John Kuriyan
Active 1986–2025
- 166
- Papers
- 49,261
- Citations
- 111
- h-index
- 164
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology54.7%
- Medicine26.8%
- Immunology and Microbiology4.9%
- Materials Science2.7%
- Computer Science2.6%
- Neuroscience2.6%
- Other5.7%
Topics
- Protein Structure and Dynamics4.5%
- Protein Kinase Regulation and GTPase Signaling3.4%
- Enzyme Structure and Function3.3%
- Chronic Myeloid Leukemia Treatments2.5%
- RNA and protein synthesis mechanisms2.2%
- Computational Drug Discovery Methods2.1%
- Other82%
Coauthors
- Mike O’Donnell21
- Jay T. Groves15
- Arthur Weiss11
- Markus A. Seeliger10
- Neel H. Shah10
- Christine L. Gee9
- Dafna Bar‐Sagi9
- Bhushan Nagar8
- David Jeruzalmi8
- Deepti Karandur8
- Martin Karplus8
- Patricia Pellicena8
- Holger Sondermann7
- Matthew A. Young7
- Qi Wang7
- Sebastian Deindl7
- Theresa A. Kadlecek7
- Tiago Barros7
- Yasushi Kondo7
- Angus C. Nairn6
- David E. Shaw6
- David E. Wemmer6
- Howard Schulman6
- Ismail Moarefi6
All papers
- An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
Authors: Xuewu Zhang, Jodi Gureasko, Kui Shen, Philip A. Cole, John Kuriyan - Cell 2006 cited by 1,666
- Molecular dynamics and protein function
Authors: Martin Karplus, John Kuriyan - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 cited by 1,155
- A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS
Authors: William Y. C. Huang, Steven Alvarez, Yasushi Kondo, Young Kwang Lee, Jean K. Chung, Hiu Yue Monatrice Lam, Kabir H. Biswas, John Kuriyan, Jay T. Groves - Science 2019 cited by 384
- The Conformational Plasticity of Protein Kinases
Authors: Morgan Huse, John Kuriyan - Cell 2002 cited by 1,774
- Structural basis and regulation of the reductive stress response
Authors: Andrew G. Manford, Elijah L. Mena, Karen Y. Shih, Christine L. Gee, Rachael McMinimy, Brenda Martínez‐González, Rumi Sherriff, Brandon G. Lew, Madeline Zoltek, Fernando Rodríguez-Pérez, Makda Woldesenbet, John Kuriyan, Michael Rapé - Cell 2021 cited by 153
- Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction
Authors: K.R. Simonetta, Joshua P. Taygerly, Kathleen Boyle, Stephen E. Basham, Chris Padovani, Yan Lou, Thomas J. Cummins, Stephanie Yung, Szerenke Kiss Von Soly, Frank Kayser, John Kuriyan, Michael Rapé, Mario Cardozo, Mark A. Gallop, Neil Bence, Paul A. Barsanti, Anjanabha Saha - Nature Communications 2019 cited by 209
- Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase
Authors: Thomas H. Schindler, William G. Bornmann, Patricia Pellicena, W. Todd Miller, Bayard Clarkson, John Kuriyan - Science 2000 cited by 1,787
- Architecture and Membrane Interactions of the EGF Receptor
Authors: Anton Arkhipov, Yibing Shan, Rahul Das, Nicholas Endres, Michael P. Eastwood, David E. Wemmer, John Kuriyan, David E. Shaw - Cell 2013 cited by 528
- The structural basis of the activation of Ras by Sos
Authors: P. Ann Boriack‐Sjodin, S.M. Margarit, Dafna Bar‐Sagi, John Kuriyan - Nature 1998 cited by 805
- Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane Segment
Authors: Natalia Jura, Nicholas Endres, Kate Engel, Sebastian Deindl, Rahul Das, Meindert H. Lamers, David E. Wemmer, Xuewu Zhang, John Kuriyan - Cell 2009 cited by 624
- Structural Basis for the Autoinhibition of c-Abl Tyrosine Kinase
