David A. Tuveson
Active 1991–2025
- 179
- Papers
- 82,477
- Citations
- 112
- h-index
- 176
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine48.3%
- Biochemistry, Genetics and Molecular Biology37.9%
- Immunology and Microbiology6.8%
- Engineering2.7%
- Neuroscience1%
- Materials Science0.8%
- Other2.5%
Topics
- Pancreatic and Hepatic Oncology Research5.4%
- Cancer Cells and Metastasis5.2%
- Cancer, Hypoxia, and Metabolism2.9%
- Epigenetics and DNA Methylation2.7%
- Cancer Immunotherapy and Biomarkers2.7%
- Immune cells in cancer2.7%
- Other78.4%
Coauthors
- Youngkyu Park23
- Hervé Tiriac20
- Tyler Jacks15
- Sunil R. Hingorani13
- Albrecht Neeße12
- Dannielle D. Engle12
- Dennis Plenker12
- Kristopher K. Frese12
- Ralph H. Hruban12
- Aarthi Gopinathan11
- Douglas T. Fearon11
- Giulia Biffi10
- Chang‐Il Hwang9
- Daniel Öhlund9
- Duncan I. Jodrell9
- Gina M. DeNicola9
- Michael A. Jacobetz9
- Natalie Cook9
- Pedro A. Pérez–Mancera9
- Christine Feig8
- Christopher R. Vakoc8
- Ela Elyada8
- Florian A. Karreth8
- Hans Clevers8
All papers
- A framework for advancing our understanding of cancer-associated fibroblasts
Authors: Erik Sahai, Igor Astsaturov, Edna Cukierman, David G. DeNardo, Mikala Egeblad, Ronald M. Evans, Douglas T. Fearon, Florian R. Greten, Sunil R. Hingorani, Tony Hunter, Richard O. Hynes, Rakesh K. Jain, Tobias Janowitz, Claus Jørgensen, Alec C. Kimmelman, Mikhail G. Kolonin, Robert G. Maki, Scott Powers, Ellen Puré, Daniel C. Ramirez, Ruth Scherz‐Shouval, Mara H. Sherman, Sheila A. Stewart, Thea D. Tlsty, David A. Tuveson, Fiona M. Watt, Valerie M. Weaver, Ashani T. Weeraratna, Zena Werb - Nature reviews. Cancer 2020 cited by 3,780
- Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts
Authors: Ela Elyada, Mohan Bolisetty, Pasquale Laise, William F. Flynn, Elise T. Courtois, Richard A. Burkhart, Jonathan A. Teinor, Pascal Belleau, Giulia Biffi, Matthew S. Lucito, Santhosh Sivajothi, Todd D. Armstrong, Dannielle D. Engle, Kenneth H. Yu, Hao Yuan, Christopher L. Wolfgang, Youngkyu Park, Jonathan Preall, Elizabeth M. Jaffee, Andrea Califano, Paul Robson, David A. Tuveson - Cancer Discovery 2019 cited by 2,148
- Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
Authors: Daniel Öhlund, Abram Handly-Santana, Giulia Biffi, Ela Elyada, Ana S. Almeida, Mariano Ponz‐Sarvisé, Vincenzo Corbo, Tobiloba E. Oni, Stephen Hearn, Eun Jung Lee, Iok In Christine Chio, Chang‐Il Hwang, Hervé Tiriac, Lindsey A. Baker, Dannielle D. Engle, Christine Feig, Anne Kultti, Mikala Egeblad, Douglas T. Fearon, James M. Crawford, Hans Clevers, Youngkyu Park, David A. Tuveson - The Journal of Experimental Medicine 2017 cited by 2,487
- Transcriptional Regulation by Nrf2
Authors: Claudia Tonelli, Iok In Christine Chio, David A. Tuveson - Antioxidants and Redox Signaling 2017 cited by 2,166
- Diversity and Biology of Cancer-Associated Fibroblasts
Authors: Giulia Biffi, David A. Tuveson - Physiological Reviews 2020 cited by 1,251
- IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma
Authors: Giulia Biffi, Tobiloba E. Oni, Benjamin Spielman, Hao Yuan, Ela Elyada, Youngkyu Park, Jonathan Preall, David A. Tuveson - Cancer Discovery 2018 cited by 1,290
- Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti–PD-L1 immunotherapy in pancreatic cancer
Authors: Christine Feig, James O. Jones, Matthew Kraman, R. J. Wells, Andrew Deonarine, Derek Chan, Claire M. Connell, Edward W. Roberts, Qi Zhao, Otávia L. Caballero, Sarah A. Teichmann, Tobias Janowitz, Duncan I. Jodrell, David A. Tuveson, Douglas T. Fearon - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 2,011
- Organoid Models of Human and Mouse Ductal Pancreatic Cancer
