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Steven D. Leach

Active 1988–2024

81
Papers
27,819
Citations
72
h-index
80
i10-index

Citations

Citations per year for Steven D. Leach1939: 1 citations1985: 1 citations1989: 1 citations1990: 1 citations1991: 1 citations1992: 2 citations1993: 2 citations1994: 3 citations1995: 6 citations1996: 4 citations1997: 7 citations1998: 14 citations1999: 29 citations2000: 48 citations2001: 58 citations2002: 70 citations2003: 76 citations2004: 87 citations2005: 131 citations2006: 134 citations2007: 144 citations2008: 156 citations2009: 281 citations2010: 293 citations2011: 324 citations2012: 268 citations2013: 314 citations2014: 337 citations2015: 377 citations2016: 387 citations2017: 391 citations2018: 369 citations2019: 1,012 citations2020: 1,142 citations2021: 1,175 citations2022: 853 citations2023: 686 citations2024: 831 citations2025: 420 citations2026: 15 citations1940–1984: no citations, so these years are not shown1986–1988: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 4,502 citing papers, 33.5% of this breakdownChina: 1,584 citing papers, 11.8% of this breakdownGermany: 927 citing papers, 6.9% of this breakdownUnited Kingdom: 800 citing papers, 6% of this breakdownJapan: 537 citing papers, 4% of this breakdownItaly: 500 citing papers, 3.7% of this breakdownCanada: 435 citing papers, 3.2% of this breakdownFrance: 409 citing papers, 3% of this breakdownSpain: 343 citing papers, 2.6% of this breakdownNetherlands: 342 citing papers, 2.5% of this breakdownAustralia: 321 citing papers, 2.4% of this breakdownSwitzerland: 263 citing papers, 2% of this breakdown
0%33.5%Other 18.4%

Institutions

Fields

  • Medicine50.6%
  • Biochemistry, Genetics and Molecular Biology36.1%
  • Immunology and Microbiology5.5%
  • Chemistry2.4%
  • Engineering2%
  • Neuroscience1.4%
  • Other2%

Topics

  • Pancreatic and Hepatic Oncology Research9%
  • Cancer Cells and Metastasis5.3%
  • Cancer Genomics and Diagnostics4.5%
  • Cancer Immunotherapy and Biomarkers2.7%
  • Epigenetics and DNA Methylation2.7%
  • Pancreatic function and diabetes2.3%
  • Other73.5%

Coauthors

All papers

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  1. Organoid Models of Human and Mouse Ductal Pancreatic Cancer

    Authors: Sylvia F. Boj, Chang‐Il Hwang, Lindsey A. Baker, Iok In Christine Chio, Dannielle D. Engle, Vincenzo Corbo, Myrthe Jager, Mariano Ponz‐Sarvisé, Hervé Tiriac, Mona S. Spector, Ana Gudelj Gračanin, Tobiloba E. Oni, Kenneth H. Yu, Ruben van Boxtel, Meritxell Huch, Keith Rivera, John P. Wilson, Michael E. Feigin, Daniel Öhlund, Abram Handly-Santana, Christine Ardito-Abraham, Michael Ludwig, Ela Elyada, Brinda Alagesan, Giulia Biffi, Georgi N. Yordanov, Bethany Delcuze, Brianna Creighton, Kevin Wright, Youngkyu Park, Folkert H.M. Morsink, I. Quintus Molenaar, Inne H. Borel Rinkes, Edwin Cuppen, Hao Yuan, Ying Jin, Isaäc J. Nijman, Christine A. Iacobuzio–Donahue, Steven D. Leach, Darryl Pappin, Molly Hammell, David S. Klimstra, Olca Baştürk, Ralph H. Hruban, G. Johan A. Offerhaus, Robert G. Vries, Hans Clevers, David A. Tuveson - Cell 2014 cited by 2,196

