James N. Ihle
Active 1969–2015
- 138
- Papers
- 43,908
- Citations
- 111
- h-index
- 138
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine49.8%
- Biochemistry, Genetics and Molecular Biology23.5%
- Immunology and Microbiology21.6%
- Neuroscience2.8%
- Agricultural and Biological Sciences0.8%
- Pharmacology, Toxicology and Pharmaceutics0.4%
- Other1.1%
Topics
- Cytokine Signaling Pathways and Interactions10.1%
- Immune Cell Function and Interaction5.7%
- T-cell and B-cell Immunology3.9%
- Immune Response and Inflammation2.6%
- interferon and immune responses2.4%
- NF-κB Signaling Pathways1.8%
- Other73.5%
Coauthors
- Bruce A. Witthuhn19
- Evan Parganas16
- Frederick W. Quelle15
- Demin Wang13
- Olli Silvennoinen13
- John L. Cleveland12
- William E. Thierfelder11
- Catriona McKay8
- Jian Feng7
- Richard Moriggl7
- Angelika Hoffmeyer6
- Dimitrios J. Stravopodis6
- Gerard C. Grosveld6
- Ian M. Kerr6
- Jean‐Christophe Marine6
- Nick Carpino6
- Roland P. Piekorz6
- Taolin Yi6
- David J. Topham5
- George R. Stark5
- Hideaki Nakajima5
- Kevin D. Bunting5
- Mark Y. Sangster5
- Osamu Miura5
All papers
- c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression
Authors: Troy A. Baudino, Catriona McKay, Hélène Pendeville-Samain, Jonas A. Nilsson, Kirsteen H. Maclean, Elsie White, Ann C. Davis, James N. Ihle, John L. Cleveland - Genes & Development 2002 cited by 535
- Functional Activation of Jak1 and Jak3 by Selective Association with IL-2 Receptor Subunits
Authors: Tadaaki Miyazaki, Atsuo Kawahara, Hodaka Fujii, Yoko Nakagawa, Yasuhiro Minami, Zhaojun Liu, Isao Oishi, Olli Silvennoinen, Bruce A. Witthuhn, James N. Ihle, Tadatsugu Taniguchi - Science 1994 cited by 594
- Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
Authors: Kazuya Shimoda, Jan van Deursent, Mark Y. Sangster, Sally R. Sarawar, Richard T. Carson, Ralph A. Tripp, Charles C. Chu, Frederick W. Quelle, Tetsuya Nosaka, Dario A.A. Vignali, Peter C. Doherty, Gerard C. Grosveld, W E Paul, James N. Ihle - Nature 1996 cited by 1,297
- Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
Authors: William E. Thierfelder, Jan M. van Deursen, Koh Yamamoto, Ralph A. Tripp, Sally R. Sarawar, Richard T. Carson, Mark Y. Sangster, Dario A.A. Vignali, Peter C. Doherty, Gerard C. Grosveld, James N. Ihle - Nature 1996 cited by 1,185
- Puma is an essential mediator of p53-dependent and -independent apoptotic pathways
Authors: John Jeffers, Evan Parganas, Youngsoo Lee, Chunying Yang, Jinling Wang, Jennifer Brennan, Kirsteen H. Maclean, Jiawen Han, Thomas W. Chittenden, James N. Ihle, Peter J. McKinnon, John L. Cleveland, Gerard P. Zambetti - Cancer Cell 2003 cited by 872
- Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1
Authors: Sean A. Diehl, Juan Anguíta, Angelika Hoffmeyer, Tyler Zapton, James N. Ihle, Erol Fikrig, Mercedes Rincón - Immunity 2000 cited by 403
- Association and Activation of Jak-Tyk Kinases by CNTF-LIF-OSM-IL-6 β Receptor Components
Authors: Neil Stahl, Teri G. Boulton, Thomas J. Farruggella, Nancy Y. Ip, Sam Davis, Bruce A. Witthuhn, Frederick W. Quelle, Olli Silvennoinen, Giovanna Barbieri, Sandra Pellegrini, James N. Ihle, George D. Yancopoulos - Science 1994 cited by 983
- The Stat family in cytokine signaling
Authors: James N. Ihle - Current Opinion in Cell Biology 2001 cited by 720
- Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons
Authors: Jyh-Rong Chao, Evan Parganas, Kelli L. Boyd, Cheol Yi Hong, Joseph T. Opferman, James N. Ihle - Nature 2008 cited by 253
- Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors
