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Hiroshi Takayanagi

Active 1997–2025

131
Papers
36,061
Citations
90
h-index
124
i10-index

Citations

Citations per year for Hiroshi Takayanagi1980: 7 citations1986: 1 citations1999: 3 citations2000: 19 citations2001: 48 citations2002: 70 citations2003: 103 citations2004: 119 citations2005: 238 citations2006: 218 citations2007: 256 citations2008: 324 citations2009: 386 citations2010: 290 citations2011: 310 citations2012: 443 citations2013: 371 citations2014: 330 citations2015: 363 citations2016: 285 citations2017: 372 citations2018: 414 citations2019: 1,262 citations2020: 1,514 citations2021: 1,357 citations2022: 1,196 citations2023: 930 citations2024: 1,393 citations2025: 750 citations2026: 25 citations1981–1985: no citations, so these years are not shown1987–1998: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,834 citing papers, 23.6% of this breakdownChina: 2,506 citing papers, 20.9% of this breakdownJapan: 1,048 citing papers, 8.7% of this breakdownGermany: 586 citing papers, 4.9% of this breakdownUnited Kingdom: 572 citing papers, 4.8% of this breakdownAustralia: 392 citing papers, 3.3% of this breakdownSouth Korea: 366 citing papers, 3% of this breakdownItaly: 341 citing papers, 2.8% of this breakdownFrance: 308 citing papers, 2.6% of this breakdownCanada: 278 citing papers, 2.3% of this breakdownNetherlands: 217 citing papers, 1.8% of this breakdownSwitzerland: 163 citing papers, 1.3% of this breakdown
0%23.6%Other 20%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology42.2%
  • Medicine28.3%
  • Immunology and Microbiology18.1%
  • Neuroscience3.2%
  • Dentistry3.1%
  • Engineering2.6%
  • Other2.5%

Topics

  • Bone Metabolism and Diseases12%
  • Bone health and treatments5.4%
  • Immune Cell Function and Interaction3.2%
  • Bone health and osteoporosis research3.1%
  • T-cell and B-cell Immunology3.1%
  • Immune Response and Inflammation2.3%
  • Other70.9%

Coauthors

All papers

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  1. Mechanisms of joint destruction in rheumatoid arthritis — immune cell–fibroblast–bone interactions

    Authors: Noriko Komatsu, Hiroshi Takayanagi - Nature Reviews Rheumatology 2022 cited by 497

  2. Osteoimmunology: evolving concepts in bone–immune interactions in health and disease

    Authors: Masayuki Tsukasaki, Hiroshi Takayanagi - Nature reviews. Immunology 2019 cited by 753

  3. Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

    Authors: Noriko Komatsu, Kazuo Okamoto, Shinichiro Sawa, Tomoki Nakashima, Masatsugu Oh‐hora, Tatsuhiko Kodama, Sakae Tanaka, Jeffrey A. Bluestone, Hiroshi Takayanagi - Nature Medicine 2013 cited by 1,128

  4. Osteoimmunology: The Conceptual Framework Unifying the Immune and Skeletal Systems

    Authors: Kazuo Okamoto, Tomoki Nakashima, Masahiro Shinohara, Takako Negishi‐Koga, Noriko Komatsu, Asuka Terashima, Shinichiro Sawa, Takeshi Nitta, Hiroshi Takayanagi - Physiological Reviews 2017 cited by 517

  5. Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts

    Authors: Hiroshi Takayanagi, Sunhwa Kim, Takako Koga, Hiroshi Nishina, Masashi Isshiki, Hiroki Yoshida, Akio Saiura, Miho Isobe, Taeko Yokochi, Jun‐ichiro Inoue, Erwin F. Wagner, Tak W. Mak, Tatsuhiko Kodama, Tadatsugu Taniguchi - Developmental Cell 2002 cited by 2,679

  6. Evidence for osteocyte regulation of bone homeostasis through RANKL expression

    Authors: Tomoki Nakashima, Mikihito Hayashi, Takanobu Fukunaga, K. Kurata, Masatsugu Oh‐hora, Jian Q. Feng, Lynda F. Bonewald, Tatsuhiko Kodama, Anton Wutz, Erwin F. Wagner, Josef Penninger, Hiroshi Takayanagi - Nature Medicine 2011 cited by 1,747

  7. Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems

    Authors: Hiroshi Takayanagi - Nature reviews. Immunology 2007 cited by 1,832

  8. Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells

    Authors: Daisuke Takahashi, Naomi Hoshina, Yuma Kabumoto, Yuichi Maeda, Akari Suzuki, Hiyori Tanabe, Junya Isobe, Takahiro Yamada, Kisara Muroi, Yuto Yanagisawa, Atsuo Nakamura, Yumiko Fujimura, Aiko Saeki, Mizuki Ueda, Ryohtaroh Matsumoto, Hanako Asaoka, Julie M. Clarke, Yohsuke Harada, Eiji Umemoto, Noriko Komatsu, Takaharu Okada, Hiroshi Takayanagi, Kiyoshi Takeda, Michio Tomura, Koji Hase - EBioMedicine 2020 cited by 189

  9. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

    Authors: Kojiro Sato, Ayako Suematsu, Kazuo Okamoto, A. Yamaguchi, Yasuyuki Morishita, Yuho Kadono, Sakae Tanaka, Tatsuhiko Kodama, Shizuo Akira, Yoichiro Iwakura, Daniel J. Cua, Hiroshi Takayanagi - The Journal of Cell Biology 2006 cited by 1,525

