Henk Granzier
Active 1989–2025
- 147
- Papers
- 20,363
- Citations
- 89
- h-index
- 139
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine59.9%
- Biochemistry, Genetics and Molecular Biology29.5%
- Engineering3.3%
- Physics and Astronomy2.4%
- Neuroscience1.4%
- Immunology and Microbiology0.8%
- Other2.7%
Topics
- Cardiomyopathy and Myosin Studies12%
- Muscle Physiology and Disorders7.6%
- Cardiovascular Function and Risk Factors6.5%
- Cardiovascular Effects of Exercise3.6%
- Cardiac Fibrosis and Remodeling2.4%
- Heart Failure Treatment and Management2.4%
- Other65.5%
Coauthors
- Siegfried Labeit55
- Coen A. C. Ottenheijm20
- Christian Witt18
- K Trombitás18
- Yiming Wu16
- John E. Smith15
- Mark McNabb13
- Mei Methawasin13
- Carol C. Gregorio12
- Justin Kolb11
- Carlos Hidalgo10
- Chandra Saripalli10
- D. Labeit10
- Joshua Strom10
- Robbert van der Pijl10
- Jochen Gohlke9
- Johan Lindqvist9
- Michael Gotthardt9
- Zaynab Hourani9
- Martin M. LeWinter8
- Paola Tonino8
- Thomas C. Irving8
- Thomas Centner8
- Michiel Helmes7
All papers
- Research Priorities for Heart Failure With Preserved Ejection Fraction
Authors: Sanjiv J. Shah, Barry A. Borlaug, Dalane W. Kitzman, Andrew D. McCulloch, Burns C. Blaxall, Rajiv Agarwal, Julio A. Chirinos, Sheila Collins, Rahul C. Deo, Mark T. Gladwin, Henk Granzier, Scott L. Hummel, David A. Kass, Margaret M. Redfield, Flora Sam, Thomas J. Wang, Patrice Desvigne‐Nickens, Bishow B. Adhikari - Circulation 2020 cited by 417
- Myocardial Stiffness in Patients With Heart Failure and a Preserved Ejection Fraction
Authors: Michael R. Zile, Catalin F. Baicu, John S. Ikonomidis, Robert E. Stroud, Paul J. Nietert, Amy D. Bradshaw, Rebecca Slater, Bradley M. Palmer, Peter Van Buren, Markus Meyer, Margaret M. Redfield, David A. Bull, Henk Granzier, Martin M. LeWinter - Circulation 2015 cited by 666
- Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism
Authors: Mark Y. Jeong, Ying Lin, Sara A. Wennersten, Kimberly Demos-Davies, Maria A. Cavasin, Jennifer H. Mahaffey, V. Monzani, Chandrasekhar Saripalli, Paolo Mascagni, T. Brett Reece, Amrut V. Ambardekar, Henk Granzier, Charles A. Dinarello, Timothy A. McKinsey - Science Translational Medicine 2018 cited by 162
- The Complete Gene Sequence of Titin, Expression of an Unusual ≈700-kDa Titin Isoform, and Its Interaction With Obscurin Identify a Novel Z-Line to I-Band Linking System
Authors: Marie‐Louise Bang, Thomas Centner, Friderike Fornoff, Adam J. Geach, Michael Gotthardt, Mark McNabb, Christian Witt, D. Labeit, Carol C. Gregorio, Henk Granzier, Siegfried Labeit - Circulation Research 2001 cited by 716
- HDAC6 modulates myofibril stiffness and diastolic function of the heart
Authors: Ying‐Hsi Lin, Jennifer L. Major, Tim Liebner, Zaynab Hourani, Joshua G. Travers, Sara A. Wennersten, Korey R. Haefner, Maria A. Cavasin, Cortney E. Wilson, Mark Y. Jeong, Yu Han, Michael Gotthardt, Scott K. Ferguson, Amrut V. Ambardekar, Maggie P. Y. Lam, Chunaram Choudhary, Henk Granzier, Kathleen C. Woulfe, Timothy A. McKinsey - Journal of Clinical Investigation 2022 cited by 51
- MMP inhibitors attenuate doxorubicin cardiotoxicity by preventing intracellular and extracellular matrix remodelling
