Michael M. Gottesman
Active 1973–2025
- 186
- Papers
- 63,473
- Citations
- 112
- h-index
- 179
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine51.4%
- Biochemistry, Genetics and Molecular Biology31%
- Materials Science4.8%
- Engineering2.7%
- Pharmacology, Toxicology and Pharmaceutics1.9%
- Immunology and Microbiology1.7%
- Other6.5%
Topics
- Drug Transport and Resistance Mechanisms11.9%
- Pharmacological Effects and Toxicity Studies3.1%
- Nanoparticle-Based Drug Delivery2.8%
- RNA Interference and Gene Delivery2.6%
- Cancer therapeutics and mechanisms2.2%
- HIV/AIDS drug development and treatment1.9%
- Other75.5%
Coauthors
- Ira Pastan71
- Suresh V. Ambudkar35
- Robert W. Robey25
- Matthew D. Hall24
- Carol Cardarelli12
- Gergely Szakács12
- Antonio Tito Fojo11
- Kazumitsu Ueda11
- Chava Kimchi‐Sarfaty10
- I Pastan9
- Igor B. Roninson9
- Ursula A. Germann9
- Jean‐Pierre Gillet8
- Marilyn M. Cornwell8
- Mark C. Willingham8
- Christine A. Hrycyna7
- Ding‐Wu Shen7
- Khew‐Voon Chin7
- Murali Ramachandra7
- Xing‐Jie Liang7
- Zuben E. Sauna7
- Suneet Shukla6
- Donglai Shen5
- Janice E. Chin5
All papers
- Revisiting the role of ABC transporters in multidrug-resistant cancer
Authors: Robert W. Robey, Kristen M. Pluchino, Matthew D. Hall, Antonio Tito Fojo, Susan E. Bates, Michael M. Gottesman - Nature reviews. Cancer 2018 cited by 1,832
- Multidrug resistance in cancer: role of ATP–dependent transporters
Authors: Michael M. Gottesman, Tito Fojo, Susan E. Bates - Nature reviews. Cancer 2002 cited by 5,519
- Targeting multidrug resistance in cancer
Authors: Gergely Szakács, Jill K. Paterson, Joseph A. Ludwig, Catherine Booth-Genthe, Michael M. Gottesman - Nature Reviews Drug Discovery 2006 cited by 3,649
- Mechanisms of Cancer Drug Resistance
Authors: Michael M. Gottesman - Annual Review of Medicine 2002 cited by 2,646
- Cisplatin Resistance: A Cellular Self-Defense Mechanism Resulting from Multiple Epigenetic and Genetic Changes
Authors: Ding‐Wu Shen, Lynn M. Pouliot, Matthew D. Hall, Michael M. Gottesman - Pharmacological Reviews 2012 cited by 972
- P-glycoprotein: from genomics to mechanism
Authors: Suresh V. Ambudkar, Chava Kimchi‐Sarfaty, Zuben E. Sauna, Michael M. Gottesman - Oncogene 2003 cited by 1,061
- A "Silent" Polymorphism in the MDR 1 Gene Changes Substrate Specificity
Authors: Chava Kimchi‐Sarfaty, Jung Mi Oh, In‐Wha Kim, Zuben E. Sauna, Anna Maria Calcagno, Suresh V. Ambudkar, Michael M. Gottesman - Science 2006 cited by 2,478
- Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.
