John M. Coffin
Active 1971–2024
- 129
- Papers
- 26,592
- Citations
- 97
- h-index
- 127
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Immunology and Microbiology47.6%
- Medicine20.9%
- Biochemistry, Genetics and Molecular Biology18.4%
- Agricultural and Biological Sciences9.8%
- Environmental Science0.9%
- Neuroscience0.8%
- Other1.6%
Topics
- HIV Research and Treatment18%
- HIV/AIDS drug development and treatment9.6%
- HIV/AIDS Research and Interventions6.2%
- Immune Cell Function and Interaction5.1%
- CRISPR and Genetic Engineering3.8%
- Chromosomal and Genetic Variations3.1%
- Other54.2%
Coauthors
- John W. Mellors45
- Mary F. Kearney42
- Frank Maldarelli29
- Sarah Palmer26
- Wei Shao25
- Ann Wiegand23
- Stephen H. Hughes18
- Elias K. Halvas17
- Jonathan P. Stoye14
- Jonathan Spindler14
- Xiaolin Wu14
- Michael J. Bale12
- Michele D. Sobolewski10
- Wayne N. Frankel10
- Brandon F. Keele8
- Brian T. Luke8
- Catherine Rehm8
- Joseph J. Eron8
- Ronald J. Bosch8
- Shuang Guo8
- David M. Margolis7
- Valerie F. Boltz7
- Daria Wells6
- Francesco R. Simonetti6
All papers
- Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
Authors: Frank Maldarelli, Xiaolin Wu, Li Su, Francesco R. Simonetti, Wei Shao, S. Hill, Jonathan Spindler, Andrea L. Ferris, John W. Mellors, Mary F. Kearney, John M. Coffin, Stephen H. Hughes - Science 2014 cited by 901
- Clonally expanded CD4 + T cells can produce infectious HIV-1 in vivo
Authors: Francesco R. Simonetti, Michele D. Sobolewski, Elizabeth Fyne, Wei Shao, Jonathan Spindler, Junko Hattori, Elizabeth M. Anderson, Sarah A. Watters, Shawn Hill, Xiaolin Wu, David W. Wells, Li Su, Brian T. Luke, Elias K. Halvas, Guillaume Besson, Kerri J. Penrose, Zhiming Yang, Richard Kwan, Carter Van Waes, Thomas S. Uldrick, Deborah E. Citrin, Joseph A. Kovacs, Michael A. Polis, Catherine Rehm, Robert J. Gorelick, Michael Piatak, Brandon F. Keele, Mary F. Kearney, John M. Coffin, Stephen H. Hughes, John W. Mellors, Frank Maldarelli - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 382
- Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir
Authors: John Bui, Michele D. Sobolewski, Brandon F. Keele, Jonathan Spindler, Andrew Musick, Ann Wiegand, Brian T. Luke, Wei Shao, Stephen H. Hughes, John M. Coffin, Mary F. Kearney, John W. Mellors - PLoS Pathogens 2017 cited by 257
- Flexible Use of Nuclear Import Pathways by HIV-1
Authors: Kyeongeun Lee, Zandrea Ambrose, Thomas D. Martin, Ilker Öztop, Alok Mulky, John G. Julias, Nick Vandegraaff, Joerg G. Baumann, Rui Wang, Wendy Yuen, Taichiro Takemura, Kenneth Shelton, Ichiro Taniuchi, Yuan Li, Joseph Sodroski, Dan R. Littman, John M. Coffin, Stephen H. Hughes, Derya Unutmaz, Alan Engelman, Vineet N. KewalRamani - Cell Host & Microbe 2010 cited by 470
- Identification, characterization, and comparative genomic distribution of the HERV-K (HML-2) group of human endogenous retroviruses
Authors: Ravi P. Subramanian, Julia H Wildschutte, Crystal Russo, John M. Coffin - Retrovirology 2011 cited by 460
- Discovery of unfixed endogenous retrovirus insertions in diverse human populations