  2. EMT and Dissemination Precede Pancreatic Tumor Formation

    Authors: Andrew D. Rhim, Emily T. Mirek, Nicole M. Aiello, Anirban Maitra, Jennifer M. Bailey, Florencia McAllister, Maximilian Reichert, Gregory L. Beatty, Anil K. Rustgi, Robert H. Vonderheide, Steven D. Leach, Ben Z. Stanger - Cell 2012 cited by 2,138

  3. Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer

    Authors: Australian Pancreatic Cancer Genome Initiative, Vinod P. Balachandran, Marta Łuksza, Julia N. Zhao, Vladimir Makarov, John A. Moral, Romain Remark, Brian Herbst, Gökçe Aşkan, Umesh Bhanot, Yasin Şenbabaoğlu, Daniel K. Wells, Charles Ian Ormsby Cary, Olivera Grbovic-Huezo, Marc A. Attiyeh, Benjamin D. Medina, Jennifer Zhang, Jennifer K. Loo, Joseph A. Saglimbeni, Mohsen Abu-Akeel, Roberta Zappasodi, Nadeem Riaz, Martin Smoragiewicz, Zakiya Kelley, Olca Baştürk, Mithat Gönen, Arnold J. Levine, Peter J. Allen, Douglas T. Fearon, Miriam Mérad, Sacha Gnjatic, Christine A. Iacobuzio–Donahue, Jedd D. Wolchok, Ronald P. DeMatteo, Timothy A. Chan, Benjamin D. Greenbaum, Taha Merghoub, Steven D. Leach - Nature 2017 cited by 1,229

  4. Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

    Authors: Siân Jones, Xiaosong Zhang, D. Williams Parsons, Jimmy Lin, Rebecca Leary, Philipp Angenendt, Parminder K. Mankoo, Hannah Carter, Hirohiko Kamiyama, Antonio Jimeno, Seung‐Mo Hong, Baojin Fu, Ming‐Tseh Lin, Eric S. Calhoun, Mihoko Kamiyama, Kimberly Walter, Tatiana Nikolskaya, Yuri Nikolsky, James Hartigan, Douglas R. Smith, Manuel Hidalgo, Steven D. Leach, Alison P. Klein, Elizabeth M. Jaffee, Michael Goggins, Anirban Maitra, Christine A. Iacobuzio–Donahue, James R. Eshleman, Scott E. Kern, Ralph H. Hruban, Rachel Karchin, Nickolas Papadopoulos, Giovanni Parmigiani, Bert Vogelstein, Victor E. Velculescu, Kenneth W. Kinzler - Science 2008 cited by 4,055

  5. A draft map of the human proteome

    Authors: Min‐Sik Kim, Sneha M. Pinto, Derese Getnet, Raja Sekhar Nirujogi, Srikanth S. Manda, Raghothama Chaerkady, Anil K. Madugundu, Dhanashree Kelkar, Ruth Isserlin, Shobhit Jain, Joji Kurian Thomas, Babylakshmi Muthusamy, Pamela Leal, Praveen Kumar, Nandini A. Sahasrabuddhe, Lavanya Balakrishnan, Jayshree Advani, Bijesh George, Santosh Renuse, Lakshmi Dhevi N. Selvan, Arun H. Patil, Vishalakshi Nanjappa, Aneesha Radhakrishnan, Samarjeet Prasad, Tejaswini Subbannayya, Rajesh Raju, Manish Kumar, Sreelakshmi K. Sreenivasamurthy, Arivusudar Marimuthu, Gajanan Sathe, Sandip Chavan, Keshava K. Datta, Yashwanth Subbannayya, Apeksha Sahu, Soujanya D. Yelamanchi, Savita Jayaram, Pavithra Rajagopalan, Jyoti Sharma, Krishna R. Murthy, Nazia Syed, Renu Goel, Aafaque Ahmad Khan, Sartaj Ahmad, Gourav Dey, Keshav Mudgal, Aditi Chatterjee, Tai‐Chung Huang, Jun Zhong, Xinyan Wu, Patrick G. Shaw, Donald Freed, Muhammad Saddiq Zahari, Kanchan K. Mukherjee, Subramanian Shankar, Anita Mahadevan, Henry Lam, Chris J. Mitchell, Susarla Krishna Shankar, Parthasarathy Satishchandra, John T. Schroeder, Ravi Sirdeshmukh, Anirban Maitra, Steven D. Leach, Charles G. Drake, Marc K. Halushka, Thottethodi Subrahmanya Keshava Prasad, Ralph H. Hruban, Candace L. Kerr, Gary D. Bader, Christine A. Iacobuzio–Donahue, Harsha Gowda, Akhilesh Pandey - Nature 2014 cited by 2,311

