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Ettore Appella

Active 1961–2025

242
Papers
60,836
Citations
133
h-index
242
i10-index

Citations

Citations per year for Ettore Appella1967: 20 citations1968: 14 citations1969: 17 citations1970: 15 citations1971: 9 citations1972: 5 citations1973: 6 citations1974: 5 citations1975: 8 citations1976: 2 citations1977: 2 citations1978: 16 citations1979: 19 citations1980: 22 citations1981: 34 citations1982: 44 citations1983: 42 citations1984: 80 citations1985: 60 citations1986: 53 citations1987: 78 citations1988: 119 citations1989: 237 citations1990: 296 citations1991: 385 citations1992: 474 citations1993: 546 citations1994: 595 citations1995: 606 citations1996: 601 citations1997: 580 citations1998: 605 citations1999: 799 citations2000: 757 citations2001: 762 citations2002: 789 citations2003: 683 citations2004: 783 citations2005: 641 citations2006: 602 citations2007: 635 citations2008: 559 citations2009: 566 citations2010: 585 citations2011: 430 citations2012: 434 citations2013: 392 citations2014: 412 citations2015: 313 citations2016: 280 citations2017: 243 citations2018: 209 citations2019: 772 citations2020: 790 citations2021: 701 citations2022: 571 citations2023: 389 citations2024: 511 citations2025: 224 citations2026: 5 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 7,872 citing papers, 39.4% of this breakdownChina: 1,332 citing papers, 6.7% of this breakdownUnited Kingdom: 1,320 citing papers, 6.6% of this breakdownGermany: 1,048 citing papers, 5.3% of this breakdownJapan: 992 citing papers, 5% of this breakdownFrance: 757 citing papers, 3.8% of this breakdownItaly: 742 citing papers, 3.7% of this breakdownCanada: 648 citing papers, 3.2% of this breakdownAustralia: 453 citing papers, 2.3% of this breakdownSwitzerland: 372 citing papers, 1.9% of this breakdownNetherlands: 346 citing papers, 1.7% of this breakdownIndia: 323 citing papers, 1.6% of this breakdown
0%39.4%Other 18.8%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology41.9%
  • Medicine36.4%
  • Immunology and Microbiology16.1%
  • Neuroscience1.3%
  • Chemistry1.3%
  • Agricultural and Biological Sciences0.9%
  • Other2.1%

Topics

  • Cancer-related Molecular Pathways5.4%
  • Immunotherapy and Immune Responses4.2%
  • T-cell and B-cell Immunology2.8%
  • DNA Repair Mechanisms2.6%
  • Immune Cell Function and Interaction2.4%
  • Epigenetics and DNA Methylation2.3%
  • Other80.3%

Coauthors

All papers

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  1. Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246

    Authors: Tomer Cooks, Ioannis S. Pateras, Lisa M. Jenkins, Keval Patel, Ana I. Robles, James Morris, Tim Forshew, Ettore Appella, Vassilis G. Gorgoulis, Curtis C. Harris - Nature Communications 2018 cited by 483

  2. A Rational Strategy to Design Multiepitope Immunogens Based on Multiple Th Lymphocyte Epitopes

    Authors: Brian Livingston, Claire Crimi, Mark J. Newman, Yuichiro Higashimoto, Ettore Appella, John Sidney, Alessandro Sette - The Journal of Immunology 2002 cited by 364

  3. p53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes

    Authors: Abdul M. Mondal, Izumi Horikawa, Sharon R. Pine, Kaori Fujita, Katherine M. Morgan, Elsa Vera, Sharlyn J. Mazur, Ettore Appella, Bořivoj Vojtěšek, Marı́a A. Blasco, David P. Lane, Curtis C. Harris - Journal of Clinical Investigation 2013 cited by 164

  4. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

    Authors: Hwei-Ling Cheng, Raúl Mostoslavsky, Shinichi Saito, John Manis, Yansong Gu, Parin Patel, Roderick T. Bronson, Ettore Appella, Frederick W. Alt, Katrin F. Chua - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 1,090

  5. p300/CBP‐mediated p53 acetylation is commonly induced by p53‐activating agents and inhibited by MDM2

    Authors: Akihiro Ito, Chun-Hsiang Lai, Xuan Zhao, Shinichi Saito, Maria H. Hamilton, Ettore Appella, Tso‐Pang Yao - The EMBO Journal 2001 cited by 575

  6. Modulation of p53 Function by SET8-Mediated Methylation at Lysine 382

    Authors: Xiaobing Shi, Ioulia Kachirskaia, Hiroshi Yamaguchi, Lisandra West, Hong Wen, Evelyn W. Wang, Sucharita Dutta, Ettore Appella, Or Gozani - Molecular Cell 2007 cited by 473

  7. The optimization of helper T lymphocyte (HTL) function in vaccine development

    Authors: Jeff Alexander, John Fikes, Stephen L. Hoffman, Eileen D. Franke, John B. Sacci, Ettore Appella, Francis V. Chisari, Luca G. Guidotti, Robert W. Chesnut, Brian Livingston, Alessandro Sette - Immunologic Research 1998 cited by 146

  8. Characterization of Peptides Bound to the Class I MHC Molecule HLA-A2.1 by Mass Spectrometry

    Authors: Donald F. Hunt, Robert Henderson, Jeffrey Shabanowitz, Kazuyasu Sakaguchi, Hanspeter Michel, Noelle Sevilir, Andrea L. Cox, Ettore Appella, Víctor H. Engelhard - Science 1992 cited by 1,210

  9. DNA damage activates p53 through a phosphorylation–acetylation cascade

    Authors: Kazuyasu Sakaguchi, Julio E. Herrera, Shinichi Saito, Toru Miki, Michael Bustin, Alex Vassilev, Carl W. Anderson, Ettore Appella - Genes & Development 1998 cited by 1,208

