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Paul Säftig

Active 1993–2025

206
Papers
49,164
Citations
120
h-index
204
i10-index

Citations

Citations per year for Paul Säftig1971: 1 citations1984: 1 citations1992: 1 citations1994: 2 citations1995: 6 citations1996: 9 citations1997: 12 citations1998: 42 citations1999: 140 citations2000: 251 citations2001: 281 citations2002: 319 citations2003: 330 citations2004: 342 citations2005: 446 citations2006: 520 citations2007: 528 citations2008: 819 citations2009: 671 citations2010: 724 citations2011: 783 citations2012: 741 citations2013: 739 citations2014: 649 citations2015: 627 citations2016: 650 citations2017: 674 citations2018: 506 citations2019: 1,577 citations2020: 1,758 citations2021: 1,589 citations2022: 1,318 citations2023: 946 citations2024: 1,355 citations2025: 631 citations2026: 13 citations1972–1983: no citations, so these years are not shown1985–1991: no citations, so these years are not shown1993: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 5,988 citing papers, 27.1% of this breakdownChina: 2,279 citing papers, 10.3% of this breakdownGermany: 1,935 citing papers, 8.7% of this breakdownUnited Kingdom: 1,410 citing papers, 6.4% of this breakdownFrance: 957 citing papers, 4.3% of this breakdownJapan: 936 citing papers, 4.2% of this breakdownItaly: 873 citing papers, 4% of this breakdownCanada: 710 citing papers, 3.2% of this breakdownAustralia: 536 citing papers, 2.4% of this breakdownNetherlands: 518 citing papers, 2.3% of this breakdownBelgium: 470 citing papers, 2.1% of this breakdownSpain: 428 citing papers, 1.9% of this breakdown
0%27.1%Other 23.1%

Institutions

Fields

  • Medicine48.9%
  • Biochemistry, Genetics and Molecular Biology33.6%
  • Immunology and Microbiology9%
  • Neuroscience4.7%
  • Engineering0.9%
  • Materials Science0.5%
  • Other2.4%

Topics

  • Autophagy in Disease and Therapy5%
  • Alzheimer's disease research and treatments4.8%
  • Cellular transport and secretion3%
  • Lysosomal Storage Disorders Research2.3%
  • Calcium signaling and nucleotide metabolism1.9%
  • Immunotherapy and Immune Responses1.9%
  • Other81.1%

Coauthors

All papers

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  1. Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

    Authors: Lionel Apétoh, François Ghiringhelli, Antoine Tesnière, Michel Obéid, Carla Ortiz, Alfredo Criollo, Grégoire Mignot, Maria Chiara Maiuri, Evelyn Ullrich, Patrick Saulnier, Huan Yang, Sebastián Amigorena, Bernard Ryffel, Franck J. Barrat, Paul Säftig, Françis Lévi, Rosette Lidereau, Catherine Noguès, Jean‐Paul Mira, Agnès Chompret, V. Joulin, Françoise Clavel‐Chapelon, Jean Bourhis, Fabrice André, Suzette Delaloge, Thomas Tursz, Guido Kroemer, Laurence Zitvogel - Nature Medicine 2007 cited by 2,969

  2. Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

    Authors: Paul Säftig, Judith Klumperman - Nature Reviews Molecular Cell Biology 2009 cited by 1,699

  3. The Tetraspanin CD63 Regulates ESCRT-Independent and -Dependent Endosomal Sorting during Melanogenesis

    Authors: Guillaume van Niel, Stéphanie Charrin, Sabrina Simoes, Maryse Romao, Leïla Rochin, Paul Säftig, Michael S. Marks, Eric Rubinstein, Graça Raposo - Developmental Cell 2011 cited by 916

  4. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

    Authors: Bart De Strooper, Paul Säftig, Katleen Craessaerts, Hugo Vanderstichele, Gundula Guhde, Wim Annaert, Kurt Von Figura, F. Van Leuven - Nature 1998 cited by 1,824

