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Haruki Okamura

Active 1989–2025

79
Papers
20,113
Citations
69
h-index
77
i10-index

Citations

Citations per year for Haruki Okamura1984: 6 citations1992: 2 citations1993: 4 citations1994: 13 citations1995: 12 citations1996: 15 citations1997: 75 citations1998: 305 citations1999: 485 citations2000: 582 citations2001: 582 citations2002: 422 citations2003: 349 citations2004: 349 citations2005: 194 citations2006: 253 citations2007: 200 citations2008: 188 citations2009: 141 citations2010: 171 citations2011: 162 citations2012: 132 citations2013: 120 citations2014: 125 citations2015: 109 citations2016: 85 citations2017: 126 citations2018: 111 citations2019: 327 citations2020: 286 citations2021: 285 citations2022: 298 citations2023: 174 citations2024: 263 citations2025: 125 citations1985–1991: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 1,570 citing papers, 29.7% of this breakdownJapan: 532 citing papers, 10.1% of this breakdownChina: 433 citing papers, 8.2% of this breakdownGermany: 315 citing papers, 5.9% of this breakdownUnited Kingdom: 278 citing papers, 5.3% of this breakdownFrance: 197 citing papers, 3.7% of this breakdownAustralia: 178 citing papers, 3.4% of this breakdownCanada: 162 citing papers, 3.1% of this breakdownItaly: 154 citing papers, 2.9% of this breakdownNetherlands: 135 citing papers, 2.5% of this breakdownSwitzerland: 111 citing papers, 2.1% of this breakdownSouth Korea: 97 citing papers, 1.8% of this breakdown
0%29.7%Other 21.3%

Institutions

Fields

  • Medicine33%
  • Biochemistry, Genetics and Molecular Biology30.5%
  • Immunology and Microbiology28.4%
  • Neuroscience3.1%
  • Nursing2.1%
  • Agricultural and Biological Sciences1.1%
  • Other1.8%

Topics

  • Inflammasome and immune disorders8.6%
  • Immune Cell Function and Interaction7.5%
  • Immune Response and Inflammation5%
  • T-cell and B-cell Immunology3.4%
  • IL-33, ST2, and ILC Pathways2.9%
  • Immunotherapy and Immune Responses2.5%
  • Other70.1%

Coauthors

All papers

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  1. Cloning of a new cytokine that induces IFN-γ production by T cells

    Authors: Haruki Okamura, Hiroko Tsutsui, Toshinori Komatsu, Masuo Yutsudo, Akira Hakura, Tadao Tanimoto, Kakuji Torigoe, Takanori Okura, Yoshiyuki Nukada, Kazuko Hattori, Kenji Akita, Motoshi Namba, Fujimi Tanabe, Kaori Konishi, Shigeharu Fukuda, Masashi Kurimoto - Nature 1995 cited by 2,621

  2. Interleukin-18 Regulates Both Th1 and Th2 Responses

    Authors: Kenji Nakanishi, Tomohiro Yoshimoto, Hiroko Tsutsui, Haruki Okamura - Annual Review of Immunology 2001 cited by 1,318

  3. Activation of Interferon-γ Inducing Factor Mediated by Interleukin-1β Converting Enzyme

    Authors: Yong Gu, Keisuke Kuida, Hiroko Tsutsui, George Ku, Kathy Hsiao, Mark Fleming, Nobuki Hayashi, Kazuya Higashino, Haruki Okamura, Kenji Nakanishi, Masashi Kurimoto, Tadao Tanimoto, Richard A. Flavell, Vicki L. Sato, Matthew W. Harding, David J. Livingston, Michael Su - Science 1997 cited by 1,162

  4. IL-12 Up-Regulates IL-18 Receptor Expression on T Cells, Th1 Cells, and B Cells: Synergism with IL-18 for IFN-γ Production

    Authors: Tomohiro Yoshimoto, Kiyoshi Takeda, Takashi Tanaka, Kazunobu Ohkusu, Shin‐ichiro Kashiwamura, Haruki Okamura, Shizuo Akira, Kenji Nakanishi - The Journal of Immunology 1998 cited by 667