Authors: Brandon Chan, Andrej Roczkowsky, Woo Jung Cho, Mathieu Poirier, Consolato Sergi, Vic Keschrumrus, Jared M. Churko, Henk Granzier, Richard Schulz - Cardiovascular Research 2020 cited by 106
- Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy
Authors: Brenda Gerull, Michael Gramlich, J. Atherton, Mark McNabb, K Trombitás, Sabine Klaassen, Jonathan G. Seidman, Christine E. Seidman, Henk Granzier, Siegfried Labeit, Michael Frenneaux, Ludwig Thierfelder - Nature Genetics 2002 cited by 621
- Positive End-Expiratory Pressure Ventilation Induces Longitudinal Atrophy in Diaphragm Fibers
Authors: Johan Lindqvist, Marloes van den Berg, Robbert van der Pijl, Pleuni E. Hooijman, Albertus Beishuizen, Judith Elshof, Monique de Waard, Armand R. J. Girbes, A. Man, Zhonghua Shi, Charissa E. van den Brom, Sylvia J. P. Bogaards, Shengyi Shen, Joshua Strom, Henk Granzier, Jeroen Kole, René J.P. Musters, Marinus A. Paul, Leo Heunks, Coen A. C. Ottenheijm - American Journal of Respiratory and Critical Care Medicine 2018 cited by 113
- Cardiac Titin and Heart Disease
Authors: Martin M. LeWinter, Henk Granzier - Journal of Cardiovascular Pharmacology 2013 cited by 151
- Right Ventricular Diastolic Impairment in Patients With Pulmonary Arterial Hypertension
Authors: Silvia Rain, M. Louis Handoko, Pia Trip, C. Tji Gan, Nico Westerhof, Ger J.M. Stienen, Walter J. Paulus, Coen A. C. Ottenheijm, J. Tim Marcus, Peter Dorfmüller, Christophe Guignabert, Marc Humbert, Peter S. Macdonald, Cristobal G. dos Remedios, Piet E. Postmus, Chandra Saripalli, Carlos Hidalgo, Henk Granzier, Anton Vonk Noordegraaf, Jolanda van der Velden, Frances S. de Man - Circulation 2013 cited by 363
- Developmental Control of Titin Isoform Expression and Passive Stiffness in Fetal and Neonatal Myocardium
Authors: Sunshine Lahmers, Yiming Wu, Douglas R. Call, Siegfried Labeit, Henk Granzier - Circulation Research 2004 cited by 316
- Differential Expression of Cardiac Titin Isoforms and Modulation of Cellular Stiffness
Authors: Olivier Cazorla, Alexandra Freiburg, Michiel Helmes, Thomas Centner, Mark McNabb, Yingliang Wu, K Trombitás, Siegfried Labeit, Henk Granzier - Circulation Research 2000 cited by 416
- Protein Kinase A Phosphorylates Titin’s Cardiac-Specific N2B Domain and Reduces Passive Tension in Rat Cardiac Myocytes
Authors: Rob Yamasaki, Yidong Wu, Mark McNabb, Marion L. Greaser, Siegfried Labeit, Henk Granzier - Circulation Research 2002 cited by 307
- Differential sex-dependent susceptibility to diastolic dysfunction and arrhythmia in cardiomyocytes from obese diabetic heart failure with preserved ejection fraction model
Authors: Juliana Mira Hernández, Erin Y. Shen, Christopher Y. Ko, Zaynab Hourani, Emily R. Spencer, Daria Smoliarchuk, Julie Bossuyt, Henk Granzier, Donald M. Bers, Bence Hegyi - Cardiovascular Research 2024 cited by 34
- The Giant Protein Titin
Authors: Henk Granzier, Siegfried Labeit - Circulation Research 2004 cited by 647
- Series of Exon-Skipping Events in the Elastic Spring Region of Titin as the Structural Basis for Myofibrillar Elastic Diversity
Authors: Alexandra Freiburg, K Trombitás, Wolfgang Hell, Olivier Cazorla, Françoise Fougerousse, Thomas Centner, Bernhard Kolmerer, Christian Witt, J. Beckmann, Carol C. Gregorio, Henk Granzier, Siegfried Labeit - Circulation Research 2000 cited by 389