  5. Notch–RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization

    Authors: Haixia Xu, Jimmy Zhu, Sinéad M. Smith, Julia Foldi, Baohong Zhao, Allen Chung, Hasina H. Outtz, Jan Kitajewski, Chao Shi, Silvio Weber, Paul Säftig, Yue‐Ming Li, Keiko Ozato, Carl Blobel, Lionel B. Ivashkiv, Xiaoyu Hu - Nature Immunology 2012 cited by 438

  6. A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

    Authors: Bart De Strooper, Wim Annaert, Philippe Cupers, Paul Säftig, Katleen Craessaerts, Jeff S. Mumm, Eric H. Schroeter, Vincent Schrijvers, Michael S. Wolfe, William J. Ray, Alison Goate, Raphael Kopan - Nature 1999 cited by 2,108

  7. LIMP-2 Is a Receptor for Lysosomal Mannose-6-Phosphate-Independent Targeting of β-Glucocerebrosidase

    Authors: David Reczek, Michael Schwake, J Schröder, Heather Hughes, Judith Blanz, Xiaoying Jin, William Brondyk, Scott Van Patten, Tim Edmunds, Paul Säftig - Cell 2007 cited by 528

  8. Cholesterol Handling in Lysosomes and Beyond

    Authors: Ying Meng, Saskia Heybrock, Dante Neculai, Paul Säftig - Trends in Cell Biology 2020 cited by 193

  9. The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion

    Authors: Christian Hundhausen, Dominika Misztela, Theo A. Berkhout, Neil Broadway, Paul Säftig, Karina Reiß, Dieter Hartmann, Falk Fahrenholz, Rolf Postina, Vance B. Matthews, Karl‐Josef Kallen, Stefan Rose‐John, Andreas Ludwig - Blood 2003 cited by 721

  10. At the acidic edge: emerging functions for lysosomal membrane proteins

    Authors: Eeva‐Liisa Eskelinen, Yoshitaka Tanaka, Paul Säftig - Trends in Cell Biology 2003 cited by 656

  11. Metalloproteases regulate T‐cell proliferation and effector function via LAG‐3

    Authors: Nianyu Li, Yao Wang, Karen Forbes, Kate M. Vignali, Bret S.E. Heale, Paul Säftig, Dieter Hartmann, Roy A. Black, John J. Rossi, Carl Blobel, Peter J. Dempsey, Creg J. Workman, Dario A.A. Vignali - The EMBO Journal 2007 cited by 283

  12. Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice

    Authors: Yoshitaka Tanaka, Gundula Guhde, Anke Suter, Eeva‐Liisa Eskelinen, Dieter Hartmann, Renate Lüllmann‐Rauch, Paul M.L. Janssen, Judith Blanz, Kurt Von Figura, Paul Säftig - Nature 2000 cited by 905

  13. Role for Rab7 in maturation of late autophagic vacuoles

    Authors: Stefanie Jäger, Cecilia Bucci, Isei Tanida, Takashi Ueno, Eiki Kominami, Paul Säftig, Eeva‐Liisa Eskelinen - Journal of Cell Science 2004 cited by 874

  14. Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway

    Authors: Haiyan Liu, Ali Javaheri, Rebecca J. Godar, John T. Murphy, Xiucui Ma, Nidhi Rohatgi, Jana Mahadevan, Krzysztof Hyrc, Paul Säftig, Connie A. Marshall, Michael L. McDaniel, Marı́a S. Remedi, Babak Razani, Fumihiko Urano, Abhinav Diwan - Autophagy 2017 cited by 189

  15. LAMP proteins are required for fusion of lysosomes with phagosomes

    Authors: Kassidy K. Huynh, Eeva‐Liisa Eskelinen, Cameron C. Scott, Anatoly Malevanets, Paul Säftig, Sergio Grinstein - The EMBO Journal 2007 cited by 685

