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John H. Griffin

Active 1976–2025

145
Papers
22,779
Citations
95
h-index
143
i10-index

Citations

Citations per year for John H. Griffin1976: 1 citations1977: 11 citations1978: 20 citations1979: 30 citations1980: 42 citations1981: 28 citations1982: 70 citations1983: 62 citations1984: 72 citations1985: 72 citations1986: 79 citations1987: 65 citations1988: 87 citations1989: 87 citations1990: 73 citations1991: 86 citations1992: 86 citations1993: 84 citations1994: 90 citations1995: 131 citations1996: 92 citations1997: 151 citations1998: 88 citations1999: 105 citations2000: 121 citations2001: 120 citations2002: 96 citations2003: 142 citations2004: 146 citations2005: 142 citations2006: 117 citations2007: 158 citations2008: 155 citations2009: 192 citations2010: 164 citations2011: 192 citations2012: 154 citations2013: 127 citations2014: 112 citations2015: 130 citations2016: 120 citations2017: 114 citations2018: 112 citations2019: 341 citations2020: 341 citations2021: 307 citations2022: 317 citations2023: 197 citations2024: 326 citations2025: 133 citations2026: 1 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,008 citing papers, 36.4% of this breakdownChina: 379 citing papers, 6.9% of this breakdownUnited Kingdom: 320 citing papers, 5.8% of this breakdownGermany: 299 citing papers, 5.4% of this breakdownNetherlands: 286 citing papers, 5.2% of this breakdownCanada: 207 citing papers, 3.8% of this breakdownFrance: 206 citing papers, 3.7% of this breakdownItaly: 188 citing papers, 3.4% of this breakdownJapan: 163 citing papers, 3% of this breakdownAustralia: 144 citing papers, 2.6% of this breakdownSweden: 140 citing papers, 2.5% of this breakdownSwitzerland: 98 citing papers, 1.8% of this breakdown
0%36.4%Other 19.5%

Institutions

Fields

  • Medicine66%
  • Biochemistry, Genetics and Molecular Biology18.3%
  • Neuroscience5.7%
  • Immunology and Microbiology5.5%
  • Engineering1%
  • Nursing0.9%
  • Other2.6%

Topics

  • Blood Coagulation and Thrombosis Mechanisms11.7%
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema5.2%
  • Venous Thromboembolism Diagnosis and Management3.3%
  • Hemophilia Treatment and Research2.8%
  • Platelet Disorders and Treatments2.3%
  • Protease and Inhibitor Mechanisms2.2%
  • Other72.5%

Coauthors

All papers

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  1. Understanding COVID-19-associated coagulopathy

    Authors: Edward M. Conway, Nigel Mackman, Ronald Q. Warren, Alisa S. Wolberg, Laurent O. Mosnier, Robert A. Campbell, Lisa E. Gralinski, Matthew T. Rondina, Frank L. van de Veerdonk, Karin M. Hoffmeister, John H. Griffin, Diane J. Nugent, Kyung D. Moon, James H. Morrissey - Nature reviews. Immunology 2022 cited by 359

  2. Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression

    Authors: Moh’d Mohanad Al‐Dabet, Khurrum Shahzad, Ahmed Elwakiel, Alba Sulaj, Stefan Kopf, Fabian Bock, Ihsan Gadi, Silke Zimmermann, Rajiv Rana, Shruthi Krishnan, Dheerendra Gupta, Jayakumar Manoharan, Sameen Fatima, Sumra Nazir, Constantin Schwab, Ronny Baber, Markus Scholz, Robert Geffers, Peter R. Mertens, Peter P. Nawroth, John H. Griffin, Maria Keller, Chris Dockendorff, Shrey Kohli, Berend Isermann - Nature Communications 2022 cited by 78

  3. Blood–spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice

    Authors: Ethan A. Winkler, Jesse D. Sengillo, Abhay P. Sagare, Zhen Zhao, Qingyi Ma, Edward Zúñiga, Yaoming Wang, Zhihui Zhong, John S. Sullivan, John H. Griffin, Don W. Cleveland, Berislav V. Zloković - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 238

