Harold Varmus
Active 1969–2025
- 212
- Papers
- 73,977
- Citations
- 131
- h-index
- 209
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology44.1%
- Medicine39%
- Immunology and Microbiology5.9%
- Agricultural and Biological Sciences2.3%
- Computer Science2.1%
- Neuroscience1.5%
- Other5.1%
Topics
- Lung Cancer Treatments and Mutations3.8%
- Wnt/β-catenin signaling in development and cancer3.1%
- Cancer Genomics and Diagnostics2.8%
- Cancer-related gene regulation2.2%
- Virus-based gene therapy research1.9%
- Cancer-related Molecular Pathways1.6%
- Other84.6%
Coauthors
- J. Michael Bishop55
- Don Ganem10
- Katerina Politi9
- Arthur D. Levinson7
- G M Ringold7
- Gregory M. Shackleford7
- Mario Chamorro7
- Peter R. Shank7
- Roel Nusse7
- Stephen H. Hughes7
- William Pao7
- Anthony M.C. Brown6
- John Majors6
- Maureen F. Zakowski6
- Nancy Quintrell6
- William W. Lockwood6
- Brian C. Lewis5
- Deborah H. Spector5
- Hermann Oppermann5
- Katrina Podsypanina5
- Manfred Schwab5
- Mark G. Kris5
- Patrick O. Brown5
- Ramareddy V. Guntaka5
All papers
- A New Initiative on Precision Medicine
Authors: Francis S. Collins, Harold Varmus - New England Journal of Medicine 2015 cited by 5,179
- Toward a Shared Vision for Cancer Genomic Data
Authors: Robert L. Grossman, Allison P. Heath, Vincent Ferretti, Harold Varmus, Douglas R. Lowy, Warren A. Kibbe, Louis M. Staudt - New England Journal of Medicine 2016 cited by 1,808
- Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
Authors: Roel Nusse, Harold Varmus - Cell 1982 cited by 1,855
- Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain
Authors: William Pao, Vincent A. Miller, Katerina Politi, Gregory J. Riely, Romel Somwar, Maureen F. Zakowski, Mark G. Kris, Harold Varmus - PLoS Medicine 2005 cited by 3,526
- Somatic mutations affect key pathways in lung adenocarcinoma
Authors: Li Ding, Gad Getz, David A. Wheeler, Elaine R. Mardis, Michael D. McLellan, Kristian Cibulskis, Carrie Sougnez, Heidi Greulich, Donna M. Muzny, Margaret Morgan, Lucinda Fulton, Robert S. Fulton, Qunyuan Zhang, Michael C. Wendl, Michael S. Lawrence, David E. Larson, Ken Chen, David J. Dooling, Aniko Sabo, Alicia Hawes, Hua Shen, Shalini N. Jhangiani, Lora Lewis, Otis Hall, Yiming Zhu, Tittu Mathew, Yanru Ren, Jiqiang Yao, Steven E. Scherer, Kerstin Clerc, Ginger Metcalf, Brian Ng, Aleksandar Milosavljevic, Manuel L. Gonzalez‐Garay, John R. Osborne, Rick Meyer, Xiaoqi Shi, Yuzhu Tang, Daniel C. Koboldt, Ling Lin, Rachel M. Abbott, Tracie L. Miner, Craig Pohl, Ginger Fewell, Carrie A. Haipek, Heather K. Schmidt, Brian H. Dunford-Shore, Aldi T. Kraja, Seth D. Crosby, Christopher S. Sawyer, Tammi L. Vickery, Sacha N Sander, Jody S. Robinson, Wendy Winckler, Jennifer Baldwin, Lucian R. Chirieac, Amit Dutt, Tim Fennell, Megan Hanna, Bruce E. Johnson, Robert C. Onofrio, Roman K. Thomas, Giovanni Tonon, Barbara A. Weir, Xiao‐Jun Zhao, Liuda Ziaugra, Michael C. Zody, Thomas J. Giordano, Mark B. Orringer, Jack A. Roth, Margaret R. Spitz, Ignacio I. Wistuba, Bradley A. Ozenberger, Peter J. Good, Andrew C. Chang, David G. Beer, Mark A. Watson, Marc Ladanyi, Stephen Broderick, Akihiko Yoshizawa, William D. Travis, William Pao, Michael A. Province, George M. Weinstock, Harold Varmus, Stacey Gabriel, Eric S. Lander, Richard A. Gibbs, Matthew Meyerson, Richard K. Wilson - Nature 2008 cited by 2,750
- EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib
Authors: William Pao, Vincent A. Miller, Maureen F. Zakowski, Jennifer A. Doherty, Katerina Politi, Inderpal S. Sarkaria, Bhuvanesh Singh, Robert T. Heelan, Valerie W. Rusch, Lucinda A. Fulton, Elaine R. Mardis, Doris M. Kupfer, Richard K. Wilson, Mark G. Kris, Harold Varmus - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 cited by 4,344
- Lineage-specific intolerance to oncogenic drivers restricts histological transformation
Authors: Eric E. Gardner, Ethan M. Earlie, Kate Li, Jerin Thomas, Melissa J. Hubisz, Benjamin D. Stein, Chen Zhang, Lewis C. Cantley, Ashley M. Laughney, Harold Varmus - Science 2024 cited by 91
- Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage
Authors: Garrett M. Brodeur, Robert C. Seeger, Manfred Schwab, Harold Varmus, J. Michael Bishop - Science 1984 cited by 2,288
- Epstein-Barr Virus: An Important Vaccine Target for Cancer Prevention
Authors: Jeffrey I. Cohen, Anthony S. Fauci, Harold Varmus, Gary J. Nabel - Science Translational Medicine 2011 cited by 386
- KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib
Authors: William Pao, Theresa Y. Wang, Gregory J. Riely, Vincent A. Miller, Qiulu Pan, Marc Ladanyi, Maureen F. Zakowski, Robert T. Heelan, Mark G. Kris, Harold Varmus - PLoS Medicine 2005 cited by 1,525
- Rescuing US biomedical research from its systemic flaws
Authors: Bruce Alberts, Marc W. Kirschner, Shirley M. Tilghman, Harold Varmus - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 811
- Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy
Authors: Jordi Barretina, Barry S. Taylor, Shantanu Banerji, Alexis Ramos, Mariana Lagos‐Quintana, Penelope DeCarolis, Kinjal Shah, Nicholas D. Socci, Barbara A. Weir, Alan L. Ho, Derek Y. Chiang, Boris Reva, Craig H. Mermel, Gad Getz, Yevgenyi Antipin, Rameen Beroukhim, John E. Major, Charles Hatton, Richard Nicoletti, Megan Hanna, Ted Sharpe, Tim Fennell, Kristian Cibulskis, Robert C. Onofrio, Tsuyoshi Saito, Neerav Shukla, Christopher Lau, Sven Nelander, Serena J. Silver, Carrie Sougnez, Agnès Viale, Wendy Winckler, Robert G. Maki, Levi A. Garraway, Alex Lash, Heidi Greulich, David E. Root, William R. Sellers, Gary K. Schwartz, Cristina R. Antonescu, Eric S. Lander, Harold Varmus, Marc Ladanyi, Chris Sander, Matthew Meyerson, Samuel Singer - Nature Genetics 2010 cited by 726
- Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma
Authors: Arun M. Unni, William W. Lockwood, Kreshnik Zejnullahu, Shih-Queen Lee-Lin, Harold Varmus - eLife 2015 cited by 205
- Lung adenocarcinomas induced in mice by mutant EGF receptors foundin human lung cancers respondto a tyrosine kinase inhibitor orto down-regulation of the receptors
Authors: Katerina Politi, Maureen F. Zakowski, Pang‐Dian Fan, Emily Schonfeld, William Pao, Harold Varmus - Genes & Development 2006 cited by 486
- Mutational landscape of EGFR- , MYC- , and Kras- driven genetically engineered mouse models of lung adenocarcinoma