  16. Lysosomal storage disorders – challenges, concepts and avenues for therapy: beyond rare diseases

    Authors: André R. A. Marques, Paul Säftig - Journal of Cell Science 2019 cited by 226

  17. Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export

    Authors: Saskia Heybrock, Kristiina Kanerva, Ying Meng, Chris Ing, Anna Liang, Zi-Jian Xiong, Xialian Weng, Young Ah Kim, Richard F. Collins, William S. Trimble, Régis Pomès, Gilbert G. Privé, Wim Annaert, Michael Schwake, Jöerg Heeren, Renate Lüllmann‐Rauch, Sergio Grinstein, Elina Ikonen, Paul Säftig, Dante Neculai - Nature Communications 2019 cited by 162

  18. Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36

    Authors: Dante Neculai, Michael Schwake, Mani Ravichandran, Friederike Zunke, Richard F. Collins, Judith Peters, M. Neculai, Jonathan Plumb, P. Loppnau, J.C. Pizarro, Alma Seitova, William S. Trimble, Paul Säftig, Sergio Grinstein, Sirano Dhe‐Paganon - Nature 2013 cited by 287

  19. Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance

    Authors: Verena Arndt, Nikolaus Dick, Riga Tawo, Michael Dreiseidler, Daniela Wenzel, Michael Hesse, Dieter O. Fürst, Paul Säftig, Robert Saint, Bernd K. Fleischmann, Michael Hoch, Jörg Höhfeld - Current Biology 2010 cited by 567

  20. Lysosomal Membrane Proteins and Their Central Role in Physiology

    Authors: Michael Schwake, Bernd Schröder, Paul Säftig - Traffic 2013 cited by 259

  21. Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models

    Authors: Susy Prieto Huarcaya, Alice Drobny, André R. A. Marques, Alessandro Di Spiezio, Jan Philipp Dobert, Denise Balta, Christian Werner, Tania Rizo, Lisa Gallwitz, Simon Bub, Iva Stojkovska, Nandkishore R. Belur, J. Fogh, Joseph R. Mazzulli, Wei Xiang, Amitkumar Fulzele, Mario Dejung, Markus Sauer, Beate Winner, Stefan Rose‐John, Philipp Arnold, Paul Säftig, Friederike Zunke - Autophagy 2022 cited by 84

  22. Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice

    Authors: Barbara Spix, Elisabeth Butz, Cheng‐Chang Chen, Anna Scotto Rosato, Rachel Tang, Aicha Jeridi, Veronika Kudrina, Eva Plesch, Philipp Wartenberg, Elisabeth Arlt, Daria Briukhovetska, Meshal Ansari, Gizem Günes Günsel, Thomas M. Conlon, Amanda Wyatt, Sandra Wetzel, Daniel Teupser, Lesca M. Holdt, Fabien Ectors, Ingrid Boekhoff, Ulrich Boehm, Jaime Garcı́a-Añoveros, Paul Säftig, Martin Giera, Sebastian Kobold, Herbert B. Schiller, Susanna Zierler, Thomas Gudermann, Christian Wahl‐Schott, Franz Bracher, Ali Önder Yildirim, Martin Biel, Christian Grimm - Nature Communications 2022 cited by 71

  23. Lysosome-targeted multifunctional lipid probes reveal the sterol transporter NPC1 as a sphingosine interactor

    Authors: Janathan Altuzar, Judith Notbohm, Frank Stein, Per Haberkant, Pia Hempelmann, Saskia Heybrock, Jutta Worsch, Paul Säftig, Doris Höglinger - National Academy of Sciences, Proceedings of the National Academy of Sciences 2023 cited by 59

  24. How Lysosomes Sense, Integrate, and Cope with Stress

    Authors: Paul Säftig, Rosa Puertollano - Trends in Biochemical Sciences 2020 cited by 138