Stephen C. Blacklow
Active 1988–2025
- 100
- Papers
- 20,236
- Citations
- 74
- h-index
- 99
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology50.3%
- Medicine33%
- Immunology and Microbiology9.4%
- Neuroscience1.7%
- Agricultural and Biological Sciences1.1%
- Nursing0.9%
- Other3.6%
Topics
- Developmental Biology and Gene Regulation4.8%
- Epigenetics and DNA Methylation2.9%
- Immune Cell Function and Interaction2.1%
- Cell Adhesion Molecules Research2%
- Cancer-related gene regulation1.9%
- Acute Lymphoblastic Leukemia research1.8%
- Other84.5%
Coauthors
- Jon C. Aster43
- Warren S. Pear22
- T.C.M. Seegar9
- Julia M. Rogers8
- Kelly L. Arnett8
- Andrew C. Kruse7
- Hongfang Wang7
- Wendy R. Gordon7
- Emily D. Egan6
- Lanwei Xu6
- Andrew P. Weng5
- Cheryll Sanchez-Irizarry5
- Gavin Histen5
- Jarrod A. Marto5
- Olga Shestova5
- Yunsun Nam5
- B Bernstein4
- Colin H. Lipper4
- David Sprinzak4
- Hyesung Jeon4
- Katherine J. Susa4
- Mark Y. Chiang4
- Michael J. Eck4
- Natalia Beglova4
All papers
- The Varied Roles of Notch in Cancer
Authors: Jon C. Aster, Warren S. Pear, Stephen C. Blacklow - Annual Review of Pathology Mechanisms of Disease 2016 cited by 730
- Biophysics of Notch Signaling
Authors: David Sprinzak, Stephen C. Blacklow - Annual Review of Biophysics 2021 cited by 225
- Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
Authors: Andrew P. Weng, Adolfo A. Ferrando, Woojoong Lee, John P. Morris, Lewis B. Silverman, Cheryll Sanchez-Irizarry, Stephen C. Blacklow, A. Thomas Look, Jon C. Aster - Science 2004 cited by 2,732
- Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch
Authors: Wendy R. Gordon, Brandon Zimmerman, Li He, Laura J. Miles, Jiuhong Huang, Kittichoat Tiyanont, Debbie G. McArthur, Jon C. Aster, Norbert Perrimon, Joseph J. Loparo, Stephen C. Blacklow - Developmental Cell 2015 cited by 385
- Development of a covalent inhibitor of gut bacterial bile salt hydrolases
Authors: Arijit A. Adhikari, T.C.M. Seegar, Scott B. Ficarro, Megan D. McCurry, Deepti Ramachandran, Lina Yao, Snehal N. Chaudhari, Sula Ndousse-Fetter, Alexander S. Banks, Jarrod A. Marto, Stephen C. Blacklow, A. Sloan Devlin - Nature Chemical Biology 2020 cited by 116
- Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket
Authors: Brandon Zimmerman, Brendan Kelly, Brian J. McMillan, T.C.M. Seegar, Ron O. Dror, Andrew C. Kruse, Stephen C. Blacklow - Cell 2016 cited by 305
- STRUCTURE AND PHYSIOLOGIC FUNCTION OF THE LOW-DENSITY LIPOPROTEIN RECEPTOR
Authors: Hyesung Jeon, Stephen C. Blacklow - Annual Review of Biochemistry 2005 cited by 387
- c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
Authors: Andrew P. Weng, John M. Millholland, Yumi Yashiro–Ohtani, Marie-Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G. Rodríguez, Hong Sai, John W. Tobias, Yue‐Ming Li, Michael S. Wolfe, Cathy Shachaf, Dean W. Felsher, Stephen C. Blacklow, Warren S. Pear, Jon C. Aster - Genes & Development 2006 cited by 885
- Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition
Authors: Jonathan R. LaRochelle, Michelle Fodor, Vidyasiri Vemulapalli, Morvarid Mohseni, Ping Wang, Travis Stams, Matthew J. LaMarche, Rajiv Chopra, Michael Acker, Stephen C. Blacklow - Nature Communications 2018 cited by 171
- Design of biologically active binary protein 2D materials
Authors: Ariel J. Ben‐Sasson, Joseph L. Watson, William Sheffler, Matthew C. Johnson, Alice Bittleston, Logeshwaran Somasundaram, Justin Decarreau, Fang Jiao, Jiajun Chen, Ioanna Mela, Andrew A. Drabek, Sanchez M. Jarrett, Stephen C. Blacklow, Clemens F. Kaminski, Greg L. Hura, James J. De Yoreo, Justin M. Kollman, Hannele Ruohola‐Baker, Emmanuel Derivery, David Baker - Nature 2021 cited by 146
- Pharmacological disruption of the Notch transcription factor complex
