Michel Sadelain
Active 1990–2026
- 173
- Papers
- 59,152
- Citations
- 107
- h-index
- 169
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine59.3%
- Biochemistry, Genetics and Molecular Biology25.7%
- Immunology and Microbiology9.3%
- Neuroscience2.3%
- Engineering1.9%
- Materials Science0.5%
- Other1%
Topics
- CAR-T cell therapy research16.3%
- Virus-based gene therapy research5.6%
- Immune Cell Function and Interaction5.6%
- Immunotherapy and Immune Responses5.2%
- CRISPR and Genetic Engineering4%
- Cancer Immunotherapy and Biomarkers3.5%
- Other59.8%
Coauthors
- Isabelle Rivière50
- Renier J. Brentjens37
- Jae H. Park22
- Xiuyan Wang20
- Jorge Mansilla‐Soto18
- Elizabeth Halton13
- Miguel‐Angel Perales12
- Mohamad Hamieh12
- Anton Dobrin11
- Brigitte Sénéchal11
- Judith Feucht11
- Mithat Gönen10
- Prasad S. Adusumilli10
- Craig S. Sauter9
- Gertrude Gunset9
- Justin Eyquem9
- Kevin J. Curran9
- M. Lia Palomba9
- Marco L. Davila9
- Steven M. Larson9
- Theodoros Giavridis9
- Yvette Bernal9
- Eirini P. Papapetrou8
- Zeguo Zhao8
All papers
- Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer
Authors: Luis A. Rojas, Zachary Sethna, Kevin C. Soares, Cristina Olcese, Nan Pang, Erin Patterson, Jayon Lihm, Nicholas Ceglia, Pablo Guasp, Alexander L. Chu, Rebecca Yu, Adrienne Kaya Chandra, Theresa Waters, Jennifer Jin Ruan, Masataka Amisaki, Abderezak Zebboudj, Zagaa Odgerel, George C. Payne, Evelyna Derhovanessian, Felicitas Müller, Ina Rhee, Mahesh Yadav, Anton Dobrin, Michel Sadelain, Marta Łuksza, Noah A. Cohen, Laura H. Tang, Olca Baştürk, Mithat Gönen, Seth S. Katz, Richard Kinh Gian, Andrew S. Epstein, Parisa Momtaz, Wungki Park, Ryan Sugarman, Anna M. Varghese, Elizabeth Won, Avni M. Desai, Alice C. Wei, Michael I. D’Angelica, T. Peter Kingham, Ira Mellman, Taha Merghoub, Jedd D. Wolchok, Uğur Şahin, Özlem Türeci, Benjamin D. Greenbaum, William R. Jarnagin, Jeffrey A. Drebin, Eileen M. O’Reilly, Vinod P. Balachandran - Nature 2023 cited by 1,350
- Senolytic CAR T cells reverse senescence-associated pathologies
Authors: Corina Amor, Judith Feucht, Josef Leibold, Yu-Jui Ho, Changyu Zhu, Direna Alonso‐Curbelo, Jorge Mansilla‐Soto, Jacob A. Boyer, Xiang Li, Theodoros Giavridis, Amanda Kulick, Shauna L Houlihan, Ellinor I.B. Peerschke, Scott L. Friedman, Vladimir Ponomarev, Alessandra Piersigilli, Michel Sadelain, Scott W. Lowe - Nature 2020 cited by 1,079
- Chimeric Antigen Receptor Therapy
Authors: Carl H. June, Michel Sadelain - New England Journal of Medicine 2018 cited by 2,280
- Cytokine release syndrome and associated neurotoxicity in cancer immunotherapy
Authors: Emma Morris, Sattva S. Neelapu, Theodoros Giavridis, Michel Sadelain - Nature reviews. Immunology 2021 cited by 1,039
- Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia
Authors: Jae H. Park, Isabelle Rivière, Mithat Gönen, Xiuyan Wang, Brigitte Sénéchal, Kevin J. Curran, Craig S. Sauter, Yongzeng Wang, Bianca Santomasso, Elena Mead, Mikhail Roshal, P. Maslak, Marco L. Davila, Renier J. Brentjens, Michel Sadelain - New England Journal of Medicine 2018 cited by 2,675
- Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
Authors: Justin Eyquem, Jorge Mansilla‐Soto, Theodoros Giavridis, Sjoukje J. C. van der Stegen, Mohamad Hamieh, Kristen Cunanan, Ashlesha Odak, Mithat Gönen, Michel Sadelain - Nature 2017 cited by 1,854