  10. The molecular understanding of osteoclast differentiation

    Authors: Masataka Asagiri, Hiroshi Takayanagi - Bone 2006 cited by 1,384

  11. Host defense against oral microbiota by bone-damaging T cells

    Authors: Masayuki Tsukasaki, Noriko Komatsu, Kazuki Nagashima, Takeshi Nitta, Warunee Pluemsakunthai, Chisa Shukunami, Yoichiro Iwakura, Tomoki Nakashima, Kazuo Okamoto, Hiroshi Takayanagi - Nature Communications 2018 cited by 315

  12. Osteoprotection by semaphorin 3A

    Authors: Mikihito Hayashi, Tomoki Nakashima, Masahiko Taniguchi, Tatsuhiko Kodama, Atsushi Kumanogoh, Hiroshi Takayanagi - Nature 2012 cited by 600

  13. T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ

    Authors: Hiroshi Takayanagi, Kouetsu Ogasawara, Shigeaki Hida, Tomoki Chiba, Shigeo Murata, Kojiro Sato, Akinori Takaoka, Taeko Yokochi, Hiromi Oda, Keiji Tanaka, Kozo Nakamura, Tadatsugu Taniguchi - Nature 2000 cited by 1,363

  14. Estrogen Prevents Bone Loss via Estrogen Receptor α and Induction of Fas Ligand in Osteoclasts

    Authors: Takashi Nakamura, Yuuki Imai, Takahiro Μatsumoto, Shingo Sato, Kazusane Takeuchi, Katsuhide Igarashi, Yoshifumi Harada, Yoshiaki Azuma, Andrée Krust, Yoko Yamamoto, Hiroshi Nishina, Shu Takeda, Hiroshi Takayanagi, Daniel METZGER, Jun Kanno, Kunio Takaoka, T.J. Martin, Pierre Chambon, Shigeaki Kato - Cell 2007 cited by 1,008

  15. The Mechanisms of T Cell Selection in the Thymus

    Authors: Hiroyuki Takaba, Hiroshi Takayanagi - Trends in Immunology 2017 cited by 276

  16. Endoplasmic reticulum mediates mitochondrial transfer within the osteocyte dendritic network

    Authors: Junjie Gao, An Qin, Delin Liu, Rui Ruan, Qiyang Wang, Jun Yuan, Tak Sum Cheng, Aleksandra Filipovska, J. M. Papadimitriou, Kerong Dai, Qing Jiang, Xiang Gao, Jian Q. Feng, Hiroshi Takayanagi, Changqing Zhang, Minghao Zheng - Science Advances 2019 cited by 109

  17. Fezf2 Orchestrates a Thymic Program of Self-Antigen Expression for Immune Tolerance

    Authors: Hiroyuki Takaba, Yasuyuki Morishita, Yoshihiko Tomofuji, Lynett Danks, Takeshi Nitta, Noriko Komatsu, Tatsuhiko Kodama, Hiroshi Takayanagi - Cell 2015 cited by 384

  18. Suppression of bone formation by osteoclastic expression of semaphorin 4D

    Authors: Takako Negishi‐Koga, Masahiro Shinohara, Noriko Komatsu, Haruhiko Bito, Tatsuhiko Kodama, Roland H. Friedel, Hiroshi Takayanagi - Nature Medicine 2011 cited by 495

  19. IL-17-producing γδ T cells enhance bone regeneration

    Authors: T. Ono, Kazuo Okamoto, Tomoki Nakashima, Takeshi Nitta, Shohei Hori, Yoichiro Iwakura, Hiroshi Takayanagi - Nature Communications 2016 cited by 360

  20. RANKL as the master regulator of osteoclast differentiation

    Authors: Hiroshi Takayanagi - Journal of Bone and Mineral Metabolism 2021 cited by 167

  21. Stepwise cell fate decision pathways during osteoclastogenesis at single-cell resolution

    Authors: Masayuki Tsukasaki, Nam Cong‐Nhat Huynh, Kazuo Okamoto, Ryunosuke Muro, Asuka Terashima, Yoshitaka Kurikawa, Noriko Komatsu, Warunee Pluemsakunthai, Takeshi Nitta, Takaya Abe, Hiroshi Kiyonari, Tadashi Okamura, Mashito Sakai, Toshiya Matsukawa, Michihiro Matsumoto, Yasuhiro Kobayashi, Josef Penninger, Hiroshi Takayanagi - Nature Metabolism 2020 cited by 136

  22. Autoamplification of NFATc1 expression determines its essential role in bone homeostasis

    Authors: Masataka Asagiri, Kojiro Sato, Takako Usami, Sae Ochi, Hiroshi Nishina, Hiroki Yoshida, Ikuo Morita, Erwin F. Wagner, Tak W. Mak, Edgar Serfling, Hiroshi Takayanagi - The Journal of Experimental Medicine 2005 cited by 848

  23. RANKL expressed on synovial fibroblasts is primarily responsible for bone erosions during joint inflammation

    Authors: Lynett Danks, Noriko Komatsu, Matteo M. Guerrini, Shinichiro Sawa, Marietta Armaka, George Kollias, Tomoki Nakashima, Hiroshi Takayanagi - Annals of the Rheumatic Diseases 2015 cited by 228

  24. Osteoimmunology

    Authors: Kazuo Okamoto, Hiroshi Takayanagi - Cold Spring Harbor Perspectives in Medicine 2018 cited by 137