Jeffrey A. Bluestone
Active 1985–2025
- 280
- Papers
- 86,448
- Citations
- 158
- h-index
- 276
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine37.3%
- Immunology and Microbiology36.2%
- Biochemistry, Genetics and Molecular Biology22.1%
- Neuroscience1.8%
- Engineering0.7%
- Agricultural and Biological Sciences0.4%
- Other1.5%
Topics
- Immune Cell Function and Interaction11.9%
- T-cell and B-cell Immunology10.9%
- Immunotherapy and Immune Responses6.6%
- Cancer Immunotherapy and Biomarkers4%
- Diabetes and associated disorders3.8%
- CAR-T cell therapy research3.6%
- Other59.2%
Coauthors
- Qizhi Tang45
- Kevan C. Herold24
- Anne I. Sperling15
- Stephen E. Gitelman14
- Gregory L. Szot13
- Amy Putnam12
- Theresa L. Walunas12
- Mark S. Anderson11
- Alexander Marson10
- Benoı̂t L. Salomon10
- Craig B. Thompson10
- Deborah J. Lenschow10
- Arabella Young9
- H Bour9
- Jonathan H. Esensten9
- Peter A. Gottlieb9
- Samantha L. Bailey-Bucktrout9
- Frédéric Van Gool8
- Louis A. Matis8
- Lukas T. Jeker8
- Stephen D. Miller8
- Todd M. Brusko8
- Abul K. Abbas7
- Brian T. Fife7
All papers
- Multiple early factors anticipate post-acute COVID-19 sequelae
Authors: Yapeng Su, Dan Yuan, Daniel Chen, Raymond T. Ng, Kai Wang, Jongchan Choi, Sarah Li, Sunga Hong, Rongyu Zhang, Jingyi Xie, Sergey A. Kornilov, Kelsey Scherler, Ana Jimena Pavlovitch-Bedzyk, Shen Dong, Christopher Lausted, Inyoul Lee, Shannon Fallen, Chengzhen L. Dai, Priyanka Baloni, Brett Smith, Venkata R. Duvvuri, Kristin G. Anderson, Jing Li, Fan Yang, Caroline J. Duncombe, Denise J. McCulloch, Clifford Rostomily, Pamela Troisch, Jing Zhou, Sean Mackay, Quinn DeGottardi, Damon May, Ruth Taniguchi, Rachel Gittelman, Mark Klinger, Thomas M. Snyder, Ryan Roper, Gladys Wojciechowska, Kim M. Murray, Rick Edmark, Simon Evans, Lesley Jones, Yong Zhou, Lee Rowen, Rachel Liu, William Chour, Heather A. Algren, William R. Berrington, Julie A. Wallick, Rebecca A. Cochran, Mary Micikas, Terri Wrin, Christos J. Petropoulos, Hunter Cole, Trevan Fischer, Wei Wei, Dave S.�B. Hoon, Nathan D. Price, Naeha Subramanian, Joshua A. Hill, Jennifer Hadlock, Andrew T. Magis, Antoni Ribas, Lewis L. Lanier, Scott D. Boyd, Jeffrey A. Bluestone, Helen Y. Chu, Leroy Hood, Raphaël Gottardo, Philip D. Greenberg, Mark M. Davis, Jason D. Goldman, James R. Heath - Cell 2022 cited by 1,220
- An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes
Authors: Kevan C. Herold, Brian N. Bundy, S. Alice Long, Jeffrey A. Bluestone, Linda A. DiMeglio, Matthew J. Dufort, Stephen E. Gitelman, Peter A. Gottlieb, Jeffrey P. Krischer, Peter S. Linsley, Jennifer B. Marks, Wayne D. Moore, Antoinette Moran, Henry Rodriguez, William E. Russell, Desmond Schatz, Jay S. Skyler, Eva Tsalikian, Diane K. Wherrett, Anette-Gabriele Ziegler, Carla J. Greenbaum - New England Journal of Medicine 2019 cited by 1,112
- Treg cell-based therapies: challenges and perspectives
Authors: Caroline Raffin, Linda T. Vo, Jeffrey A. Bluestone - Nature reviews. Immunology 2019 cited by 706
- CD28 Costimulation: From Mechanism to Therapy
Authors: Jonathan H. Esensten, Ynes Helou, Gaurav Chopra, Arthur Weiss, Jeffrey A. Bluestone - Immunity 2016 cited by 947
- Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis
Authors: Noriko Komatsu, Kazuo Okamoto, Shinichiro Sawa, Tomoki Nakashima, Masatsugu Oh‐hora, Tatsuhiko Kodama, Sakae Tanaka, Jeffrey A. Bluestone, Hiroshi Takayanagi - Nature Medicine 2013 cited by 1,128
- Type 1 diabetes immunotherapy using polyclonal regulatory T cells