- PKC Phosphorylation of Titin’s PEVK Element
Authors: Carlos Hidalgo, Bryan D. Hudson, Julius Bogomolovas, Yi Zhu, Brian Anderson, Marion L. Greaser, Siegfried Labeit, Henk Granzier - Circulation Research 2009 cited by 259
- The Muscle Ankyrin Repeat Proteins: CARP, ankrd2/Arpp and DARP as a Family of Titin Filament-based Stress Response Molecules
Authors: Melanie K. Miller, Marie‐Louise Bang, Christian Witt, D. Labeit, C Trombitás, Kaori Watanabe, Henk Granzier, Abigail McElhinny, Carol C. Gregorio, Siegfried Labeit - Journal of Molecular Biology 2003 cited by 350
- Cardiac Titin
Authors: Martin M. LeWinter, Henk Granzier - Circulation 2010 cited by 262
- Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function In a Mouse Model of Heart Failure With Preserved Ejection Fraction
Authors: Mei Methawasin, Joshua Strom, Rebecca Slater, Vanessa Fernandez, Chandra Saripalli, Henk Granzier - Circulation 2016 cited by 117
- The multifunctional Ca2+/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements
Authors: Carlos Hidalgo, Charles S. Chung, Chandra Saripalli, Mei Methawasin, Kirk R. Hutchinson, George Tsaprailis, Siegfried Labeit, Alicia Mattiazzi, Henk Granzier - Journal of Molecular and Cellular Cardiology 2012 cited by 84
- Altered Titin Expression, Myocardial Stiffness, and Left Ventricular Function in Patients With Dilated Cardiomyopathy
Authors: Sherif F. Nagueh, Gopi Shah, Yiming Wu, Guillermo Torre‐Amione, Nicholas M. P. King, Sunshine Lahmers, Christian Witt, K Becker, Siegfried Labeit, Henk Granzier - Circulation 2004 cited by 486
- Titin Develops Restoring Force in Rat Cardiac Myocytes
Authors: Michiel Helmes, Ka ́roly Trombita ́s, Henk Granzier - Circulation Research 1996 cited by 255
- Congenital Titinopathy: Comprehensive characterization and pathogenic insights
Authors: Emily C. Oates, Kristi Jones, Sandra Donkervoort, Amanda Charlton, Susan Brammah, John E. Smith, James S. Ware, Kyle S. Yau, Lindsay C. Swanson, Nicola Whiffin, Anthony Peduto, Adam Bournazos, Leigh B. Waddell, Michelle A. Farrar, Hugo Sampaio, Hooi Ling Teoh, Phillipa J. Lamont, David Mowat, Robin B. Fitzsimons, Alastair Corbett, Monique M. Ryan, Gina O’Grady, Sarah A. Sandaradura, Roula Ghaoui, Himanshu Joshi, Jamie L. Marshall, Melinda Nolan, Simranpreet Kaur, Jaya Punetha, Ana Töpf, Elizabeth Harris, Madhura Bakshi, Casie A. Genetti, M. Marttila, Ulla Werlauff, Nathalie Streichenberger, Alan Pestronk, Ingrid Mazanti, Jason Pinner, Carole Vuillerot, Carla Grosmann, Ana Camacho, Payam Mohassel, M. Leach, A. Reghan Foley, Diana Bharucha‐Goebel, James J. Collins, Anne M. Connolly, Heather R. Gilbreath, Susan T. Iannaccone, Diana Castro, Beryl B. Cummings, Richard Webster, Leïla Lazaro, John Vissing, Sandra Coppens, Nicolas Deconinck, Ho‐Ming Luk, Neil H. Thomas, Nicola Foulds, Marjorie Illingworth, Sian Ellard, Catriona McLean, Rahul Phadke, Gianina Ravenscroft, Nanna Witting, Peter Hackman, Isabelle Richard, Sandra T. Cooper, Erik‐Jan Kamsteeg, Eric P. Hoffman, Kate Bushby, Volker Straub, Bjarne Udd, Ana Ferreiro, Kathryn N. North, Nigel F. Clarke, Monkol Lek, Alan H. Beggs, C. Bönnemann, Daniel G. MacArthur, Henk Granzier, Mark R. Davis, Nigel G. Laing - Annals of Neurology 2018 cited by 164
