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Lee J. Helman

Active 1977–2023

105
Papers
20,221
Citations
83
h-index
105
i10-index

Citations

Citations per year for Lee J. Helman1978: 1 citations1979: 1 citations1981: 1 citations1982: 1 citations1983: 1 citations1986: 1 citations1987: 1 citations1989: 8 citations1990: 10 citations1991: 21 citations1992: 29 citations1993: 23 citations1994: 26 citations1995: 21 citations1996: 38 citations1997: 47 citations1998: 38 citations1999: 34 citations2000: 40 citations2001: 36 citations2002: 52 citations2003: 64 citations2004: 91 citations2005: 120 citations2006: 148 citations2007: 164 citations2008: 194 citations2009: 217 citations2010: 221 citations2011: 235 citations2012: 224 citations2013: 238 citations2014: 225 citations2015: 221 citations2016: 165 citations2017: 180 citations2018: 151 citations2019: 576 citations2020: 511 citations2021: 496 citations2022: 394 citations2023: 309 citations2024: 426 citations2025: 191 citations2026: 3 citations1980: no citations, so this year is not shown1984–1985: no citations, so these years are not shown1988: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,654 citing papers, 35.8% of this breakdownChina: 765 citing papers, 10.3% of this breakdownUnited Kingdom: 441 citing papers, 5.9% of this breakdownItaly: 392 citing papers, 5.3% of this breakdownGermany: 320 citing papers, 4.3% of this breakdownFrance: 289 citing papers, 3.9% of this breakdownCanada: 275 citing papers, 3.7% of this breakdownJapan: 236 citing papers, 3.2% of this breakdownNetherlands: 205 citing papers, 2.8% of this breakdownSpain: 180 citing papers, 2.4% of this breakdownAustralia: 170 citing papers, 2.3% of this breakdownSwitzerland: 149 citing papers, 2% of this breakdown
0%35.8%Other 18.1%

Institutions

Fields

  • Medicine57%
  • Biochemistry, Genetics and Molecular Biology32.9%
  • Immunology and Microbiology6.4%
  • Engineering1.1%
  • Neuroscience0.7%
  • Chemistry0.3%
  • Other1.6%

Topics

  • Sarcoma Diagnosis and Treatment6.8%
  • CAR-T cell therapy research4.4%
  • Immunotherapy and Immune Responses3.5%
  • Cancer, Hypoxia, and Metabolism3.4%
  • Epigenetics and DNA Methylation2.1%
  • Immune Cell Function and Interaction2%
  • Other77.8%

Coauthors

All papers

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  1. New Horizons in the Treatment of Osteosarcoma

    Authors: Paul S. Meltzer, Lee J. Helman - New England Journal of Medicine 2021 cited by 651

  2. Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1

    Authors: Paul F. Robbins, Richard A. Morgan, Steven A. Feldman, James C. Yang, Richard M. Sherry, Mark E. Dudley, John R. Wunderlich, Azam Nahvi, Lee J. Helman, Crystal L. Mackall, Udai S. Kammula, Marybeth S. Hughes, Nicholas P. Restifo, Mark Raffeld, Chyi‐Chia Richard Lee, Catherine Lévy, Yong F. Li, Mona El‐Gamil, Susan Schwarz, Carolyn M. Laurençot, Steven A. Rosenberg - Journal of Clinical Oncology 2011 cited by 1,610

  3. Molecular Subtypes ofKIT/PDGFRAWild-Type Gastrointestinal Stromal Tumors

    Authors: Sosipatros A. Boikos, Alberto S. Pappo, J. Keith Killian, Michael P. LaQuaglia, Chris B. Weldon, Suzanne George, Jonathan C. Trent, Margaret von Mehren, Jennifer Wright, J. D. Schiffman, Margarita Raygada, Karel Pacák, Paul S. Meltzer, Markku Miettinen, Constantine A. Stratakis, Katherine A. Janeway, Lee J. Helman - JAMA Oncology 2016 cited by 407

  4. Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models

    Authors: James G. Taylor, Adam Cheuk, Patricia Tsang, Joon‐Yong Chung, Young Song, Krupa Desai, Yanlin Yu, Qingrong Chen, Kushal Shah, Victoria Youngblood, Jun Fang, Su Young Kim, Choh Yeung, Lee J. Helman, Arnulfo Mendoza, Vu N. Ngo, Louis M. Staudt, Jun S. Wei, Chand Khanna, Daniel Catchpoole, Stephen J. Qualman, Stephen M. Hewitt, Glenn Merlino, Stephen J. Chanock, Javed Khan - Journal of Clinical Investigation 2009 cited by 322