Authors: David G. McFadden, Katerina Politi, Arjun Bhutkar, Frances K. Chen, Xiaoling Song, Mono Pirun, Philip M. Santiago, Caroline Kim-Kiselak, James T. Platt, Emily Lee, Emily Hodges, Adam P. Rosebrock, Roderick T. Bronson, Nicholas D. Socci, Gregory J. Hannon, Tyler Jacks, Harold Varmus - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 209
- DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA
Authors: D. Stéhelin, Harold Varmus, J. Michael Bishop, Peter K. Vogt - Nature 1976 cited by 1,320
- Characterizing the cancer genome in lung adenocarcinoma
Authors: Barbara A. Weir, Michele Sue‐Ann Woo, Gad Getz, Sven Perner, Li Ding, Rameen Beroukhim, William M. Lin, Michael A. Province, Aldi T. Kraja, Laura A. Johnson, Kinjal Shah, Mitsuo Sato, Roman K. Thomas, Justine A. Barletta, Ingrid B. Borecki, Stephen Broderick, Andrew C. Chang, Derek Y. Chiang, Lucian R. Chirieac, Jeonghee Cho, Yoshitaka Fujii, Adi F. Gazdar, Thomas J. Giordano, Heidi Greulich, Megan Hanna, Bruce E. Johnson, Mark G. Kris, Alex Lash, Ling Lin, Neal I. Lindeman, Elaine R. Mardis, John D. McPherson, John D. Minna, Margaret Morgan, Mark Nadel, Mark B. Orringer, John R. Osborne, Brad Ozenberger, Alex H. Ramos, James Robinson, Jack A. Roth, Valerie W. Rusch, Hidefumi Sasaki, Frances A. Shepherd, Carrie Sougnez, Margaret R. Spitz, Ming‐Sound Tsao, David Twomey, Roel G.W. Verhaak, George M. Weinstock, David A. Wheeler, Wendy Winckler, Akihiko Yoshizawa, Soyoung Yu, Maureen F. Zakowski, Qunyuan Zhang, David G. Beer, Ignacio I. Wistuba, Mark A. Watson, Levi A. Garraway, Marc Ladanyi, William D. Travis, William Pao, Mark A. Rubin, Stacey Gabriel, Richard A. Gibbs, Harold Varmus, Richard K. Wilson, Eric S. Lander, Matthew Meyerson - Nature 2007 cited by 1,125
- Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines
Authors: Romel Somwar, Hediye Erdjument‐Bromage, Erik Larsson, David Shum, William W. Lockwood, Guangli Yang, Chris Sander, Ouathek Ouerfelli, Paul Tempst, Hakim Djaballah, Harold Varmus - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 159
- Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells
Authors: Arun M. Unni, Bryant Harbourne, Min Hee Oh, Sophia A. Wild, John R. Ferrarone, William W. Lockwood, Harold Varmus - eLife 2018 cited by 114
- Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells
Authors: Huanhuan Joyce Chen, Asaf Poran, Arun M. Unni, Sarah X.L. Huang, Olivier Elemento, Hans‐Willem Snoeck, Harold Varmus - The Journal of Experimental Medicine 2019 cited by 102
- Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour
Authors: Manfred Schwab, Kari Alitalo, Karl-Heinz Klempnauer, Harold Varmus, J. Michael Bishop, Fred Gilbert, Garrett M. Brodeur, Milton N. Goldstein, Jeffrey M. Trent - Nature 1983 cited by 1,427
- Characterization of ribosomal frameshifting in HIV-1 gag-pol expression
Authors: Tyler Jacks, Michael D. Power, Frank R. Masiarz, Paul A. Luciw, Philip J. Barr, Harold Varmus - Nature 1988 cited by 951
- Three decades of Wnts: a personal perspective on how a scientific field developed
Authors: Roel Nusse, Harold Varmus - The EMBO Journal 2012 cited by 409
- Wnt signals across the plasma membrane to activate the β-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP
Authors: Feng Cong, Liang Schweizer, Harold Varmus - Development 2004 cited by 352
