Joseph R. Testa
Active 1978–2024
- 153
- Papers
- 36,303
- Citations
- 98
- h-index
- 150
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology47.3%
- Medicine45.3%
- Immunology and Microbiology3.2%
- Neuroscience0.9%
- Computer Science0.8%
- Nursing0.5%
- Other2%
Topics
- PI3K/AKT/mTOR signaling in cancer4.3%
- Ovarian cancer diagnosis and treatment4%
- Cancer Genomics and Diagnostics2.8%
- PARP inhibition in cancer therapy2.6%
- RNA modifications and cancer2%
- Cancer-related Molecular Pathways2%
- Other82.3%
Coauthors
- Deborah A. Altomare20
- Alfonso Bellacosa15
- Mitchell Cheung15
- Andrew K. Godwin14
- Andres J. Klein–Szanto13
- Jianming Pei13
- Michele Carbone13
- Craig W. Menges11
- Gonosuke Sonoda10
- Eleonora Sementino9
- Suresh C. Jhanwar9
- Daphne W. Bell8
- Harvey I. Pass8
- Jacqueline Talarchek8
- Kathy Q. Cai8
- Thomas C. Hamilton8
- Yuwaraj Kadariya8
- Assunta De Rienzo7
- Guang‐Hui Xiao7
- Yinfei Tan7
- Brooke T. Mossman6
- Kristine L. Skele6
- Takahiro Taguchi6
- Yasuhiro Mitsuuchi6
All papers
- Integrated genomic analyses of ovarian carcinoma
Authors: Debra Bell, Andrew Berchuck, Andrew Berchuck, Michael J. Birrer, Marcin Imieliński, Michael J. Birrer, Jeremy Chien, D. W. Cramer, Narciso Olvera, Fanny Dao, P. DiSaia, H. Gabra, Rajiv Dhir, Philip J. DiSaia, Hani Gabra, Karen Smith‐McCune, Pat Glenn, A. K. Godwin, Sandra Oršulić, Beth Y. Karlan, Jenny Gross, L Hartmann, Mei Huang, David G. Huntsman, Steve E. Kalloger, Brenda Rabeno, Mary Iacocca, Beth Y. Karlan, G.B. Mills, N. Petrelli, J. S. Rader, G.B. Mills, A. K. Sood, D. Bowtell, R. Penny, T. Shelton, Kay J. Park, Nicholas J. Petrelli, Janet S. Rader, Branimir I. Šikić, Anil K. Sood, Anil K. Sood, David D.L. Bowtell, Scott Morris, Peggy Yena, Michael J Hatfield, Joseph Paulauskis, Troy Shelton, Robert Penny, Paul Rhodes, Robert Penny, Mark E. Sherman, Donata Grimm, Sherri Z. Millis, Joseph R. Testa, David A. Wheeler, Lora Lewis, J. G. Reid, Jennifer Drummond, Irene Newsham, M. B. Morgan, Jireh Santibanez, C. Kovar, Huyen Dinh, Kuo-Ching Chang, Lisa R. Treviño, K. Cibulskis, Richard A. Gibbs, Preethi H. Gunaratne, Gerald Fowler, M. Wang, Alicia Hawes, Donna M. Muzny, J. G. Reid, C. H. Mermel, Matthew Meyerson, Andrey Sivachenko, R. C. Onofrio, Alex H. Ramos, Andrey Sivachenko, A. Crenshaw, R. W. Park, S. L. Carter, Robert C. Onofrio, Gordon Saksena, Eric S. Lander, L. Chin, Andrew Crenshaw, Kristin Ardlie, Gaddy Getz, Huy Nguyen, R. Nichol, Michael S. Lawrence, Douglas Voet, Sumeet Gupta, Rui Jing, Mike Noble, Diana Hubbard, D. C. Koboldt, Kristian Cibulskis and 155 more - Nature 2011 cited by 8,222
- The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells
Authors: Alison Kurimchak, Carlos Herrera-Montávez, Sara Montserrat‐Sangrà, Daniela Araiza‐Olivera, Jianping Hu, Ryan Neumann-Domer, Mathew Kuruvilla, Alfonso Bellacosa, Joseph R. Testa, Jian Jin, James S. Duncan - Science Signaling 2022 cited by 107
- BAP1 and cancer
Authors: Michele Carbone, Haining Yang, Harvey I. Pass, Thomas Krausz, Joseph R. Testa, Giovanni Gaudino - Nature reviews. Cancer 2013 cited by 665
- Perturbations of the AKT signaling pathway in human cancer
Authors: Deborah A. Altomare, Joseph R. Testa - Oncogene 2005 cited by 1,324
- Germline BAP1 mutations predispose to malignant mesothelioma
Authors: Joseph R. Testa, Mitchell Cheung, Jianming Pei, Jennifer E. Below, Yinfei Tan, Eleonora Sementino, Nancy J. Cox, A. Umran Doğan, Harvey I. Pass, Sandra Trusa, Mary Hesdorffer, Masaki Nasu, Amy Powers, Zeyana Rivera, Sabahattin Cömertpay, Mika Tanji, Giovanni Gaudino, Haining Yang, Michele Carbone - Nature Genetics 2011 cited by 1,075