  4. Activated protein C inhibits neutrophil extracellular trap formation in vitro and activation in vivo

    Authors: Laura D. Healy, Cristina Puy, José A. Fernández, Annachiara Mitrugno, Ravi S. Keshari, Nyiawung A. Taku, Tiffany T. Chu, Xiao Xu, András Gruber, Florea Lupu, John H. Griffin, Owen J. T. McCarty - Journal of Biological Chemistry 2017 cited by 110

  5. Final Results of the RHAPSODY Trial: A Multi‐Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A‐APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activator, Mechanical Thrombectomy or both in Moderate to Severe Acute Ischemic Stroke

    Authors: Patrick D. Lyden, Kent E. Pryor, Christopher S. Coffey, Merit Cudkowicz, Robin Conwit, Ashutosh P. Jadhav, Robert N. Sawyer, Jan Claassen, Opeolu Adeoye, Shlee Song, Peter Hannon, Natalia S. Rost, Archana Hinduja, Michel Torbey, Jin‐Moo Lee, Curtis Benesch, Michael Rippee, Marilyn M. Rymer, Michael T. Froehler, E. Clarke Haley, Mark D. Johnson, Jon Yankey, Kim Magee, Julie C. Qidwai, Howard Levy, E. Mark Haacke, Miller Fawaz, Thomas P. Davis, Arthur W. Toga, John H. Griffin, Berislav V. Zloković - Annals of Neurology 2018 cited by 142

  6. The cytoprotective protein C pathway

    Authors: Laurent O. Mosnier, Berislav V. Zloković, John H. Griffin - Blood 2006 cited by 749

  7. Endothelial and Antithrombotic Actions of HDL

    Authors: Chieko Mineo, Hiroshi Deguchi, John H. Griffin, Philip W. Shaul - Circulation Research 2006 cited by 642

  8. Activated protein C, protease activated receptor 1, and neuroprotection

    Authors: John H. Griffin, Berislav V. Zloković, Laurent O. Mosnier - Blood 2018 cited by 128

  9. Cytoprotective activated protein C averts Nlrp3 inflammasome–induced ischemia-reperfusion injury via mTORC1 inhibition

    Authors: Sumra Nazir, Ihsan Gadi, Moh’d Mohanad Al‐Dabet, Ahmed Elwakiel, Shrey Kohli, Sanchita Ghosh, Jayakumar Manoharan, Satish Ranjan, Fabian Bock, Ruediger C. Braun‐Dullaeus, Charles T. Esmon, Tobias B. Huber, Eric Camerer, Chris Dockendorff, John H. Griffin, Berend Isermann, Khurrum Shahzad - Blood 2017 cited by 161

  10. Activated protein C

    Authors: John H. Griffin, José A. Fernández, Andrew J. Gale, Laurent O. Mosnier - Journal of Thrombosis and Haemostasis 2007 cited by 238

  11. Activated protein C: biased for translation

    Authors: John H. Griffin, Berislav V. Zloković, Laurent O. Mosnier - Blood 2015 cited by 258

  12. Tissue factor pathway inhibitor primes monocytes for antiphospholipid antibody-induced thrombosis

    Authors: Nadine Müller‐Calleja, Anne Hollerbach, Svenja Ritter, Denise Pedrosa, Dennis Strand, Claudine Graf, Christoph Reinhardt, Susanne Strand, Philippe Poncelet, John H. Griffin, Karl J. Lackner, Wolfram Ruf - Blood 2019 cited by 65

  13. Factor VIIa induces extracellular vesicles from the endothelium: a potential mechanism for its hemostatic effect

    Authors: Kaushik Das, Shiva Keshava, Shabbir A. Ansari, Vijay Kondreddy, Charles T. Esmon, John H. Griffin, Usha R. Pendurthi, L. Vijaya Mohan Rao - Blood 2021 cited by 43