  5. Regulation of interferon-γ production by IL-12 and IL-18

    Authors: Haruki Okamura, Shin‐ichiro Kashiwamura, Hiroko Tsutsui, Tomohiro Yoshimoto, Kenji Nakanishi - Current Opinion in Immunology 1998 cited by 527

  6. IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production.

    Authors: Tomohiro Yoshimoto, Kiyoshi Takeda, Takashi Tanaka, Kazunobu Ohkusu, Shin‐ichiro Kashiwamura, Haruki Okamura, Shizuo Akira, Kenji Nakanishi - 1998 cited by 774

  7. IL-12 synergizes with IL-18 or IL-1β for IFN-γ production from human T cells

    Authors: Kouji Tominaga, Tomohiro Yoshimoto, Kakuji Torigoe, Masashi Kurimoto, Kiyoshi Matsui, Toshikazu Hada, Haruki Okamura, Kenji Nakanishi - International Immunology 2000 cited by 333

  8. Interleukin-18-Mediated Microglia/Astrocyte Interaction in the Spinal Cord Enhances Neuropathic Pain Processing after Nerve Injury

    Authors: Kan Miyoshi, Koichi Obata, Takashi Kondo, Haruki Okamura, Koichi Noguchi - Journal of Neuroscience 2008 cited by 280

  9. Defective NK Cell Activity and Th1 Response in IL-18–Deficient Mice

    Authors: Kiyoshi Takeda, Hiroko Tsutsui, Tomohiro Yoshimoto, Osamu Adachi, Nobuaki Yoshida, T. Kishimoto, Haruki Okamura, Kenji Nakanishi, Shizuo Akira - Immunity 1998 cited by 914

  10. IL-18 induction of IgE: dependence on CD4+ T cells, IL-4 and STAT6

    Authors: Tomohiro Yoshimoto, Hitoshi Mizutani, Hiroko Tsutsui, Nancy Noben-Trauth, Keiichi Yamanaka, Minoru Tanaka, Shinzo Izumi, Haruki Okamura, William E. Paul, Kenji Nakanishi - Nature Immunology 2000 cited by 349

  11. Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice

    Authors: Kyosuke Yamanishi, Nobutaka Doe, Keiichiro Mukai, Takuya Hashimoto, Naomi Gamachi, Masaki Hata, Yuko Watanabe, Chiaki Yamanishi, Hideshi Yagi, Haruki Okamura, Hisato Matsunaga - Translational Psychiatry 2022 cited by 27

  12. Elevated levels of interleukin-18 and tumor necrosis factor-α in serum of patients with type 2 diabetes mellitus: Relationship with diabetic nephropathy

    Authors: Yuji Moriwaki, Tetsuya Yamamoto, Yuhei Shibutani, Eiji Aoki, Zenta Tsutsumi, Sumio Takahashi, Haruki Okamura, Masafumi Koga, Minoru Fukuchi, Toshikazu Hada - Metabolism 2003 cited by 270

  13. Lipopolysaccharide-Induced IL-18 Secretion from Murine Kupffer Cells Independently of Myeloid Differentiation Factor 88 That Is Critically Involved in Induction of Production of IL-12 and IL-1β

    Authors: Ekihiro Seki, Hiroko Tsutsui, Hiroki Nakano, Noriko M. Tsuji, Katsuaki Hoshino, Osamu Adachi, Keishi Adachi, Shizue Futatsugi, Keisuke Kuida, Osamu Takeuchi, Haruki Okamura, Jiro Fujimoto, Shizuo Akira, Kenji Nakanishi - The Journal of Immunology 2001 cited by 232

  14. Effect of IL-18 on the Expansion and Phenotype of Human Natural Killer Cells: Application to Cancer Immunotherapy

    Authors: Hiroaki Senju, Asuka Kumagai, Yoichi Nakamura, Hiroyuki Yamaguchi, Katsumi Nakatomi, Shota Fukami, Kengo Shiraishi, Yuka Harada, Mitsuhiro Nakamura, Haruki Okamura, Yoshimasa Tanaka, Hiroshi Mukae - International Journal of Biological Sciences 2018 cited by 84