- Comprehensive Study of the Clinical Phenotype of GermlineBAP1Variant-Carrying Families Worldwide
Authors: Sebastian Walpole, Antonia L. Pritchard, Colleen M. Cebulla, Robert Pilarski, Meredith Stautberg, Frederick H. Davidorf, Arnaud de la Fouchardière, Odile Cabaret, Lisa Golmard, Dominique Stoppa‐Lyonnet, Erin M. Garfield, Ching-Ni Jenny Njauw, Mitchell Cheung, Joni A. Turunen, Pauliina Repo, Reetta-Stiina Järvinen, Remco van Doorn, Martine J. Jager, Gregorius P. M. Luyten, Marina Marinkovic, Cindy Chau, Míriam Potrony, Veronica Höiom, Hildur Helgadóttir, Lorenza Pastorino, William Bruno, Virginia Andreotti, Bruna Dalmasso, Giulia Ciccarese, Paola Queirolo, Luca Mastracci, Karin Wadt, Jens Folke Kiilgaard, Michael R. Speicher, Natasha M. van Poppelen, Emine Kılıç, Rana’a T. Al‐Jamal, Irma Dianzani, Marta Betti, Carsten Bergmann, Sandro Santagata, Sonika Dahiya, Saleem Taibjee, Jo Burke, Nicola Poplawski, Sally J. O’Shea, Julia Newton‐Bishop, Julian Adlard, David J. Adams, Anne-Marie Lane, Ivana K. Kim, Sonja Klebe, Hilary Racher, J. William Harbour, Michael L. Nickerson, Rajmohan Murali, Jane M. Palmer, Madeleine Howlie, Judith Symmons, Hayley R. Hamilton, Sunil Warrier, William Glasson, Peter A. Johansson, Carla Daniela Robles‐Espinoza, Raúl Ossio, Annelies de Klein, Susana Puig, Paola Ghiorzo, Maartje Nielsen, Tero Kivelä, Hensin Tsao, Joseph R. Testa, Pedram Gerami, Marc‐Henri Stern, Brigitte Bressac–de Paillerets, Mohamed H. Abdel‐Rahman, Nicholas K. Hayward - JNCI Journal of the National Cancer Institute 2018 cited by 241
- AKT plays a central role in tumorigenesis
Authors: Joseph R. Testa, Alfonso Bellacosa - National Academy of Sciences, Proceedings of the National Academy of Sciences 2001 cited by 940
- Activation of AKT Kinases in Cancer: Implications for Therapeutic Targeting
Authors: Alfonso Bellacosa, C. Chandra Kumar, Antonio Di Cristofano, Joseph R. Testa - Advances in cancer research 2005 cited by 824
- BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance
Authors: Joseph Nacson, John J. Krais, Andrea J. Bernhardy, Emma Clausen, Wanjuan Feng, Yifan Wang, Émmanuelle Nicolas, Kathy Q. Cai, Rossella Tricarico, Hua Xiang, Daniela Di Marcantonio, Esteban Martı́nez, Dali Zong, Elizabeth A. Handorf, Alfonso Bellacosa, Joseph R. Testa, André Nussenzweig, Gaorav P. Gupta, Stephen M. Sykes, Neil Johnson - Cell Reports 2018 cited by 98
- Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma
Authors: Yinfei Tan, Eleonora Sementino, Mitchell Cheung, Suraj Peri, Craig W. Menges, Anna-Mariya Kukuyan, Ting Zhang, Vladimir Khazak, Lauren A. Fox, Eric A. Ross, Suresh Y. Ramanathan, Suresh C. Jhanwar, Raja M. Flores, Siddharth Balachandran, Joseph R. Testa - Clinical Cancer Research 2020 cited by 68
- Genetic Dissection of the Oncogenic mTOR Pathway Reveals Druggable Addiction to Translational Control via 4EBP-eIF4E
Authors: Andrew C. Hsieh, Maria Da Costa, Ornella Zollo, Cole Davis, Morris E. Feldman, Joseph R. Testa, Oded Meyuhas, Kevan M. Shokat, Davide Ruggero - Cancer Cell 2010 cited by 462
- Merlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship
Authors: Irina M. Shapiro, Vihren N. Kolev, Christian M. Vidal, Yuwaraj Kadariya, Jennifer E. Ring, Quentin G. Wright, David T. Weaver, Craig W. Menges, Mahesh V. Padval, Andrea I. McClatchey, Qunli Xu, Joseph R. Testa, Jonathan A. Pachter - Science Translational Medicine 2014 cited by 244
