A. Thomas Look
Active 1981–2024
- 213
- Papers
- 53,807
- Citations
- 124
- h-index
- 212
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine47.1%
- Biochemistry, Genetics and Molecular Biology39.1%
- Immunology and Microbiology8.5%
- Neuroscience1.9%
- Agricultural and Biological Sciences1%
- Chemistry0.4%
- Other2%
Topics
- Acute Myeloid Leukemia Research3.4%
- Acute Lymphoblastic Leukemia research3.4%
- Neuroblastoma Research and Treatments3.1%
- Epigenetics and DNA Methylation2.5%
- Cancer-related Molecular Pathways2.3%
- Immune Cell Function and Interaction1.9%
- Other83.4%
Coauthors
- John P. Kanki23
- Takaomi Sanda22
- Alejandro Gutiérrez20
- Donna Neuberg20
- Adolfo A. Ferrando15
- John M. Maris15
- Brian J. Abraham14
- Susan L. Cohn14
- Adam D. Durbin13
- Jeffery L. Kutok13
- Richard A. Young13
- Shuning He13
- David M. Langenau12
- Marc R. Mansour12
- Mark W. Zimmerman12
- Wendy B. London11
- Leonard I. Zon10
- DL Williams9
- Garrett M. Brodeur9
- Jennifer O’Neil9
- Jon C. Aster9
- Lewis B. Silverman9
- Rani E. George8
- Robert C. Seeger8
All papers
- A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
Authors: Philipp Niethammer, Clemens Grabher, A. Thomas Look, Timothy J. Mitchison - Nature 2009 cited by 1,551
- An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
Authors: Marc R. Mansour, Brian J. Abraham, Lars Anders, Alla Berezovskaya, Alejandro Gutiérrez, Adam D. Durbin, Julia Etchin, Lee N. Lawton, Stephen E. Sallan, Lewis B. Silverman, Mignon L. Loh, Stephen P. Hunger, Takaomi Sanda, Richard A. Young, A. Thomas Look - Science 2014 cited by 829
- EP300 Selectively Controls the Enhancer Landscape of MYCN -Amplified Neuroblastoma
Authors: Adam D. Durbin, Tingjian Wang, Virangika K. Wimalasena, Mark W. Zimmerman, Deyao Li, Neekesh V. Dharia, Luca Mariani, Noha A.M. Shendy, Stephanie Nance, Anand G. Patel, Ying Shao, Maya Mundada, Lily Maxham, Paul M.C. Park, Logan H. Sigua, Ken Morita, Amy Saur Conway, Amanda L. Robichaud, Antonio R. Pérez‐Atayde, Melissa J. Bikowitz, Taylor R. Quinn, Olaf Wiest, John Easton, E. Schönbrunn, Martha L. Bulyk, Brian J. Abraham, Kimberly Stegmaier, A. Thomas Look, Jun Qi - Cancer Discovery 2021 cited by 163
- Human aminopeptidase N is a receptor for human coronavirus 229E
Authors: Curtis Yeager, Richard A. Ashmun, Richard K. Williams, C B Cardellichio, Linda H. Shapiro, A. Thomas Look, Kathryn V. Holmes - Nature 1992 cited by 971
- Fusion of a Kinase Gene, ALK , to a Nucleolar Protein Gene, NPM , in Non-Hodgkin's Lymphoma
Authors: Stephan W. Morris, Mark N. Kirstein, Marcus B. Valentine, K. Dittmer, David N. Shapiro, David L. Saltman, A. Thomas Look - Science 1994 cited by 2,412
- Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
Authors: Andrew P. Weng, Adolfo A. Ferrando, Woojoong Lee, John P. Morris, Lewis B. Silverman, Cheryll Sanchez-Irizarry, Stephen C. Blacklow, A. Thomas Look, Jon C. Aster - Science 2004 cited by 2,732
- Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry
Authors: Adam D. Durbin, Mark W. Zimmerman, Neekesh V. Dharia, Brian J. Abraham, Amanda Balboni Iniguez, Nina Weichert‐Leahey, Shuning He, John M. Krill-Burger, David E. Root, Francisca Vázquez, Aviad Tsherniak, William C. Hahn, Todd R. Golub, Richard A. Young, A. Thomas Look, Kimberly Stegmaier - Nature Genetics 2018 cited by 302
- Resolution of inflammation by retrograde chemotaxis of neutrophils in transgenic zebrafish
Authors: Jonathan R. Mathias, Benjamin J. Perrin, Tingxi Liu, John P. Kanki, A. Thomas Look, Anna Huttenlocher - Journal of Leukocyte Biology 2006 cited by 527
- MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification
Authors: Mark W. Zimmerman, Yu Liu, Shuning He, Adam D. Durbin, Brian J. Abraham, John Easton, Ying Shao, Beisi Xu, Shizhen Zhu, Xiaoling Zhang, Zhaodong Li, Nina Weichert‐Leahey, Richard A. Young, Jinghui Zhang, A. Thomas Look - Cancer Discovery 2017 cited by 237
- Acute lymphoblastic leukaemia
Authors: Ching‐Hon Pui, Leslie L. Robison, A. Thomas Look - The Lancet 2008 cited by 1,551
- Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
Authors: Adolfo A. Ferrando, Donna Neuberg, Jane Staunton, Mignon L. Loh, Christine Huard, Susana C. Raimondi, Fred G. Behm, Ching‐Hon Pui, James R. Downing, D. Gary Gilliland, Eric S. Lander, Todd R. Golub, A. Thomas Look - Cancer Cell 2002 cited by 1,122
- NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