Authors: Sylvia F. Boj, Chang‐Il Hwang, Lindsey A. Baker, Iok In Christine Chio, Dannielle D. Engle, Vincenzo Corbo, Myrthe Jager, Mariano Ponz‐Sarvisé, Hervé Tiriac, Mona S. Spector, Ana Gudelj Gračanin, Tobiloba E. Oni, Kenneth H. Yu, Ruben van Boxtel, Meritxell Huch, Keith Rivera, John P. Wilson, Michael E. Feigin, Daniel Öhlund, Abram Handly-Santana, Christine Ardito-Abraham, Michael Ludwig, Ela Elyada, Brinda Alagesan, Giulia Biffi, Georgi N. Yordanov, Bethany Delcuze, Brianna Creighton, Kevin Wright, Youngkyu Park, Folkert H.M. Morsink, I. Quintus Molenaar, Inne H. Borel Rinkes, Edwin Cuppen, Hao Yuan, Ying Jin, Isaäc J. Nijman, Christine A. Iacobuzio–Donahue, Steven D. Leach, Darryl Pappin, Molly Hammell, David S. Klimstra, Olca Baştürk, Ralph H. Hruban, G. Johan A. Offerhaus, Robert G. Vries, Hans Clevers, David A. Tuveson - Cell 2014 cited by 2,196
- Pancreatic cancer
Authors: Jörg Kleeff, Murray Korc, Minoti V. Apte, Carlo La Vecchia, Colin Johnson, Andrew V. Biankin, Rachel Ε. Neale, Margaret A. Tempero, David A. Tuveson, Ralph H. Hruban, John P. Neoptolemos - Nature Reviews Disease Primers 2016 cited by 1,873
- Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
Authors: Sunil R. Hingorani, Lifu Wang, Asha S. Multani, Chelsea Combs, Thérèse B. Deramaudt, Ralph H. Hruban, Anil K. Rustgi, Sandy Chang, David A. Tuveson - Cancer Cell 2005 cited by 2,629
- Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer
Authors: Hervé Tiriac, Pascal Belleau, Dannielle D. Engle, Dennis Plenker, Astrid Deschênes, Tim D.D. Somerville, Fieke E. M. Froeling, Richard A. Burkhart, Robert E. Denroche, Gun-Ho Jang, Koji Miyabayashi, C. Megan Young, Hardik J. Patel, Michelle Ma, Joseph F. LaComb, Randze Lerie D. Palmaira, Ammar A. Javed, Jasmine C. Huynh, Molly Johnson, Kanika Arora, Nicolas Robine, Minita Shah, Rashesh Sanghvi, Austin Goetz, Cinthya Y. Lowder, Laura Martello, Else Driehuis, Nicolas Lecomte, Gökçe Aşkan, Christine A. Iacobuzio–Donahue, Hans Clevers, Laura D. Wood, Ralph H. Hruban, Elizabeth D. Thompson, Andrew J. Aguirre, Brian M. Wolpin, Aaron R. Sasson, Joseph Kim, Maoxin Wu, Juan Carlos Bucobo, Peter J. Allen, Divyesh V. Sejpal, William H. Nealon, J. D. Sullivan, Jordan M. Winter, Phyllis A. Gimotty, Jean L. Grem, Dominick J. DiMaio, Jonathan M. Buscaglia, Paul M. Grandgenett, Jonathan R. Brody, Michael A. Hollingsworth, Grainne M. O’Kane, Faiyaz Notta, Edward Kim, James M. Crawford, Craig Devoe, Allyson J. Ocean, Christopher L. Wolfgang, Kenneth H. Yu, Ellen Li, Christopher R. Vakoc, Benjamin Hubert, Sandra E. Fischer, Julie M. Wilson, Richard A. Moffitt, Jennifer J. Knox, Alexander Krasnitz, Steven Gallinger, David A. Tuveson - Cancer Discovery 2018 cited by 1,094
- Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
Authors: Gina M. DeNicola, Florian A. Karreth, Timothy J. Humpton, Aarthi Gopinathan, Cong Wei, Kristopher K. Frese, Dipti Mangal, Kenneth H. Yu, Charles J. Yeo, Eric S. Calhoun, Francesca Scrimieri, Jordan M. Winter, Ralph H. Hruban, Christine A. Iacobuzio–Donahue, Scott E. Kern, Ian A. Blair, David A. Tuveson - Nature 2011 cited by 2,276
- Activated fibroblasts in cancer: Perspectives and challenges
Authors: Giuseppina Caligiuri, David A. Tuveson - Cancer Cell 2023 cited by 394
- Cancer modeling meets human organoid technology
Authors: David A. Tuveson, Hans Clevers - Science 2019 cited by 952
- Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
Authors: Kenneth P. Olive, Michael A. Jacobetz, Christian J. Davidson, Aarthi Gopinathan, Dominick J. O. McIntyre, Davina J. Honess, Basetti Madhu, Mae A. Goldgraben, Meredith E. Caldwell, David Allard, Kristopher K. Frese, Gina M. DeNicola, Christine Feig, Chelsea Combs, Stephen P. Winter, Heather Ireland‐Zecchini, Stefanie Reichelt, William Howat, Alex Chang, Mousumi Dhara, Lifu Wang, Felix Rückert, Robert Grützmann, Christian Pilarsky, Kamel Izeradjene, Sunil R. Hingorani, Pearl S. Huang, Susan Davies, William Plunkett, Merrill J. Egorin, Ralph H. Hruban, Nigel Whitebread, Karen McGovern, Julian Adams, Christine A. Iacobuzio–Donahue, John R. Griffiths, David A. Tuveson - Science 2009 cited by 3,164
- Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy
Authors: Mara H. Sherman, Ruth T. Yu, Dannielle D. Engle, Ning Ding, Annette R. Atkins, Hervé Tiriac, Eric A. Collisson, Frances Connor, Terry Van Dyke, С. В. Козлов, Philip Martin, Tiffany Tseng, David W. Dawson, Timothy R. Donahue, Atsushi Masamune, Tooru Shimosegawa, Minoti V. Apte, Jeremy S. Wilson, Beverly Ng, Sue Lynn Lau, Jenny E. Gunton, Geoffrey M. Wahl, Tony Hunter, Jeffrey A. Drebin, Peter J. O’Dwyer, Christopher Liddle, David A. Tuveson, Michael Downes, Ronald M. Evans - Cell 2014 cited by 1,137
- Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution
Authors: Michelle Chan‐Seng‐Yue, Jaeseung Kim, Gavin W. Wilson, Karen Ng, Eugenia Flores‐Figueroa, Grainne M. O’Kane, Ashton A. Connor, Robert E. Denroche, Robert C. Grant, Jessica McLeod, Julie M. Wilson, Gun Ho Jang, Amy Zhang, Anna Dodd, Sheng‐Ben Liang, Ayelet Borgida, Dianne Chadwick, Sangeetha Kalimuthu, Ilinca M. Lungu, John M.S. Bartlett, Paul M. Krzyzanowski, Vandana Sandhu, Hervé Tiriac, Fieke E. M. Froeling, Joanna M. Karasinska, James T. Topham, Daniel J. Renouf, David F. Schaeffer, Steven J.M. Jones, Marco A. Marra, Janessa Laskin, Runjan Chetty, Lincoln Stein, George Zogopoulos, Benjamin Haibe‐Kains, Peter J. Campbell, David A. Tuveson, Jennifer J. Knox, Sandra E. Fischer, Steven Gallinger, Faiyaz Notta - Nature Genetics 2020 cited by 689
- Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
Authors: Sunil R. Hingorani, Emanuel F. Petricoin, Anirban Maitra, Vinodh N. Rajapakse, Catrina E. King, Michael A. Jacobetz, Sally Ross, Thomas P. Conrads, Timothy D. Veenstra, Ben A. Hitt, Yoshiya Kawaguchi, Don Johann, Lance A. Liotta, Howard C. Crawford, Mary Putt, Tyler Jacks, Christopher V.E. Wright, Ralph H. Hruban, Andrew M. Lowy, David A. Tuveson - Cancer Cell 2003 cited by 2,488
- Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein–α
Authors: Matthew Kraman, Paul Bambrough, James N. Arnold, Edward W. Roberts, Łukasz Magiera, James O. Jones, Aarthi Gopinathan, David A. Tuveson, Douglas T. Fearon - Science 2010 cited by 1,141
- Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction
Authors: Corina Amor, Inés Fernández-Maestre, Saria Chowdhury, Yu-Jui Ho, Sandeep Nadella, Courtenay Graham, Sebastian E. Carrasco, Emmanuella Nnuji-John, Judith Feucht, Clemens Hinterleitner, Valentin J.A. Barthet, Jacob A. Boyer, Riccardo Mezzadra, Matthew Wereski, David A. Tuveson, Ross L. Levine, Lee W. Jones, Michel Sadelain, Scott W. Lowe - Nature Aging 2024 cited by 184
- Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
Authors: Michael A. Jacobetz, Derek Chan, Albrecht Neeße, Tashinga E. Bapiro, Natalie Cook, Kristopher K. Frese, Christine Feig, Tomoaki Nakagawa, Meredith E. Caldwell, Heather Zecchini, Martijn P. Lolkema, Ping Jiang, Anne Kultti, Curtis B. Thompson, Daniel C. Maneval, Duncan I. Jodrell, Gregory I Frost, H. Michael Shepard, Jeremy N. Skepper, David A. Tuveson - Gut 2012 cited by 1,083
- Restoration of p53 function leads to tumour regression in vivo
Authors: Andrea Ventura, David G. Kirsch, Margaret E. McLaughlin, David A. Tuveson, Jan Grimm, Laura Lintault, Jamie J. Newman, Elizabeth E. Reczek, Ralph Weissleder, Tyler Jacks - Nature 2007 cited by 1,855
- Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
Authors: Erica L. Jackson, Nicholas A. Willis, Kim L. Mercer, Roderick T. Bronson, Denise Crowley, R Montoya, Tyler Jacks, David A. Tuveson - Genes & Development 2001 cited by 1,971
- Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cells
Authors: Chenxi Tian, Karl R. Clauser, Daniel Öhlund, Steffen Rickelt, Ying Huang, Mala Gupta, D.R. Mani, Steven A. Carr, David A. Tuveson, Richard O. Hynes - National Academy of Sciences, Proceedings of the National Academy of Sciences 2019 cited by 432
