John Kyriakis
Active 1990–2012
- 56
- Papers
- 24,034
- Citations
- 56
- h-index
- 56
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology60.4%
- Medicine25%
- Immunology and Microbiology4.9%
- Neuroscience4.1%
- Agricultural and Biological Sciences1.7%
- Environmental Science0.8%
- Other3.1%
Topics
- Melanoma and MAPK Pathways6.7%
- Protein Kinase Regulation and GTPase Signaling6.2%
- Cell death mechanisms and regulation3.2%
- NF-κB Signaling Pathways3.1%
- Cytokine Signaling Pathways and Interactions2.3%
- Heat shock proteins research1.6%
- Other76.9%
Coauthors
- Joseph Avruch27
- Thomas Force12
- James R. Woodgett11
- Joseph V. Bonventre8
- Leonard I. Zon8
- Celia M. Pombo5
- Ulf R. Rapp5
- Shigeo Ohno4
- Da-Zhong Xu3
- Deborah Chadee3
- Elizabeth A. Rubie3
- Tianang Dai3
- Xianfeng Zhang3
- Ajay Rana2
- Anthony Makkinje2
- David L. Brautigan2
- Eleni Nikolakaki2
- John H. Kehrl2
- Joseph T. Bruder2
- Keisuke Kuida2
- Mark Namchuk2
- Papia T. Banerjee2
- Takashi Yuasa2
- Zhijun Luo2
All papers
- Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update
Authors: John Kyriakis, Joseph Avruch - Physiological Reviews 2012 cited by 1,461
- Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
Authors: John Kyriakis, Joseph Avruch - Physiological Reviews 2001 cited by 3,374
- The stress-activated protein kinase subfamily of c-Jun kinases
Authors: John Kyriakis, Papia T. Banerjee, Eleni Nikolakaki, Tianang Dai, Elizabeth A. Rubie, Mir F. Ahmad, Joseph Avruch, James R. Woodgett - Nature 1994 cited by 2,618
- Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
Authors: Marcel Verheij, Ron Bose, Xin Lin, Bei Yao, W. David Jarvis, Steven Grant, Michael J. Birrer, Éva Szabó, Leonard I. Zon, John Kyriakis, Adriana Haimovitz‐Friedman, Zvi Fuks, Richard Kolesnick - Nature 1996 cited by 1,797
- Activation of Apoptosis Signal-Regulating Kinase 1 (ASK1) by Tumor Necrosis Factor Receptor-Associated Factor 2 Requires Prior Dissociation of the ASK1 Inhibitor Thioredoxin
Authors: Hong Liu, Hideki Nishitoh, Hidenori Ichijo, John Kyriakis - Molecular and Cellular Biology 2000 cited by 553
- Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
Authors: Xianfeng Zhang, Jeffrey Settleman, John Kyriakis, Erika Takeuchi-Suzuki, Stephen J. Elledge, Mark S. Marshall, Joseph T. Bruder, Ulf R. Rapp, Joseph Avruch - Nature 1993 cited by 883
- Activation of the AP-1 transcription factor by inflammatory cytokines of the TNF family.
Authors: John Kyriakis - 1999 cited by 125
- Phosphorylation of c-jun mediated by MAP kinases
Authors: Bernd Pulverer, John Kyriakis, Joseph Avruch, Eleni Nikolakaki, James R. Woodgett - Nature 1991 cited by 1,496
- Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation.
Authors: Jakob Troppmair, Joseph T. Bruder, Hugo Roberto Muñoz, Patricia A. Lloyd, John Kyriakis, Probal Banerjee, Joseph Avruch, Ulf R. Rapp - Journal of Biological Chemistry 1994 cited by 240
- Raf-1 activates MAP kinase-kinase
Authors: John Kyriakis, Harald App, Xianfeng Zhang, Papia T. Banerjee, David L. Brautigan, Ulf R. Rapp, Joseph Avruch - Nature 1992 cited by 1,306
- Sounding the Alarm: Protein Kinase Cascades Activated by Stress and Inflammation
Authors: John Kyriakis, Joseph Avruch - Journal of Biological Chemistry 1996 cited by 1,093
- Raf meets Ras: completing the framework of a signal transduction pathway
Authors: Joseph Avruch, Xianfeng Zhang, John Kyriakis - Trends in Biochemical Sciences 1994 cited by 591
- pp54 microtubule-associated protein 2 kinase. A novel serine/threonine protein kinase regulated by phosphorylation and stimulated by poly-L-lysine.
