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Ken Inoki

Active 1999–2025

61
Papers
22,562
Citations
52
h-index
57
i10-index

Citations

Citations per year for Ken Inoki1990: 1 citations1994: 1 citations2001: 1 citations2002: 11 citations2003: 73 citations2004: 170 citations2005: 254 citations2006: 278 citations2007: 285 citations2008: 336 citations2009: 426 citations2010: 380 citations2011: 487 citations2012: 411 citations2013: 393 citations2014: 455 citations2015: 378 citations2016: 365 citations2017: 339 citations2018: 315 citations2019: 730 citations2020: 881 citations2021: 848 citations2022: 592 citations2023: 447 citations2024: 586 citations2025: 293 citations2026: 10 citations1991–1993: no citations, so these years are not shown1995–2000: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,338 citing papers, 32.4% of this breakdownChina: 1,505 citing papers, 14.6% of this breakdownUnited Kingdom: 631 citing papers, 6.1% of this breakdownGermany: 415 citing papers, 4% of this breakdownCanada: 405 citing papers, 3.9% of this breakdownJapan: 340 citing papers, 3.3% of this breakdownFrance: 333 citing papers, 3.2% of this breakdownItaly: 317 citing papers, 3.1% of this breakdownAustralia: 238 citing papers, 2.3% of this breakdownSwitzerland: 219 citing papers, 2.1% of this breakdownSouth Korea: 217 citing papers, 2.1% of this breakdownSpain: 197 citing papers, 1.9% of this breakdown
0%32.4%Other 21%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology51%
  • Medicine40.3%
  • Neuroscience3.9%
  • Immunology and Microbiology2.4%
  • Agricultural and Biological Sciences0.9%
  • Environmental Science0.3%
  • Other1.2%

Topics

  • PI3K/AKT/mTOR signaling in cancer7.9%
  • Autophagy in Disease and Therapy6.9%
  • Metabolism, Diabetes, and Cancer5%
  • Pancreatic function and diabetes2.9%
  • Cancer, Hypoxia, and Metabolism2.3%
  • Protein Kinase Regulation and GTPase Signaling1.7%
  • Other73.3%

Coauthors

All papers

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  1. TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

    Authors: Ken Inoki, Tianqing Zhu, Kun‐Liang Guan - Cell 2003 cited by 3,913

  2. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

    Authors: Ken Inoki, Yong Li, Tianquan Zhu, Jun Wu, Kun‐Liang Guan - Nature Cell Biology 2002 cited by 3,056

  3. Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

    Authors: Ken Inoki, Yong Li, Tian Xu, Kun‐Liang Guan - Genes & Development 2003 cited by 1,915

  4. AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets

    Authors: Ken Inoki, Joungmok Kim, Kun‐Liang Guan - The Annual Review of Pharmacology and Toxicology 2011 cited by 792

  5. Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes

    Authors: Masako Narita, Andrew Young, Satoko Arakawa, Shamith Samarajiwa, Takayuki Nakashima, Sei Yoshida, Sungki Hong, Lorraine Berry, Stefanie Reichelt, Manuela Ferreira, Simon Tavaré, Ken Inoki, Shigeomi Shimizu, Masashi Narita - Science 2011 cited by 597

  6. SGLT2 inhibitors mitigate kidney tubular metabolic and mTORC1 perturbations in youth-onset type 2 diabetes

    Authors: Jennifer A. Schaub, Fadhl Alakwaa, Phillip J. McCown, Abhijit S. Naik, Viji Nair, Sean Eddy, Rajasree Menon, Edgar A. Otto, Dawit Demeke, John R. Hartman, Damian Fermin, Christopher L. O’Connor, Lalita Subramanian, Markus Bitzer, Roger K. Harned, Patricia Ladd, Laura Pyle, Subramaniam Pennathur, Ken Inoki, Jeffrey B. Hodgin, Frank C. Brosius, Robert G. Nelson, Matthias Kretzler, Petter Bjornstad - Journal of Clinical Investigation 2023 cited by 107

  7. Nutrient-sensing mTORC1 and AMPK pathways in chronic kidney diseases

    Authors: Christopher Huynh, Jaewhee Ryu, Jooho Lee, Ayaka Inoki, Ken Inoki - Nature Reviews Nephrology 2022 cited by 93

  8. TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth

    Authors: Ken Inoki, Hongjiao Ouyang, Tianqing Zhu, Charlotta Lindvall, Yian Wang, Xiaojie Zhang, Qian Yang, Christina N. Bennett, Yuko Harada, Kryn Stankunas, Cun-Yu Wang, Xi He, Ormond A. MacDougald, Ming You, Bart O. Williams, Kun‐Liang Guan - Cell 2006 cited by 1,396

  9. AMPK directly activates mTORC2 to promote cell survival during acute energetic stress

    Authors: Dubek Kazyken, Brian Magnuson, Çağrı Bodur, Hugo A. Acosta-Jaquez, Deqiang Zhang, Xin Tong, Tammy M. Barnes, Gabrielle K. Steinl, Nicole Patterson, Christopher Altheim, Naveen Sharma, Ken Inoki, Gregory D. Cartee, Dave Bridges, Lei Yin, Steven M. Riddle, Diane C. Fingar - Science Signaling 2019 cited by 224

