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Michael S. Wolfe

Active 1987–2025

107
Papers
25,283
Citations
77
h-index
104
i10-index

Citations

Citations per year for Michael S. Wolfe1979: 1 citations1988: 1 citations1989: 1 citations1990: 3 citations1991: 2 citations1992: 4 citations1993: 3 citations1994: 3 citations1995: 3 citations1996: 4 citations1997: 3 citations1998: 6 citations1999: 72 citations2000: 239 citations2001: 267 citations2002: 403 citations2003: 497 citations2004: 478 citations2005: 415 citations2006: 485 citations2007: 433 citations2008: 534 citations2009: 557 citations2010: 486 citations2011: 410 citations2012: 382 citations2013: 347 citations2014: 297 citations2015: 260 citations2016: 245 citations2017: 229 citations2018: 176 citations2019: 534 citations2020: 642 citations2021: 426 citations2022: 370 citations2023: 288 citations2024: 358 citations2025: 138 citations2026: 10 citations1980–1987: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,402 citing papers, 35.2% of this breakdownUnited Kingdom: 679 citing papers, 7% of this breakdownGermany: 673 citing papers, 7% of this breakdownChina: 585 citing papers, 6.1% of this breakdownJapan: 417 citing papers, 4.3% of this breakdownItaly: 371 citing papers, 3.8% of this breakdownCanada: 320 citing papers, 3.3% of this breakdownFrance: 259 citing papers, 2.7% of this breakdownBelgium: 233 citing papers, 2.4% of this breakdownIndia: 227 citing papers, 2.3% of this breakdownAustralia: 221 citing papers, 2.3% of this breakdownSweden: 220 citing papers, 2.3% of this breakdown
0%35.2%Other 21.3%

Institutions

Fields

  • Medicine60.9%
  • Biochemistry, Genetics and Molecular Biology26.1%
  • Neuroscience6.3%
  • Immunology and Microbiology2%
  • Computer Science1.1%
  • Chemistry0.8%
  • Other2.8%

Topics

  • Alzheimer's disease research and treatments18.5%
  • Cholinesterase and Neurodegenerative Diseases5.4%
  • Computational Drug Discovery Methods4.9%
  • Neuroscience and Neuropharmacology Research2.6%
  • Neuroinflammation and Neurodegeneration Mechanisms2.5%
  • Developmental Biology and Gene Regulation2.4%
  • Other63.7%

Coauthors

All papers

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  1. Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

    Authors: Dominic M. Walsh, Igor Klyubin, Julia V. Fadeeva, William K. Cullen, Roger Anwyl, Michael S. Wolfe, Michael J. Rowan, Dennis J. Selkoe - Nature 2002 cited by 4,294

  2. A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

    Authors: Bart De Strooper, Wim Annaert, Philippe Cupers, Paul Säftig, Katleen Craessaerts, Jeff S. Mumm, Eric H. Schroeter, Vincent Schrijvers, Michael S. Wolfe, William J. Ray, Alison Goate, Raphael Kopan - Nature 1999 cited by 2,108

  3. Presenilins and -Secretase: Structure, Function, and Role in Alzheimer Disease

    Authors: Bart De Strooper, Takeshi Iwatsubo, Michael S. Wolfe - Cold Spring Harbor Perspectives in Medicine 2011 cited by 462

  4. Tumor Necrosis Factor-α, Interleukin-1β, and Interferon-γ Stimulate γ-Secretase-mediated Cleavage of Amyloid Precursor Protein through a JNK-dependent MAPK Pathway

    Authors: Yung-Feng Liao, Bo‐Jeng Wang, Hui-Ting Cheng, Lan-Hsin Kuo, Michael S. Wolfe - Journal of Biological Chemistry 2004 cited by 387

  5. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity

    Authors: Michael S. Wolfe, Weiming Xia, Beth L. Ostaszewski, Thekla S. Diehl, W. Taylor Kimberly, Dennis J. Selkoe - Nature 1999 cited by 1,929

  6. The surface of articular cartilage contains a progenitor cell population

    Authors: Gary P. Dowthwaite, Joanna Bishop, Samantha Redman, Ilyas M. Khan, Paul Rooney, Darrell J. R. Evans, Laura Haughton, Zubeyde Bayram-Weston, Sam Boyer, B.M. Thomson, Michael S. Wolfe, Charles W. Archer - Journal of Cell Science 2004 cited by 908

  7. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

    Authors: Andrew P. Weng, John M. Millholland, Yumi Yashiro–Ohtani, Marie-Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G. Rodríguez, Hong Sai, John W. Tobias, Yue‐Ming Li, Michael S. Wolfe, Cathy Shachaf, Dean W. Felsher, Stephen C. Blacklow, Warren S. Pear, Jon C. Aster - Genes & Development 2006 cited by 885

  8. Structure and Function of the γ-Secretase Complex

    Authors: Michael S. Wolfe - Biochemistry 2019 cited by 119

  9. The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase

    Authors: David M. Bolduc, Daniel R. Montagna, Matthew Seghers, Michael S. Wolfe, Dennis J. Selkoe - eLife 2016 cited by 150