- Gene therapy comes of age
Authors: Cynthia E. Dunbar, Katherine A. High, J. Keith Joung, Donald B. Kohn, Keiya Ozawa, Michel Sadelain - Science 2018 cited by 1,378
- CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade
Authors: Theodoros Giavridis, Sjoukje J. C. van der Stegen, Justin Eyquem, Mohamad Hamieh, Alessandra Piersigilli, Michel Sadelain - Nature Medicine 2018 cited by 1,262
- The Basic Principles of Chimeric Antigen Receptor Design
Authors: Michel Sadelain, Renier J. Brentjens, Isabelle Rivière - Cancer Discovery 2013 cited by 1,498
- A Phase I Trial of Regional Mesothelin-Targeted CAR T-cell Therapy in Patients with Malignant Pleural Disease, in Combination with the Anti–PD-1 Agent Pembrolizumab
Authors: Prasad S. Adusumilli, Marjorie G. Zauderer, Isabelle Rivière, Stephen B. Solomon, Valerie W. Rusch, Roisin E. O’Cearbhaill, Amy Zhu, Waseem Cheema, Navin K. Chintala, Elizabeth Halton, John Pineda, Rocío Pérez-Johnston, Kay See Tan, Bobby Daly, Jose A. Araujo Filho, Daniel Ngai, Erin McGee, A. Vincent, Claudia Diamonte, Jennifer L. Sauter, Shanu Modi, Devanjan Sikder, Brigitte Sénéchal, Xiuyan Wang, William D. Travis, Mithat Gönen, Charles M. Rudin, Renier J. Brentjens, David R. Jones, Michel Sadelain - Cancer Discovery 2021 cited by 560
- Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
Authors: Stuart M. Chambers, Christopher A. Fasano, Eirini P. Papapetrou, Mark Tomishima, Michel Sadelain, Lorenz Studer - Nature Biotechnology 2009 cited by 3,674
- Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia
Authors: Marco L. Davila, Isabelle Rivière, Xiuyan Wang, Shirley Bartido, Jae H. Park, Kevin J. Curran, Stephen S. Chung, Jolanta Stefanski, Oriana Bórquez-Ojeda, Malgorzata Olszewska, Jinrong Qu, Teresa Wasielewska, Qing He, Mitsú J. Fink, Himaly Shinglot, Maher Youssif, Mark Satter, Yongzeng Wang, James Hosey, Hilda Quintanilla, Elizabeth Halton, Yvette Bernal, Diana Bouhassira, Maria E. Arcila, Mithat Gönen, Gail J. Roboz, P. Maslak, Dan Douer, Mark G. Frattini, Sergio Giralt, Michel Sadelain, Renier J. Brentjens - Science Translational Medicine 2014 cited by 2,497
- CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape
Authors: Mohamad Hamieh, Anton Dobrin, Annalisa Cabriolu, Sjoukje J. C. van der Stegen, Theodoros Giavridis, Jorge Mansilla‐Soto, Justin Eyquem, Zeguo Zhao, Benjamin M. Whitlock, Matthew M. Miele, Zhuoning Li, Kristen Cunanan, Morgan Huse, Ronald C. Hendrickson, Xiuyan Wang, Isabelle Rivière, Michel Sadelain - Nature 2019 cited by 665
- Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia
Authors: Bianca Santomasso, Jae H. Park, Darin Salloum, Isabelle Rivière, Jessica Flynn, Elena Mead, Elizabeth Halton, Xiuyan Wang, Brigitte Sénéchal, Terence J. Purdon, Justin R. Cross, Hui Liu, Behroze Vachha, Xi Chen, Lisa M. DeAngelis, Daniel Li, Yvette Bernal, Mithat Gönen, Hans-Guido Wendel, Michel Sadelain, Renier J. Brentjens - Cancer Discovery 2018 cited by 924
- Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition
Authors: Leonid Cherkassky, Aurore Morello, Jonathan Villena‐Vargas, Yang Feng, Dimiter S. Dimitrov, David R. Jones, Michel Sadelain, Prasad S. Adusumilli - Journal of Clinical Investigation 2016 cited by 1,063
- Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells
Authors: Zeguo Zhao, Maud Condomines, Sjoukje J. C. van der Stegen, Fabiana Perna, Christopher C. Kloss, Gertrude Gunset, Jason Plotkin, Michel Sadelain - Cancer Cell 2015 cited by 838
- CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia
Authors: Renier J. Brentjens, Marco L. Davila, Isabelle Rivière, Jae H. Park, Xiuyan Wang, Lindsay G. Cowell, Shirley Bartido, Jolanta Stefanski, Clare Taylor, Malgorzata Olszewska, Oriana Bórquez-Ojeda, Jinrong Qu, Teresa Wasielewska, Qing He, Yvette Bernal, Ivelise Rijo, Cyrus V. Hedvat, Rachel Kobos, Kevin J. Curran, Peter G. Steinherz, Joseph G. Jurcic, Todd Rosenblat, P. Maslak, Mark G. Frattini, Michel Sadelain - Science Translational Medicine 2013 cited by 2,077
- Therapeutic T cell engineering
Authors: Michel Sadelain, Isabelle Rivière, Stanley R. Riddell - Nature 2017 cited by 898
- Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency
Authors: Judith Feucht, Jie Sun, Justin Eyquem, Yu-Jui Ho, Zeguo Zhao, Josef Leibold, Anton Dobrin, Annalisa Cabriolu, Mohamad Hamieh, Michel Sadelain - Nature Medicine 2018 cited by 543
- Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy
Authors: Melody Smith, Anqi Dai, Guido Ghilardi, Kimberly V. Amelsberg, Sean M. Devlin, Raymone Pajarillo, John Slingerland, Silvia Beghi, Pamela S. Herrera, Paul A. Giardina, Annelie Clurman, Emmanuel Agyemang Dwomoh, Gabriel K. Armijo, Antonio L. C. Gomes, Eric R. Littmann, Jonas Schlüter, Emily Fontana, Ying Taur, Jae H. Park, Maria Lia Palomba, Elizabeth Halton, Josel D. Ruiz, Tania Jain, Martina Pennisi, Aishat Olaide Afuye, Miguel‐Angel Perales, Craig W. Freyer, Alfred L. Garfall, Shannon Gier, Sunita D. Nasta, Daniel J. Landsburg, James N. Gerson, Jakub Svoboda, Justin R. Cross, Elise A. Chong, Sergio Giralt, Saar Gill, Isabelle Rivière, David L. Porter, Stephen J. Schuster, Michel Sadelain, Noelle V. Frey, Renier J. Brentjens, Carl H. June, Eric G. Pamer, Jonathan U. Peled, Andrea Facciabene, Marcel R.M. van den Brink, Marco Ruella - Nature Medicine 2022 cited by 309
- Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ /CD28 receptor
Authors: John Maher, Renier J. Brentjens, Gertrude Gunset, Isabelle Rivière, Michel Sadelain - Nature Biotechnology 2002 cited by 1,019
- Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction
Authors: Corina Amor, Inés Fernández-Maestre, Saria Chowdhury, Yu-Jui Ho, Sandeep Nadella, Courtenay Graham, Sebastian E. Carrasco, Emmanuella Nnuji-John, Judith Feucht, Clemens Hinterleitner, Valentin J.A. Barthet, Jacob A. Boyer, Riccardo Mezzadra, Matthew Wereski, David A. Tuveson, Ross L. Levine, Lee W. Jones, Michel Sadelain, Scott W. Lowe - Nature Aging 2024 cited by 184
- The tyrosine kinase inhibitor dasatinib acts as a pharmacologic on/off switch for CAR T cells
Authors: Katrin Mestermann, Theodoros Giavridis, Justus Weber, Julian Rydzek, Silke Frenz, Thomas Nerreter, Andreas Mades, Michel Sadelain, Hermann Einsele, Michael Hudecek - Science Translational Medicine 2019 cited by 503
- PD-1– and CTLA-4–Based Inhibitory Chimeric Antigen Receptors (iCARs) Divert Off-Target Immunotherapy Responses
Authors: V D Fedorov, Maria Themeli, Michel Sadelain - Science Translational Medicine 2013 cited by 731