- Asbestos and Other Hazardous Fibrous Minerals: Potential Exposure Pathways and Associated Health Risks
Authors: Terri-Ann Berry, Elena Belluso, Ruggero Vigliaturo, Reto Gieré, Edward A. Emmett, Joseph R. Testa, Gregor Steinhorn, Shannon Wallis - International Journal of Environmental Research and Public Health 2022 cited by 67
- RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance
Authors: Shuyun Rao, Suraj Peri, Jens Hoffmann, Kathy Q. Cai, Bryan Harris, Michele Rhodes, Denise C. Connolly, Joseph R. Testa, David L. Wiest - PLoS ONE 2019 cited by 57
- Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas
Authors: Alfonso Bellacosa, Daniela de Feo, Andrew K. Godwin, Daphne W. Bell, Jin Q. Cheng, Deborah A. Altomare, Minghong Wan, Louis Dubeau, Giovanni Scambia, Valeria Masciullo, Gabriella Ferrandina, Pierluigi Benedetti Panici, Salvatore Mancuso, Giovanni Neri, Joseph R. Testa - International Journal of Cancer 1995 cited by 836
- Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.
Authors: Jin Q. Cheng, Bruce Ruggeri, Willemijn M. Klein, Gonosuke Sonoda, Deborah A. Altomare, Dennis K. Watson, Joseph R. Testa - National Academy of Sciences, Proceedings of the National Academy of Sciences 1996 cited by 793
- PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth
Authors: Weijia Cai, Liya Su, Lili Liao, Zongzhi Liu, Lauren Langbein, Essel Dulaimi, Joseph R. Testa, Robert G. Uzzo, Zhijiu Zhong, Wei Jiang, Qin Yan, Qing Zhang, Haifeng Yang - Nature Communications 2019 cited by 79
- AKT kinases as therapeutic targets
Authors: Dalal Hassan, Craig W. Menges, Joseph R. Testa, Alfonso Bellacosa - Journal of Experimental & Clinical Cancer Research 2024 cited by 51
- A review of neoplasms with MITF/MiT family translocations.
Authors: Shuanzeng Wei, Joseph R. Testa, Pedram Argani - 2022 cited by 33
- NEAT1-TFE3 and KAT6A-TFE3 renal cell carcinomas, new members of MiT family translocation renal cell carcinoma
Authors: Jianming Pei, Harry S. Cooper, Douglas B. Flieder, Jacqueline Talarchek, Tahseen Al‐Saleem, Robert G. Uzzo, Essel Dulaimi, Arthur S. Patchefsky, Joseph R. Testa, Shuanzeng Wei - Modern Pathology 2019 cited by 79
- BAP1, a tumor suppressor gene driving malignant mesothelioma
Authors: Mitchell Cheung, Joseph R. Testa - Translational Lung Cancer Research 2017 cited by 76
- Papillary Renal Neoplasm With Reverse Polarity Is Often Cystic: Report of 7 Cases and Review of 93 Cases in the Literature.
Authors: Shuanzeng Wei, Alexander Kutikov, Arthur S Patchefsky, Douglas B. Flieder, Jacqueline Talarchek, Tahseen Al-Saleem, Essel Dulaimi, Robert G. Uzzo, Joseph R. Testa, Jianming Pei - The American Journal of Surgical Pathology 2021 cited by 49
- Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities
Authors: John J. Krais, David J. Glass, Ilse Chudoba, Yifan Wang, Wanjuan Feng, Dennis A. Simpson, Pooja Patel, Zemin Liu, Ryan Neumann-Domer, Robert Betsch, Andrea J. Bernhardy, Alice Bradbury, Jason Conger, Wei-Ting Yueh, Joseph Nacson, Richard T. Pomerantz, Gaorav P. Gupta, Joseph R. Testa, Neil Johnson - Nature Communications 2023 cited by 25
- Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways
Authors: Guang‐Hui Xiao, Michael Jeffers, Alfonso Bellacosa, Yasuhiro Mitsuuchi, George F. Vande Woude, Joseph R. Testa - National Academy of Sciences, Proceedings of the National Academy of Sciences 2000 cited by 396