  5. Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma

    Authors: Choh Yeung, Anna E. Gibson, Sameer H. Issaq, Nobu Oshima, Joshua T. Baumgart, Leah D. Edessa, Ganesha Rai, Daniel J. Urban, Michelle S. Johnson, Gloria A. Benavides, Giuseppe L. Squadrito, Marielle E. Yohe, Haiyan Lei, Sandy Eldridge, John Hamre, Tyrone Dowdy, Victor Ruiz‐Rodado, Adrian Lita, Arnulfo Mendoza, Jack F. Shern, Mioara Larion, Lee J. Helman, Gordon M. Stott, Murali C. Krishna, Matthew D. Hall, Victor Darley‐Usmar, Leonard Μ. Neckers, Christine M. Heske - Cancer Research 2019 cited by 130

  6. Succinate Dehydrogenase Mutation Underlies Global Epigenomic Divergence in Gastrointestinal Stromal Tumor

    Authors: Jonathan Keith Killian, Su Young Kim, Markku Miettinen, Carly Smith, Maria J. Merino, Maria Tsokos, Martha Quezado, William I. Smith, Mona S. Jahromi, Paraskevi Xekouki, Eva Szarek, Robert L. Walker, Jerzy Lasota, Mark Raffeld, Brandy Klotzle, Zengfeng Wang, Laura Jones, Yuelin J. Zhu, Yonghong Wang, Joshua J. Waterfall, Maureen J. O’Sullivan, Marina Bibikova, Karel Pacák, Constantine A. Stratakis, Katherine A. Janeway, Joshua D. Schiffman, Jian-Bing Fan, Lee J. Helman, Paul S. Meltzer - Cancer Discovery 2013 cited by 355

  7. Positively selected enhancer elements endow osteosarcoma cells with metastatic competence

    Authors: James J. Morrow, Ian Bayles, Alister P. W. Funnell, Tyler E. Miller, Alina Saiakhova, Michael M. Lizardo, Cynthia F. Bartels, Maaike Y. Kapteijn, Stevephen Hung, Arnulfo Mendoza, Gursimran Dhillon, Daniel R. Chee, Jay Myers, Frederick H. Allen, Marco Gambarotti, Alberto Righi, Analisa DiFeo, Brian P. Rubin, Alex Y. Huang, Paul S. Meltzer, Lee J. Helman, Piero Picci, Henri H. Versteeg, J Stamatoyannopoulos, Chand Khanna, Peter C. Scacheri - Nature Medicine 2018 cited by 173

  8. Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations

    Authors: Katherine A. Janeway, Su Young Kim, Maya Lodish, Vânia Nosé, Pierre Rustin, José Gaal, Patricia L. M. Dahia, Bernadette Liegl, Evan Ball, Margarita Raygada, Angela H. Lai, Lorna Kelly, Jason L. Hornick, Maureen J. O’Sullivan, Ronald R. de Krijger, Winand N.M. Dinjens, George D. Demetri, Cristina R. Antonescu, Jonathan A. Fletcher, Lee J. Helman, Constantine A. Stratakis - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 611

  9. Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis)

    Authors: Shivaani Kummar, Geraldine O’Sullivan Coyne, T. Khanh, Barış Türkbey, Paul S. Meltzer, Eric C. Polley, Peter L. Choyke, Robert Meehan, Rasa Vilimas, Yvonne Horneffer, Lamin Juwara, Ann Lih, Amul Choudhary, Sandra A. Mitchell, Lee J. Helman, James H. Doroshow, Alice P. Chen - Journal of Clinical Oncology 2017 cited by 188

  10. The Childhood Cancer Data Initiative: Using the Power of Data to Learn From and Improve Outcomes for Every Child and Young Adult With Pediatric Cancer

    Authors: Joseph Flores‐Toro, Subhashini Jagu, Gregory T. Armstrong, David F. Arons, Gregory J. Aune, Stephen J. Chanock, Douglas S. Hawkins, Allison P. Heath, Lee J. Helman, Katherine A. Janeway, Jason Levine, Ellyn Miller, Lynne Penberthy, Charles W.M. Roberts, Eve Shalley, Jack F. Shern, Malcolm A. Smith, Louis M. Staudt, Samuel L. Volchenboum, Jinghui Zhang, Jean C. Zenklusen, Douglas R. Lowy, Norman E. Sharpless, Jaime M. Guidry Auvil, Anthony R. Kerlavage, Brigitte C. Widemann, Gregory H. Reaman, Warren A. Kibbe, James H. Doroshow, on behalf of Childhood Cancer Data Initiative Working Groups, Richard Aplenc, Caitlyn W. Barrett, Naomi Bartley, Vicki Buenger, Ethan Cerami, Susan L. Cohn, Susan I. Colace, Carrye Cost, Brian D. Crompton, Tanja M. Davidsen, Sharon J. Diskin, Jamie Ennis Bloyd, Suzanne J. Forrest, Maryam Fouladi, Amar Gajjar, Julia Glade Bender, Nancy Goodman, M. Monica Gramatges, Casey S. Greene, Julie Guillot, Amanda Haddock, Melissa Haendel, D. Ashley Hill, Amie E. Hwang, Daphne Kaas-Hogan, E. Anders Kolb, Andrew L. Kung, Salvatore La Rosa, Theodore W. Laetsch, Elizabeth R. Lawlor, Philip J. Lupo, Troy A. McEachron, Clay McLeod, Shannon K. McWeeney, Jill P. Mesirov, Sarah Milberg, Andy Olshan, Corrie Painter, Donald W. Parsons, Aubrey Reichard-Eline, Karlyne M. Reilly, Adam Resnick, Abby B. Sandler, Nita L. Seibel, Nilay D. Shah, David A. Siegel, Logan G. Spector, E. Alejandro Sweet‐Cordero, Gail E. Tomlinson, Emily S. Tonorezos, James V. Tricoli, Olena M. Vaske, Mary Frances Wedekind, Brent R. Weil, Torunn I. Yock - Journal of Clinical Oncology 2023 cited by 47

