John A. Tainer
Active 1975–2025
- 251
- Papers
- 50,231
- Citations
- 127
- h-index
- 246
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology56.3%
- Medicine21.2%
- Immunology and Microbiology4%
- Materials Science3.1%
- Agricultural and Biological Sciences3%
- Chemistry2.6%
- Other9.8%
Topics
- DNA Repair Mechanisms7.4%
- RNA and protein synthesis mechanisms2.7%
- Protein Structure and Dynamics2.6%
- DNA and Nucleic Acid Chemistry2.5%
- CRISPR and Genetic Engineering2.5%
- Enzyme Structure and Function2.4%
- Other79.9%
Coauthors
- Elizabeth D. Getzoff43
- A.S. Arvai31
- Michal Hammel27
- Susan E. Tsutakawa23
- Albino Bacolla19
- Clifford D. Mol19
- Susan P. Lees‐Miller14
- Chi-Lin Tsai13
- Greg L. Hura13
- David Shin11
- Ivaylo Ivanov11
- Robert A. Hallewell11
- Robert P. Rambo11
- David J. Hosfield10
- Davide Moiani10
- Zamal Ahmed10
- Zu Ye10
- Christopher D. Putnam9
- E.D. Getzoff9
- Miaw-Sheue Tsai9
- Richard A. Lerner9
- Aleem Syed8
- Brian R. Crane8
- Hans E. Parge8
All papers
- PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis
Authors: Junwei Hou, Rongce Zhao, Weiya Xia, Chiung-Wen Chang, Yun You, Jung-Mao Hsu, Lei Nie, Yeh Chen, Yu-Chuan Wang, Chunxiao Liu, Wei‐Jan Wang, Yun Wu, Baozhen Ke, Jennifer L. Hsu, Ke-Bin Huang, Zu Ye, Yi Yang, Xianghou Xia, Yintao Li, Chia‐Wei Li, Bin Shao, John A. Tainer, Mien‐Chie Hung - Nature Cell Biology 2020 cited by 1,009
- A first-in-class polymerase theta inhibitor selectively targets homologous-recombination-deficient tumors
Authors: Jia Zhou, Camille Gelot, Constantia Pantelidou, Adam Y. Li, Hatice Yücel, Rachel E. Davis, Anniina Färkkilä, Bose Kochupurakkal, Aleem Syed, Geoffrey I. Shapiro, John A. Tainer, Brian S. J. Blagg, Raphaël Ceccaldi, Alan D. D’Andrea - Nature Cancer 2021 cited by 337
- FoXS, FoXSDock and MultiFoXS: Single-state and multi-state structural modeling of proteins and their complexes based on SAXS profiles
Authors: Dina Schneidman-Duhovny, Michal Hammel, John A. Tainer, Andrej Sali - Nucleic Acids Research, Nucleic Acids Res. 2016 cited by 561
- DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination
Authors: Clifford D. Mol, Tadahide Izumi, Sankar Mitra, John A. Tainer - Nature 2000 cited by 763
- Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1
Authors: Xiangliang Yuan, Yimin Duan, Yi Xiao, Kai Sun, Yutao Qi, Yuan Zhang, Zamal Ahmed, Davide Moiani, Jun Yao, Hongzhong Li, Lin Zhang, Arseniy E. Yuzhalin, Ping Li, Chen‐Yu Zhang, Akosua Badu-Nkansah, Yohei Saito, Xiang-hua Liu, Wen‐Ling Kuo, Haoqiang Ying, Shao‐Cong Sun, Jenny C. Chang, John A. Tainer, Dihua Yu - Cancer Discovery 2022 cited by 125
- The structural biochemistry of the superoxide dismutases
Authors: J. Jefferson P. Perry, David Shin, E.D. Getzoff, John A. Tainer - Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2009 cited by 561
- The MRE11–RAD50–NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair
Authors: Aleem Syed, John A. Tainer - Annual Review of Biochemistry 2018 cited by 398
- Accurate SAXS Profile Computation and its Assessment by Contrast Variation Experiments
Authors: Dina Schneidman‐Duhovny, Michal Hammel, John A. Tainer, Andrej Šali - Biophysical Journal 2013 cited by 602
- MacroBac: New Technologies for Robust and Efficient Large-Scale Production of Recombinant Multiprotein Complexes
Authors: Scott Gradia, Justin P. Ishida, Miaw-Sheue Tsai, Chris Jeans, John A. Tainer, Jill O. Fuss - Methods in enzymology on CD-ROM/Methods in enzymology 2017 cited by 143
- Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN
Authors: Julian Stingele, Roberto Bellelli, Ferdinand Alte, Graeme Hewitt, Grzegorz Sarek, Sarah Maslen, Susan E. Tsutakawa, Annabel Borg, Svend Kjær, John A. Tainer, Mark Skehel, M. Groll, Simon J. Boulton - Molecular Cell 2016 cited by 248
- Exploring the repeat protein universe through computational protein design