  14. Deficiency of protein C in congenital thrombotic disease.

    Authors: John H. Griffin, B. L. Evatt, T S Zimmerman, Alice J. Kleiss, Carol S. Wideman - Journal of Clinical Investigation 1981 cited by 1,255

  15. EPCR-dependent PAR2 activation by the blood coagulation initiation complex regulates LPS-triggered interferon responses in mice

    Authors: Hai Liang, E. J. Kerschen, Irene Hernández, Sreemanti Basu, Mark Zogg, Fady Botros, Shuang Jia, Martin J. Hessner, John H. Griffin, Wolfram Ruf, Hartmut Weiler - Blood 2015 cited by 81

  16. 3K3A-activated protein C blocks amyloidogenic BACE1 pathway and improves functional outcome in mice

    Authors: Divna Lazić, Abhay P. Sagare, Angeliki M. Nikolakopoulou, John H. Griffin, Robert Vassar, Berislav V. Zloković - The Journal of Experimental Medicine 2019 cited by 67

  17. Activated Protein C Strengthens Cardiac Tolerance to Ischemic Insults in Aging

    Authors: Di Ren, Julia Fedorova, Kayla Davitt, Tran Ngoc Van Le, John H. Griffin, Patricia C. Liaw, Charles T. Esmon, Alireza R. Rezaie, Ji Li - Circulation Research 2021 cited by 26

  18. Biased agonism of protease-activated receptor 1 by activated protein C caused by noncanonical cleavage at Arg46

    Authors: Laurent O. Mosnier, Ranjeet Sinha, Laurent Burnier, Eveline A. M. Bouwens, John H. Griffin - Blood 2012 cited by 215

  19. Different DOACs Control Inflammation in Cardiac Ischemia-Reperfusion Differently

    Authors: Ihsan Gadi, Sameen Fatima, Ahmed Elwakiel, Sumra Nazir, Moh’d Mohanad Al‐Dabet, Rajiv Rana, Fabian Bock, Jayakumar Manoharan, Dheerendra Gupta, Ronald Biemann, Bernhard Nieswandt, Ruediger C. Braun‐Dullaeus, Christian Besler, Markus Scholz, Robert Geffers, John H. Griffin, Charles T. Esmon, Shrey Kohli, Berend Isermann, Khurrum Shahzad - Circulation Research 2020 cited by 40

  20. FVIIa (Factor VIIa) Induces Biased Cytoprotective Signaling in Mice Through the Cleavage of PAR (Protease-Activated Receptor)-1 at Canonical Arg41 (Arginine41) Site

    Authors: Vijay Kondreddy, Usha R. Pendurthi, Xiao Xu, John H. Griffin, L. Vijaya Mohan Rao - Arteriosclerosis Thrombosis and Vascular Biology 2020 cited by 29

  21. Protein synthesis by native chemical ligation: Expanded scope by using straightforward methodology

    Authors: Tilman M. Hackeng, John H. Griffin, Philip E. Dawson - National Academy of Sciences, Proceedings of the National Academy of Sciences 1999 cited by 671

  22. Protein C anticoagulant and cytoprotective pathways

    Authors: John H. Griffin, Berislav V. Zloković, Laurent O. Mosnier - International Journal of Hematology 2012 cited by 138

  23. 3K3A–activated protein C stimulates postischemic neuronal repair by human neural stem cells in mice

    Authors: Yaoming Wang, Zhen Zhao, Sanket Rege, Min Wang, Gabriel Si, Yi Zhou, Su Wang, John H. Griffin, Steven A. Goldman, Berislav V. Zloković - Nature Medicine 2016 cited by 111

  24. PAR1 biased signaling is required for activated protein C in vivo benefits in sepsis and stroke

    Authors: Ranjeet Sinha, Yaoming Wang, Zhen Zhao, Xiao Xu, Laurent Burnier, Naveen Gupta, José A. Fernández, Greg Martin, S.V. Kupriyanov, Laurent O. Mosnier, Berislav V. Zloković, John H. Griffin - Blood 2018 cited by 104