Authors: Evan Parganas, Demin Wang, Dimitrios J. Stravopodis, David J. Topham, Jean‐Christophe Marine, Stephan Teglund, Elio F. Vanin, Sara M. Bodner, Oscar R. Colamonici, Jan M. van Deursen, Gerard C. Grosveld, James N. Ihle - Cell 1998 cited by 1,159
- Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses
Authors: Stephan Teglund, Catriona McKay, Erin G. Schuetz, Jan M. van Deursen, Dimitrios J. Stravopodis, Demin Wang, Michael P. Brown, Sara M. Bodner, Gerard C. Grosveld, James N. Ihle - Cell 1998 cited by 1,291
- Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells
Authors: Richard Moriggl, David J. Topham, Stephan Teglund, Veronika Sexl, Catriona McKay, Demin Wang, Angelika Hoffmeyer, Jan van Deursen, Mark Y. Sangster, Kevin D. Bunting, Gerard C. Grosveld, James N. Ihle - Immunity 1999 cited by 554
- JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin
Authors: Bruce A. Witthuhn, Frederick W. Quelle, Olli Silvennoinen, Taolin Yi, Bo Tang, Osamu Miura, James N. Ihle - Cell 1993 cited by 1,223
- The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction
Authors: Mathias Müller, James Briscoe, Carl Laxton, Dmitry Guschin, Andrew Ziemiecki, Olli Silvennoinen, Ailsa G. Harpur, Giovanna Barbieri, Bruce A. Witthuhn, Chris Schindler, Sandra Pellegrini, Andrew F. Wilks, James N. Ihle, George R. Stark, lan M. Kerr - Nature 1993 cited by 771
- The JAK‐binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop
Authors: Hideo Yasukawa, Hiroyuki Misawa, Hiroshi Sakamoto, Masaaki Masuhara, Atsuo Sasaki, Toru Wakioka, Satoshi Ohtsuka, Tsutomu Imaizumi, Tadashi Matsuda, James N. Ihle, Akihiko Yoshimura - The EMBO Journal 1999 cited by 722
- Interferon-induced nuclear signalling by Jak protein tyrosine kinases
Authors: Olli Silvennoinen, James N. Ihle, Joseph Schlessinger, David E. Levy - Nature 1993 cited by 379
- SOCS3 regulates the plasticity of gp130 signaling
Authors: Roland Lang, Anne‐Laure Pauleau, Evan Parganas, Yutaka Takahashi, Jörg Mages, James N. Ihle, Robert Rutschman, Peter J. Murray - Nature Immunology 2003 cited by 436
- Cutting Edge: Stat6-Dependent Substrate Depletion Regulates Nitric Oxide Production
Authors: Robert Rutschman, Roland Lang, Matthias Hesse, James N. Ihle, Thomas A. Wynn, Peter J. Murray - The Journal of Immunology 2001 cited by 318
- Defective Lymphoid Development in Mice Lacking Jak3
Authors: Tetsuya Nosaka, Jan M. A. van Deursen, Ralph A. Tripp, William E. Thierfelder, Bruce A. Witthuhn, Anthony McMickle, Peter C. Doherty, Gerard C. Grosveld, James N. Ihle - Science 1995 cited by 650
- STATs: Signal Transducers and Activators of Transcription
Authors: James N. Ihle - Cell 1996 cited by 1,405
- Jaks and Stats in signaling by the cytokine receptor superfamily
Authors: James N. Ihle, Ian M. Kerr - Trends in Genetics 1995 cited by 905
- SOCS1 Deficiency Causes a Lymphocyte-Dependent Perinatal Lethality
Authors: Jean‐Christophe Marine, David J. Topham, Catriona McKay, Demin Wang, Evan Parganas, Dimitrios J. Stravopodis, Akihiko Yoshimura, James N. Ihle - Cell 1999 cited by 518
- Ars2 Links the Nuclear Cap-Binding Complex to RNA Interference and Cell Proliferation
Authors: Joshua J. Gruber, Douglas S. Zatechka, Leah R. Sabin, Jeongsik Yong, Julian J. Lum, Mei Kong, Wei‐Xing Zong, Zhenxi Zhang, Chi-Kong Lau, Jason S Rawlings, Sara Cherry, James N. Ihle, Gideon Dreyfuss, Craig B. Thompson - Cell 2009 cited by 202
- Distribution of the Mammalian Stat Gene Family in Mouse Chromosomes
Authors: Neal G. Copeland, Debra J. Gilbert, Chris Schindler, Zhong Zhong, Zilong Wen, James Darnell, Alice Mui, Atsushi Miyajima, Frederick W. Quelle, James N. Ihle, Nancy A. Jenkins - Genomics 1995 cited by 195