Authors: Rajwinder Lehal, Jelena Zarić, Michele Vigolo, Charlotte Urech, Viktoras Frismantas, Nadine Zangger, Linlin Cao, Adeline Berger, Irene Chicote, Sylvain Loubéry, Sung Hee Choi, Ute Koch, Stephen C. Blacklow, Héctor G. Pálmer, Beat Bornhäuser, Marcos González‐Gaitán, Yvan Arsenijévic, Vincent Zoete, Jon C. Aster, Jean‐Pierre Bourquin, Freddy Radtke - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 cited by 108
- Tetraspanins: structure, dynamics, and principles of partner-protein recognition
Authors: Katherine J. Susa, Andrew C. Kruse, Stephen C. Blacklow - Trends in Cell Biology 2023 cited by 79
- Structural Basis for Cooperativity in Recruitment of MAML Coactivators to Notch Transcription Complexes
Authors: Yunsun Nam, Piotr Sliz, Luyan Song, Jon C. Aster, Stephen C. Blacklow - Cell 2006 cited by 462
- Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81
Authors: Katherine J. Susa, Shaun Rawson, Andrew C. Kruse, Stephen C. Blacklow - Science 2021 cited by 78
- Direct inhibition of the NOTCH transcription factor complex
Authors: Raymond E. Moellering, Melanie Cornejo, Tina Davis, Cristina Del Bianco, Jon C. Aster, Stephen C. Blacklow, Andrew L. Kung, D. Gary Gilliland, Gregory L. Verdine, James E. Bradner - Nature 2009 cited by 755
- Dual Allosteric Inhibition of SHP2 Phosphatase
Authors: Michelle Fodor, Edmund V. Price, Ping Wang, Hengyu Lu, Andreea Argintaru, Zhouliang Chen, Meir Glick, Huai‐Xiang Hao, Mitsunori Kato, Robert Koenig, Jonathan R. LaRochelle, Gang Liu, Eric McNeill, Dyuti Majumdar, Gisele Nishiguchi, Lawrence Perez, Grégory Paris, Christopher M. Quinn, Timothy M. Ramsey, Martin Sendzik, Michael D. Shultz, Sarah Williams, Travis Stams, Stephen C. Blacklow, Michael Acker, Matthew J. LaMarche - ACS Chemical Biology 2018 cited by 130
- Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques
Authors: Jelena Petrovic, Yeqiao Zhou, Maria Fasolino, Naomi Goldman, Gregory W. Schwartz, Maxwell R. Mumbach, Son C. Nguyen, Kelly Rome, Yogev Sela, Zachary Zapataro, Stephen C. Blacklow, Michael J. Kruhlak, Junwei Shi, Jon C. Aster, Eric F. Joyce, Shawn C. Little, Golnaz Vahedi, Warren S. Pear, Robert B. Faryabi - Molecular Cell 2019 cited by 115
- A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking
Authors: Katherine J. Susa, T.C.M. Seegar, Stephen C. Blacklow, Andrew C. Kruse - eLife 2020 cited by 66
- Structural basis for membrane-proximal proteolysis of substrates by ADAM10
Authors: Colin H. Lipper, Emily D. Egan, Khal-Hentz Gabriel, Stephen C. Blacklow - Cell 2023 cited by 50
- Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma
Authors: Nicholas J. Wang, Zachary Sanborn, Kelly L. Arnett, Laura J. Bayston, Wilson Liao, Charlotte M. Proby, Irene M. Leigh, Eric A. Collisson, Patricia B. Gordon, Lakshmi R. Jakkula, Sally D. Pennypacker, Yong Zou, Mimansa Sharma, Jeffrey P. North, Swapna S. Vemula, Theodora M. Mauro, Isaac Neuhaus, Philip E. LeBoit, Joe S. Hur, Kyunghee Park, Nam Huh, Pui–Yan Kwok, Sarah T. Arron, Pierre P. Massion, A. Bale, David Haussler, James E. Cleaver, Joe W. Gray, Paul T. Spellman, Andrew P. South, Jon C. Aster, Stephen C. Blacklow, Raymond J. Cho - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 470
- A Zinc Clasp Structure Tethers Lck to T Cell Coreceptors CD4 and CD8
Authors: Peter W. Kim, Zhenyu Sun, Stephen C. Blacklow, Gerhard Wagner, Michael J. Eck - Science 2003 cited by 273
- NOTCH1–RBPJ complexes drive target gene expression through dynamic interactions with superenhancers
Authors: Hongfang Wang, Chongzhi Zang, Len Taing, Kelly L. Arnett, Yinling Joey Wong, Warren S. Pear, Stephen C. Blacklow, X. Shirley Liu, Jon C. Aster - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 266
- Structural Basis for Substrate Selectivity of the E3 Ligase COP1
Authors: Sacha Uljon, Xiang Xu, Izabela Durzynska, Sarah Stein, Guillaume Adelmant, Jarrod A. Marto, Warren S. Pear, Stephen C. Blacklow - Structure 2016 cited by 105
- Structural basis for autoinhibition of Notch
Authors: Wendy R. Gordon, Didem Vardar‐Ulu, Gavin Histen, Cheryll Sanchez-Irizarry, Jon C. Aster, Stephen C. Blacklow - Nature Structural & Molecular Biology 2007 cited by 376
