Elias S.J. Arnér
Active 1992–2025
- Also published as
- Elias S J Arnér
- 106
- Papers
- 20,912
- Citations
- 72
- h-index
- 103
- i10-index
Citations
Citation sources
Countries
Institutions
- Karolinska Institutet1.6%
- Harvard University0.7%
- Centre National de la Recherche Scientifique0.7%
- Inserm0.5%
- Central South University0.5%
- Heidelberg University0.4%
- Other95.6%
Fields
- Biochemistry, Genetics and Molecular Biology40.5%
- Medicine30.8%
- Nursing11.6%
- Immunology and Microbiology4%
- Chemistry2.7%
- Agricultural and Biological Sciences2.5%
- Other7.9%
Topics
- Redox biology and oxidative stress7.5%
- Ferroptosis and cancer prognosis5.5%
- Selenium in Biological Systems4.9%
- Sulfur Compounds in Biology3.6%
- Trace Elements in Health3%
- Genomics, phytochemicals, and oxidative stress2.9%
- Other72.6%
Coauthors
- Qing Cheng26
- Arne Holmgren17
- Edward E. Schmidt12
- Markus Dagnell8
- Sofi Eriksson7
- Justin R. Prigge6
- Karoline Scholzen6
- Radosveta Gencheva6
- Galina Selivanova5
- Linda Johansson5
- Roman A. Zubarev5
- Stefanie Prast‐Nielsen5
- Amir Ata Saei4
- Antonio Miranda‐Vizuete4
- Belén Espinosa4
- David L. Williams4
- Dorian M. Cheff4
- Irina Pader4
- Jan G. Felber4
- Jianqiang Xu4
- Katarina Johansson4
- Liangwei Zhong4
- Lukas Zeisel4
- Matthew D. Hall4
All papers
- Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis
Authors: Irina Ingold, Carsten Berndt, Sabine Schmitt, Sebastian Doll, Gereon Poschmann, Katalin Buday, Antonella Roveri, Xiaoxiao Peng, Florêncio Porto Freitas, Tobias Seibt, Lisa Mehr, Michaela Aichler, Axel Walch, Daniel Lamp, Martin Jastroch, Sayuri Miyamoto, Wolfgang Wurst, Fulvio Ursini, Elias S.J. Arnér, Noelia Fradejas‐Villar, Ulrich Schweizer, Hans Zischka, José Pedro Friedmann Angeli, Marcus Conrad - Cell 2017 cited by 1,677
- The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1
Authors: Dorian M. Cheff, Chuying Huang, Karoline Scholzen, Radosveta Gencheva, Michael Ronzetti, Qing Cheng, Matthew D. Hall, Elias S.J. Arnér - Redox Biology 2023 cited by 245
- Physiological functions of thioredoxin and thioredoxin reductase
Authors: Elias S.J. Arnér, Arne Holmgren - European Journal of Biochemistry 2000 cited by 2,527
- Reactive oxygen species, antioxidants, and the mammalian thioredoxin system1 1This review is based on the licentiate thesis “Thioredoxin reductase—interactions with the redox active compounds 1-chloro-2,4-dinitrobenzene and lipoic acid” by Jonas Nordberg, 2001, Karolinska Institute, Stockholm, ISBN 91-631-1064-4.
Authors: Jonas Nordberg, Elias S.J. Arnér - Free Radical Biology and Medicine 2001 cited by 2,654
- Control of protein function through oxidation and reduction of persulfidated states
Authors: Éva Dóka, Tomoaki Ida, Markus Dagnell, Yumi Abiko, Nho Cong Luong, Noémi Balog, Tsuyoshi Takata, Belén Espinosa, Akira Nishimura, Qing Cheng, Yosuke Funato, Hiroaki Miki, Jon M. Fukuto, Justin R. Prigge, Edward E. Schmidt, Elias S.J. Arnér, Yoshito Kumagai, Takaaki Akaike, Péter Nagy - Science Advances 2020 cited by 210
- Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications
Authors: Xin Gen Lei, Jian‐Hong Zhu, Wen-Hsing Cheng, Yongping Bao, Ye-Shih Ho, Amit R. Reddi, Arne Holmgren, Elias S.J. Arnér - Physiological Reviews 2015 cited by 426
- Thioredoxin Reductase Inhibition for Cancer Therapy
Authors: Radosveta Gencheva, Elias S.J. Arnér - The Annual Review of Pharmacology and Toxicology 2021 cited by 167
- A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems
Authors: Éva Dóka, Irina Pader, Adrienn Bíró, Katarina Johansson, Qing Cheng, Krisztina Ballagó, Justin R. Prigge, Daniel Pastor‐Flores, Tobias P. Dick, Edward E. Schmidt, Elias S.J. Arnér, Péter Nagy - Science Advances 2016 cited by 323
- Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy
Authors: William C. Stafford, Xiaoxiao Peng, Maria Hägg Olofsson, Xiaonan Zhang, Diane K. Luci, Frank Leigh Lu, Qing Cheng, L. Tresaugues, Thomas S. Dexheimer, Nathan P. Coussens, Martin Augsten, Hanna-Stina Martinsson Ahlzén, Owe Orwar, Arne Östman, Sharon Stone‐Elander, David J. Maloney, Ajit Jadhav, Anton Simeonov, Stig Linder, Elias S.J. Arnér - Science Translational Medicine 2018 cited by 243
- Targeting of Nrf2 improves antitumoral responses by human NK cells, TIL and CAR T cells during oxidative stress
Authors: Stefanie Renken, Takahiro Nakajima, Isabelle Magalhaes, Jonas Mattsson, Andreas Lundqvist, Elias S.J. Arnér, Rolf Kiessling, Stina L. Wickström - Journal for ImmunoTherapy of Cancer 2022 cited by 62
- The thioredoxin system in cancer
Authors: Elias S.J. Arnér, Arne Holmgren - Seminars in Cancer Biology 2006 cited by 579
- TrxR1 as a Potent Regulator of the Nrf2-Keap1 Response System
Authors: Marcus Cebula, Edward E. Schmidt, Elias S.J. Arnér - Antioxidants and Redox Signaling 2015 cited by 250
- Focus on mammalian thioredoxin reductases — Important selenoproteins with versatile functions
Authors: Elias S.J. Arnér - Biochimica et Biophysica Acta (BBA) - General Subjects 2009 cited by 664
- Selenoproteins—What unique properties can arise with selenocysteine in place of cysteine?