  15. Augmentation of Immune Checkpoint Cancer Immunotherapy with IL18

    Authors: Zhifeng Ma, Wen Li, Shinichi Yoshiya, Yunfeng Xu, Masaki Hata, Yosif El‐Darawish, Tzvetanka Markova, Kyosuke Yamanishi, Hiromichi Yamanishi, Hideaki Tahara, Yoshimasa Tanaka, Haruki Okamura - Clinical Cancer Research 2016 cited by 99

  16. IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils

    Authors: Tomohiro Yoshimoto, Hiroko Tsutsui, Kouji Tominaga, Katsuaki Hoshino, Haruki Okamura, Shizuo Akira, William E. Paul, Kenji Nakanishi - National Academy of Sciences, Proceedings of the National Academy of Sciences 1999 cited by 436

  17. IL-12 regulates the expansion, phenotype, and function of murine NK cells activated by IL-15 and IL-18

    Authors: Naoto Oka, Tzvetanka Markova, Kenzo Tsuzuki, Wen Li, Yosif El‐Darawish, Magdalena Pencheva-Demireva, Kyousuke Yamanishi, Hiromichi Yamanishi, Masafumi Sakagami, Yoshimasa Tanaka, Haruki Okamura - Cancer Immunology Immunotherapy 2020 cited by 65

  18. Molecular Mechanisms of IL18 in Disease

    Authors: Kyosuke Yamanishi, Masaki Hata, Naomi Gamachi, Yuko Watanabe, Chiaki Yamanishi, Haruki Okamura, Hisato Matsunaga - International Journal of Molecular Sciences 2023 cited by 21

  19. Endotoxin-induced serum factor that stimulates gamma interferon production

    Authors: Kumiko Nakamura, Haruki Okamura, M Wada, Kumiko Nagata, Toshihide Tamura - Infection and Immunity 1989 cited by 302

  20. Neutrophil Proteinase 3-Mediated Induction of Bioactive IL-18 Secretion by Human Oral Epithelial Cells

    Authors: Shunji Sugawara, Akiko Uehara, Tomonori Nochi, Takahiro Yamaguchi, Haruyasu Ueda, Akiko Sugiyama, Kazuo Hanzawa, Katsuo Kumagai, Haruki Okamura, Haruhiko Takada - The Journal of Immunology 2001 cited by 296

  21. IFN-γ-Inducing Factor/IL-18 Administration Mediates IFN-γ- and IL-12-Independent Antitumor Effects

    Authors: Tadashi Osaki, Jean‐Marie Péron, Quan-Ying Cai, Haruki Okamura, Paul D. Robbins, Masashi Kurimoto, Michael T. Lotze, Hideaki Tahara - The Journal of Immunology 1998 cited by 192

  22. Interleukin-18: A Novel Cytokine That Augments Both Innate and Acquired Immunity

    Authors: Haruki Okamura, Hiroko Tsutsui, Shin‐ichiro Kashiwamura, Tomohiro Yoshimoto, Kenji Nakanishi - Advances in immunology 1998 cited by 455

  23. Interleukin-18 (Interferon-γ–inducing Factor) Is Produced by Osteoblasts and Acts Via Granulocyte/Macrophage Colony-stimulating Factor and Not Via Interferon-γ to Inhibit Osteoclast Formation

    Authors: Nobuyuki Udagawa, Nicole J. Horwood, Jan Elliott, Alan Mackay, Jane G. Owens, Haruki Okamura, Masashi Kurimoto, Timothy Chambers, T John Martin, Matthew T. Gillespie - The Journal of Experimental Medicine 1997 cited by 376

  24. A novel costimulatory factor for gamma interferon induction found in the livers of mice causes endotoxic shock

    Authors: Haruki Okamura, Kumiko Nagata, Tatsuji Komatsu, Tadao Tanimoto, Y Nukata, Fujimi Tanabe, Keiichi Akita, K Torigoe, Takanori Okura, Shigeharu Fukuda - Infection and Immunity 1995 cited by 342