Authors: Bhushan Nagar, Oliver Hantschel, Matthew A. Young, Klaus Scheffzek, Darren R. Veach, William G. Bornmann, Bayard Clarkson, Giulio Superti‐Furga, John Kuriyan - Cell 2003 cited by 886
- Conformational Coupling across the Plasma Membrane in Activation of the EGF Receptor
Authors: Nicholas Endres, Rahul Das, Adam W. Smith, Anton Arkhipov, Erika Kovács, Yongjian Huang, Jeffrey G. Pelton, Yibing Shan, David E. Shaw, David E. Wemmer, Jay T. Groves, John Kuriyan - Cell 2013 cited by 510
- A Structural Perspective on the Regulation of the Epidermal Growth Factor Receptor
Authors: Erika Kovács, Julie A. Zorn, Yongjian Huang, Tiago Barros, John Kuriyan - Annual Review of Biochemistry 2015 cited by 375
- Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases
Authors: Yasushi Kondo, Jana Ognjenović, Saikat Banerjee, Deepti Karandur, Alan Merk, Kayla Kulhanek, Kathryn Wong, Jeroen P. Roose, Sriram Subramaniam, John Kuriyan - Science 2019 cited by 197
- Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia
Authors: Catherine C. Smith, Qi Wang, Chen-Shan Chin, Sara Salerno, Lauren E. Damon, Mark J. Levis, Alexander E. Perl, Kevin Travers, Susana Wang, Jeremy P. Hunt, Patrick P. Zarrinkar, Eric E. Schadt, Andrew Kasarskis, John Kuriyan, Neil P. Shah - Nature 2012 cited by 750
- CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks
Authors: Joshua C. Cofsky, Deepti Karandur, Carolyn J. Huang, Isaac P. Witte, John Kuriyan, Jennifer A. Doudna - eLife 2020 cited by 121
- Structure of the C-Terminal Region of p21WAF1/CIP1 Complexed with Human PCNA
Authors: Jacqueline M. Gulbis, Zvi Kelman, J Hurwitz, Mike O’Donnell, John Kuriyan - Cell 1996 cited by 813
- Molecular basis for multimerization in the activation of the epidermal growth factor receptor
Authors: Yongjian Huang, Shashank Bharill, Deepti Karandur, Sean M. Peterson, Morgan Marita, Xiaojun Shi, Megan J. Kaliszewski, Adam W. Smith, Ehud Y. Isacoff, John Kuriyan - eLife 2016 cited by 206
- A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor
Authors: Yongjian Huang, Jana Ognjenovic, Deepti Karandur, Kate Miller, Alan Merk, Sriram Subramaniam, John Kuriyan - eLife 2021 cited by 90
- Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
Authors: Neil P. Shah, John Nicoll, Bhushan Nagar, M. Gorre, Ronald Paquette, John Kuriyan, Charles L. Sawyers - Cancer Cell 2002 cited by 1,625
- Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT
Authors: Wan‐Lin Lo, Neel H. Shah, Nagib Ahsan, Veronika Horková, Ondřej Štěpánek, Arthur R. Salomon, John Kuriyan, Arthur Weiss - Nature Immunology 2018 cited by 180
- Structural Insights into the Regulation of Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII)
Authors: Moitrayee Bhattacharyya, Deepti Karandur, John Kuriyan - Cold Spring Harbor Perspectives in Biology 2019 cited by 104
- A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane
Authors: Chun‐Wei Lin, Laura M. Nocka, Brittany Stinger, Joseph B. DeGrandchamp, L. J. Nugent Lew, Steven Alvarez, Henry T. Phan, Yasushi Kondo, John Kuriyan, Jay T. Groves - National Academy of Sciences, Proceedings of the National Academy of Sciences 2022 cited by 85
- Crystal Structure of a Tyrosine Phosphorylated STAT-1 Dimer Bound to DNA
Authors: Xiaomin Chen, Uwe Vinkemeier, Yanxiang Zhao, David Jeruzalmi, James Darnell, John Kuriyan - Cell 1998 cited by 722