  10. The Role of Tau in Neurodegenerative Diseases and Its Potential as a Therapeutic Target

    Authors: Michael S. Wolfe - Scientifica 2012 cited by 98

  11. Identification of the Aβ37/42 peptide ratio in CSF as an improved Aβ biomarker for Alzheimer's disease

    Authors: Lei Liu, Bianca M. Lauro, Amy He, Hyo Lee, Sanjay Bhattarai, Michael S. Wolfe, David A. Bennett, Celeste M. Karch, Tracy L. Young‐Pearse, Dominantly Inherited Alzheimer Network (DIAN), Dennis J. Selkoe - Alzheimer s & Dementia 2022 cited by 53

  12. γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

    Authors: W. Taylor Kimberly, Matthew J. LaVoie, Beth L. Ostaszewski, Wenjuan Ye, Michael S. Wolfe, Dennis J. Selkoe - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 758

  13. Effects of presenilin-1 familial Alzheimer’s disease mutations on γ-secretase activation for cleavage of amyloid precursor protein

    Authors: N. Hung, Sujan Devkota, Apurba Bhattarai, Michael S. Wolfe, Yinglong Miao - Communications Biology 2023 cited by 27

  14. Familial Alzheimer’s disease mutations in amyloid protein precursor alter proteolysis by γ-secretase to increase amyloid β-peptides of ≥45 residues

    Authors: Sujan Devkota, Todd D. Williams, Michael S. Wolfe - Journal of Biological Chemistry 2021 cited by 70

  15. Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes

    Authors: Sujan Devkota, Rui Zhou, Vaishnavi Nagarajan, Masato Maesako, N. Hung, Arshad Ali Noorani, Caitlin Overmeyer, Sanjay Bhattarai, Justin T. Douglas, Anita Saraf, Yinglong Miao, Brian D. Ackley, Yigong Shi, Michael S. Wolfe - Cell Reports 2024 cited by 38

  16. Stabilization of the Tau Exon 10 Stem Loop Alters Pre-mRNA Splicing

    Authors: Christine P. Donahue, Christina Muratore, Jane Y. Wu, Kenneth S. Kosik, Michael S. Wolfe - Journal of Biological Chemistry 2006 cited by 107

  17. A G‐Rich element forms a G‐quadruplex and regulates BACE1 mRNA alternative splicing

    Authors: Jean‐François Fisette, Daniel R. Montagna, Mihaela‐Rita Mihailescu, Michael S. Wolfe - Journal of Neurochemistry 2012 cited by 104

  18. Mechanisms of γ-Secretase Activation and Substrate Processing

    Authors: Apurba Bhattarai, Sujan Devkota, Sanjay Bhattarai, Michael S. Wolfe, Yinglong Miao - ACS Central Science 2020 cited by 45

  19. A Portrait of Alzheimer Secretases-New Features and Familiar Faces

    Authors: William P. Esler, Michael S. Wolfe - Science 2001 cited by 494

  20. Hydrophilic loop 1 of Presenilin-1 and the APP GxxxG transmembrane motif regulate γ-secretase function in generating Alzheimer-causing Aβ peptides

    Authors: Lei Liu, Bianca M. Lauro, Michael S. Wolfe, Dennis J. Selkoe - Journal of Biological Chemistry 2021 cited by 45

  21. Notch mediates TGFα-induced changes in epithelial differentiation during pancreatic tumorigenesis

    Authors: Yoshiharu Miyamoto, Anirban Maitra, Bidyut Ghosh, Ulrich Zechner, Pedram Argani, Christine A. Iacobuzio–Donahue, Virote Sriuranpong, Tatsuya Iso, Ingrid M. Meszoely, Michael S. Wolfe, Ralph H. Hruban, Douglas W. Ball, Roland M. Schmid, Steven D. Leach - Cancer Cell 2003 cited by 637

  22. Notch Signaling Augments T Cell Responsiveness by Enhancing CD25 Expression

    Authors: Scott Adler, Elise Chiffoleau, Lanwei Xu, Nicole M. Dalton, Jennifer M. Burg, Andrew D. Wells, Michael S. Wolfe, Laurence A. Turka, Warren S. Pear - The Journal of Immunology 2003 cited by 219

  23. Alzheimer Presenilin-1 Mutations Dramatically Reduce Trimming of Long Amyloid β-Peptides (Aβ) by γ-Secretase to Increase 42-to-40-Residue Aβ

    Authors: Marty A. Fernandez, Julia A. Klutkowski, Taylor Freret, Michael S. Wolfe - Journal of Biological Chemistry 2014 cited by 138

  24. Structural Basis for Stabilization of the Tau Pre-mRNA Splicing Regulatory Element by Novantrone (Mitoxantrone)

    Authors: Suxin Zheng, Yu Chen, Christine P. Donahue, Michael S. Wolfe, Gabriele Varani - Chemistry & Biology 2009 cited by 96