Gary Ruvkun
Active 1980–2025
- 151
- Papers
- 54,546
- Citations
- 103
- h-index
- 142
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology77.9%
- Medicine9.6%
- Agricultural and Biological Sciences5.2%
- Neuroscience3.1%
- Immunology and Microbiology1.5%
- Environmental Science1.1%
- Other1.6%
Topics
- Genetics, Aging, and Longevity in Model Organisms10.2%
- MicroRNA in disease regulation8.7%
- Cancer-related molecular mechanisms research4.2%
- Circular RNAs in diseases3.9%
- RNA Research and Splicing3.8%
- RNA modifications and cancer3.5%
- Other65.7%
Coauthors
- Peter C. Breen12
- Amy E. Pasquinelli9
- Christopher E. Carr9
- Michael Finney9
- Frederick M. Ausubel7
- Scott Kennedy7
- Sylvia E. J. Fischer7
- Harrison W. Gabel6
- Nicolas J. Lehrbach6
- Oliver Hobert6
- Taiowa A. Montgomery6
- Bruce Wightman5
- Eyleen J. O’Rourke5
- Frank J. Slack5
- H. Robert Horvitz5
- Heidi A. Tissenbaum5
- Ravi S. Kamath5
- Victor Ambros5
- Carolyn M. Phillips4
- Chi Zhang4
- Christian G. Riedel4
- Craig C. Mello4
- Gabriel D. Hayes4
- Ho Yi Mak4
All papers
- Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
Authors: Bruce Wightman, Ilho Ha, Gary Ruvkun - Cell 1993 cited by 4,271
- The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
Authors: Brenda J. Reinhart, Frank J. Slack, Michael Basson, Amy E. Pasquinelli, Jill C. Bettinger, Ann E. Rougvie, H. Robert Horvitz, Gary Ruvkun - Nature 2000 cited by 4,988
- Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
Authors: Amy E. Pasquinelli, Brenda J. Reinhart, Frank J. Slack, Mark Q. Martindale, Mitzi I. Kuroda, Betsy Maller, David C. Hayward, Eldon E. Ball, Bernard M. Degnan, Peter Müller, Jürg Spring, Ashok Srinivasan, Mark C. Fishman, John R. Finnerty, Joseph C. Corbo, Michael Levine, Patrick Leahy, Eric A. Davidson, Gary Ruvkun - Nature 2000 cited by 2,565
- daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
Authors: Koutarou D. Kimura, Heidi A. Tissenbaum, Yanxia Liu, Gary Ruvkun - Science 1997 cited by 2,289
- High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
Authors: Schraga Schwartz, Sudeep D. Agarwala, Maxwell R. Mumbach, Marko Jovanović, Philipp Mertins, A.A. Shishkin, Yuval Tabach, Tarjei S. Mikkelsen, Rahul Satija, Gary Ruvkun, Steven A. Carr, Eric S. Lander, Gerald R. Fink, Aviv Regev - Cell 2013 cited by 655
- A uniform system for microRNA annotation
Authors: Victor Ambros, Bonnie Bartel, David P. Bartel, Christopher B. Burge, James C. Carrington, Xuemei Chen, Gideon Dreyfuss, Sean R. Eddy, Sam Griffiths‐Jones, Mhairi Marshall, Marjori Matzke, Gary Ruvkun, Thomas Tuschl - RNA 2003 cited by 1,902
- Caenorhabditis elegans responses to bacteria from its natural habitats
Authors: Buck S. Samuel, Holli Rowedder, Christian Braendle, Marie‐Anne Félix, Gary Ruvkun - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 445
- Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing
Authors: Alla Grishok, Amy E. Pasquinelli, Darryl Conte, Na Li, Susan Parrish, Ilho Ha, David L. Baillie, Andrew Fire, Gary Ruvkun, Craig C. Mello - Cell 2001 cited by 1,889
- Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
Authors: Justine A. Melo, Gary Ruvkun - Cell 2012 cited by 417
- The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
Authors: Scott Ogg, Suzanne Paradis, S Gottlieb, Garth I. Patterson, Linda Lee, Heidi A. Tissenbaum, Gary Ruvkun - Nature 1997 cited by 1,976
- DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
Authors: Xin-Xuan Lin, Ilke Sen, Georges E. Janssens, Xin Zhou, Bryan R. Fonslow, Daniel Edgar, Nicholas Stroustrup, Peter Swoboda, John R. Yates, Gary Ruvkun, Christian G. Riedel - Nature Communications 2018 cited by 179
- Long-Lived C. elegans daf-2 Mutants Are Resistant to Bacterial Pathogens
Authors: Danielle A. Garsin, Jacinto Villanueva, Jakob Begun, Dennis H. Kim, Costi D. Sifri, Stephen B. Calderwood, Gary Ruvkun, Frederick M. Ausubel - Science 2003 cited by 626
- Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
Authors: Tslil Ast, Joshua D. Meisel, Shachin Patra, Hong Wang, Robert M. H. Grange, Sharon Kim, Sarah E. Calvo, Lauren L. Orefice, Fumiaki Nagashima, Fumito Ichinose, Warren M. Zapol, Gary Ruvkun, D.P. Barondeau, Vamsi K. Mootha - Cell 2019 cited by 172
- C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles
Authors: Eyleen J. O’Rourke, Alexander A. Soukas, Christopher E. Carr, Gary Ruvkun - Cell Metabolism 2009 cited by 478
- Caenorhabditis elegans pathways that surveil and defend mitochondria
Authors: Ying Liu, Buck S. Samuel, Peter C. Breen, Gary Ruvkun - Nature 2014 cited by 319
- MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
Authors: Eyleen J. O’Rourke, Gary Ruvkun - Nature Cell Biology 2013 cited by 335
- Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1
Authors: Nicolas J. Lehrbach, Gary Ruvkun - eLife 2016 cited by 249
- Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
Authors: Nicolas J. Lehrbach, Peter C. Breen, Gary Ruvkun - Cell 2019 cited by 137
- ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy
Authors: Eyleen J. O’Rourke, Petric Kuballa, Ramnik J. Xavier, Gary Ruvkun - Genes & Development 2013 cited by 192
- Regulation and Functions of the ER-Associated Nrf1 Transcription Factor
Authors: Gary Ruvkun, Nicolas J. Lehrbach - Cold Spring Harbor Perspectives in Biology 2022 cited by 58
- DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
Authors: Siu Sylvia Lee, Scott Kennedy, Andrew C. Tolonen, Gary Ruvkun - Science 2003 cited by 680
- Lifespan Regulation by Evolutionarily Conserved Genes Essential for Viability
Authors: Sean P. Curran, Gary Ruvkun - PLoS Genetics 2007 cited by 500
- Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death
Authors: Natalia V. Kirienko, Daniel R. Kirienko, Jonah Larkins‐Ford, Carolina Wählby, Gary Ruvkun, Frederick M. Ausubel - Cell Host & Microbe 2013 cited by 221
- Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity
Authors: Nicolas J. Lehrbach, Gary Ruvkun - eLife 2019 cited by 87
