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James A. Spudich

Active 1963–2025

135
Papers
32,149
Citations
94
h-index
132
i10-index

Citations

Citations per year for James A. Spudich1965: 1 citations1969: 3 citations1970: 3 citations1971: 6 citations1972: 11 citations1973: 20 citations1974: 26 citations1975: 55 citations1976: 61 citations1977: 60 citations1978: 99 citations1979: 94 citations1980: 93 citations1981: 89 citations1982: 84 citations1983: 71 citations1984: 77 citations1985: 84 citations1986: 88 citations1987: 104 citations1988: 89 citations1989: 153 citations1990: 162 citations1991: 134 citations1992: 107 citations1993: 170 citations1994: 191 citations1995: 200 citations1996: 234 citations1997: 230 citations1998: 198 citations1999: 179 citations2000: 261 citations2001: 217 citations2002: 215 citations2003: 181 citations2004: 208 citations2005: 262 citations2006: 183 citations2007: 190 citations2008: 184 citations2009: 166 citations2010: 167 citations2011: 125 citations2012: 129 citations2013: 126 citations2014: 128 citations2015: 144 citations2016: 132 citations2017: 167 citations2018: 178 citations2019: 452 citations2020: 418 citations2021: 470 citations2022: 409 citations2023: 271 citations2024: 583 citations2025: 225 citations2026: 4 citations1966–1968: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,367 citing papers, 44.1% of this breakdownGermany: 698 citing papers, 9.1% of this breakdownUnited Kingdom: 638 citing papers, 8.4% of this breakdownJapan: 393 citing papers, 5.1% of this breakdownFrance: 347 citing papers, 4.5% of this breakdownChina: 318 citing papers, 4.2% of this breakdownItaly: 214 citing papers, 2.8% of this breakdownCanada: 164 citing papers, 2.1% of this breakdownNetherlands: 135 citing papers, 1.8% of this breakdownSwitzerland: 113 citing papers, 1.5% of this breakdownAustralia: 102 citing papers, 1.3% of this breakdownSpain: 88 citing papers, 1.2% of this breakdown
0%44.1%Other 13.9%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology55.2%
  • Medicine30%
  • Physics and Astronomy4.7%
  • Neuroscience2.2%
  • Engineering2.2%
  • Materials Science1.4%
  • Other4.3%

Topics

  • Cardiomyopathy and Myosin Studies10.2%
  • Cellular Mechanics and Interactions9.8%
  • Microtubule and mitosis dynamics4.6%
  • Muscle Physiology and Disorders4.2%
  • Advanced Fluorescence Microscopy Techniques3.5%
  • Force Microscopy Techniques and Applications3.5%
  • Other64.2%

Coauthors

All papers

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  1. A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice

    Authors: Eric M. Green, Hiroko Wakimoto, Robert L. Anderson, Marc Evanchik, Joshua Gorham, Brooke C. Harrison, Marcus Henze, Raja Kawas, Johan D. Oslob, Héctor M. Rodrı́guez, Yonghong Song, William Wan, Leslie A. Leinwand, James A. Spudich, Robert S. McDowell, Jonathan G. Seidman, Christine E. Seidman - Science 2016 cited by 722

  2. Altered Cardiac Energetics and Mitochondrial Dysfunction in Hypertrophic Cardiomyopathy

    Authors: Sara Ranjbarvaziri, Kristina B. Kooiker, Mathew Ellenberger, Giovanni Fajardo, Mingming Zhao, Alison Schroer Vander Roest, Rahel A. Woldeyes, Tiffany T. Koyano, Robyn Fong, Ning Ma, Lei Tian, Gavin M. Traber, Frandics Chan, John Perrino, Sushma Reddy, Wah Chiu, Joseph C. Wu, Joseph Y. Woo, Kathleen M. Ruppel, James A. Spudich, Michael P. Snyder, Kévin Contrepois, Daniel Bernstein - Circulation 2021 cited by 295

  3. Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers

    Authors: Robert L. Anderson, Darshan V. Trivedi, Saswata S. Sarkar, Marcus Henze, Weikang Ma, Henry Gong, Christopher S. Rogers, Joshua Gorham, Fiona L. Wong, Makenna M. Morck, Jonathan G. Seidman, Kathleen M. Ruppel, Thomas C. Irving, Roger Cooke, Eric M. Green, James A. Spudich - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 cited by 408

  4. A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division

    Authors: Uri Manor, Sadie R. Bartholomew, Gonen Golani, Eric T. Christenson, Michael M. Kozlov, Henry N. Higgs, James A. Spudich, Jennifer Lippincott‐Schwartz - eLife 2015 cited by 349

  5. The Regulation of Rabbit Skeletal Muscle Contraction

    Authors: James A. Spudich, Susan Watt - Journal of Biological Chemistry 1971 cited by 4,530

  6. Single myosin molecule mechanics: piconewton forces and nanometre steps

    Authors: Jeffrey T. Finer, Robert Simmons, James A. Spudich - Nature 1994 cited by 1,954

  7. Three perspectives on the molecular basis of hypercontractility caused by hypertrophic cardiomyopathy mutations

    Authors: James A. Spudich - Pflügers Archiv - European Journal of Physiology 2019 cited by 190

