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Ken J. Ishii

Active 1998–2025

135
Papers
28,753
Citations
82
h-index
131
i10-index

Citations

Citations per year for Ken J. Ishii1970: 1 citations1998: 3 citations1999: 7 citations2000: 20 citations2001: 20 citations2002: 63 citations2003: 87 citations2004: 107 citations2005: 221 citations2006: 394 citations2007: 497 citations2008: 539 citations2009: 645 citations2010: 548 citations2011: 519 citations2012: 463 citations2013: 435 citations2014: 404 citations2015: 338 citations2016: 307 citations2017: 326 citations2018: 286 citations2019: 797 citations2020: 904 citations2021: 894 citations2022: 793 citations2023: 603 citations2024: 786 citations2025: 434 citations2026: 8 citations1971–1997: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,634 citing papers, 28.4% of this breakdownChina: 1,799 citing papers, 14.1% of this breakdownJapan: 1,041 citing papers, 8.1% of this breakdownGermany: 712 citing papers, 5.6% of this breakdownUnited Kingdom: 698 citing papers, 5.4% of this breakdownFrance: 499 citing papers, 3.9% of this breakdownCanada: 411 citing papers, 3.2% of this breakdownAustralia: 288 citing papers, 2.2% of this breakdownItaly: 277 citing papers, 2.2% of this breakdownSwitzerland: 230 citing papers, 1.8% of this breakdownSouth Korea: 228 citing papers, 1.8% of this breakdownIndia: 222 citing papers, 1.7% of this breakdown
0%28.4%Other 21.6%

Institutions

Fields

  • Immunology and Microbiology47.5%
  • Medicine27.4%
  • Biochemistry, Genetics and Molecular Biology18.9%
  • Agricultural and Biological Sciences1.7%
  • Neuroscience1.4%
  • Materials Science0.7%
  • Other2.4%

Topics

  • interferon and immune responses11.1%
  • Immune Response and Inflammation8.9%
  • Immunotherapy and Immune Responses4.5%
  • Immune Cell Function and Interaction4.5%
  • Inflammasome and immune disorders3.6%
  • Viral Infections and Vectors2.6%
  • Other64.8%

Coauthors

All papers

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  1. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

    Authors: Hiroki Kato, Osamu Takeuchi, Shintaro Sato, Mitsutoshi Yoneyama, Masahiro Yamamoto, Kosuke Matsui, Satoshi Uematsu, Andreas Jung, Taro Kawai, Ken J. Ishii, Osamu Yamaguchi, Kinya Otsu, Tohru Tsujimura, Chang‐Sung Koh, Caetano Reis e Sousa, Yoshiharu Matsuura, Takashi Fujita, Shizuo Akira - Nature 2006 cited by 3,873

  2. Challenges in developing personalized neoantigen cancer vaccines

    Authors: Peter D. Katsikis, Ken J. Ishii, Christopher Schliehe - Nature reviews. Immunology 2023 cited by 227

  3. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

    Authors: Taro Kawai, Ken Takahashi, Shintaro Sato, Cevayir Coban, Himanshu Kumar, Hiroki Kato, Ken J. Ishii, Osamu Takeuchi, Shizuo Akira - Nature Immunology 2005 cited by 2,544

  4. DNA-Containing Exosomes Derived from Cancer Cells Treated with Topotecan Activate a STING-Dependent Pathway and Reinforce Antitumor Immunity

    Authors: Yuichi Kitai, Takumi Kawasaki, Takuya Sueyoshi, Kouji Kobiyama, Ken J. Ishii, Jian Zou, Shizuo Akira, Tadashi Matsuda, Taro Kawai - The Journal of Immunology 2017 cited by 310

  5. Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

    Authors: Tatsuya Saitoh, Naonobu Fujita, Takuya Hayashi, Keigo Takahara, Takashi Satoh, Hanna Lee, Kohichi Matsunaga, Shun Kageyama, Hiroko Omori, Takeshi Noda, Naoki Yamamoto, Taro Kawai, Ken J. Ishii, Osamu Takeuchi, Tamotsu Yoshimori, Shizuo Akira - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 cited by 839