Authors: Elias S.J. Arnér - Experimental Cell Research 2010 cited by 313
- Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase
Authors: Irina Pader, Rajib Sengupta, Marcus Cebula, Jianqiang Xu, Jon O. Lundberg, Arne Holmgren, Katarina Johansson, Elias S.J. Arnér - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 166
- Selenoprotein Gene Nomenclature
Authors: Vadim N. Gladyshev, Elias S.J. Arnér, Marla J. Berry, Regina Brigelius‐Flohé, Elspeth A. Bruford, Raymond F. Burk, Bradley A. Carlson, Sergi Castellano, Laurent Chavatte, Marcus Conrad, Paul R. Copeland, Alan M. Diamond, Donna M. Driscoll, Ana Ferreiro, Leopold Flohé, Fiona R. Green, Roderic Guigó, Diane E. Handy, Dolph L. Hatfield, John E. Hesketh, Peter R. Hoffmann, Arne Holmgren, Robert J. Hondal, Michael Howard, Kaixun Huang, Hwa‐Young Kim, Ick Young Kim, Josef Köhrle, Alain Krol, Gregory V. Kryukov, Byeong Jae Lee, Byung Cheon Lee, Xin Gen Lei, Qiong Liu, Alain Lescure, Alexei Lobanov, Joseph Loscalzo, Matilde Maiorino, Marco Mariotti, K. Sandeep Prabhu, Margaret P. Rayman, Sharon Rozovsky, Gustavo Salinas, Edward E. Schmidt, Lutz Schomburg, Ulrich Schweizer, Miljan Simonović, Roger A. Sunde, Petra A. Tsuji, Susan Tweedie, Fulvio Ursini, P.D. Whanger, Yan Zhang - Journal of Biological Chemistry 2016 cited by 276
- Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug
Authors: Xiaonan Zhang, Karthik Selvaraju, Amir Ata Saei, Pádraig D’Arcy, Roman A. Zubarev, Elias S.J. Arnér, Stig Linder - Biochimie 2019 cited by 168
- Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX4
Authors: Dorian M. Cheff, Qing Cheng, Hui Guo, Jameson Travers, Carleen Klumpp‐Thomas, Min Shen, Elias S.J. Arnér, Matthew D. Hall - Redox Biology 2023 cited by 37
- NADPH-dependent and -independent disulfide reductase systems
Authors: Colin G. Miller, Arne Holmgren, Elias S.J. Arnér, Edward E. Schmidt - Free Radical Biology and Medicine 2018 cited by 111
- TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy
Authors: Michael McLoughlin, David J. Orlicky, Justin R. Prigge, Pushya Krishna, Emily A. Talago, Ian Cavigli, Sofi Eriksson, Colin G. Miller, Jean A. Kundert, Volkan I. Sayin, Rachel A. Sabol, Joshua Heinemann, Luke O. Brandenberger, Sonya V. Iverson, Brian Bothner, Thales Papagiannakopoulos, Colin T. Shearn, Elias S.J. Arnér, Edward E. Schmidt - National Academy of Sciences, Proceedings of the National Academy of Sciences 2019 cited by 102
- Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides
Authors: Maria Schwarz, Alina Löser, Qing Cheng, Mareike Wichmann-Costaganna, Patrick Schädel, Oliver Werz, Elias S.J. Arnér, Anna P. Kipp - Redox Biology 2023 cited by 54
- Structure and mechanism of mammalian thioredoxin reductase: The active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence
Authors: Liangwei Zhong, Elias S.J. Arnér, Arne Holmgren - National Academy of Sciences, Proceedings of the National Academy of Sciences 2000 cited by 517
- Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades
Authors: Markus Dagnell, Qing Cheng, Syed Husain Mustafa Rizvi, Paul E. Pace, Benoît Boivin, Christine C. Winterbourn, Elias S.J. Arnér - Journal of Biological Chemistry 2019 cited by 68
- Thioredoxin reductase selenoproteins from different organisms as potential drug targets for treatment of human diseases
Authors: Radosveta Gencheva, Qing Cheng, Elias S.J. Arnér - Free Radical Biology and Medicine 2022 cited by 44
