Paul Modrich
Active 1970–2020
- 105
- Papers
- 26,725
- Citations
- 93
- h-index
- 105
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology61.2%
- Medicine31.3%
- Environmental Science1.9%
- Agricultural and Biological Sciences1.5%
- Neuroscience1.4%
- Immunology and Microbiology1.3%
- Other1.4%
Topics
- DNA Repair Mechanisms14.7%
- Genetic factors in colorectal cancer8.9%
- DNA and Nucleic Acid Chemistry4.1%
- RNA and protein synthesis mechanisms3.8%
- CRISPR and Genetic Engineering3.7%
- Cancer Genomics and Diagnostics3.7%
- Other61.1%
Coauthors
- Jochen Genschel9
- Farid A. Kadyrov7
- James T. Drummond7
- Guo‐Min Li6
- Ravi R. Iyer6
- S S Su6
- Suzanne Clark6
- Karin G. Au5
- Matthew J. Longley5
- Robert S. Lahue5
- Vickers Burdett5
- A-Lien Lu4
- I Lehman4
- Katherine M. Welsh4
- Leonid Dzantiev4
- Michelle Grilley4
- Nicoleta Constantin4
- William E. Jack4
- Anna Pluciennik3
- Aziz Sancar3
- Brian Terry3
- Celia Baitinger3
- Dwayne J. Allen3
- Francis Ali‐Osman3
All papers
- BLM–DNA2–RPA–MRN and EXO1–BLM–RPA–MRN constitute two DNA end resection machineries for human DNA break repair
Authors: Amitabh V. Nimonkar, Jochen Genschel, Eri Kinoshita, Piotr Polaczek, Judith L. Campbell, Claire Wyman, Paul Modrich, Stephen C. Kowalczykowski - Genes & Development 2011 cited by 736
- Endonucleolytic Function of MutLα in Human Mismatch Repair
Authors: Farid A. Kadyrov, Leonid Dzantiev, Nicoleta Constantin, Paul Modrich - Cell 2006 cited by 639
- DNA Mismatch Repair: Functions and Mechanisms
Authors: Ravi R. Iyer, Anna Pluciennik, Vickers Burdett, Paul Modrich - Chemical Reviews 2005 cited by 905
- Human MutLγ, the MLH1–MLH3 heterodimer, is an endonuclease that promotes DNA expansion
Authors: Lyudmila Y. Kadyrova, Vaibhavi Gujar, Vickers Burdett, Paul Modrich, Farid A. Kadyrov - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 cited by 88
- Mechanisms in Eukaryotic Mismatch Repair
Authors: Paul Modrich - Journal of Biological Chemistry 2006 cited by 452
- PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
Authors: Anna Pluciennik, Leonid Dzantiev, Ravi R. Iyer, Nicoleta Constantin, Farid A. Kadyrov, Paul Modrich - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 269
- MISMATCH REPAIR IN REPLICATION FIDELITY, GENETIC RECOMBINATION, AND CANCER BIOLOGY
Authors: Paul Modrich, Robert S. Lahue - Annual Review of Biochemistry 1996 cited by 1,498
- Isolation of MutSβ from Human Cells and Comparison of the Mismatch Repair Specificities of MutSβ and MutSα
Authors: Jochen Genschel, Susan J. Littman, James T. Drummond, Paul Modrich - Journal of Biological Chemistry 1998 cited by 416
- Saccharomyces cerevisiae MutLα Is a Mismatch Repair Endonuclease
Authors: Farid A. Kadyrov, Shannon F. Holmes, Mercedes E. Arana, O.A. Lukianova, Mike O’Donnell, Thomas A. Kunkel, Paul Modrich - Journal of Biological Chemistry 2007 cited by 249
- Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture)
Authors: Paul Modrich - Angewandte Chemie International Edition 2016 cited by 102
- Structure of the Human MutSα DNA Lesion Recognition Complex
Authors: J.J. Warren, T.J. Pohlhaus, Anita Changela, Ravi R. Iyer, Paul Modrich, L.S. Beese - Molecular Cell 2007 cited by 371
- Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
Authors: Anna Pluciennik, Vickers Burdett, Celia Baitinger, Ravi R. Iyer, Kevin Shi, Paul Modrich - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 84
- Hypermutability and mismatch repair deficiency in RER+ tumor cells
Authors: Ramon Parsons, Guo‐Min Li, Matthew J. Longley, Woei-horng Fang, Nickolas Papadopoulos, Jin Jen, Albert de la Chapelle, Kenneth W. Kinzler, B Vogelstein, Paul Modrich - Cell 1993 cited by 1,061
- Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
Authors: Martina Veigl, Lakshmi Kasturi, Joseph Olechnowicz, AiHong Ma, James Lutterbaugh, Sumudra Periyasamy, Guo‐Min Li, James T. Drummond, Paul Modrich, W. David Sedwick, Sanford D. Markowitz - National Academy of Sciences, Proceedings of the National Academy of Sciences 1998 cited by 635
- DNA Mismatch Correction in a Defined System
Authors: Robert S. Lahue, Karin G. Au, Paul Modrich - Science 1989 cited by 559
- Mispair specificity of methyl-directed DNA mismatch correction in vitro.
Authors: S S Su, Robert S. Lahue, Karin G. Au, Paul Modrich - Journal of Biological Chemistry 1988 cited by 339
- Targeting Wide-Range Oncogenic Transformation via PU24FCl, a Specific Inhibitor of Tumor Hsp90
Authors: Maria Vilenchik, David B. Solit, Andrea Basso, Henri Huezo, Brian S. Lucas, Huazhong He, Neal Rosen, Claudia P. Spampinato, Paul Modrich, Gabriela Chiosis - Chemistry & Biology 2004 cited by 170
- A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair
Authors: Farid A. Kadyrov, Jochen Genschel, Yanan Fang, Elisabeth Penland, Winfried Edelmann, Paul Modrich - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 cited by 140
- HIF-1α Induces Genetic Instability by Transcriptionally Downregulating MutSα Expression
Authors: Minori Koshiji, Kenneth K.W. To, Stefanie Hammer, Kensuke Kumamoto, Adrian L. Harris, Paul Modrich, Eric Huang - Molecular Cell 2005 cited by 346
- Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
Authors: Jillian Orans, Elizabeth McSweeney, Ravi Iyer, Michael A. Hast, Homme W. Hellinga, Paul Modrich, L.S. Beese - Cell 2011 cited by 165
- MECHANISMS AND BIOLOGICAL EFFECTS OF MISMATCH REPAIR
Authors: Paul Modrich - Annual Review of Genetics 1991 cited by 883
- DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma.
Authors: H. S. Friedman, R E McLendon, Tracy Kerby, Margaret Dugan, Sandra H. Bigner, A J Henry, David M. Ashley, Jacob Krischer, Simon C. Lovell, Karima Rasheed, F Marchev, A J Seman, Ilkcan Cokgor, Jeremy N. Rich, Elizabeth A. Stewart, O. Michael Colvin, J M Provenzale, Bigner Dd, M M Haglund, A H Friedman, Paul Modrich - Journal of Clinical Oncology 1998 cited by 422
- Initiation of methyl-directed mismatch repair.
Authors: Karin G. Au, Katherine M. Welsh, Paul Modrich - Journal of Biological Chemistry 1992 cited by 313
- Mechanism of 5′-Directed Excision in Human Mismatch Repair
Authors: Jochen Genschel, Paul Modrich - Molecular Cell 2003 cited by 252
