J. Keith Joung
Active 1994–2025
- 117
- Papers
- 55,741
- Citations
- 91
- h-index
- 116
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology76.1%
- Medicine11.1%
- Neuroscience6.1%
- Agricultural and Biological Sciences2.1%
- Immunology and Microbiology1.8%
- Engineering0.7%
- Other2.1%
Topics
- CRISPR and Genetic Engineering19.8%
- RNA and protein synthesis mechanisms4.6%
- Advanced biosensing and bioanalysis techniques4%
- RNA Interference and Gene Delivery3.7%
- Virus-based gene therapy research3.2%
- Pluripotent Stem Cells Research2.6%
- Other62.1%
Coauthors
- Jeffry D. Sander29
- Deepak Reyon28
- Morgan L. Maeder25
- Shengdar Q. Tsai24
- Benjamin P. Kleinstiver19
- Martin J. Aryee19
- Daniel F. Voytas14
- Luca Pinello13
- Cyd Khayter11
- Kendell Clement11
- Drena Dobbs9
- Jing-Ruey Joanna Yeh9
- Jonathan Y. Hsu9
- Karl Petri9
- Nathalie T. Nguyen9
- Stacey Thibodeau-Beganny9
- David R. Liu8
- Julian Grünewald8
- Mathew J. Goodwin8
- Randall T. Peterson8
- Sara P. Garcia8
- Vikram Pattanayak8
- Yanfang Fu8
- Ved V. Topkar7
All papers
- CRISPResso2 provides accurate and rapid genome editing sequence analysis
Authors: Kendell Clement, Holly A. Rees, Matthew C. Canver, Jason M. Gehrke, Rick Farouni, Jonathan Y. Hsu, Mitchel A. Cole, David R. Liu, J. Keith Joung, Daniel E. Bauer, Luca Pinello - Nature Biotechnology 2019 cited by 1,819
- High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
Authors: Benjamin P. Kleinstiver, Vikram Pattanayak, Michelle S. Prew, Shengdar Q. Tsai, Nathalie T. Nguyen, Zongli Zheng, J. Keith Joung - Nature 2016 cited by 2,738
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
Authors: Shengdar Q. Tsai, Zongli Zheng, Nathalie T. Nguyen, Matthew Liebers, Ved V. Topkar, Vishal Thapar, Nicolas Wyvekens, Cyd Khayter, A. John Iafrate, Long P. Le, Martin J. Aryee, J. Keith Joung - Nature Biotechnology 2014 cited by 2,307
- Gene therapy comes of age
Authors: Cynthia E. Dunbar, Katherine A. High, J. Keith Joung, Donald B. Kohn, Keiya Ozawa, Michel Sadelain - Science 2018 cited by 1,378
- High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
Authors: Yanfang Fu, Jennifer A Foden, Cyd Khayter, Morgan L. Maeder, Deepak Reyon, J. Keith Joung, Jeffry D. Sander - Nature Biotechnology 2013 cited by 3,327
- Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways
Authors: Won‐Suk Chung, Laura Clarke, Gordon Wang, Benjamin K. Stafford, Alexander Sher, Chandrani Chakraborty, J. Keith Joung, Lynette C. Foo, Andrew Thompson, Chinfei Chen, Stephen J Smith, Ben A. Barres - Nature 2013 cited by 1,420
- Engineered CRISPR-Cas9 nucleases with altered PAM specificities
Authors: Benjamin P. Kleinstiver, Michelle S. Prew, Shengdar Q. Tsai, Ved V. Topkar, Nathalie T. Nguyen, Zongli Zheng, Andrew P. W. Gonzales, Zhuyun Li, Randall T. Peterson, Jing-Ruey Joanna Yeh, Martin J. Aryee, J. Keith Joung - Nature 2015 cited by 1,686
- CRISPR-Cas systems for editing, regulating and targeting genomes
Authors: Jeffry D. Sander, J. Keith Joung - Nature Biotechnology 2014 cited by 3,178
- Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
Authors: Janice S. Chen, Yavuz S. Dagdas, Benjamin P. Kleinstiver, Moira M. Welch, Alexander A. Sousa, Lucas B. Harrington, Samuel H. Sternberg, J. Keith Joung, Ahmet Yıldız, Jennifer A. Doudna - Nature 2017 cited by 1,237
- Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo
Authors: John A. Zuris, David B. Thompson, Yilai Shu, John P. Guilinger, Jeffrey L. Bessen, Johnny H. Hu, Morgan L. Maeder, J. Keith Joung, Zheng‐Yi Chen, David R. Liu - Nature Biotechnology 2014 cited by 1,471
- CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells
Authors: Ibrahim Cagri Kurt, Ronghao Zhou, Sowmya Iyer, Sara P. Garcia, Bret R. Miller, Lukas M. Langner, Julian Grünewald, J. Keith Joung - Nature Biotechnology 2020 cited by 579
- Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing
Authors: Benjamin P. Kleinstiver, Alexander A. Sousa, Russell T. Walton, Y. Esther Tak, Jonathan Y. Hsu, Kendell Clement, Moira M. Welch, Joy E. Horng, Jose Malagon-Lopez, Irene Scarfò, Marcela V. Maus, Luca Pinello, Martin J. Aryee, J. Keith Joung - Nature Biotechnology 2019 cited by 724
- CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets
Authors: Shengdar Q. Tsai, Nathalie T. Nguyen, Jose Malagon-Lopez, Ved V. Topkar, Martin J. Aryee, J. Keith Joung - Nature Methods 2017 cited by 834
- Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
Authors: Julian Grünewald, Ronghao Zhou, Sara P. Garcia, Sowmya Iyer, Caleb A. Lareau, Martin J. Aryee, J. Keith Joung - Nature 2019 cited by 692
- Efficient genome editing in zebrafish using a CRISPR-Cas system
Authors: Woong Y. Hwang, Yanfang Fu, Deepak Reyon, Morgan L. Maeder, Shengdar Q. Tsai, Jeffry D. Sander, Randall T. Peterson, J-R Joanna Yeh, J. Keith Joung - Nature Biotechnology 2013 cited by 3,003
- TALENs: a widely applicable technology for targeted genome editing
Authors: J. Keith Joung, Jeffry D. Sander - Nature Reviews Molecular Cell Biology 2012 cited by 1,635
- Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
Authors: Yanfang Fu, Jeffry D. Sander, Deepak Reyon, Vincent Cascio, J. Keith Joung - Nature Biotechnology 2014 cited by 2,023
- High levels of AAV vector integration into CRISPR-induced DNA breaks
Authors: Killian S. Hanlon, Benjamin P. Kleinstiver, Sara P. Garcia, Mikołaj Piotr Zaborowski, Adrienn Volak, Stefan E. Spirig, Alissa Muller, Alexander A. Sousa, Shengdar Q. Tsai, Niclas E. Bengtsson, Camilla Lööv, Martin Ingelsson, Jeffrey S. Chamberlain, David P. Corey, Martin J. Aryee, J. Keith Joung, Xandra O. Breakefield, Casey A. Maguire, Bence György - Nature Communications 2019 cited by 432
- CRISPR RNA–guided activation of endogenous human genes
Authors: Morgan L. Maeder, Samantha J Linder, Vincent Cascio, Yanfang Fu, Quan Van Ho, J. Keith Joung - Nature Methods 2013 cited by 1,269
- Multidimensional control of therapeutic human cell function with synthetic gene circuits
Authors: Hui-Shan Li, Divya V. Israni, Keith A. Gagnon, Kok Ann Gan, Michael H. Raymond, Jeffry D. Sander, Kole T. Roybal, J. Keith Joung, Wilson W. Wong, Ahmad S. Khalil - Science 2022 cited by 153
- An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities
Authors: Jason M. Gehrke, Oliver Cervantes, Kendell Clement, Yuxuan Wu, Jing Zeng, Daniel E. Bauer, Luca Pinello, J. Keith Joung - Nature Biotechnology 2018 cited by 451
- Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells
Authors: Benjamin P. Kleinstiver, Shengdar Q. Tsai, Michelle S. Prew, Nathalie T. Nguyen, Moira M. Welch, Jose M. Lopez, Zachary R. McCaw, Martin J. Aryee, J. Keith Joung - Nature Biotechnology 2016 cited by 714
- CRISPR DNA base editors with reduced RNA off-target and self-editing activities
Authors: Julian Grünewald, Ronghao Zhou, Sowmya Iyer, Caleb A. Lareau, Sara P. Garcia, Martin J. Aryee, J. Keith Joung - Nature Biotechnology 2019 cited by 345
- Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition
Authors: Benjamin P. Kleinstiver, Michelle S. Prew, Shengdar Q. Tsai, Nathalie T. Nguyen, Ved V. Topkar, Zongli Zheng, J. Keith Joung - Nature Biotechnology 2015 cited by 630