Authors: Jeffrey A. Bluestone, Jane H. Buckner, Mark Fitch, Stephen E. Gitelman, Shipra Gupta, Marc K. Hellerstein, Kevan C. Herold, Angela Lares, Michael R. F. Lee, Kelvin Li, Weihong Liu, S. Alice Long, Lisa M. Masiello, Vinh Nguyen, Amy Putnam, Mary Rieck, Peter H. Sayre, Qizhi Tang - Science Translational Medicine 2015 cited by 1,013
- Revisiting IL-2: Biology and therapeutic prospects
Authors: Abul K. Abbas, Eleonora Trotta, Dimitre R. Simeonov, Alexander Marson, Jeffrey A. Bluestone - Science Immunology 2018 cited by 633
- Next-generation regulatory T cell therapy
Authors: Leonardo M. R. Ferreira, Yannick D. Müller, Jeffrey A. Bluestone, Qizhi Tang - Nature Reviews Drug Discovery 2019 cited by 473
- Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasis
Authors: James Lee, Sadaf Mehdizadeh, Jennifer Smith, Arabella Young, Ilgiz A. Mufazalov, Cody T. Mowery, Adil Daud, Jeffrey A. Bluestone - Science Immunology 2020 cited by 300
- CTLA-4 can function as a negative regulator of T cell activation
Authors: Theresa L. Walunas, Deborah J. Lenschow, Christina Y. Bakker, Peter S. Linsley, Gordon J. Freeman, Jonathan M. Green, Craig B. Thompson, Jeffrey A. Bluestone - Immunity 1994 cited by 2,198
- Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
Authors: Jonathan T. Sockolosky, Eleonora Trotta, Giulia Parisi, Lora K. Picton, Leon Su, Alan Le, Akanksha Chhabra, Stephanie Silveria, Benson M. George, Indigo C. King, Matthew Tiffany, Kevin M. Jude, Leah V. Sibener, David Baker, Judith A. Shizuru, Antoni Ribas, Jeffrey A. Bluestone, K. Christopher García - Science 2018 cited by 373
- Control of peripheral T‐cell tolerance and autoimmunity via the CTLA‐4 and PD‐1 pathways
Authors: Brian T. Fife, Jeffrey A. Bluestone - Immunological Reviews 2008 cited by 1,034
- Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
Authors: Xuyu Zhou, Samantha L. Bailey-Bucktrout, Lukas T. Jeker, Cristina Peñaranda, Marc Martínez‐Llordella, Meredith Ashby, Maki Nakayama, Wendy Rosenthal, Jeffrey A. Bluestone - Nature Immunology 2009 cited by 1,339
- CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
Authors: Weihong Liu, Amy Putnam, Zhou Xu-yu, Gregory L. Szot, Michael R. Lee, Shirley Zhu, Peter A. Gottlieb, Philipp Kapranov, T Gingeras, Barbara Fazekas de St Groth, Carol Clayberger, David M. Soper, Steven F. Ziegler, Jeffrey A. Bluestone - The Journal of Experimental Medicine 2006 cited by 2,584
- Innate immunity and intestinal microbiota in the development of Type 1 diabetes
Authors: Wen Li, Ruth E. Ley, Pavel Volchkov, P. Benjamin Stranges, Lia Avanesyan, Austin C. Stonebraker, Changyun Hu, F. Susan Wong, Gregory L. Szot, Jeffrey A. Bluestone, Jeffrey I. Gordon, Alexander V. Chervonsky - Nature 2008 cited by 1,930
- Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials
Authors: Birgit Sawitzki, Paul Harden, Petra Reinke, Aurélie Moreau, James A. Hutchinson, David Game, Qizhi Tang, Eva C. Guinan, Manuela Battaglia, William J. Burlingham, Ian S.D. Roberts, Mathias Streitz, Régis Josien, Carsten A. Böger, Cristiano Scottà, James F. Markmann, Joanna Hester, Karsten Juerchott, Cécile Braudeau, Ben James, Laura Contreras‐Ruiz, Jeroen B. van der Net, Tobias Bergler, Rossana Caldara, William Petchey, Matthias Edinger, Nathalie Dupas, Michael Kapinsky, Ingrid Mutzbauer, Natalie Otto, Robert Öllinger, María P. Hernández-Fuentes, Fadi Issa, Norbert Ahrens, Christoph Meyenberg, Sandra Karitzky, Ulrich Kunzendorf, Stuart J. Knechtle, Josep M. Grinyó, Peter J. Morris, L Brent, Andrew Bushell, Laurence A. Turka, Jeffrey A. Bluestone, Robert I. Lechler, Hans J. Schlitt, María Cristina Cuturi, Stephan Schlickeiser, Peter J. Friend, Tewfik Miloud, Alexander Scheffold, Antonio Secchi, Kerry Crisalli, Sang‐Mo Kang, Rachel Hilton, Bernhard Banas, Gilles Blancho, Hans‐Dieter Volk, Giovanna Lombardi, Kathryn J. Wood, Edward K. Geissler - The Lancet 2020 cited by 451
- Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency
Authors: David N. Nguyen, Theodore L. Roth, P. Jonathan Li, Peixin Amy Chen, Ryan Apathy, Murad R. Mamedov, Linda T. Vo, Victoria Tobin, Daniel B. Goodman, Eric Shifrut, Jeffrey A. Bluestone, Jennifer M. Puck, Francis C. Szoka, Alexander Marson - Nature Biotechnology 2019 cited by 325
- Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19
Authors: Yapeng Su, Daniel Chen, Dan Yuan, Christopher Lausted, Jongchan Choi, Chengzhen L. Dai, Valentin Voillet, Venkata R. Duvvuri, Kelsey Scherler, Pamela Troisch, Priyanka Baloni, Guangrong Qin, Brett Smith, Sergey A. Kornilov, Clifford Rostomily, Alexander M. Xu, Jing Li, Shen Dong, Alissa C. Rothchild, Jing Zhou, Kim M. Murray, Rick Edmark, Sunga Hong, John E. Heath, John C. Earls, Rongyu Zhang, Jingyi Xie, Sarah Li, Ryan Roper, Lesley Jones, Yong Zhou, Lee Rowen, Rachel Liu, Sean Mackay, D. Shane O’Mahony, Christopher Dale, Julie A. Wallick, Heather A. Algren, Michael Zager, Wei Wei, Nathan D. Price, Sui Huang, Naeha Subramanian, Kai Wang, Andrew T. Magis, Jennifer Hadlock, Leroy Hood, Alan Aderem, Jeffrey A. Bluestone, Lewis L. Lanier, Philip D. Greenberg, Raphaël Gottardo, Mark M. Davis, Jason D. Goldman, James R. Heath - Cell 2020 cited by 644
- CRISPR screen in regulatory T cells reveals modulators of Foxp3
Authors: Jessica T. Cortez, Elena Montauti, Eric Shifrut, Jovylyn Gatchalian, Yusi Zhang, Oren Shaked, Yuanming Xu, Theodore L. Roth, Dimitre R. Simeonov, Yana Zhang, Siqi Chen, Zhongmei Li, Jonathan M. Woo, Josephine Ho, Ian Vogel, Grace Y. Prator, Bin Zhang, Youjin Lee, Zhaolin Sun, Igal Ifergan, Frédéric Van Gool, Diana C. Hargreaves, Jeffrey A. Bluestone, Alexander Marson, Deyu Fang - Nature 2020 cited by 236
- The effect of low-dose IL-2 and Treg adoptive cell therapy in patients with type 1 diabetes
Authors: Shen Dong, Kamir J. Hiam-Galvez, Cody T. Mowery, Kevan C. Herold, Stephen E. Gitelman, Jonathan H. Esensten, Weihong Liu, Angela Lares, Ashley Leinbach, Michael Lee, Vinh Nguyen, Stanley Tamaki, Whitney Tamaki, Courtney Tamaki, Morvarid Mehdizadeh, Amy Putnam, Matthew H. Spitzer, Chun Ye, Qizhi Tang, Jeffrey A. Bluestone - JCI Insight 2021 cited by 221
- Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
Authors: Kathrin Schumann, Steven Lin, Eric Boyer, Dimitre R. Simeonov, Meena Subramaniam, Rachel E. Gate, Genevieve Haliburton, Chun Ye, Jeffrey A. Bluestone, Jennifer A. Doudna, Alexander Marson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2015 cited by 723
- Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity
Authors: David Wang, Jason Quiros, Kelly M. Mahuron, Chien-Chun Steven Pai, Valeria Ranzani, Arabella Young, Stephanie Silveria, Tory Harwin, Arbi Abnousian, Massimiliano Pagani, Michael D. Rosenblum, Frédéric Van Gool, Lawrence Fong, Jeffrey A. Bluestone, Michel DuPage - Cell Reports 2018 cited by 310
- Opportunities for Treg cell therapy for the treatment of human disease
Authors: Jeffrey A. Bluestone, Brent S. McKenzie, Joshua Beilke, Fred Ramsdell - Frontiers in Immunology 2023 cited by 124
- In Vitro–expanded Antigen-specific Regulatory T Cells Suppress Autoimmune Diabetes
Authors: Qizhi Tang, Kammi Henriksen, Mingying Bi, Erik B. Finger, Gregory L. Szot, Jianqin Ye, Emma L. Masteller, Hugh O. McDevitt, Mark Bonyhadi, Jeffrey A. Bluestone - The Journal of Experimental Medicine 2004 cited by 1,214
