Joseph Avruch
Active 1971–2021
- 130
- Papers
- 44,403
- Citations
- 104
- h-index
- 130
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology66.3%
- Medicine22.4%
- Immunology and Microbiology3.8%
- Neuroscience3.1%
- Agricultural and Biological Sciences1.5%
- Nursing0.5%
- Other2.4%
Topics
- Protein Kinase Regulation and GTPase Signaling5.5%
- PI3K/AKT/mTOR signaling in cancer4.8%
- Melanoma and MAPK Pathways4.1%
- Hippo pathway signaling and YAP/TAZ3.6%
- Ubiquitin and proteasome pathways1.9%
- Metabolism, Diabetes, and Cancer1.8%
- Other78.3%
Coauthors
- John Kyriakis27
- Xianfeng Zhang12
- Dawang Zhou11
- Kazuyoshi Yonezawa10
- Kenta Hara10
- James R. Woodgett9
- Ning Dai9
- Sara Ortiz-Vega8
- Christopher Belham7
- Daniel J. Price7
- Laura Regué7
- Samuel Long7
- Zhijun Luo7
- Maria Praskova6
- Mark T. Kozlowski6
- Nabeel Bardeesy6
- Thomas Force6
- Ulf R. Rapp6
- Guri Tzivion5
- Jeffrey Grove5
- Joan Roig5
- Liliana Minichiello5
- Qing-Ping Weng5
- Raphael A. Nemenoff5
All papers
- Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update
Authors: John Kyriakis, Joseph Avruch - Physiological Reviews 2012 cited by 1,461
- Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation
Authors: Karin Schlegelmilch, Morvarid Mohseni, Oktay Kirak, Jan Pruszak, J. Renato Rodriguez, Dawang Zhou, Bridget Kreger, Valera Vasioukhin, Joseph Avruch, Thijn R. Brummelkamp, Fernando D. Camargo - Cell 2011 cited by 1,067
- Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
Authors: John Kyriakis, Joseph Avruch - Physiological Reviews 2001 cited by 3,374
- Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action
Authors: Kenta Hara, Yoshiko Maruki, Samuel Long, K. Yoshino, Noriko Oshiro, Hidayat Sujuti, Chiharu Tokunaga, Joseph Avruch, Kazuyoshi Yonezawa - Cell 2002 cited by 1,800
- Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene
Authors: Dawang Zhou, Claudius Conrad, Fan Xia, Ji-Sun Park, Bernhard Payer, Yi Yin, Gregory Y. Lauwers, Wolfgang E. Thasler, Jeannie T. Lee, Joseph Avruch, Nabeel Bardeesy - Cancer Cell 2009 cited by 936
- Amino Acid Sufficiency and mTOR Regulate p70 S6 Kinase and eIF-4E BP1 through a Common Effector Mechanism
Authors: Kenta Hara, Kazuyoshi Yonezawa, Qing-Ping Weng, Mark T. Kozlowski, Christopher Belham, Joseph Avruch - Journal of Biological Chemistry 1998 cited by 1,363
- Rheb Binds and Regulates the mTOR Kinase
Authors: Samuel Long, Yenshou Lin, Sara Ortiz-Vega, Kazuyoshi Yonezawa, Joseph Avruch - Current Biology 2005 cited by 990
- MOBKL1A/MOBKL1B Phosphorylation by MST1 and MST2 Inhibits Cell Proliferation
Authors: Maria Praskova, Fan Xia, Joseph Avruch - Current Biology 2008 cited by 423
- Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity
Authors: Jing Geng, Xiufeng Sun, Ping Wang, Shihao Zhang, Xiaozhen Wang, Hongtan Wu, Lixin Hong, Changchuan Xie, Xun Li, Hao Zhao, Qingxu Liu, Mingting Jiang, Qinghua Chen, Jinjia Zhang, Terytty Yang Li, Siyang Song, Hongrui Wang, Rongbin Zhou, Randy L. Johnson, Kun‐Yi Chien, Sheng‐Cai Lin, Jiahuai Han, Joseph Avruch, Lanfen Chen, Dawang Zhou - Nature Immunology 2015 cited by 265
- Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance
Authors: Dawang Zhou, Yongyou Zhang, Hongtan Wu, Evan Barry, Yi Yin, Earl Lawrence, Dawn Dawson, Joseph Willis, Sanford D. Markowitz, Fernando D. Camargo, Joseph Avruch - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 451
- The Mammalian Target of Rapamycin (mTOR) Partner, Raptor, Binds the mTOR Substrates p70 S6 Kinase and 4E-BP1 through Their TOR Signaling (TOS) Motif
Authors: H Nojima, Chiharu Tokunaga, Satoshi Eguchi, Noriko Oshiro, Hidayat Sujuti, Kenichi Yoshino, Kenta Hara, Noriaki Tanaka, Joseph Avruch, Kazuyoshi Yonezawa - Journal of Biological Chemistry 2003 cited by 681
- YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression
Authors: Julien Fitamant, Filippos Kottakis, Samira Benhamouche, Helen S. Tian, Nicolas Chuvin, Christine A. Parachoniak, Julia M. Nagle, Rushika M. Perera, Marjorie Lapouge, Vikram Deshpande, Andrew X. Zhu, Albert Lai, Bosun Min, Yujin Hoshida, Joseph Avruch, Daniela Sia, Genís Campreciós, Andrea I. McClatchey, Josep M. Llovet, David Morrissey, Lakshmi Raj, Nabeel Bardeesy - Cell Reports 2015 cited by 251
- mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry
Authors: Ning Dai, Joseph Rapley, Matthew Angel, Mehmet Fatih Yanik, Michael D. Blower, Joseph Avruch - Genes & Development 2011 cited by 212
- The stress-activated protein kinase subfamily of c-Jun kinases
Authors: John Kyriakis, Papia T. Banerjee, Eleni Nikolakaki, Tianang Dai, Elizabeth A. Rubie, Mir F. Ahmad, Joseph Avruch, James R. Woodgett - Nature 1994 cited by 2,618
- Nek9 is a Plk1‐activated kinase that controls early centrosome separation through Nek6/7 and Eg5
Authors: M. Teresa Bertran, Sara Sdelci, Laura Regué, Joseph Avruch, Carmé Caelles, Joan Roig - The EMBO Journal 2011 cited by 191
- Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk
Authors: William W. Greenwald, Joshua Chiou, Jian Yan, Yunjiang Qiu, Ning Dai, Allen Wang, Naoki Nariai, Anthony Aylward, Jee Yun Han, Nikita Kadakia, Laura Regué, Mei-Lin Okino, Frauke Drees, Dana Krämer, Nicholas K. Vinckier, Liliana Minichiello, David U. Gorkin, Joseph Avruch, Kelly A. Frazer, Maike Sander, Bing Ren, Kyle J. Gaulton - Nature Communications 2019 cited by 122
- Regulation of eIF-4E BP1 Phosphorylation by mTOR
Authors: Kenta Hara, Kazuyoshi Yonezawa, Mark T. Kozlowski, Tadanori Sugimoto, Khurshid Iqbal Andrabi, Qing-Ping Weng, Masato Kasuga, Ikuo Nishimoto, Joseph Avruch - Journal of Biological Chemistry 1997 cited by 516
- IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins
Authors: Ning Dai, Liping Zhao, Diedra M. Wrighting, Dana Krämer, Amit R. Majithia, Yanqun Wang, Valentin Cracan, Diego Borges-Rivera, Vamsi K. Mootha, Matthias Nahrendorf, David R. Thorburn, Liliana Minichiello, David Altshuler, Joseph Avruch - Cell Metabolism 2015 cited by 198
- A MicroRNA Linking Human Positive Selection and Metabolic Disorders
Authors: Lifeng Wang, Nasa Sinnott-Armstrong, Alexandre Wagschal, Abigail R. Wark, João Paulo Camporez, Rachel J. Perry, Fei Ji, Yoojin Sohn, Justin D. Oh, Su Wu, Jessica Chery, Bahareh Nemati Moud, Alham Saadat, Simon N. Dankel, Gunnar Mellgren, Divya Sri Priyanka Tallapragada, Sophie Strobel, Mi‐Jeong Lee, Ryan Tewhey, Pardis C. Sabeti, Anne Schaefer, Andreas Petri, Sakari Kauppinen, Raymond T. Chung, Alexander A. Soukas, Joseph Avruch, Susan K. Fried, Hans Hauner, Ruslan I. Sadreyev, Gerald I. Shulman, Melina Claussnitzer, Anders M. Näär - Cell 2020 cited by 77
- Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
Authors: Xianfeng Zhang, Jeffrey Settleman, John Kyriakis, Erika Takeuchi-Suzuki, Stephen J. Elledge, Mark S. Marshall, Joseph T. Bruder, Ulf R. Rapp, Joseph Avruch - Nature 1993 cited by 883
- MAP kinase pathways: The first twenty years
Authors: Joseph Avruch - Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2006 cited by 282
- A Mitotic Cascade of NIMA Family Kinases
Authors: Christopher Belham, Joan Roig, Jennifer Caldwell, Yumi Aoyama, Bruce E. Kemp, Michael J. Comb, Joseph Avruch - Journal of Biological Chemistry 2003 cited by 189
- A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity
Authors: Guri Tzivion, Zhijun Luo, Joseph Avruch - Nature 1998 cited by 481
- Ras Activation of the Raf Kinase: Tyrosine Kinase Recruitment of the MAP Kinase Cascade
Authors: Joseph Avruch - Recent Progress in Hormone Research 2001 cited by 392