Authors: T. J. Brunette, Fabio Parmeggiani, Po-Ssu Huang, Gira Bhabha, Damian C. Ekiert, Susan E. Tsutakawa, Greg L. Hura, John A. Tainer, David Baker - Nature, Nat. 2015 cited by 279
- DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
Authors: Atsushi Shibata, Davide Moiani, A.S. Arvai, J. Jefferson P. Perry, Shane M. Harding, Marie‐Michelle Genois, Ranjan Maity, Sari van Rossum-Fikkert, Aryandi Kertokalio, F Romoli, M. Ismail, Ermal Ismalaj, Elena Petricci, Matthew J. Neale, Robert G. Bristow, Jean‐Yves Masson, Claire Wyman, Penny A. Jeggo, John A. Tainer - Molecular Cell 2013 cited by 567
- Type IV pilus structure and bacterial pathogenicity
Authors: Lisa Craig, Michael E. Pique, John A. Tainer - Nature Reviews Microbiology 2004 cited by 761
- Accurate assessment of mass, models and resolution by small-angle scattering
Authors: Robert P. Rambo, John A. Tainer - Nature 2013 cited by 784
- Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology
Authors: Chris A. Brosey, John A. Tainer - Current Opinion in Structural Biology 2019 cited by 192
- X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution
Authors: Christopher D. Putnam, Michal Hammel, Greg L. Hura, John A. Tainer - Quarterly Reviews of Biophysics 2007 cited by 1,187
- Active and inhibited human catalase structures: ligand and NADPH binding and catalytic mechanism 1 1Edited by R. Huber
Authors: Christopher D. Putnam, A.S. Arvai, Yves Bourne, John A. Tainer - Journal of Molecular Biology 2000 cited by 485
- Amyotrophic Lateral Ssclerosis and Structural Defects in Cu,Zn Superoxide Dismutase
Authors: Han‐Xiang Deng, Afif Hentati, John A. Tainer, Zafar Iqbal, Annarueber Cayabyab, Wu-Yen Hung, Elizabeth D. Getzoff, Ping Hu, Brian Herzfeldt, Raymond P. Roos, Carolyn L. Warner, Gang Deng, Edwin Soriano, Celestine Smyth, Hans E. Parge, Aftab Ahmed, Allen D. Roses, Robert A. Hallewell, Margaret A. Pericak‐Vance, Teepu Siddique - Science 1993 cited by 1,478
- Structural Biology of Rad50 ATPase
Authors: Karl‐Peter Hopfner, Annette Kärcher, David Shin, Lisa Craig, L. Matthew Arthur, James P. Carney, John A. Tainer - Cell 2000 cited by 915
- Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source
Authors: Scott Classen, Greg L. Hura, James M. Holton, Robert P. Rambo, Ivan Rodic, Patrick J. McGuire, Kevin Dyer, Michal Hammel, G. Meigs, Kenneth A. Frankel, John A. Tainer - Journal of Applied Crystallography 2013 cited by 259
- 2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update
Authors: Jill Trewhella, Anthony P. Duff, Dominique Durand, Frank Gabel, J.M. Guss, Wayne A. Hendrickson, Greg L. Hura, David A. Jacques, Nigel Kirby, Ann H. Kwan, Javier Pérez, Lois Pollack, Timothy J. Ryan, Andrej Šali, Dina Schneidman‐Duhovny, Torsten Schwede, Dmitri I. Svergun, Masaaki Sugiyama, John A. Tainer, Patrice Vachette, John Westbrook, Andrew E. Whitten - Acta Crystallographica Section D Structural Biology 2017 cited by 287
- High-Throughput SAXS for the Characterization of Biomolecules in Solution: A Practical Approach
Authors: Kevin Dyer, Michal Hammel, Robert P. Rambo, Susan E. Tsutakawa, Ivan Rodic, Scott Classen, John A. Tainer, Greg L. Hura - Methods in molecular biology 2013 cited by 226
- HU multimerization shift controls nucleoid compaction
Authors: Michal Hammel, Amlanjyoti Dhar, F.E. Reyes, Jian Hua Chen, Rochelle Parpana, Henry Y. H. Tang, Carolyn A. Larabell, John A. Tainer, Sankar Adhya - Science Advances 2016 cited by 189
- Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death
Authors: Jerry H. Houl, Zu Ye, Chris A. Brosey, L.P.F. Balapiti-Modarage, Sarita Namjoshi, Albino Bacolla, Daniel J. Laverty, Brian L. Walker, Yasin Pourfarjam, L.S. Warden, Naga Babu Chinnam, Davide Moiani, Roderick A. Stegeman, Mei‐Kuang Chen, Mien‐Chie Hung, Zachary D. Nagel, Tom Ellenberger, In‐Kwon Kim, Darin E. Jones, Zamal Ahmed, John A. Tainer - Nature Communications 2019 cited by 132
