litlas
Log inCreate account

Igor B. Roninson

Active 1983–2024

85
Papers
20,088
Citations
73
h-index
82
i10-index

Citations

Citations per year for Igor B. Roninson1931: 1 citations1984: 2 citations1985: 9 citations1986: 63 citations1987: 118 citations1988: 115 citations1989: 131 citations1990: 164 citations1991: 122 citations1992: 184 citations1993: 133 citations1994: 111 citations1995: 146 citations1996: 171 citations1997: 114 citations1998: 106 citations1999: 112 citations2000: 137 citations2001: 201 citations2002: 204 citations2003: 226 citations2004: 174 citations2005: 258 citations2006: 185 citations2007: 158 citations2008: 177 citations2009: 114 citations2010: 158 citations2011: 135 citations2012: 147 citations2013: 102 citations2014: 109 citations2015: 83 citations2016: 75 citations2017: 102 citations2018: 86 citations2019: 311 citations2020: 351 citations2021: 364 citations2022: 236 citations2023: 172 citations2024: 277 citations2025: 97 citations2026: 1 citations1932–1983: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,058 citing papers, 33.1% of this breakdownChina: 507 citing papers, 8.2% of this breakdownUnited Kingdom: 341 citing papers, 5.5% of this breakdownGermany: 327 citing papers, 5.3% of this breakdownCanada: 298 citing papers, 4.8% of this breakdownJapan: 280 citing papers, 4.5% of this breakdownNetherlands: 202 citing papers, 3.3% of this breakdownFrance: 199 citing papers, 3.2% of this breakdownItaly: 161 citing papers, 2.6% of this breakdownAustralia: 146 citing papers, 2.3% of this breakdownSwitzerland: 119 citing papers, 1.9% of this breakdownIndia: 114 citing papers, 1.8% of this breakdown
0%33.1%Other 23.5%

Institutions

Fields

  • Medicine58.6%
  • Biochemistry, Genetics and Molecular Biology33.1%
  • Immunology and Microbiology2.1%
  • Materials Science1%
  • Pharmacology, Toxicology and Pharmaceutics1%
  • Agricultural and Biological Sciences1%
  • Other3.2%

Topics

  • Drug Transport and Resistance Mechanisms10.8%
  • Cancer-related Molecular Pathways3.5%
  • Telomeres, Telomerase, and Senescence3.1%
  • Pharmacological Effects and Toxicity Studies2.8%
  • Cancer therapeutics and mechanisms2.4%
  • DNA Repair Mechanisms2.1%
  • Other75.3%

Coauthors

All papers

Open in search
  1. Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

    Authors: Amer Alam, Julia Kowal, Eugenia V. Broude, Igor B. Roninson, Kaspar P. Locher - Science 2019 cited by 471

  2. Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

    Authors: Panagiotis Galanos, Konstantinos Vougas, David Walter, Alexander Polyzos, Apolinar Maya‐Mendoza, Emma J. Haagensen, Antonis Kokkalis, Fani‐Marlen Roumelioti, Sarantis Gagos, Maria Tzetis, Begoña Cánovas, Ana Igea, Akshay K. Ahuja, Ralph Zellweger, Sofia Havaki, Emanuel Kanavakis, Dimitris Kletsas, Igor B. Roninson, Spiros D. Garbis, Massimo Lopes, Ángel R. Nebreda, Dimitris Thanos, J. Julian Blow, Paul A. Townsend, Claus Storgaard Sørensen, Jiří Bártek, Vassilis G. Gorgoulis - Nature Cell Biology 2016 cited by 312

  3. Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene

    Authors: William S. Chen, Pei-Zhang Xu, Kathrin Gottlob, Mei-Ling Chen, Karen Sokol, Tanya Shiyanova, Igor B. Roninson, Wei Weng, Ryo Suzuki, Kazuyuki Tobe, Takashi Kadowaki, Nissim Hay - Genes & Development 2001 cited by 922

  4. CDK8/19 Mediator kinases potentiate induction of transcription by NFκB

    Authors: Mengqian Chen, Jiaxin Liang, Hao Ji, Zhengguan Yang, Serena Altilia, Bing Hu, Adam Schronce, Martina S.J. McDermott, Gary P. Schools, Chang‐Uk Lim, David J. Oliver, Michael Shtutman, Tao Lu, George R. Stark, Donald C. Porter, Eugenia V. Broude, Igor B. Roninson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 cited by 140

  5. Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1

    Authors: Amer Alam, Raphael Küng, Julia Kowal, Robert A. McLeod, Nina Tremp, Eugenia V. Broude, Igor B. Roninson, Henning Stahlberg, Kaspar P. Locher - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 cited by 196

  6. A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents.

    Authors: Bey-Dih Chang, Eugenia V. Broude, Milos Dokmanovic, Hongming Zhu, Adam Ruth, Yongzhi Xuan, Eugene Kandel, Ekkehart Lausch, Konstantin Christov, Igor B. Roninson - 1999 cited by 546

  7. Tumor cell senescence in cancer treatment.

    Authors: Igor B. Roninson - 2003 cited by 608

  8. Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities

    Authors: Donald C. Porter, Elena Farmaki, Serena Altilia, Gary P. Schools, Deborah K. West, Mengqian Chen, Bey-Dih Chang, Anatoliy T. Puzyrev, Chang‐Uk Lim, Rebecca Rokow-Kittell, Lawrence Friedhoff, Athanasios G. Papavassiliou, Swathi Kalurupalle, Gregory J. Hurteau, Jun Shi, Phil S. Baran, Balázs Győrffy, Mark P. Wentland, Eugenia V. Broude, Hippokratis Kiaris, Igor B. Roninson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 cited by 176

