Jacques Neefjes
Active 1986–2024
- 179
- Papers
- 34,938
- Citations
- 105
- h-index
- 175
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology40.6%
- Medicine29.6%
- Immunology and Microbiology22.4%
- Neuroscience1.6%
- Chemistry1.2%
- Agricultural and Biological Sciences1.2%
- Other3.4%
Topics
- Immunotherapy and Immune Responses7.3%
- Immune Cell Function and Interaction5.2%
- T-cell and B-cell Immunology3.8%
- Cancer Immunotherapy and Biomarkers3.6%
- Cellular transport and secretion3.1%
- Ubiquitin and proteasome pathways2.4%
- Other74.6%
Coauthors
- Lennert Janssen23
- Ilana Berlin21
- Hans Janssen18
- Hidde L. Ploegh14
- Huib Ovaa14
- Marlieke L.M. Jongsma14
- Ruud H. Wijdeven14
- Eric A. Reits13
- Sabina Y. van der Zanden11
- Anne Neisig10
- Frank Momburg10
- Peter A. van Veelen10
- Birol Cabukusta9
- Coenraad Kuijl9
- Cornelis J.M. Melief9
- Herman S. Overkleeft9
- Jimmy J.L.L. Akkermans9
- Rik van der Kant9
- Tom A. Groothuis9
- Günter J. Hämmerling8
- A. Tulp7
- Alexander Griekspoor7
- Dennis P. A. Wander7
- Desirée Verwoerd7
All papers
- Towards a systems understanding of MHC class I and MHC class II antigen presentation
Authors: Jacques Neefjes, Marlieke L.M. Jongsma, Petra Paul, Oddmund Bakke - Nature reviews. Immunology 2011 cited by 1,999
- Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy
Authors: Eric A. Reits, James W. Hodge, Carla Herberts, Tom A. Groothuis, Mala Chakraborty, Elizabeth K. Wansley, Kevin Camphausen, Rosalie M. Luiten, Arnold H. de Ru, Joost Neijssen, Alexander Griekspoor, Elly Mesman, Frank A. W. Verreck, Hergen Spits, Jeffrey Schlom, Peter A. van Veelen, Jacques Neefjes - The Journal of Cell Biology 2006 cited by 1,704
- Present Yourself! By MHC Class I and MHC Class II Molecules
Authors: Kenneth L. Rock, Eric A. Reits, Jacques Neefjes - Trends in Immunology 2016 cited by 794
- New insights into the activities and toxicities of the old anticancer drug doxorubicin
Authors: Sabina Y. van der Zanden, Xiaohang Qiao, Jacques Neefjes - FEBS Journal 2020 cited by 395
- Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling
Authors: Frederik J. Verweij, Maarten P. Bebelman, Connie R. Jiménez, Juan J. García‐Vallejo, Hans Janssen, Jacques Neefjes, Jaco C. Knol, Richard de Goeij-de Haas, Sander R. Piersma, S. Rubina Baglio, Matthijs Verhage, Jaap M. Middeldorp, Anoek Zomer, Jacco van Rheenen, Marc G. Coppolino, Ilse Hurbain, Graça Raposo, Martine J. Smit, Ruud F. Toonen, Guillaume van Niel, D. Michiel Pegtel - The Journal of Cell Biology 2018 cited by 365
- Association of Checkpoint Inhibitor–Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non–Small Cell Lung Cancer
Authors: Fiamma Berner, David Bomze, Stefan Diem, Omar Hasan Ali, Mirjam Fässler, Sandra S. Ring, Rebekka Niederer, Christoph Ackermann, Petra Baumgaertner, Natalia Pikor, Cristina Gil‐Cruz, Willem van de Veen, Mübeccel Akdiş, Sergey I. Nikolaev, Heinz Läubli, Alfred Zippelius, Fabienne Hartmann, Hung‐Wei Cheng, Gideon Hönger, Mike Recher, Jonathan W. Goldman, Antonio Cozzio, Martin Früh, Jacques Neefjes, Christoph Driessen, Burkhard Ludewig, Ahmed N. Hegazy, Wolfram Jochum, Daniel E. Speiser, Lukas Flatz - JAMA Oncology 2019 cited by 393
- Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy
Authors: Meike E. W. Logtenberg, J.H. Marco Jansen, Matthijs Raaben, Mireille Toebes, Katka Franke, Arianne M. Brandsma, Hanke L. Matlung, Astrid Fauster, Raquel Gomez-Eerland, Noor A. M. Bakker, Simone van der Schot, Koen A. Marijt, Martijn Verdoes, John B.A.G. Haanen, Joost H. van den Berg, Jacques Neefjes, Timo K. van den Berg, Thijn R. Brummelkamp, Jeanette H.W. Leusen, Ferenc A. Scheeren, Ton N. Schumacher - Nature Medicine 2019 cited by 242
- Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Glued and late endosome positioning
Authors: Nuno Rocha, Coenraad Kuijl, Rik van der Kant, Lennert Janssen, Diane Houben, Hans Janssen, Wilbert Zwart, Jacques Neefjes - The Journal of Cell Biology 2009 cited by 685
- The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors
Authors: Ingrid Jordens, Mar Fernandez‐Borja, Marije Marsman, Simone Dusseljee, Lennert Janssen, Jero Calafat, Hans Janssen, Richard Wubbolts, Jacques Neefjes - Current Biology 2001 cited by 804
- Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin
Authors: Baoxu Pang, Xiaohang Qiao, Lennert Janssen, Arno Velds, Tom A. Groothuis, Ron Kerkhoven, Marja Nieuwland, Huib Ovaa, Sven Rottenberg, Olaf van Tellingen, Jeroen J. W. M. Janssen, Peter C. Huijgens, Wilbert Zwart, Jacques Neefjes - Nature Communications 2013 cited by 431
- Mechanisms of lysosomal positioning and movement
Authors: Birol Cabukusta, Jacques Neefjes - Traffic 2018 cited by 271
- Moving and positioning the endolysosomal system
Authors: Juan S. Bonifacino, Jacques Neefjes - Current Opinion in Cell Biology 2017 cited by 240
- Anthracyclines: biosynthesis, engineering and clinical applications
Authors: Mandy B. Hulst, Thadée Grocholski, Jacques Neefjes, Gilles P. van Wezel, Mikko Metsä‐Ketelä - Natural Product Reports 2021 cited by 106
- MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor Signaling
Authors: Sidong Huang, Michael Hölzel, Theo Knijnenburg, Andreas Schlicker, Paul Roepman, Ultan McDermott, Mathew J. Garnett, Wipawadee Grernrum, Chong Sun, Anirudh Prahallad, Floris H. Groenendijk, Lorenza Mittempergher, Wouter Nijkamp, Jacques Neefjes, Ramón Salazar, Peter ten Dijke, Hidetaka Uramoto, Fumihiro Tanaka, Roderick L. Beijersbergen, Lodewyk F.A. Wessels, René Bernards - Cell 2012 cited by 434
- On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases
Authors: Reggy Ekkebus, Sander I. van Kasteren, Yogesh Kulathu, Arjen Scholten, Ilana Berlin, Paul P. Geurink, Annemieke de Jong, Soenita S. Goerdayal, Jacques Neefjes, Albert J. R. Heck, David Komander, Huib Ovaa - Journal of the American Chemical Society 2013 cited by 360
- The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses
Authors: Marlieke L.M. Jongsma, Antonius A. de Waard, Matthijs Raaben, Tao Zhang, Birol Cabukusta, René Platzer, Vincent A. Blomen, Anastasia Xagara, Tamara Verkerk, Sophie Bliss, Xiangrui Kong, Carolin Gerke, Lennert Janssen, Elmer Stickel, Stephanie Holst, Rosina Plomp, Arend Mulder, Soldano Ferrone, Frans H.J. Claas, Mirjam H.M. Heemskerk, Marieke Griffioen, Anne Halenius, Hermen Overkleeft, Johannes B. Huppa, Manfred Wuhrer, Thijn R. Brummelkamp, Jacques Neefjes, Robbert M. Spaapen - Immunity 2020 cited by 118
- Uncoupling DNA damage from chromatin damage to detoxify doxorubicin
Authors: Xiaohang Qiao, Sabina Y. van der Zanden, Dennis P. A. Wander, Daniel Borràs, Ji‐Ying Song, Xiaoyang Li, Suzanne van Duikeren, Noortje van Gils, Arjo Rutten, Tessa van Herwaarden, Olaf van Tellingen, Elisa Giacomelli, Milena Bellin, Valeria V. Orlova, Leon G.J. Tertoolen, Sophie Gerhardt, Jimmy J.L.L. Akkermans, Jeroen M. Bakker, Charlotte L. Zuur, Baoxu Pang, Anke M. Smits, Christine L. Mummery, Linda Smit, Ramon Arens, Junmin Li, Herman S. Overkleeft, Jacques Neefjes - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 cited by 168
- SKIP‐HOPS recruits TBC1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport
Authors: Marlieke L.M. Jongsma, Jeroen Bakker, Birol Cabukusta, Nalan Liv, Daphne M. van Elsland, Job Fermie, Jimmy LL Akkermans, Coenraad Kuijl, Sabina Y. van der Zanden, Lennert Janssen, Denise Hoogzaad, Rik van der Kant, Ruud H. Wijdeven, Judith Klumperman, Ilana Berlin, Jacques Neefjes - The EMBO Journal 2020 cited by 113
- Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma
Authors: Tiziana Scanu, Robbert M. Spaapen, Jeroen M. Bakker, Chandra Bhan Pratap, Lin-en Wu, Ingrid Hofland, Annegien Broeks, Vijay K. Shukla, Mohan Kumar, Hans Janßen, Ji‐Ying Song, Andra Neefjes‐Borst, Hein te Riele, David W. Holden, Gopal Nath, Jacques Neefjes - Cell Host & Microbe 2015 cited by 265
- An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport
Authors: Marlieke L.M. Jongsma, Ilana Berlin, Ruud H. Wijdeven, Lennert Janssen, George M.C. Janssen, Malgorzata Garstka, Hans Janßen, Mark Mensink, Peter A. van Veelen, Robbert M. Spaapen, Jacques Neefjes - Cell 2016 cited by 252
- Retrofusion of intralumenal MVB membranes parallels viral infection and coexists with exosome release
Authors: Priscillia Perrin, Lennert Janssen, Hans Janssen, Bram van den Broek, Lennard M. Voortman, Daphne M. van Elsland, Ilana Berlin, Jacques Neefjes - Current Biology 2021 cited by 76
- Variations in MHC Class II Antigen Processing and Presentation in Health and Disease
Authors: Emil R. Unanue, Vito Türk, Jacques Neefjes - Annual Review of Immunology 2016 cited by 278
- Activation of endosomal dynein motors by stepwise assembly of Rab7–RILP–p150Glued, ORP1L, and the receptor βlll spectrin
Authors: Marie Johansson, Nuno Rocha, Wilbert Zwart, Ingrid Jordens, Lennert Janssen, Coenraad Kuijl, Vesa M. Olkkonen, Jacques Neefjes - The Journal of Cell Biology 2007 cited by 485
- Collateral damage: insights into bacterial mechanisms that predispose host cells to cancer
Authors: Aurélie Gagnaire, Bertrand Nadel, Didier Raoult, Jacques Neefjes, Jean‐Pierre Gorvel - Nature Reviews Microbiology 2017 cited by 191
