Michael B. Kastan
Active 1982–2024
- 93
- Papers
- 49,552
- Citations
- 85
- h-index
- 93
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology53.5%
- Medicine38.8%
- Immunology and Microbiology2.4%
- Neuroscience1.2%
- Agricultural and Biological Sciences0.9%
- Chemistry0.5%
- Other2.7%
Topics
- Cancer-related Molecular Pathways10.1%
- DNA Repair Mechanisms9.7%
- Cell death mechanisms and regulation2.8%
- Epigenetics and DNA Methylation2.7%
- Microtubule and mitosis dynamics2.6%
- RNA modifications and cancer2.3%
- Other69.8%
Coauthors
- Christine E. Canman14
- Dae‐Sik Lim8
- Seong‐Tae Kim8
- Bo Xu7
- David G. Kirsch7
- Christopher J. Bakkenist6
- Albert J. Fornace5
- Beverly Plunkett4
- Jacqueline Tait-Mulder4
- Jing Chen4
- Jiří Bártek4
- Kirsteen H. Maclean4
- Michael Goldstein4
- Qimin Zhan4
- Risa Kitagawa4
- Susan E. Morgan4
- Tej K. Pandita4
- Yoichi Taya4
- Yosef Shiloh4
- Angela Alexander3
- Clay F. Semenkovich3
- J. Marie Hardwick3
- Jinhee Kim3
- Jiri Lukas3
All papers
- The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
Authors: Hasan Zaki, Kelli L. Boyd, Peter Vogel, Michael B. Kastan, Mohamed Lamkanfi, Thirumala‐Devi Kanneganti - Immunity 2010 cited by 976
- The DNA Damage Response: Implications for Tumor Responses to Radiation and Chemotherapy
Authors: Michael Goldstein, Michael B. Kastan - Annual Review of Medicine 2014 cited by 597
- DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
Authors: Christopher J. Bakkenist, Michael B. Kastan - Nature 2003 cited by 3,441
- Cell-cycle checkpoints and cancer
Authors: Michael B. Kastan, Jiří Bártek - Nature 2004 cited by 2,828
- ATM functions at the peroxisome to induce pexophagy in response to ROS
Authors: Jiangwei Zhang, Durga Nand Tripathi, Jing Ji, Angela Alexander, Jinhee Kim, Reid T. Powell, Ruhee Dere, Jacqueline Tait-Mulder, Ji‐Hoon Lee, Tanya T. Paull, Raj K. Pandita, Vijaya Charaka, Tej K. Pandita, Michael B. Kastan, Cheryl L. Walker - Nature Cell Biology 2015 cited by 424
- Autophagy Links Inflammasomes to Atherosclerotic Progression
Authors: Babak Razani, Feng Chu, Trey Coleman, Roy Emanuel, Haitao Wen, Seungmin Hwang, Jenny P.‐Y. Ting, Herbert W. Virgin, Michael B. Kastan, Clay F. Semenkovich - Cell Metabolism 2012 cited by 598
- Strategies for optimizing the response of cancer and normal tissues to radiation
Authors: Everett J. Moding, Michael B. Kastan, David G. Kirsch - Nature Reviews Drug Discovery 2013 cited by 467
- Abeloff's Clinical Oncology
Authors: John E. Niederhuber, Jamés O. Armitage, James H. Doroshow, Michael B. Kastan, Joel E. Tepper, Martin D. Abeloff - Elsevier eBooks 2020 cited by 439
- Inactivation of the Human Papillomavirus E6 or E7 Gene in Cervical Carcinoma Cells by Using a Bacterial CRISPR/Cas RNA-Guided Endonuclease
Authors: Edward M. Kennedy, Anand Kornepati, Michael Goldstein, Hal P. Bogerd, Brigid Chiyoko Poling, Adam W. Whisnant, Michael B. Kastan, Bryan R. Cullen - Journal of Virology 2014 cited by 294
- Mitochondrial dysfunction in ataxia-telangiectasia
Authors: Yasmine A. Valentin-Vega, Kirsteen H. Maclean, Jacqueline Tait-Mulder, Sandra Milasta, Meredith A. Steeves, Frank C. Dorsey, John L. Cleveland, Douglas R. Green, Michael B. Kastan - Blood 2011 cited by 369
- ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
Authors: Angela Alexander, Sheng-Li Cai, Jinhee Kim, Adrian Nañez, Mustafa Şahin, Kirsteen H. Maclean, Ken Inoki, Kun‐Liang Guan, Jianjun Shen, Maria D. Person, Donna F. Kusewitt, Gordon B. Mills, Michael B. Kastan, Cheryl Lyn Walker - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 709
- Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53
Authors: Christine E. Canman, Dae‐Sik Lim, Karlene A. Cimprich, Yoichi Taya, Katsuyuki Tamai, Kazuyasu Sakaguchi, Ettore Appella, Michael B. Kastan, Janet D. Siliciano - Science 1998 cited by 2,059
- Substrate Specificities and Identification of Putative Substrates of ATM Kinase Family Members
Authors: Seong‐Tae Kim, Dae‐Sik Lim, Christine E. Canman, Michael B. Kastan - Journal of Biological Chemistry 1999 cited by 814
- Participation of p53 protein in the cellular response to DNA damage.