Authors: F Thiébaut, T Tsuruo, Hironobu Hamada, Michael M. Gottesman, I Pastan, Mark C. Willingham - National Academy of Sciences, Proceedings of the National Academy of Sciences 1987 cited by 2,795
- The molecular basis of multidrug resistance in cancer: The early years of P‐glycoprotein research
Authors: Michael M. Gottesman, Victor Ling - FEBS Letters 2005 cited by 549
- Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum Complexes
Authors: Matthew D. Hall, Katherine A. Telma, Ki-Eun Chang, Tobie D. Lee, James P. Madigan, John R. Lloyd, Ian S. Goldlust, James D. Hoeschele, Michael M. Gottesman - Cancer Research 2014 cited by 374
- Drug resistance: Still a daunting challenge to the successful treatment of AML
Authors: Brian C. Shaffer, Jean‐Pierre Gillet, Chirayu Patel, Maria R. Baer, Susan E. Bates, Michael M. Gottesman - Drug Resistance Updates 2012 cited by 265
- BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTER
Authors: Suresh V. Ambudkar, Saibal Dey, Christine A. Hrycyna, Murali Ramachandra, Ira Pastan, Michael M. Gottesman - The Annual Review of Pharmacology and Toxicology 1999 cited by 2,062
- Mechanisms of Multidrug Resistance in Cancer
Authors: Jean‐Pierre Gillet, Michael M. Gottesman - Methods in molecular biology 2009 cited by 687
- Toward a Better Understanding of the Complexity of Cancer Drug Resistance
Authors: Michael M. Gottesman, Orit Lavi, Matthew D. Hall, Jean-Pierre Gillet - The Annual Review of Pharmacology and Toxicology 2015 cited by 329
- Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance
Authors: Jean-Pierre Gillet, Anna Maria Calcagno, Sudhir Varma, Miguel Marino, Lisa J. Green, Meena I. Vora, Chirayu Patel, Josiah N. Orina, Tatiana Eliseeva, Vineet Singal, R. Padmanabhan, Ben Davidson, Ram Ganapathi, Anil K. Sood, Bo R. Rueda, Suresh V. Ambudkar, Michael M. Gottesman - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 474
- Collateral sensitivity as a strategy against cancer multidrug resistance
Authors: Kristen M. Pluchino, Matthew D. Hall, Andrew S. Goldsborough, Richard Callaghan, Michael M. Gottesman - Drug Resistance Updates 2012 cited by 313
- α-Galactosidase A deficient mice: A model of Fabry disease
Authors: Toshio Ohshima, Gary J. Murray, William D. Swaim, Glenn Longenecker, Jane M. Quirk, Carol Cardarelli, Yoshikazu Sugimoto, Ira Pastan, Michael M. Gottesman, Roscoe O. Brady, Ashok B. Kulkarni - National Academy of Sciences, Proceedings of the National Academy of Sciences 1997 cited by 368
- The Role of Multidrug Resistance Efflux Pumps in Cancer: Revisiting a JNCI Publication Exploring Expression of the MDR1 (P-glycoprotein) Gene
Authors: Michael M. Gottesman, Ira Pastan - JNCI Journal of the National Cancer Institute 2015 cited by 147
- Predicting drug sensitivity and resistance
Authors: Gergely Szakács, Jean-Philippe Annereau, Samir Lababidi, Uma Shankavaram, Angela Arciello, Kimberly J. Bussey, William C. Reinhold, Yanping Guo, Gary D. Kruh, Mark Reimers, John N. Weinstein, Michael M. Gottesman - Cancer Cell 2004 cited by 532
- BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER
Authors: Michael M. Gottesman, I Pastan - Annual Review of Biochemistry 1993 cited by 3,505
- The multidrug resistance transporter P-glycoprotein confers resistance to ferroptosis inducers
Authors: William J.E. Frye, Lyn M. Huff, José M. González Dalmasy, Paula Salazar, Rachel M. Carter, Ryan T. Gensler, Dominic Esposito, Robert W. Robey, Suresh V. Ambudkar, Michael M. Gottesman - Cancer Drug Resistance 2023 cited by 20
- The Role of Cellular Accumulation in Determining Sensitivity to Platinum-Based Chemotherapy
Authors: Matthew D. Hall, Mitsunori Okabe, Ding‐Wu Shen, Xing‐Jie Liang, Michael M. Gottesman - The Annual Review of Pharmacology and Toxicology 2007 cited by 475
- Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity
Authors: Lothar Esser, Fei Zhou, Kristen M. Pluchino, Joseph Shiloach, Jichun Ma, Wai-kwan Tang, Camilo Gutierrez, Alex Zhang, Suneet Shukla, James P. Madigan, Tongqing Zhou, Peter D. Kwong, Suresh V. Ambudkar, Michael M. Gottesman, Di Xia - Journal of Biological Chemistry 2016 cited by 181
- Model systems for studying the blood-brain barrier: Applications and challenges
Authors: Sadhana Jackson, Caitlin Meeks, Amélie Vézina, Robert W. Robey, Kandice Tanner, Michael M. Gottesman - Biomaterials 2019 cited by 73