Authors: John Kyriakis, Joseph Avruch - Journal of Biological Chemistry 1990 cited by 259
- MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation
Authors: Deborah Chadee, John Kyriakis - Nature Cell Biology 2004 cited by 166
- Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein
Authors: Deborah Chadee, Da-Zhong Xu, Gene Hung, Ali Andalibi, David Lim, Zhijun Luo, David H. Gutmann, John Kyriakis - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 cited by 96
- Direct Activation of Mitogen-Activated Protein Kinase Kinase Kinase MEKK1 by the Ste20p Homologue GCK and the Adapter Protein TRAF2
Authors: Deborah Chadee, Takashi Yuasa, John Kyriakis - Molecular and Cellular Biology 2002 cited by 86
- The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat
Authors: Brent W. Zanke, Kimberly Boudreau, Elizabeth A. Rubie, Elaine Winnett, Lee Anne Tibbles, Leonard I. Zon, John Kyriakis, Fei‐Fei Liu, James R. Woodgett - Current Biology 1996 cited by 451
- The Mixed Lineage Kinase SPRK Phosphorylates and Activates the Stress-activated Protein Kinase Activator, SEK-1
Authors: Ajay Rana, Kathleen A. Gallo, Paul J. Godowski, Shu-ichi Hirai, Shigeo Ohno, Leonard I. Zon, John Kyriakis, Joseph Avruch - Journal of Biological Chemistry 1996 cited by 222
- c-Jun N-Terminal Kinases Mediate Reactivation of Akt and Cardiomyocyte Survival After Hypoxic Injury In Vitro and In Vivo
Authors: Zhili Shao, Kausik Bhattacharya, Eileen Hsich, Larry Park, Brian Walters, Ursula A. Germann, Yow‐Ming Wang, John Kyriakis, Ramon Mohanlal, Keisuke Kuida, Mark Namchuk, Francesco G. Salituro, Yung‐Mae Yao, Weimin Hou, Xin Chen, Mark Aronovitz, Philip N. Tsichlis, Susmita Bhattacharya, Thomas Force, Heiko Kilter - Circulation Research 2005 cited by 124
- Gene 33 Is an Endogenous Inhibitor of Epidermal Growth Factor (EGF) Receptor Signaling and Mediates Dexamethasone-induced Suppression of EGF Function
Authors: Da-Zhong Xu, Anthony Makkinje, John Kyriakis - Journal of Biological Chemistry 2004 cited by 117
- Mitogen regulation of c-Raf-1 protein kinase activity toward mitogen-activated protein kinase-kinase
Authors: John Kyriakis, Thomas Force, Ulf R. Rapp, Joseph V. Bonventre, Joseph Avruch - Journal of Biological Chemistry 1993 cited by 112
- Protein kinase cascades activated by stress and inflammatory cytokines
Authors: John Kyriakis, Joseph Avruch - BioEssays 1996 cited by 715
- Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1
Authors: Mlnhong Yan, Tianang Dai, Joseph C. Deak, John Kyriakis, Leonard I. Zon, James R. Woodgett, Dennis J. Templeton - Nature 1994 cited by 708
- Tumor Necrosis Factor Signaling to Stress-activated Protein Kinase (SAPK)/Jun NH2-terminal Kinase (JNK) and p38
Authors: Takashi Yuasa, Shigeo Ohno, John H. Kehrl, John Kyriakis - Journal of Biological Chemistry 1998 cited by 269
