Gregory A. Petsko
Active 1975–2024
- 153
- Papers
- 35,559
- Citations
- 102
- h-index
- 150
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology47%
- Medicine25.2%
- Materials Science6%
- Chemistry5.7%
- Neuroscience3.7%
- Computer Science2.9%
- Other9.5%
Topics
- Protein Structure and Dynamics7.7%
- Enzyme Structure and Function5.7%
- Parkinson's Disease Mechanisms and Treatments3.8%
- Computational Drug Discovery Methods2.3%
- Alzheimer's disease research and treatments2.2%
- RNA and protein synthesis mechanisms1.8%
- Other76.5%
Coauthors
- Dagmar Ringe70
- George L. Kenyon11
- Martin Karplus11
- Scott A. Small9
- J.A. Gerlt8
- Mark A. Wilson7
- Quyen Q. Hoang7
- Shulin Ju7
- Demetrius Tsernoglou6
- John W. Kozarich5
- Bjarne Rasmussen4
- Dali Liu4
- David J. Neidhart4
- Elias Lolis4
- Hans Frauenfelder4
- Mark Cookson4
- Pei W. Thomas4
- R. Davenport4
- Robert F. Tilton4
- S.K. Burley4
- Walter Fast4
- A. C. Bloomer3
- Ann Stock3
- Benjamin C. Campbell3
All papers
- Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson’s Disease
Authors: Jeffrey S. Schweitzer, Bin Song, Todd M. Herrington, Tae Yoon Park, Nayeon Lee, Sanghyeok Ko, Jeha Jeon, Young Cha, Kyungsang Kim, Quanzheng Li, Claire Henchcliffe, Michael G. Kaplitt, Carolyn Neff, Otto Rapalino, Hyemyung Seo, In‐Hee Lee, Ji‐Sun Kim, Taewoo Kim, Gregory A. Petsko, Jerome Ritz, Bruce M. Cohen, Sek-Won Kong, Pierre Leblanc, Bob S. Carter, Kwang‐Soo Kim - New England Journal of Medicine 2020 cited by 518
- CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
Authors: Yu‐Hwa Huang, Chen Zhu, Yasuyuki Kondo, Ana C. Anderson, Amit Gandhi, Andrew B. Russell, Stephanie K. Dougan, Britt‐Sabina Petersen, Espen Melum, Thomas Pertel, Kiera Clayton, Monika Raab, Qiang Chen, Nicole Beauchemin, Paul J. Yazaki, Michał Pyzik, Mario Ostrowski, Jonathan N. Glickman, Christopher E. Rudd, Hidde L. Ploegh, André Franke, Gregory A. Petsko, Vijay K. Kuchroo, Richard S. Blumberg - Nature 2014 cited by 727
- Molecular dynamics simulations in biology
Authors: Martin Karplus, Gregory A. Petsko - Nature 1990 cited by 1,173
- Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations
Authors: Benjamin Dehay, Mathieu Bourdenx, Philippe Gorry, Serge Przedborski, Miquel Vila, Stéphane Hunot, Andrew Singleton, C. Warren Olanow, Kalpana Merchant, Erwan Bézard, Gregory A. Petsko, Wassilios G. Meissner - The Lancet Neurology 2015 cited by 509
- mGreenLantern: a bright monomeric fluorescent protein with rapid expression and cell filling properties for neuronal imaging
Authors: Benjamin C. Campbell, Elisa M. Nabel, Mitchell H. Murdock, Cristina Lao‐Peregrín, Pantelis Tsoulfas, Murray G. Blackmore, Francis S. Lee, Conor Liston, Hirofumi Morishita, Gregory A. Petsko - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 cited by 182
- Aromatic-Aromatic Interaction: A Mechanism of Protein Structure Stabilization
Authors: S.K. Burley, Gregory A. Petsko - Science 1985 cited by 2,535
- AAVrh.10-Mediated APOE2 Central Nervous System Gene Therapy for APOE4-Associated Alzheimer's Disease
Authors: Jonathan B. Rosenberg, Michael G. Kaplitt, Bishnu P. De, Alvin Chen, Thomas Flagiello, Christiana O. Salami, Eduard Pey, Lingzhi Zhao, Rodolfo J Ricart Arbona, Sébastien Monette, Jonathan P. Dyke, Douglas Ballon, Stephen M. Kaminsky, Dolan Sondhi, Gregory A. Petsko, Steven M. Paul, Ronald G. Crystal - Human Gene Therapy Clinical Development 2018 cited by 162
- Intrinsic motions along an enzymatic reaction trajectory
Authors: Katherine A. Henzler‐Wildman, Vu Thai, Ming Lei, Maria Ott, Magnus Wolf‐Watz, Tim D. Fenn, Edwin Pozharski, Mark A. Wilson, Gregory A. Petsko, Martin Karplus, Christian G. Hübner, Dorothee Kern - Nature 2007 cited by 915
- 25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner
Authors: Man Ying Wong, Michael Lewis, James Doherty, Yang Shi, Anil G. Cashikar, Anna Amelianchik, Svitlana Tymchuk, Patrick M. Sullivan, Mingxing Qian, Douglas F. Covey, Gregory A. Petsko, David M. Holtzman, Steven M. Paul, Wenjie Luo - Journal of Neuroinflammation 2020 cited by 118
- A soluble α-synuclein construct forms a dynamic tetramer
Authors: Wei Wang, Iva Perovic, Johnathan Chittuluru, Alice Kaganovich, Linh Hồ Thùy Nguyễn, Jingling Liao, Jared R. Auclair, Derrick E. Johnson, Anuradha Landeru, Alana K. Simorellis, Shulin Ju, Mark Cookson, Francisco J. Asturias, Jeffrey N. Agar, B.N. Webb, ChulHee Kang, Dagmar Ringe, Gregory A. Petsko, Thomas C. Pochapsky, Quyen Q. Hoang - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 466
- Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations
Authors: Andrew M. Intlekofer, Alan H. Shih, Bo Wang, Abbas Nazir, Ariën S. Rustenburg, Steven K. Albanese, Minal Patel, Christopher Famulare, Fabian Correa, Naofumi Takemoto, Vidushi Durani, Hui Liu, Justin Taylor, Noushin Farnoud, Elli Papaemmanuil, Justin R. Cross, Martin S. Tallman, Maria E. Arcila, Mikhail Roshal, Gregory A. Petsko, Bin Wu, Sung Choe, Zenon Konteatis, Scott A. Biller, John D. Chodera, Craig B. Thompson, Ross L. Levine, Eytan M. Stein - Nature 2018 cited by 280
- Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synuclein
Authors: Wei Wang, Linh Hồ Thùy Nguyễn, Christopher Burlak, Fariba Chegini, Feng Guo, Tim Chataway, Shulin Ju, Oriana S. Fisher, David W. Miller, Debajyoti Datta, Fang Wu, Chun-Xiang Wu, Anuradha Landeru, James A. Wells, Mark Cookson, Matthew B. Boxer, Craig J. Thomas, Wei Gai, Dagmar Ringe, Gregory A. Petsko, Quyen Q. Hoang - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 266
- Polyamine pathway contributes to the pathogenesis of Parkinson disease
Authors: Nicole Lewandowski, Shulin Ju, Miguel Verbitsky, Barbara Ross, Melissa L. Geddie, Edward Rockenstein, Anthony Adame, Alim Muhammad, Jean Paul Vonsattel, Dagmar Ringe, Lucien Côté, Susan Lindquist, Eliezer Masliah, Gregory A. Petsko, Karen Marder, Lorraine N. Clark, Scott A. Small - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 159
- Endosomal Traffic Jams Represent a Pathogenic Hub and Therapeutic Target in Alzheimer’s Disease
Authors: Scott A. Small, Sabrina Simoes-Spassov, Richard Mayeux, Gregory A. Petsko - Trends in Neurosciences 2017 cited by 170
- The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
Authors: Rosa Canet-Aviles, Mark A. Wilson, David W. Miller, Rili Ahmad, Chris McLendon, Sourav Bandyopadhyay, Melisa J. Baptista, Dagmar Ringe, Gregory A. Petsko, Mark Cookson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 cited by 1,120
- The Catalytic Pathway of Cytochrome P450cam at Atomic Resolution
Authors: Ilme Schlichting, Joel Berendzen, Kelvin Chu, Ann Stock, Shelley A. Maves, David E. Benson, Robert M. Sweet, Dagmar Ringe, Gregory A. Petsko, Stephen G. Sligar - Science 2000 cited by 1,334
- Induced pluripotent stem cells: a tool for modeling Parkinson’s disease
Authors: Anindita Bose, Gregory A. Petsko, Lorenz Studer - Trends in Neurosciences 2022 cited by 65
- Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s disease
Authors: Chun‐Hyung Kim, Baek‐Soo Han, Jisook Moon, Deog-Joong Kim, Joon Shin, S. S. Rajan, Quoc Toan Nguyen, Mi‐Jin Sohn, Won‐Gon Kim, Min-Joon Han, Inhye Jeong, Kyoung‐Shim Kim, Eun-Hye Lee, Yupeng Tu, Jacqueline L. Naffin-Olivos, Chang‐Hwan Park, Dagmar Ringe, Ho Sup Yoon, Gregory A. Petsko, Kwang‐Soo Kim - National Academy of Sciences, Proceedings of the National Academy of Sciences 2015 cited by 196
- Chemically stable fluorescent proteins for advanced microscopy
Authors: Benjamin C. Campbell, Maria G. Paez-Segala, Loren L. Looger, Gregory A. Petsko, Ce Feng Liu - Nature Methods 2022 cited by 73
- PGE1 and PGA1 bind to Nurr1 and activate its transcriptional function
Authors: S. S. Rajan, Yongwoo Jang, Chun‐Hyung Kim, Woori Kim, Hui Ting Toh, Jeha Jeon, Bin Song, Aida Serra, Julien Lescar, Jun Yeob Yoo, Serap Beldar, Ye Hong, CongBao Kang, Xue‐Wei Liu, Melissa Feitosa, Yeahan Kim, Dabin Hwang, Geraldine Goh, Kah‐Leong Lim, Hye Min Park, Choong Hwan Lee, Sungwhan F. Oh, Gregory A. Petsko, Ho Sup Yoon, Kwang‐Soo Kim - Nature Chemical Biology 2020 cited by 89
- The 1.1-Å resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease
Authors: Mark A. Wilson, Jennifer L. Collins, Yaacov Hod, Dagmar Ringe, Gregory A. Petsko - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 315
- How Enzymes Work
Authors: Dagmar Ringe, Gregory A. Petsko - Science 2008 cited by 259
- Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR
Authors: D.A. Keedy, Henry van den Bedem, David A. Sivak, Gregory A. Petsko, Dagmar Ringe, Mark A. Wilson, James S. Fraser - Structure 2014 cited by 165
- Parkinson’s Disease and Melanoma: Co-Occurrence and Mechanisms
Authors: Anindita Bose, Gregory A. Petsko, David Eliezer - Journal of Parkinson s Disease 2018 cited by 114