  9. CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases

    Authors: Jiaxin Liang, Mengqian Chen, Daniel Hughes, Alexander A. Chumanevich, Serena Altilia, Vimala Kaza, Chang‐Uk Lim, Hippokratis Kiaris, Karthikeyan Mythreye, Maria Marjorette O. Peña, Eugenia V. Broude, Igor B. Roninson - Cancer Research 2018 cited by 89

  10. Effects of p21 Waf1/Cip1/Sdi1 on cellular gene expression: Implications for carcinogenesis, senescence, and age-related diseases

    Authors: Bey-Dih Chang, Keiko Watanabe, Eugenia V. Broude, Jing Fang, Jason C. Poole, T. V. Kalinichenko, Igor B. Roninson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2000 cited by 431

  11. A structural interpretation of the effect of GC-content on efficiency of RNA interference

    Authors: Chi Yu Chan, C. Steven Carmack, Dang D. Long, Anil Maliyekkel, Yu Shao, Igor B. Roninson, Ye Ding - BMC Bioinformatics, BMC Bioinform. 2009 cited by 125

  12. CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins

    Authors: Mengqian Chen, Jing Li, Li Zhang, Lili Wang, Chen Cheng, Hao Ji, Serena Altilia, Xiaokai Ding, Guoshuai Cai, Diego Altomare, Michael Shtutman, Stephanie D. Byrum, Samuel G. Mackintosh, А. В. Феоктистов, Н. В. Сошникова, Vladic Mogila, Victor V. Tatarskiy, Maksim Erokhin, Darya Chetverina, Angga Prawira, Yi Ni, Stephan Urban, Campbell McInnes, Eugenia V. Broude, Igor B. Roninson - Nucleic Acids Research 2023 cited by 67

  13. If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells

    Authors: Igor B. Roninson, Eugenia V. Broude, Bey-Dih Chang - Drug Resistance Updates 2001 cited by 723

  14. Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo

    Authors: Xiaokai Ding, Amanda C. Sharko, Martina S.J. McDermott, Gary P. Schools, Alexander A. Chumanevich, Hao Ji, Jing Li, Li Zhang, Zachary T. Mack, Vitali Sikirzhytski, Michael Shtutman, Laura Ivers, Norma O’Donovan, John Crown, Balázs Győrffy, Mengqian Chen, Igor B. Roninson, Eugenia V. Broude - National Academy of Sciences, Proceedings of the National Academy of Sciences 2022 cited by 52

  15. Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

    Authors: Chang-jie Chen, Janice E. Chin, Kazumitsu Ueda, Douglas P. Clark, Ira Pastan, Michael M. Gottesman, Igor B. Roninson - Cell 1986 cited by 1,916

  16. Hallmarks of senescence in carcinogenesis and cancer therapy

    Authors: Jerry W. Shay, Igor B. Roninson - Oncogene 2004 cited by 496

  17. Oncogenic functions of tumour suppressor p21Waf1/Cip1/Sdi1: association with cell senescence and tumour-promoting activities of stromal fibroblasts

    Authors: Igor B. Roninson - Cancer Letters 2002 cited by 445

  18. Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells.

    Authors: Igor B. Roninson, Janice E. Chin, Kyoung‐Gyu Choi, Piet Gros, David E. Housman, Antonio Tito Fojo, Donglai Shen, Michael M. Gottesman, I Pastan - National Academy of Sciences, Proceedings of the National Academy of Sciences 1986 cited by 703

  19. Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent

    Authors: Bey-Dih Chang, Mari E. Swift, Mei Shen, Jing Fang, Eugenia V. Broude, Igor B. Roninson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2001 cited by 305

  20. Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer

    Authors: Martina S.J. McDermott, Alexander A. Chumanevich, Chang‐Uk Lim, Jiaxin Liang, Mengqian Chen, Serena Altilia, David J. Oliver, James M. Rae, Michael Shtutman, Hippokratis Kiaris, Balázs Győrffy, Igor B. Roninson, Eugenia V. Broude - Oncotarget 2017 cited by 131

  21. A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics

    Authors: Li Zhang, Chen Cheng, Jing Li, Lili Wang, Alexander A. Chumanevich, Donald C. Porter, Aleksei Mindich, S. M. Gorbunova, Igor B. Roninson, Mengqian Chen, Campbell McInnes - Journal of Medicinal Chemistry 2022 cited by 37

  22. Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast Cancer

    Authors: Eugenia V. Broude, Balázs Győrffy, Alexander A. Chumanevich, Mengqian Chen, Martina S.J. McDermott, Michael Shtutman, James F. Catroppo, Igor B. Roninson - Current Cancer Drug Targets 2015 cited by 99

  23. The Inhibition of CDK8/19 Mediator Kinases Prevents the Development of Resistance to EGFR-Targeting Drugs

    Authors: Amanda C. Sharko, Chang‐Uk Lim, Martina S.J. McDermott, Chuck Hennes, Kingsavanh P. Philavong, Tiffanie Aiken, Victor V. Tatarskiy, Igor B. Roninson, Eugenia V. Broude - Cells 2021 cited by 35

  24. The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein

    Authors: Kazumitsu Ueda, Marilyn M. Cornwell, Michael M. Gottesman, Ira Pastan, Igor B. Roninson, Victor Ling, John R. Riordan - Biochemical and Biophysical Research Communications 1986 cited by 413