  6. Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike

    Authors: Daichi Yamasoba, Izumi Kimura, Hesham Nasser, Yuhei Morioka, Naganori Nao, Jumpei Ito, Keiya Uriu, Masumi Tsuda, Jiří Zahradník, Kotaro Shirakawa, Rigel Suzuki, Mai Kishimoto, Yusuke Kosugi, Kouji Kobiyama, Teppei Hara, Mako Toyoda, Yuri Tanaka, Erika P. Butlertanaka, Ryo Shimizu, Hayato Ito, Lei Wang, Yoshitaka Oda, Yasuko Orba, Michihito Sasaki, Kayoko Nagata, Kumiko Yoshimatsu, Hiroyuki Asakura, Mami Nagashima, Kenji Sadamasu, Kazuhisa Yoshimura, Jin Kuramochi, M. Seki, Ryoji Fujiki, Atsushi Kaneda, Tadanaga Shimada, Taka‐aki Nakada, Seiichiro Sakao, Takuji Suzuki, Takamasa Ueno, Akifumi Takaori‐Kondo, Ken J. Ishii, Gideon Schreiber, Hirofumi Sawa, Akatsuki Saito, Takashi Irie, Shinya Tanaka, Keita Matsuno, Takasuke Fukuhara, Terumasa Ikeda, Kei Sato - Cell 2022 cited by 352

  7. Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5

    Authors: Izumi Kimura, Daichi Yamasoba, Tomokazu Tamura, Naganori Nao, Tateki Suzuki, Yoshitaka Oda, Shuya Mitoma, Jumpei Ito, Hesham Nasser, Jiří Zahradník, Keiya Uriu, Shigeru Fujita, Yusuke Kosugi, Lei Wang, Masumi Tsuda, Mai Kishimoto, Hayato Ito, Rigel Suzuki, Ryo Shimizu, MST Monira Begum, Kumiko Yoshimatsu, Kanako Kimura, Jiei Sasaki, Kaori Sasaki‐Tabata, Yuki Yamamoto, Tetsuharu Nagamoto, Jun Kanamune, Kouji Kobiyama, Hiroyuki Asakura, Mami Nagashima, Kenji Sadamasu, Kazuhisa Yoshimura, Kotaro Shirakawa, Akifumi Takaori‐Kondo, Jin Kuramochi, Gideon Schreiber, Ken J. Ishii, Takao Hashiguchi, Terumasa Ikeda, Akatsuki Saito, Takasuke Fukuhara, Shinya Tanaka, Keita Matsuno, Kei Sato - Cell 2022 cited by 297

  8. Innate immune response to viral infection

    Authors: Shohei Koyama, Ken J. Ishii, Cevayir Coban, Shizuo Akira - Cytokine 2008 cited by 464

  9. Making innate sense of mRNA vaccine adjuvanticity

    Authors: Kouji Kobiyama, Ken J. Ishii - Nature Immunology 2022 cited by 109

  10. Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

    Authors: Taro Kawai, Shintaro Sato, Ken J. Ishii, Cevayir Coban, Hiroaki Hemmi, Masahiro Yamamoto, Kenta Terai, Michiyuki Matsuda, Jun‐ichiro Inoue, Satoshi Uematsu, Osamu Takeuchi, Shizuo Akira - Nature Immunology 2004 cited by 1,013

  11. Secretion of mitochondrial DNA via exosomes promotes inflammation in Behçet's syndrome

    Authors: Hachiro Konaka, Yasuhiro Kato, Tôru Hirano, Kohei Tsujimoto, JeongHoon Park, Taro Koba, Wataru Aoki, Yusei Matsuzaki, Masayasu Taki, Shohei Koyama, Eri Itotagawa, Tatsunori Jo, Takehiro Hirayama, Taro Kawai, Ken J. Ishii, Mitsuyoshi Ueda, Shigehiro Yamaguchi, Shizuo Akira, Takayoshi Morita, Yuichi Maeda, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Hyota Takamatsu, Atsushi Kumanogoh - The EMBO Journal 2023 cited by 43

  12. Genome-Derived Cytosolic DNA Mediates Type I Interferon-Dependent Rejection of B Cell Lymphoma Cells

    Authors: Yu J. Shen, Nina Le Bert, Anuja Chitre, Christine X. Koo, Xing H Nga, Samantha S.W. Ho, Muznah Khatoo, Nikki Yi Jie Tan, Ken J. Ishii, Stephan Gasser - Cell Reports 2015 cited by 182

