Mike O’Donnell
Active 1975–2024
- Also published as
- Mike O'Donnell
- 129
- Papers
- 19,473
- Citations
- 89
- h-index
- 125
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology76%
- Medicine14.7%
- Environmental Science2.7%
- Immunology and Microbiology1.2%
- Agricultural and Biological Sciences1.1%
- Materials Science1%
- Other3.3%
Topics
- DNA Repair Mechanisms19.9%
- Bacterial Genetics and Biotechnology8.6%
- DNA and Nucleic Acid Chemistry6.9%
- Genomics and Chromatin Dynamics5.3%
- CRISPR and Genetic Engineering3.9%
- RNA and protein synthesis mechanisms3.5%
- Other51.9%
Coauthors
- Roxana E. Georgescu22
- John Kuriyan21
- Nina Y. Yao16
- Huilin Li15
- Myron F. Goodman13
- Olga Yurieva12
- Jennifer Turner11
- Lance D. Langston10
- Zvi Kelman10
- René Onrust8
- Manju Hingorani7
- Chiara Indiani6
- David Jeruzalmi6
- Megan J. Davey6
- P. Todd Stukenberg6
- Roger Woodgate6
- Aaron M. Johnson5
- Fengwei Zheng5
- Grant D. Schauer5
- Jeff Finkelstein5
- Peter McInerney5
- Zuanning Yuan5
- Brian A. Kelch4
- Dan Zhang4
All papers
- Structure of the C-Terminal Region of p21WAF1/CIP1 Complexed with Human PCNA
Authors: Jacqueline M. Gulbis, Zvi Kelman, J Hurwitz, Mike O’Donnell, John Kuriyan - Cell 1996 cited by 813
- Principles and Concepts of DNA Replication in Bacteria, Archaea, and Eukarya
Authors: Mike O’Donnell, Lance D. Langston, Bruce Stillman - Cold Spring Harbor Perspectives in Biology 2013 cited by 376
- DNA unwinding mechanism of a eukaryotic replicative CMG helicase
Authors: Zuanning Yuan, Roxana E. Georgescu, Lin Bai, Dan Zhang, Huilin Li, Mike O’Donnell - Nature Communications 2020 cited by 81
- Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA
Authors: Fengwei Zheng, Roxana E. Georgescu, Huilin Li, Mike O’Donnell - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 cited by 71
- Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks
Authors: Lance D. Langston, Ryan Mayle, Grant D. Schauer, Olga Yurieva, Daniel Zhang, Nina Y. Yao, Roxana E. Georgescu, Mike O’Donnell - eLife 2017 cited by 99
- Cryo-EM structures reveal that RFC recognizes both the 3′- and 5′-DNA ends to load PCNA onto gaps for DNA repair
Authors: Fengwei Zheng, Roxana E. Georgescu, Nina Y. Yao, Huilin Li, Mike O’Donnell - eLife 2022 cited by 41
- Structural analysis of a eukaryotic sliding DNA clamp–clamp loader complex
Authors: Gregory D. Bowman, Mike O’Donnell, John Kuriyan - Nature 2004 cited by 460
- Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome
Authors: Zuanning Yuan, Roxana E. Georgescu, Grant D. Schauer, Mike O’Donnell, Huilin Li - Nature Communications 2020 cited by 85
- Three-dimensional structure of the β subunit of E. coli DNA polymerase III holoenzyme: A sliding DNA clamp
Authors: Xiang‐Peng Kong, René Onrust, Mike O’Donnell, John Kuriyan - Cell 1992 cited by 760
- Saccharomyces cerevisiae MutLα Is a Mismatch Repair Endonuclease
Authors: Farid A. Kadyrov, Shannon F. Holmes, Mercedes E. Arana, O.A. Lukianova, Mike O’Donnell, Thomas A. Kunkel, Paul Modrich - Journal of Biological Chemistry 2007 cited by 249
- Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork
Authors: Roxana E. Georgescu, Lance D. Langston, Nina Y. Yao, Olga Yurieva, Dan Zhang, Jeff Finkelstein, Tani Agarwal, Mike O’Donnell - Nature Structural & Molecular Biology 2014 cited by 198
- Nuclease dead Cas9 is a programmable roadblock for DNA replication
Authors: Kelsey S. Whinn, Gurleen Kaur, Jacob S. Lewis, Grant D. Schauer, S.H. Mueller, Slobodan Jergic, Hamish Maynard, Zhong Yan Gan, Matharishwan Naganbabu, Marcel P. Bruchez, Mike O’Donnell, Nicholas E. Dixon, Antoine M. van Oijen, Harshad Ghodke - Scientific Reports 2019 cited by 63
- DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp
Authors: Fengwei Zheng, Roxana E. Georgescu, Nina Y. Yao, Mike O’Donnell, Huilin Li - Nature Structural & Molecular Biology 2022 cited by 34
- Structure of a Sliding Clamp on DNA
Authors: Roxana E. Georgescu, Seung-Sup Kim, Olga Yurieva, John Kuriyan, Xiang‐Peng Kong, Mike O’Donnell - Cell 2008 cited by 247
- Clamp loading, unloading and intrinsic stability of the PCNA, β and gp45 sliding clamps of human, E. coli and T4 replicases
Authors: Nina Y. Yao, Jennifer Turner, Zvi Kelman, P. Todd Stukenberg, Frank B. Dean, David Shechter, Zhen‐Qiang Pan, J Hurwitz, Mike O’Donnell - Genes to Cells 1996 cited by 224
- Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation
Authors: Roxana E. Georgescu, Grant D. Schauer, Nina Y. Yao, Lance D. Langston, Olga Yurieva, Dan Zhang, Jeff Finkelstein, Mike O’Donnell - eLife 2015 cited by 140
- The RFC Clamp Loader: Structure and Function
Authors: Nina Y. Yao, Mike O’Donnell - Sub-cellular biochemistry/Subcellular biochemistry 2012 cited by 92
- Smc5/6’s multifaceted DNA binding capacities stabilize branched DNA structures
Authors: Jeremy Chang, Shibai Li, Emily C. Beckwitt, Thane Than, Cory Haluska, Joshua Chandanani, Mike O’Donnell, Xiaolan Zhao, Shixin Liu - Nature Communications 2022 cited by 25
- CELLULAR DNA REPLICASES: Components and Dynamics at the Replication Fork
Authors: Aaron M. Johnson, Mike O’Donnell - Annual Review of Biochemistry 2005 cited by 562
- Mechanism of the sliding beta-clamp of DNA polymerase III holoenzyme
Authors: P. Todd Stukenberg, P.S. Studwell-Vaughan, Mike O’Donnell - Journal of Biological Chemistry 1991 cited by 429
- Crystal Structure of the Processivity Clamp Loader Gamma (γ) Complex of E. coli DNA Polymerase III
Authors: David Jeruzalmi, Mike O’Donnell, John Kuriyan - Cell 2001 cited by 320
- Multiple competition reactions for RPA order the assembly of the DNA polymerase δ holoenzyme
Authors: A. A. Yuzhakov, Zvi Kelman, Jerard Hurwitz, Mike O’Donnell - The EMBO Journal 1999 cited by 215
- The replisome uses mRNA as a primer after colliding with RNA polymerase
Authors: Richard T. Pomerantz, Mike O’Donnell - Nature 2008 cited by 196
- How a DNA Polymerase Clamp Loader Opens a Sliding Clamp
Authors: Brian A. Kelch, Débora L. Makino, Mike O’Donnell, John Kuriyan - Science 2011 cited by 181
