John R. Falck
Active 1978–2025
- 238
- Papers
- 34,968
- Citations
- 117
- h-index
- 235
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology48.7%
- Medicine30.7%
- Pharmacology, Toxicology and Pharmaceutics5%
- Chemistry4.5%
- Neuroscience3.8%
- Immunology and Microbiology2.8%
- Other4.5%
Topics
- Eicosanoids and Hypertension Pharmacology6.6%
- Pharmacogenetics and Drug Metabolism3%
- Protein Kinase Regulation and GTPase Signaling2.9%
- Cholesterol and Lipid Metabolism2.8%
- Hormonal Regulation and Hypertension2.3%
- Nitric Oxide and Endothelin Effects2.2%
- Other80.2%
Coauthors
- Jorge H. Capdevila44
- William B. Campbell25
- David R. Harder20
- Michal L. Schwartzman20
- Darryl C. Zeldin19
- John D. Imig19
- Bruce D. Hammock16
- Richard J. Roman13
- Adeniyi Michael Adebesin11
- Kasem Nithipatikom11
- Armando Karara9
- Debebe Gebremedhin9
- R. J. Roman9
- Mairéad A. Carroll8
- Nader G. Abraham8
- D. K. Barma7
- Garrett J. Gross7
- Kenneth B. Tomer7
- Komandla Malla Reddy7
- Víctor Garcia7
- Craig R. Lee6
- K. Kishta Reddy6
- Michael Balazy6
- Shouzuo Wei6
All papers
- Lysine Propionylation and Butyrylation Are Novel Post-translational Modifications in Histones
Authors: Yue Chen, Robert W. Sprung, Yi Tang, Haydn L. Ball, Bhavani Sangras, Sung Chan Kim, John R. Falck, Junmin Peng, Wei Gu, Yingming Zhao - Molecular & Cellular Proteomics 2007 cited by 764
- An oxysterol signalling pathway mediated by the nuclear receptor LXRα
Authors: Bethany A. Janowski, Patricia J. Willy, Thota Rama Devi, John R. Falck, David J. Mangelsdorf - Nature 1996 cited by 1,745
- 20-HETE Signals Through G-Protein–Coupled Receptor GPR75 (G q ) to Affect Vascular Function and Trigger Hypertension
Authors: Víctor Garcia, Ankit Gilani, Brian Shkolnik, Varunkumar Pandey, Frank Fan Zhang, Rambabu Dakarapu, Shyam K. Gandham, N. Rami Reddy, Joan P. Graves, Artiom Gruzdev, Darryl C. Zeldin, Jorge H. Capdevila, John R. Falck, Michal L. Schwartzman - Circulation Research 2017 cited by 184
- Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice
Authors: Dipak Panigrahy, Matthew L. Edin, Craig R. Lee, Sui Huang, Diane R. Bielenberg, Catherine Butterfield, Carmen M. Barnés, Akiko Mammoto, Tadanori Mammoto, A. R. Luria, Ofra Benny, Deviney M. Chaponis, Andrew C. Dudley, Emily R. Greene, Jo‐Anne Vergilio, Giorgio Pietramaggiori, Sandra S. Scherer-Pietramaggiori, Sarah M. Short, Meetu Seth, Fred B. Lih, Kenneth B. Tomer, Jun Yang, Reto A. Schwendener, Bruce D. Hammock, John R. Falck, Vijaya L. Manthati, Donald E. Ingber, Arja Kaipainen, Patrìcia A. D'Amore, Mark W. Kieran, Darryl C. Zeldin - Journal of Clinical Investigation 2011 cited by 291
- Targeting QseC Signaling and Virulence for Antibiotic Development
Authors: David A. Rasko, Cristiano G. Moreira, De Run Li, Nicola C. Reading, Jennifer M. Ritchie, Matthew K. Waldor, Noelle S. Williams, Ron Taussig, Shuguang Wei, Michael G. Roth, David T. Hughes, Jason F. Huntley, Maggy Fina, John R. Falck, Vanessa Sperandio - Science 2008 cited by 508
- Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding
Authors: Huanchen Wang, John R. Falck, Traci M. Tanaka Hall, Stephen B. Shears - Nature Chemical Biology 2011 cited by 146
- QseC Inhibitors as an Antivirulence Approach for Gram-Negative Pathogens
Authors: Meredith M. Curtis, Regan M. Russell, Cristiano G. Moreira, Adeniyi Michael Adebesin, Changguang Wang, Noelle S. Williams, Ron Taussig, Don I.H. Stewart, Philippe E. Zimmern, Biao Lu, Ravi N. Prasad, Chen Zhu, David A. Rasko, Jason F. Huntley, John R. Falck, Vanessa Sperandio - mBio 2014 cited by 137
- GPR75 receptor mediates 20-HETE-signaling and metastatic features of androgen-insensitive prostate cancer cells
Authors: Sofía Cárdenas, Cecilia Colombero, Laura Panelo, Rambabu Dakarapu, John R. Falck, Mónica A. Costas, Susana Nowicki - Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2019 cited by 44
- Epoxyeicosanoids promote organ and tissue regeneration
Authors: Dipak Panigrahy, Brian T. Kalish, Sui Huang, Diane R. Bielenberg, Hau D. Le, Jun Yang, Matthew L. Edin, Craig R. Lee, Ofra Benny, Dayna K. Mudge, Catherine Butterfield, Akiko Mammoto, Tadanori Mammoto, Bora İnceoğlu, Roger L. Jenkins, Mary Ann Simpson, Tomoshige Akino, Fred B. Lih, Kenneth B. Tomer, Donald E. Ingber, Bruce D. Hammock, John R. Falck, Vijaya L. Manthati, Arja Kaipainen, Patrìcia A. D'Amore, Mark Puder, Darryl C. Zeldin, Mark W. Kieran - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 153
- Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1
Authors: Metello Innocenti, Emanuela Frittoli, Isabella Ponzanelli, John R. Falck, Saskia M. Brachmann, Pier Paolo Di Fiore, Giorgio Scita - The Journal of Cell Biology 2003 cited by 266
- 20-Hydroxyeicosatetraenoic Acid Stimulates Nuclear Factor-κB Activation and the Production of Inflammatory Cytokines in Human Endothelial Cells
Authors: Tsuneo Ishizuka, Jennifer Cheng, Harpreet Singh, M. Del Vitto, Vijay L. Manthati, John R. Falck, Michal L. Schwartzman - Journal of Pharmacology and Experimental Therapeutics 2007 cited by 179
- The Diadenosine Hexaphosphate Hydrolases fromSchizosaccharomyces pombe and Saccharomyces cerevisiae Are Homologues of the Human Diphosphoinositol Polyphosphate Phosphohydrolase
Authors: Stephen T. Safrany, Stephen W. Ingram, Jared Cartwright, John R. Falck, Alexander G. McLennan, Larry D. Barnes, Stephen B. Shears - Journal of Biological Chemistry 1999 cited by 148
- Cytochrome P450 and arachidonic acid bioactivation: molecular and functional properties of the arachidonate monooxygenase
Authors: Jorge H. Capdevila, John R. Falck, Raymond C. Harris - Journal of Lipid Research 2000 cited by 555
- Direct Stereospecific Synthesis of Unprotected N-H and N-Me Aziridines from Olefins
Authors: Jawahar L. Jat, Mahesh P. Paudyal, Hongyin Gao, Qing-Long Xu, Muhammed Yousufuddin, Deepa Devarajan, Daniel H. Ess, László Kürti, John R. Falck - Science 2014 cited by 334
- Requirement of Inositol Pyrophosphates for Full Exocytotic Capacity in Pancreatic β Cells
Authors: Christopher Illies, Jesper Gromada, Roberta Fiume, Barbara Leibiger, Jia Yu, Kirstine Juhl, Shao-Nian Yang, D. K. Barma, John R. Falck, Adolfo Saiardi, Christopher J. Barker, Per‐Olof Berggren - Science 2007 cited by 189