  8. Optimized localization analysis for single-molecule tracking and super-resolution microscopy

    Authors: Kim I. Mortensen, L. Stirling Churchman, James A. Spudich, Henrik Flyvbjerg - Nature Methods 2010 cited by 892

  9. The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations

    Authors: Suman Nag, Darshan V. Trivedi, Saswata S. Sarkar, Arjun S. Adhikari, Margaret S. Sunitha, Shirley Sutton, Kathleen M. Ruppel, James A. Spudich - Nature Structural & Molecular Biology 2017 cited by 233

  10. Mavacamten, a precision medicine for hypertrophic cardiomyopathy: From a motor protein to patients

    Authors: Suman Nag, Sampath K. Gollapudi, Carlos del Río, James A. Spudich, Robert McDowell - Science Advances 2023 cited by 75

  11. Cryo-EM structure of the folded-back state of human β-cardiac myosin

    Authors: Alessandro Grinzato, Daniel Auguin, Carlos Kikuti, Neha Nandwani, Dihia Moussaoui, Divya Pathak, Eaazhisai Kandiah, Kathleen M. Ruppel, James A. Spudich, Anne Houdusse, Julien Robert‐Paganin - Nature Communications 2023 cited by 70

  12. Hypertrophic cardiomyopathy: Mutations to mechanisms to therapies

    Authors: Masataka Kawana, James A. Spudich, Kathleen M. Ruppel - Frontiers in Physiology 2022 cited by 56

  13. The myosin swinging cross-bridge model

    Authors: James A. Spudich - Nature Reviews Molecular Cell Biology 2001 cited by 335

  14. SETD3 is an actin histidine methyltransferase that prevents primary dystocia

    Authors: Alex W. Wilkinson, Jonathan Diep, Shaobo Dai, Shuo Liu, Yaw Shin Ooi, Dan Song, Tie‐Mei Li, J.R. Horton, Xing Zhang, Chao Liu, Darshan V. Trivedi, Katherine M. Ruppel, José G. Vilches-Moure, Kerriann M. Casey, Justin Mak, Tina M. Cowan, Joshua E. Elias, Claude M. Nagamine, James A. Spudich, Xiaodong Cheng, Jan E. Carette, Or Gozani - Nature 2018 cited by 172

  15. Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super relaxed state

    Authors: Alison Schroer Vander Roest, Chao Liu, Makenna M. Morck, Kristina B. Kooiker, Gwanghyun Jung, Dan Song, Aminah Dawood, Arnav Jhingran, Gaspard Pardon, Sara Ranjbarvaziri, Giovanni Fajardo, Mingming Zhao, Kenneth S. Campbell, Beth L. Pruitt, James A. Spudich, Kathleen M. Ruppel, Daniel Bernstein - National Academy of Sciences, Proceedings of the National Academy of Sciences 2021 cited by 82

  16. The myosin superfamily at a glance

    Authors: M. Amanda Hartman, James A. Spudich - Journal of Cell Science 2012 cited by 328

  17. The hypertrophic cardiomyopathy mutations R403Q and R663H increase the number of myosin heads available to interact with actin

    Authors: Saswata S. Sarkar, Darshan V. Trivedi, Makenna M. Morck, Arjun S. Adhikari, Shaik Pasha, Kathleen M. Ruppel, James A. Spudich - Science Advances 2020 cited by 100

  18. Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human β-cardiac myosin motor function

    Authors: Ruth F. Sommese, Jongmin Sung, Suman Nag, Shirley Sutton, John C. Deacon, Elizabeth Choe, Leslie A. Leinwand, Kathleen M. Ruppel, James A. Spudich - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 181

  19. Hypertrophic cardiomyopathy and the myosin mesa: viewing an old disease in a new light

    Authors: Darshan V. Trivedi, Arjun S. Adhikari, Saswata S. Sarkar, Kathleen M. Ruppel, James A. Spudich - Biophysical Reviews 2017 cited by 161

  20. The myosin mesa and a possible unifying hypothesis for the molecular basis of human hypertrophic cardiomyopathy

    Authors: James A. Spudich - Biochemical Society Transactions 2015 cited by 151

  21. Myosin-V is a processive actin-based motor

    Authors: Amit Mehta, Ronald S. Rock, Matthias Rief, James A. Spudich, Mark S. Mooseker, Richard E. Cheney - Nature 1999 cited by 800

  22. β-Cardiac myosin hypertrophic cardiomyopathy mutations release sequestered heads and increase enzymatic activity

    Authors: Arjun S. Adhikari, Darshan V. Trivedi, Saswata S. Sarkar, Dan Song, Kristina B. Kooiker, Daniel Bernstein, James A. Spudich, Kathleen M. Ruppel - Nature Communications 2019 cited by 90

  23. Myosin step size

    Authors: Taro Q.P. Uyeda, Stephen J. Kron, James A. Spudich - Journal of Molecular Biology 1990 cited by 461

  24. Multidimensional structure-function relationships in human β-cardiac myosin from population-scale genetic variation

    Authors: Julian R. Homburger, Eric M. Green, Colleen Caleshu, Margaret S. Sunitha, R. E. Taylor, Kathleen M. Ruppel, Raghu Metpally, Steven D. Colan, Michelle Michels, Sharlene M. Day, Iacopo Olivotto, Carlos D. Bustamante, Frederick E. Dewey, Carolyn Y. Ho, James A. Spudich, Euan A. Ashley - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 130