  10. Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice

    Authors: Rui-Hong Wang, Kundan Sengupta, Cuiling Li, Hyun‐Seok Kim, Liu Cao, Cuiying Xiao, Sangsoo Kim, Xiaoling Xu, Zheng Yin, Beverly S. Chilton, Rong Jia, Zhi‐Ming Zheng, Ettore Appella, Xin Wei Wang, Thomas Ried, Chu‐Xia Deng - Cancer Cell 2008 cited by 776

  11. MDM2–HDAC1‐mediated deacetylation of p53 is required for its degradation

    Authors: Akihiro Ito, Yoshiharu Kawaguchi, Chun-Hsiang Lai, Jeffrey J. Kovacs, Yuichiro Higashimoto, Ettore Appella, Tso‐Pang Yao - The EMBO Journal 2002 cited by 566

  12. Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

    Authors: Christine E. Canman, Dae‐Sik Lim, Karlene A. Cimprich, Yoichi Taya, Katsuyuki Tamai, Kazuyasu Sakaguchi, Ettore Appella, Michael B. Kastan, Janet D. Siliciano - Science 1998 cited by 2,059

  13. p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

    Authors: Tongxiang Lin, Connie Chao, Shinichi Saito, Sharlyn J. Mazur, Maureen E. Murphy, Ettore Appella, Yang Xu - Nature Cell Biology 2004 cited by 854

  14. Several Common HLA-DR Types Share Largely Overlapping Peptide Binding Repertoires

    Authors: Scott Southwood, John Sidney, Akihiro Kondo, Marie‐France del Guercio, Ettore Appella, Stephen L. Hoffman, Ralph T. Kubo, Robert W. Chesnut, Howard M. Grey, Alessandro Sette - The Journal of Immunology 1998 cited by 661

  15. PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

    Authors: Mark Pearson, Roberta Carbone, Carla Sebastiani, Mario Cioce, M Fagioli, Shinichi Saito, Yuichiro Higashimoto, Ettore Appella, Saverio Minucci, Pier Paolo Pandolfi, Pier Giuseppe Pelicci - Nature 2000 cited by 838

  16. Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses

    Authors: Burhan Uyanik, Anastasia R. Goloudina, Aamir Akbarali, Bogdan B. Grigorash, Alexey Petukhov, Sunil Singhal, Evgeniy Eruslanov, Jeanne Chaloyard, Lisa Lagorgette, Tarik Hadi, E. V. Baidyuk, Hiroyasu Sakai, Lino Tessarollo, Bernhard Ryffel, Sharlyn J. Mazur, Frédéric Lirussi, Carmen Garrido, Ettore Appella, Oleg N. Demidov - Nature Communications 2021 cited by 38

  17. Phosphorylation of human p53 by p38 kinase coordinates N‐terminal phosphorylation and apoptosis in response to UV radiation

    Authors: Bulavin Dv, Shińichi Saito, M. Christine Hollander, Kazuyasu Sakaguchi, Carl W. Anderson, Ettore Appella, Albert J. Fornace - The EMBO Journal 1999 cited by 711

  18. Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

    Authors: Dmitry V. Bulavin, Yuichiro Higashimoto, Ian J. Popoff, William A. Gaarde, Venkatesha Basrur, Olga Potapova, Ettore Appella, Albert J. Fornace - Nature 2001 cited by 527

  19. Studying multisite binary and ternary protein interactions by global analysis of isothermal titration calorimetry data in SEDPHAT: Application to adaptor protein complexes in cell signaling

    Authors: Jon C. D. Houtman, Patrick H. Brown, Brent Bowden, Hiroshi Yamaguchi, Ettore Appella, Lawrence E. Samelson, Peter Schuck - Protein Science 2006 cited by 338

  20. Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

    Authors: Dmitry V. Bulavin, Oleg N. Demidov, Shinichi Saito, Päivikki Kauraniemi, Crissy Phillips, Sally A. Amundson, Concetta Ambrosino, Guido Sauter, Ángel R. Nebreda, Carl W. Anderson, Anne Kallioniemi, Albert J. Fornace, Ettore Appella - Nature Genetics 2002 cited by 442

  21. Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma

    Authors: Veronica Veschi, Zhihui Liu, Ty C. Voss, Laurent Ozbun, Berkley E. Gryder, Chunhua Yan, Ying Hu, Anqi Ma, Jian Jin, Sharlyn J. Mazur, Norris Lam, Bárbara Kunzler Souza, Giuseppe Giannini, Gordon L. Hager, C.H. Arrowsmith, Javed Khan, Ettore Appella, Carol J. Thiele - Cancer Cell 2017 cited by 128

  22. Post‐translational modifications and activation of p53 by genotoxic stresses

    Authors: Ettore Appella, Carl W. Anderson - European Journal of Biochemistry 2001 cited by 1,074

  23. Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines.

    Authors: Teizo Yoshimura, Koji Matsushima, Shuji Tanaka, Elizabeth A. Robinson, Ettore Appella, Joost J. Oppenheim, Edward J. Leonard - National Academy of Sciences, Proceedings of the National Academy of Sciences 1987 cited by 990

  24. Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis

    Authors: Gabriella D’Orazi, Barbara Cecchinelli, Tiziana Bruno, Isabella Manni, Yuichiro Higashimoto, Shinichi Saito, Monica Gostissa, Sabrina Coen, Alessandra Marchetti, Giannino Del Sal, Giulia Piaggio, Maurizio Fanciulli, Ettore Appella, Silvia Soddu - Nature Cell Biology 2001 cited by 679