- Characterization of 5,6- and 8,9-Epoxyeicosatrienoic Acids (5,6- and 8,9-EET) as Potent in Vivo Angiogenic Lipids
Authors: Ambra Pozzi, Ines Macias‐Perez, Tristin D. Abair, Shouzuo Wei, Su Yan, Roy Zent, John R. Falck, Jorge H. Capdevila - Journal of Biological Chemistry 2005 cited by 181
- CYP3A4 Mediates Growth of Estrogen Receptor-positive Breast Cancer Cells in Part by Inducing Nuclear Translocation of Phospho-Stat3 through Biosynthesis of (±)-14,15-Epoxyeicosatrienoic Acid (EET)
Authors: Ranjana Mitra, Zhijun Guo, Monica Milani, Clementina Mesaros, Mariangellys Rodriguez, Julia Nguyen, Xianghua Luo, Duncan J. Clarke, Jatinder K. Lamba, Erin G. Schuetz, David B. Donner, P. Narender, John R. Falck, Jorge H. Capdevila, Kalpna Gupta, Ian A. Blair, David A. Potter - Journal of Biological Chemistry 2011 cited by 118
- Functional characterization of cytochrome P450-derived epoxyeicosatrienoic acids in adipogenesis and obesity
Authors: Weibin Zha, Matthew L. Edin, Kimberly C. Vendrov, Robert N. Schuck, Fred B. Lih, Jawahar L. Jat, J. Alyce Bradbury, Laura M. DeGraff, Kunjie Hua, Kenneth B. Tomer, John R. Falck, Darryl C. Zeldin, Craig R. Lee - Journal of Lipid Research 2014 cited by 87
- EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides
Authors: Martina Decker, Magdalena Adamska, Annette Cronin, Francesca Di Giallonardo, Julia Burgener, Anne Marowsky, John R. Falck, Christophe Morisseau, Bruce D. Hammock, Artiom Gruzdev, Darryl C. Zeldin, Michael Arand - Journal of Lipid Research 2012 cited by 87
- Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer
Authors: Wei Yu, Hongyan Chai, Ying Li, Haixia Zhao, Xianfei Xie, Hao Zheng, Chenlong Wang, Xue Wang, Guifang Yang, Xiaojun Cai, John R. Falck, Jing Yang - Toxicology and Applied Pharmacology 2012 cited by 86
- Uncovering the signalling, structure and function of the 20‐HETE‐GPR75 pairing: Identifying the chemokine CCL5 as a negative regulator of GPR75
Authors: Jonathan V. Pascale, Eon Joo Park, Adeniyi Michael Adebesin, John R. Falck, Michal L. Schwartzman, Víctor Garcia - British Journal of Pharmacology 2021 cited by 55
- 20-Hydroxyeicosatetraenoic acid (20-HETE): Bioactions, receptors, vascular function, cardiometabolic disease and beyond
Authors: Jonathan V. Pascale, Alexandra Wolf, Yonaton Kadish, Danielle Diegisser, Melissa-Maria Kulaprathazhe, Danait Yemane, Samir Ali, Nam‐Hee Kim, David E. Baruch, M. A. F. Yahaya, Ercument Dirice, Adeniyi Michael Adebesin, John R. Falck, Michal L. Schwartzman, Víctor Garcia - Advances in pharmacology 2023 cited by 24
- The Highly Stereoselective Oxidation of Polyunsaturated Fatty Acids by Cytochrome P450BM-3
Authors: Jorge H. Capdevila, Shozou Wei, Christian Helvig, John R. Falck, Yuri Belosludtsev, Gilles Truan, Sandra E. Graham-Lorence, Julian A. Peterson - Journal of Biological Chemistry 1996 cited by 180
- Cytochrome P450 epoxygenases 2C8 and 2C9 are implicated in hypoxia-induced endothelial cell migration and angiogenesis
Authors: Uwe Michaelis, Beate Fißlthaler, Eduardo Barbosa‐Sicard, John R. Falck, Ingrid Fleming, Rudi Busse - Journal of Cell Science 2005 cited by 171