  10. Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

    Authors: Markus Gödel, Björn Hartleben, Nadja Herbach, Shuya Liu, Stefan Zschiedrich, Shun Lu, Andrea Debreczeni-Mór, Maja T. Lindenmeyer, Maria-Pia Rastaldi, Götz Hartleben, Thorsten Wiech, Alessia Fornoni, Robert G. Nelson, Matthias Kretzler, Rüdiger Wanke, Hermann Pavenstädt, Dontscho Kerjaschki, Clemens D. Cohen, Michael N. Hall, Markus A. Rüegg, Ken Inoki, Gerd Walz, Tobias B. Huber - Journal of Clinical Investigation 2011 cited by 543

  11. mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

    Authors: Ken Inoki, Hiroyuki Mori, Junying Wang, Tsukasa Suzuki, SungKi Hong, Sei Yoshida, Simone M. Blattner, Tsuneo Ikenoue, Markus A. Rüegg, Michael N. Hall, David J. Kwiatkowski, Maria Pia Rastaldi, Tobias B. Huber, Matthias Kretzler, Lawrence B. Holzman, Roger C. Wiggins, Kun‐Liang Guan - Journal of Clinical Investigation 2011 cited by 531

  12. Glycolytic Enzymes Coalesce in G Bodies under Hypoxic Stress

    Authors: Meiyan Jin, Gregory G. Fuller, Ting Han, Yao Yao, Amelia F. Alessi, Mallory Freeberg, Nathan Roach, James J. Moresco, Alla Karnovsky, Misuzu Baba, John R. Yates, Aaron D. Gitler, Ken Inoki, Daniel J. Klionsky, John K. Kim - Cell Reports 2017 cited by 212

  13. mTORC1 underlies age‐related muscle fiber damage and loss by inducing oxidative stress and catabolism

    Authors: Huibin Tang, Ken Inoki, Susan V. Brooks, Hideki Okazawa, Myung Lee, Junying Wang, Michael Kim, Catherine L. Kennedy, Peter Macpherson, Xuhuai Ji, Sabrina Van Roekel, Danielle Fraga, Kun Wang, Jinguo Zhu, Yoyo Wang, Z. Dave Sharp, Richard A. Miller, Thomas A. Rando, Daniel Goldman, Kun‐Liang Guan, Joseph B. Shrager - Aging Cell 2019 cited by 184

  14. ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

    Authors: Angela Alexander, Sheng-Li Cai, Jinhee Kim, Adrian Nañez, Mustafa Şahin, Kirsteen H. Maclean, Ken Inoki, Kun‐Liang Guan, Jianjun Shen, Maria D. Person, Donna F. Kusewitt, Gordon B. Mills, Michael B. Kastan, Cheryl Lyn Walker - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 709

  15. LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs

    Authors: Sungki Hong, Mallory Freeberg, Ting Han, Avani Kamath, Yao Yao, Tomoko Fukuda, Tsukasa Suzuki, John K. Kim, Ken Inoki - eLife 2017 cited by 213

  16. Emerging role of autophagy in kidney function, diseases and aging

    Authors: Tobias B. Huber, Charles L. Edelstein, Björn Hartleben, Ken Inoki, Man Jiang, Daisuke Koya, Shinji Kume, Wilfred Lieberthal, Nicolas Pallet, Alejandro Quiroga, Kameswaran Ravichandran, Katalin Suszták, Sei Yoshida, Zheng Dong - Autophagy 2012 cited by 251

  17. ER-associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity

    Authors: Lu Liu, Ayaka Inoki, Kelly Fan, Fengbiao Mao, Guojun Shi, Xi Jin, Meiling Zhao, Gina M. Ney, Morgan H. Jones, Shengyi Sun, Yali Dou, Ken Inoki, Ling Qi, Qing Li - Blood 2020 cited by 65

  18. Dysregulation of the TSC-mTOR pathway in human disease

    Authors: Ken Inoki, Michael N. Corradetti, Kun‐Liang Guan - Nature Genetics 2004 cited by 980

  19. Inhibition of AMPK Catabolic Action by GSK3

    Authors: Tsukasa Suzuki, Dave Bridges, Daisuke Nakada, Georgios Skiniotis, Sean J. Morrison, Jiandie D. Lin, Alan R. Saltiel, Ken Inoki - Molecular Cell 2013 cited by 224

  20. Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

    Authors: Tsuneo Ikenoue, Ken Inoki, Qian Yang, Xiaoming Zhou, Kun‐Liang Guan - The EMBO Journal 2008 cited by 608

  21. Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome

    Authors: Michael N. Corradetti, Ken Inoki, Nabeel Bardeesy, Ronald A. DePinho, Kun‐Liang Guan - Genes & Development 2004 cited by 565

  22. PP2A-dependent TFEB activation is blocked by PIKfyve-induced mTORC1 activity

    Authors: Junya Hasegawa, Emi Tokuda, Yao Yao, Takehiko Sasaki, Ken Inoki, Lois S. Weisman - Molecular Biology of the Cell 2022 cited by 40

  23. Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity

    Authors: Qian Yang, Ken Inoki, Tsuneo Ikenoue, Kun‐Liang Guan - Genes & Development 2006 cited by 522

  24. mTORC1 Promotes Denervation-Induced Muscle Atrophy Through a Mechanism Involving the Activation of FoxO and E3 Ubiquitin Ligases

    Authors: Huibin Tang, Ken Inoki, Myung Lee, Erika Wright, Andy Khuong, Amanda Khuong, Sista Sugiarto, Matthew Garner, Jihye Paik, Ronald A. DePinho, Daniel Goldman, Kun‐Liang Guan, Joseph B. Shrager - Science Signaling 2014 cited by 151