Richardson, Kenneth C. Anderson, Nikhil C. Munshi - Blood 2003 cited by 286

  23. Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma

    Authors: Simona Blotta, Jana Jakubı́ková, Teresa Calimeri, Aldo M. Roccaro, Nicola Amodio, Abdel Kareem Azab, Umberto Foresta, Constantine S. Mitsiades, Marco Rossi, Katia Todoerti, Stefano Molica, Fortunato Morabito, Antonino Neri, Piersandro Tagliaferri, Pierfrancesco Tassone, Kenneth C. Anderson, Nikhil C. Munshi - Blood 2012 cited by 138

  24. Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity

    Authors: Douglas W. McMillin, Jake Delmore, Ellen Weisberg, Joseph Negri, David C. Geer, Steffen Klippel, Nicholas Mitsiades, Robert Schlossman, Nikhil C. Munshi, Andrew L. Kung, James D. Griffin, Paul G. Richardson, Kenneth C. Anderson, Constantine S. Mitsiades - Nature Medicine 2010 cited by 315