Authors: Julia H Wildschutte, Zachary H. Williams, Meagan Montesion, Ravi P. Subramanian, Jeffrey M. Kidd, John M. Coffin - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 289
- HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus
Authors: Elias K. Halvas, Kevin W. Joseph, Leah D. Brandt, Shuang Guo, Michele D. Sobolewski, Jana L. Jacobs, Camille Tumiotto, John Bui, Joshua C. Cyktor, Brandon F. Keele, Gene D. Morse, Michael J. Bale, Wei Shao, Mary F. Kearney, John M. Coffin, Jason W. Rausch, Xiaolin Wu, Stephen H. Hughes, John W. Mellors - Journal of Clinical Investigation 2020 cited by 149
- Effects of Retroviruses on Host Genome Function
Authors: Patric Jern, John M. Coffin - Annual Review of Genetics 2008 cited by 508
- Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy
Authors: Sarah Palmer, Frank Maldarelli, Ann Wiegand, Barry Bernstein, George J. Hanna, Scott C. Brun, Dale J. Kempf, John W. Mellors, John M. Coffin, Martin King - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 646
- Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART
Authors: Ann Wiegand, Jonathan Spindler, Feiyu Hong, Wei Shao, Joshua C. Cyktor, Anthony R. Cillo, Elias K. Halvas, John M. Coffin, John W. Mellors, Mary F. Kearney - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 cited by 179
- Widespread expression of the ancient HERV-K (HML-2) provirus group in normal human tissues
Authors: Aidan Burn, Farrah Roy, Michael Freeman, John M. Coffin - PLoS Biology 2022 cited by 65
- Clinical Trial of the Anti-PD-L1 Antibody BMS-936559 in HIV-1 Infected Participants on Suppressive Antiretroviral Therapy
Authors: Cynthia L. Gay, Ronald J. Bosch, Justin Ritz, Jason Hataye, Evgenia Aga, Randall L. Tressler, Stephen W. Mason, Carey Hwang, Dennis M. Grasela, Neelanjana Ray, Josh C. Cyktor, John M. Coffin, Edward P. Acosta, Richard A. Koup, John W. Mellors, Joseph J. Eron - The Journal of Infectious Diseases 2017 cited by 221
- ICTV Virus Taxonomy Profile: Retroviridae 2021
Authors: John M. Coffin, Jonas Blomberg, Hung Fan, Robert J. Gifford, Théodora Hatziioannou, Dirk Lindemann, Jens Mayer, Jonathan P. Stoye, Michael Tristem, Welkin E. Johnson - Journal of General Virology 2021 cited by 67
- HIV Population Dynamics in Vivo: Implications for Genetic Variation, Pathogenesis, and Therapy
Authors: John M. Coffin - Science 1995 cited by 1,993
- HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy
Authors: William R. McManus, Michael J. Bale, Jonathan Spindler, Ann Wiegand, Andrew Musick, Sean C. Patro, Michele D. Sobolewski, Victoria K. Musick, Elizabeth M. Anderson, Joshua C. Cyktor, Elias K. Halvas, Wei Shao, Daria Wells, Xiaolin Wu, Brandon F. Keele, Jeffrey M. Milush, Rebecca Hoh, John W. Mellors, Stephen H. Hughes, Steven G. Deeks, John M. Coffin, Mary F. Kearney - Journal of Clinical Investigation 2019 cited by 122
- New Real-Time Reverse Transcriptase-Initiated PCR Assay with Single-Copy Sensitivity for Human Immunodeficiency Virus Type 1 RNA in Plasma
Authors: Sarah Palmer, Ann Wiegand, Frank Maldarelli, Holly Bazmi, JoAnn M. Mican, Michael A. Polis, Robin Dewar, Angeline Planta, Shuying Liu, Julia A. Metcalf, John W. Mellors, John M. Coffin - Journal of Clinical Microbiology 2003 cited by 611
- Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control
Authors: Stephen A. Migueles, Christine Osborne, Cassandra Royce, Alex A. Compton, Rohan P. Joshi, Kristin A. Weeks, Julia E. Rood, Amy M. Berkley, Jonah B. Sacha, Nancy A. Cogliano-Shutta, Margaret Lloyd, Gregg Roby, Richard Kwan, Mary McLaughlin, Sara Stallings, Catherine Rehm, Marie A. O’Shea, JoAnn M. Mican, Beverly Z. Packard, Akira Komoriya, Sarah Palmer, Ann Wiegand, Frank Maldarelli, John M. Coffin, John W. Mellors, Claire W. Hallahan, Dean Follman, Mark Connors - Immunity 2008 cited by 593
- The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial
Authors: Rajesh T. Gandhi, Lu Zheng, Ronald J. Bosch, Ellen S. Chan, David M. Margolis, Sarah Read, Beatrice Kallungal, Sarah Palmer, Kathy Medvik, Michael M. Lederman, Nadia Alatrakchi, Jeffrey M. Jacobson, Ann Wiegand, Mary F. Kearney, John M. Coffin, John W. Mellors, Joseph J. Eron - PLoS Medicine 2010 cited by 307
- Lack of Detectable HIV-1 Molecular Evolution during Suppressive Antiretroviral Therapy
Authors: Mary F. Kearney, Jonathan Spindler, Wei Shao, Sloane Yu, Elizabeth M. Anderson, Angeline O'Shea, Catherine Rehm, Carry Poethke, N. Kovács, John W. Mellors, John M. Coffin, Frank Maldarelli - PLoS Pathogens 2014 cited by 243
- Integration in oncogenes plays only a minor role in determining the in vivo distribution of HIV integration sites before or during suppressive antiretroviral therapy
Authors: John M. Coffin, Michael J. Bale, Daria Wells, Shuang Guo, Brian T. Luke, Jennifer M. Zerbato, Michele D. Sobolewski, Twan Sia, Wei Shao, Xiaolin Wu, Frank Maldarelli, Mary F. Kearney, John W. Mellors, Stephen H. Hughes - PLoS Pathogens 2021 cited by 67
- Quantification of HIV-1 latency reversal in resting CD4 + T cells from patients on suppressive antiretroviral therapy
Authors: Anthony R. Cillo, Michele D. Sobolewski, Ronald J. Bosch, Elizabeth Fyne, Michael Piatak, John M. Coffin, John W. Mellors - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 243
- Origin of Rebound Plasma HIV Includes Cells with Identical Proviruses That Are Transcriptionally Active before Stopping of Antiretroviral Therapy
Authors: Mary F. Kearney, Ann Wiegand, Wei Shao, John M. Coffin, John W. Mellors, Michael M. Lederman, Rajesh T. Gandhi, Brandon F. Keele, Jonathan Z. Li - Journal of Virology 2015 cited by 153
- Clones of infected cells arise early in HIV-infected individuals
Authors: John M. Coffin, David W. Wells, Jennifer M. Zerbato, JoAnn Kuruc, Shuang Guo, Brian T. Luke, Joseph J. Eron, Michael J. Bale, Jonathan Spindler, Francesco R. Simonetti, Shawn Hill, Mary F. Kearney, Frank Maldarelli, Xiaolin Wu, John W. Mellors, Stephen H. Hughes - JCI Insight 2019 cited by 91
- Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction
Authors: Daniel E. Kaufmann, Daniel G. Kavanagh, Florencia Pereyra, John Zaunders, Elizabeth W. Mackey, Toshiyuki Miura, Sarah Palmer, Mark A. Brockman, Almas Rathod, Alicja Piechocka‐Trocha, B.M. Baker, Baogong Zhu, Sylvie Le Gall, Michael T. Waring, Ryan Ahern, Kristin Moss, Anthony D. Kelleher, John M. Coffin, Gordon J. Freeman, Eric Rosenberg, Bruce D. Walker - Nature Immunology 2007 cited by 513