  6. A gene–environment-induced epigenetic program initiates tumorigenesis

    Authors: Direna Alonso‐Curbelo, Yu-Jui Ho, Cassandra Burdziak, Jesper L.V. Mååg, John P. Morris, Rohit Chandwani, Hsuan-An Chen, Kaloyan M. Tsanov, Francisco M. Barriga, Wei Luan, Nilgun Tasdemir, Geulah Livshits, Elham Azizi, Jaeyoung Chun, John E. Wilkinson, Linas Mažutis, Steven D. Leach, Richard P. Koche, Dana Pe’er, Scott W. Lowe - Nature 2021 cited by 321

  7. ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity

    Authors: John A. Moral, Joanne Leung, Luis A. Rojas, Jennifer Jin Ruan, Julia N. Zhao, Zachary Sethna, Anita Ramnarain, Billel Gasmi, Murali Gururajan, David Redmond, Gökçe Aşkan, Umesh Bhanot, Ela Elyada, Youngkyu Park, David A. Tuveson, Mithat Gönen, Steven D. Leach, Jedd D. Wolchok, Ronald P. DeMatteo, Taha Merghoub, Vinod P. Balachandran - Nature 2020 cited by 341

  8. α-Ketoglutarate links p53 to cell fate during tumour suppression

    Authors: John P. Morris, Jossie J. Yashinskie, Richard P. Koche, Rohit Chandwani, Sha Tian, Chi-Chao Chen, Timour Baslan, Zoran S. Marinkovic, Francisco J. Sánchez‐Rivera, Steven D. Leach, Carlos Carmona‐Fontaine, Craig B. Thompson, Lydia W.S. Finley, Scott W. Lowe - Nature 2019 cited by 299

  9. Oncogenic Kras Activates a Hematopoietic-to-Epithelial IL-17 Signaling Axis in Preinvasive Pancreatic Neoplasia

    Authors: Florencia McAllister, Jennifer M. Bailey, Janivette Alsina, Christopher J. Nirschl, Rajni Sharma, Hongni Fan, Yanique Rattigan, Jeffrey C. Roeser, Rachana H. Lankapalli, Hao Zhang, Elizabeth M. Jaffee, Charles G. Drake, Franck Housseau, Anirban Maitra, Jay K. Kolls, Cynthia L. Sears, Drew M. Pardoll, Steven D. Leach - Cancer Cell 2014 cited by 405

  10. Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing

    Authors: Diana Mandelker, Liying Zhang, Yelena Kemel, Zsofia K. Stadler, Joseph Vijai, Ahmet Zehir, Nisha Pradhan, Angela G. Arnold, Michael F. Walsh, Yirong Li, Anoop R. Balakrishnan, Aijazuddin Syed, Meera Prasad, Khédoudja Nafa, Maria I. Carlo, Karen A. Cadoo, Meg Sheehan, Megan Harlan Fleischut, Erin Salo‐Mullen, Magan Trottier, Steven M. Lipkin, Anne Lincoln, Semanti Mukherjee, Vignesh Ravichandran, Roy Cambria, Jesse Galle, Wassim Abida, Marcia E. Arcila, Ryma Benayed, Ronak Shah, Kenneth H. Yu, Dean F. Bajorin, Jonathan Coleman, Steven D. Leach, Maeve A. Lowery, Julio García‐Aguilar, Philip W. Kantoff, Charles L. Sawyers, Maura N. Dickler, Leonard B. Saltz, Robert J. Motzer, Eileen M. O’Reilly, Howard I. Scher, José Baselga, David S. Klimstra, David B. Solit, David M. Hyman, Michael F. Berger, Marc Ladanyi, Mark E. Robson, Kenneth Offit - JAMA 2017 cited by 523