Authors: Michael B. Kastan, Onyinye Onyekwere, D Sidransky, Bert Vogelstein, R W Craig - 1991 cited by 3,800
- A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
Authors: Michael B. Kastan, Qimin Zhan, Wafik S. El‐Deiry, France Carrier, Tyler Jacks, William V. Walsh, Beverly Plunkett, B Vogelstein, Albert J. Fornace - Cell 1992 cited by 3,088
- The complexity of p53 modulation: emerging patterns from divergent signals
Authors: Amato J. Giaccia, Michael B. Kastan - Genes & Development 1998 cited by 1,312
- A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS
Authors: Jiangwei Zhang, Jinhee Kim, Angela Alexander, Shengli Cai, Durga Nand Tripathi, Ruhee Dere, Andrew R. Tee, Jacqueline Tait-Mulder, Alessia Di Nardo, Juliette M. Han, Erica Kwiatkowski, Elaine A. Dunlop, Kayleigh Dodd, Rebecca D. Folkerth, Phyllis L. Faust, Michael B. Kastan, Mustafa Şahin, Cheryl L. Walker - Nature Cell Biology 2013 cited by 255
- Regulation of p53 Translation and Induction after DNA Damage by Ribosomal Protein L26 and Nucleolin
Authors: Masatoshi Takagi, Michael J. Absalon, Kevin G. McLure, Michael B. Kastan - Cell 2005 cited by 668
- Cell Cycle Control and Cancer
Authors: Leland H. Hartwell, Michael B. Kastan - Science 1994 cited by 2,552
- The many substrates and functions of ATM
Authors: Michael B. Kastan, Dae‐Sik Lim - Nature Reviews Molecular Cell Biology 2000 cited by 774
- Phosphorylation of SMC1 is a critical downstream event in the ATM–NBS1–BRCA1 pathway
Authors: Risa Kitagawa, Christopher J. Bakkenist, Peter J. McKinnon, Michael B. Kastan - Genes & Development 2004 cited by 538
- Caspase-3-dependent Cleavage of Bcl-2 Promotes Release of Cytochrome c
Authors: David G. Kirsch, Andrea I. Doseff, B. Nelson Chau, Dae‐Sik Lim, Nadja C. de Souza‐Pinto, Richard G. Hansford, Michael B. Kastan, Yuri Lazebnik, J. Marie Hardwick - Journal of Biological Chemistry 1999 cited by 464
- Interaction of the p53-Regulated Protein Gadd45 with Proliferating Cell Nuclear Antigen
Authors: Martin L. Smith, I.-Tsuen Chen, Qimin Zhan, Insoo Bae, Chaw-Yuan Chen, Tona M. Gilmer, Michael B. Kastan, Patrick M. O'Connor, Albert J. Fornace - Science 1994 cited by 951
- Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair
Authors: Elijahu Berkovich, Raymond J. Monnat, Michael B. Kastan - Nature Cell Biology 2007 cited by 472