Authors: Teresa Palomero, Wei Keat Lim, Duncan T. Odom, Maria Luisa Sulis, Pedro J. Real, Adam A. Margolin, Kelly Barnes, Jennifer O’Neil, Donna Neuberg, Andrew P. Weng, Jon C. Aster, François Sigaux, Jean Soulier, A. Thomas Look, Richard A. Young, Andrea Califano, Adolfo A. Ferrando - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 cited by 822
- Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo
Authors: Shintaro Kamizono, Gordon S. Duncan, Markus G. Seidel, Akira Morimoto, Koichi Hamada, Gerard C. Grosveld, Koichi Akashi, Evan Lind, Jillian Haight, Pamela S. Ohashi, A. Thomas Look, Tak W. Mak - The Journal of Experimental Medicine 2009 cited by 329
- Activating mutations in ALK provide a therapeutic target in neuroblastoma
Authors: Rani E. George, Takaomi Sanda, Megan Hanna, Stefan Fröhling, William Luther, Jianming Zhang, Yebin Ahn, Wenjun Zhou, Wendy B. London, Patrick McGrady, Liquan Xue, Sergey Zozulya, V. Gregor, Thomas R. Webb, Nathanael S. Gray, D. Gary Gilliland, Lisa Diller, Heidi Greulich, Stephan W. Morris, Matthew Meyerson, A. Thomas Look - Nature 2008 cited by 899
- Evidence for an Age Cutoff Greater Than 365 Days for Neuroblastoma Risk Group Stratification in the Children's Oncology Group
Authors: Wendy B. London, R P Castleberry, Katherine K. Matthay, A. Thomas Look, Robert C. Seeger, Hiroyuki Shimada, Paul S. Thorner, G M Brodeur, John M. Maris, C. Patrick Reynolds, Susan L. Cohn - Journal of Clinical Oncology 2005 cited by 587
- Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T Cell Acute Lymphoblastic Leukemia
Authors: Takaomi Sanda, Lee N. Lawton, M. Inmaculada Barrasa, Zi Peng Fan, Holger Kohlhammer, Alejandro Gutiérrez, Wenxue Ma, Jessica Tatarek, Yebin Ahn, Michelle A. Kelliher, Catriona H.M. Jamieson, Louis M. Staudt, Richard A. Young, A. Thomas Look - Cancer Cell 2012 cited by 341
- Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma
Authors: Nicole Anderson, Xiaodan Qin, Jennifer M. Finan, Andrew Lam, Jacob Athoe, Rindert Missiaen, Nicolas Skuli, Annie Kennedy, Amandeep S. Saini, Ting Tao, Shizhen Zhu, Itzhak Nissim, A. Thomas Look, Guoliang Qing, M. Celeste Simon, Hui Feng - Cancer Research 2021 cited by 68
- The Use of Zebrafish to Understand Immunity
Authors: Nikolaus S. Trede, David M. Langenau, David Traver, A. Thomas Look, Leonard I. Zon - Immunity 2004 cited by 609
- In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish
Authors: David M. Langenau, Adolfo A. Ferrando, David Traver, Jeffery L. Kutok, John‐Paul D. Hezel, John P. Kanki, Leonard I. Zon, A. Thomas Look, Nikolaus S. Trede - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 cited by 445
- Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism
Authors: Derek A. Oldridge, Andrew Wood, Nina Weichert‐Leahey, Ian Crimmins, Robyn T. Sussman, Cynthia Winter, Lee McDaniel, Maura Diamond, Lori S. Hart, Shizhen Zhu, Adam D. Durbin, Brian J. Abraham, Lars Anders, Lifeng Tian, Shile Zhang, Jun S. Wei, Javed Khan, Kelli Bramlett, Nazneen Rahman, Mario Capasso, Achille Iolascon, Daniela S. Gerhard, Jaime M. Guidry Auvil, Richard A. Young, Håkon Håkonarson, Sharon J. Diskin, A. Thomas Look, John M. Maris - Nature 2015 cited by 303
- ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression
Authors: Hui Shi, Ting Tao, Brian J. Abraham, Adam D. Durbin, Mark W. Zimmerman, Cigall Kadoch, A. Thomas Look - Science Advances 2020 cited by 93
- tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors
Authors: Stéphane Berghmans, Ryan D. Murphey, Erno Wienholds, Donna Neuberg, Jeffery L. Kutok, Christopher D.�M. Fletcher, John P. Morris, Ting Xi Liu, Stefan Schulte‐Merker, John P. Kanki, Ronald H.A. Plasterk, Leonard I. Zon, A. Thomas Look - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 cited by 617
- ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry
Authors: Lu Wang, Tze King Tan, Adam D. Durbin, Mark W. Zimmerman, Brian J. Abraham, Shi Hao Tan, Phuong Cao Thi Ngoc, Nina Weichert‐Leahey, Koshi Akahane, Lee N. Lawton, Jo Lynne Rokita, John M. Maris, Richard A. Young, A. Thomas Look, Takaomi Sanda - Nature Communications 2019 cited by 99
- FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors
Authors: Jennifer O’Neil, Jonathan Grim, Peter R. Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James C.H. Hardwick, Markus Welcker, Jules P.P. Meijerink, Rob Pieters, Giulio Draetta, Rosalie C. Sears, Bruce E. Clurman, A. Thomas Look - The Journal of Experimental Medicine 2007 cited by 662