  11. Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer

    Authors: Luisa F. Escobar‐Hoyos, Alex Penson, Ram Kannan, Hana Cho, Chun‐Hao Pan, Rohit K. Singh, Lisa Helene Apken, G. Aaron Hobbs, Renhe Luo, Nicolas Lecomte, Sruthi Babu, Fong Cheng Pan, Direna Alonso‐Curbelo, John P. Morris, Gökçe Aşkan, Olivera Grbovic-Huezo, Paul Ogrodowski, Jonathan Bermeo, Joseph A. Saglimbeni, Cristian D. Cruz, Yu-Jui Ho, Sharon Lawrence, Jerry P. Melchor, Grant A. Goda, Karen Bai, Alessandro Pastore, Simon J. Hogg, Srivatsan Raghavan, Peter J. Bailey, David K. Chang, Andrew V. Biankin, Kenneth R. Shroyer, Brian M. Wolpin, Andrew J. Aguirre, Andrea Ventura, Barry S. Taylor, Channing J. Der, Daniel Domínguez, Daniel Kümmel, Andrea Oeckinghaus, Scott W. Lowe, Robert K. Bradley, Omar Abdel‐Wahab, Steven D. Leach - Cancer Cell 2020 cited by 158

  12. A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS

    Authors: Xiaohua Duan, Tuo Zhang, Lingling Feng, Neranjan de Silva, Benjamin C. Greenspun, Xing Wang, Jenna E. Moyer, M. Laura Martin, Rohit Chandwani, Olivier Elemento, Steven D. Leach, Todd Evans, Shuibing Chen, Fong Cheng Pan - Cell stem cell 2023 cited by 72

  13. Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells

    Authors: Yu Zhang, Michelle Zoltan, Erick Riquelme, Hanwen Xu, İsmet Şahin, Susana Castro-Pando, Maria Fernanda Montiel, Kyle Chang, Zhengyu Jiang, Jianhua Ling, Sonal Gupta, William Horne, Melissa Pruski, Huamin Wang, Shao‐Cong Sun, Guillermina Lozano, Paul J. Chiao, Anirban Maitra, Steven D. Leach, Jay K. Kolls, Eduardo Vilar, Timothy C. Wang, Jennifer M. Bailey, Florencia McAllister - Gastroenterology 2018 cited by 157

  14. EIF1AX and RAS Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC

    Authors: Gnana P. Krishnamoorthy, Natalie R. Davidson, Steven D. Leach, Zhen Zhao, Scott W. Lowe, Gina Lee, Iñigo Landa, James Nagarajah, Mahesh Saqcena, Kamini Singh, Hans-Guido Wendel, Snjezana Doğan, Prasanna P. Tamarapu, John Blenis, Ronald Ghossein, Jeffrey A. Knauf, Gunnar Rätsch, James A. Fagin - Cancer Discovery 2018 cited by 92

  15. Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE).