  13. RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma

    Authors: Adeline R. Lam, Nina Le Bert, Samantha S.W. Ho, Yu J. Shen, Melissa L.F. Tang, Gordon M. Xiong, J. Ludovic Croxford, Christine X. Koo, Ken J. Ishii, Shizuo Akira, David H. Raulet, Stephan Gasser - Cancer Research 2014 cited by 175

  14. Exploring the relationship between anti-PEG IgM behaviors and PEGylated nanoparticles and its significance for accelerated blood clearance

    Authors: Kouichi Shiraishi, K. Kawano, Yoshie Maitani, Taiki Aoshi, Ken J. Ishii, Y. Sanada, Shinichi Mochizuki, Kazuo Sakurai, Masayuki Yokoyama - Journal of Controlled Release 2016 cited by 88

  15. TLR9 and STING agonists synergistically induce innate and adaptive type‐II IFN

    Authors: Burcu Temizoz, Etsushi Kuroda, Keiichi Ohata, Nao Jounai, Koji Ozasa, Kouji Kobiyama, Taiki Aoshi, Ken J. Ishii - European Journal of Immunology 2014 cited by 152

  16. Interleukin-1/-33 Signaling Pathways as Therapeutic Targets for Endometriosis

    Authors: Toru Kato, Koubun Yasuda, Kazufumi Matsushita, Ken J. Ishii, Seiichi Hirota, Tomohiro Yoshimoto, Hiroaki Shibahara - Frontiers in Immunology 2019 cited by 64

  17. TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

    Authors: Ken J. Ishii, Tatsukata Kawagoe, Shohei Koyama, Kosuke Matsui, Himanshu Kumar, Taro Kawai, Satoshi Uematsu, Osamu Takeuchi, Fumihiko Takeshita, Cevayir Coban, Shizuo Akira - Nature 2008 cited by 624

  18. Host Innate Immune Receptors and Beyond: Making Sense of Microbial Infections

    Authors: Ken J. Ishii, Shohei Koyama, Atsushi Nakagawa, Cevayir Coban, Shizuo Akira - Cell Host & Microbe 2008 cited by 497

  19. DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

    Authors: Takeshi Kondo, Junya Kobayashi, Tatsuya Saitoh, Kenta Maruyama, Ken J. Ishii, Glen N. Barber, Kenshi Komatsu, Shizuo Akira, Taro Kawai - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 339

  20. A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP

    Authors: Sarah M. McWhirter, Roman Barbalat, Kathryn M. Monroe, Mary F. Fontana, Mamoru Hyodo, Nathalie T. Joncker, Ken J. Ishii, Shizuo Akira, Marco Colonna, Zhijian J. Chen, Katherine A. Fitzgerald, Yoshihiro Hayakawa, Russell E. Vance - The Journal of Experimental Medicine 2009 cited by 296

  21. Hydrophobic blocks of PEG-conjugates play a significant role in the accelerated blood clearance (ABC) phenomenon

    Authors: Kouichi Shiraishi, Mikiko Hamano, Huili Ma, K. Kawano, Yoshie Maitani, Taiki Aoshi, Ken J. Ishii, Masayuki Yokoyama - Journal of Controlled Release 2012 cited by 139

  22. Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5

    Authors: Satoshi Uematsu, Kosuke Fujimoto, Myoung Ho Jang, Bo‐Gie Yang, Yun-Jae Jung, Mika Nishiyama, Shintaro Sato, Tohru Tsujimura, Masafumi Yamamoto, Yoshifumi Yokota, Hiroshi Kiyono, Masayuki Miyasaka, Ken J. Ishii, Shizuo Akira - Nature Immunology 2008 cited by 725

  23. DNA released from dying host cells mediates aluminum adjuvant activity

    Authors: Thomas Marichal, Keiichi Ohata, Denis Bedoret, Claire Mesnil, Catherine Sabatel, Kouji Kobiyama, Pierre Lekeux, Cevayir Coban, Shizuo Akira, Ken J. Ishii, Fabrice Bureau, Christophe Desmet - Nature Medicine 2011 cited by 524

  24. Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination

    Authors: Christophe Desmet, Ken J. Ishii - Nature reviews. Immunology 2012 cited by 389