    Authors: Pedram Argani, Christine A. Iacobuzio–Donahue, Byungwoo Ryu, Christophe Rosty, Michael Goggins, Robb E. Wilentz, Selva R. Murugesan, Steven D. Leach, Elizabeth M. Jaffee, Charles J. Yeo, John L. Cameron, Scott E. Kern, Ralph H. Hruban - 2001 cited by 578

  16. Transactivation from Gal4-VP16 transgenic insertions for tissue-specific cell labeling and ablation in zebrafish

    Authors: Jon M. Davison, Courtney M. Akitake, Mary Goll, Jerry M. Rhee, Nathan J. Gosse, Herwig Baier, Marnie E. Halpern, Steven D. Leach, Michael J. Parsons - Developmental Biology 2007 cited by 464

  17. Expression of Activated Ras in Gastric Chief Cells of Mice Leads to the Full Spectrum of Metaplastic Lineage Transitions

    Authors: Eunyoung Choi, Audrey M. Hendley, Jennifer M. Bailey, Steven D. Leach, James R. Goldenring - Gastroenterology 2015 cited by 162

  18. Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice

    Authors: Nils Habbe, Guanglu Shi, Robert A. Meguid, Volker Fendrich, Farzad Esni, Huiping Chen, Georg Feldmann, Doris A. Stoffers, Stephen F. Konieczny, Steven D. Leach, Anirban Maitra - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 412

  19. Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms

    Authors: Maeve A. Lowery, Winston Wong, Emmet Jordan, Jonathan W. Lee, Yelena Kemel, Joseph Vijai, Diana Mandelker, Ahmet Zehir, Marinela Capanu, Erin Salo‐Mullen, Angela G. Arnold, Kenneth H. Yu, Anna M. Varghese, David P. Kelsen, Robin Brenner, Erica Kaufmann, Vignesh Ravichandran, Semanti Mukherjee, Michael F. Berger, David M. Hyman, David S. Klimstra, Ghassan K. Abou‐Alfa, Catherine Tjan, Christina M. Covington, Hannah Maynard, Peter J. Allen, Gökçe Aşkan, Steven D. Leach, Christine A. Iacobuzio–Donahue, Mark E. Robson, Kenneth Offit, Zsofia K. Stadler, Eileen M. O’Reilly - JNCI Journal of the National Cancer Institute 2018 cited by 224

  20. Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas

    Authors: Michael J. Parsons, Harshan Pisharath, Shamila Yusuff, John C. Moore, Arndt F. Siekmann, Nathan D. Lawson, Steven D. Leach - Mechanisms of Development 2009 cited by 370

  21. Stratification of Pancreatic Ductal Adenocarcinoma: Combinatorial Genetic, Stromal, and Immunologic Markers

    Authors: Erik S. Knudsen, Paris Vail, Uthra Balaji, Hoai Ngo, Ihab W. Botros, Vladimir Makarov, Nadeem Riaz, Vinod P. Balachandran, Steven D. Leach, Debrah M. Thompson, Timothy A. Chan, Agnieszka K. Witkiewicz - Clinical Cancer Research 2017 cited by 190

  22. Sympathetic Innervation during Development Is Necessary for Pancreatic Islet Architecture and Functional Maturation

    Authors: Philip M. Borden, Jessica Houtz, Steven D. Leach, Rejji Kuruvilla - Cell Reports 2013 cited by 188

  23. p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells

    Authors: Jennifer M. Bailey, Audrey M. Hendley, Kelly J. Lafaro, Melissa Pruski, Neal C. Jones, Janivette Alsina, Mamoun Younes, Anirban Maitra, Fiona E. McAllister, Christine A. Iacobuzio–Donahue, Steven D. Leach - Oncogene 2015 cited by 157

  24. Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules

    Authors: Kamini Singh, Jianan Lin, Nicolas Lecomte, Prathibha Mohan, Gokce Askan, Viraj R. Sanghvi, Man Jiang, Olivera Grbovic-Huezo, Antonija Burčul, Stefan G. Stark, Paul B. Romesser, Qing Chang, Jerry P. Melchor, Rachel K. Beyer, Mark E. Duggan, Yoshiyuki Fukase, Guangli Yang, Ouathek Ouerfelli, Agnès Viale, Elisa de Stanchina, Andrew W. Stamford, Peter T. Meinke, Gunnar Rätsch, Steven D. Leach, Zhengqing Ouyang, Hans‐Guido Wendel - Cancer Research 2021 cited by 38