  11. Mechanisms of sarcoma development

    Authors: Lee J. Helman, Paul S. Meltzer - Nature reviews. Cancer 2003 cited by 451

  12. Presurgical Chemotherapy Compared With Immediate Surgery and Adjuvant Chemotherapy for Nonmetastatic Osteosarcoma: Pediatric Oncology Group Study POG-8651

    Authors: Allen M. Goorin, Douglas J. Schwartzentruber, Meenakshi Devidas, Mark C. Gebhardt, Alberto G. Ayala, Michael B. Harris, Lee J. Helman, Holcombe E. Grier, Michael P. Link - Journal of Clinical Oncology 2003 cited by 395

  13. Surveillance Recommendations for Children with Overgrowth Syndromes and Predisposition to Wilms Tumors and Hepatoblastoma

    Authors: Jennifer M. Kalish, Leslie Doros, Lee J. Helman, Raoul C. M. Hennekam, Roland P. Kuiper, Saskia M. Maas, Eamonn R. Maher, Kim E. Nichols, Sharon E. Plon, Christopher C. Porter, Surya P. Rednam, Kris Ann P. Schultz, Lisa J. States, Gail E. Tomlinson, Kristin Zelley, Todd E. Druley - Clinical Cancer Research 2017 cited by 201

  14. SARC025 arms 1 and 2: A phase 1 study of the poly(ADP‐ribose) polymerase inhibitor niraparib with temozolomide or irinotecan in patients with advanced Ewing sarcoma

    Authors: Rashmi Chugh, Karla V. Ballman, Lee J. Helman, Shreyaskumar Patel, Jeremy Whelan, Brigitte C. Widemann, Yao Lu, Douglas S. Hawkins, Leo Mascarenhas, John Glod, Jiuping Ji, Yiping Zhang, Denise Reinke, Sandra J. Strauss - Cancer 2020 cited by 46

  15. R1507, a Monoclonal Antibody to the Insulin-Like Growth Factor 1 Receptor, in Patients With Recurrent or Refractory Ewing Sarcoma Family of Tumors: Results of a Phase II Sarcoma Alliance for Research Through Collaboration Study

    Authors: Alberto S. Pappo, Shreyaskumar Patel, John Crowley, Denise K. Reinke, Klaus-Peter Kuenkele, Sant P. Chawla, Guy C. Toner, Robert G. Maki, Paul A. Meyers, Rashmi Chugh, Kristen N. Ganjoo, Scott M. Schuetze, Heribert Juergens, Michael Leahy, Birgit Geoerger, Robert S. Benjamin, Lee J. Helman, Laurence H. Baker - Journal of Clinical Oncology 2011 cited by 321

  16. Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism

    Authors: Xiaolin Wan, B Harkavy, N Shen, Patrick J. Grohar, Lee J. Helman - Oncogene 2006 cited by 747

  17. Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening

    Authors: Patrick J. Grohar, Girma M. Woldemichael, Laurie B. Griffin, Arnulfo Mendoza, Qing-Rong Chen, Choh Yeung, Duane Currier, Sean Davis, Chand Khanna, Javed Khan, James B. McMahon, Lee J. Helman - JNCI Journal of the National Cancer Institute 2011 cited by 204

  18. SARC006: Phase II Trial of Chemotherapy in Sporadic and Neurofibromatosis Type 1 Associated Chemotherapy-Naive Malignant Peripheral Nerve Sheath Tumors

    Authors: Christine S. Higham, Seth M. Steinberg, Eva Dombi, Arie Perry, Lee J. Helman, Scott M. Schuetze, Joseph A. Ludwig, Arthur P. Staddon, Mohammed Milhem, Daniel A. Rushing, Robin L. Jones, Michael B. Livingston, Stewart Goldman, Christopher L. Moertel, Lars M. Wagner, David E. Janhofer, Christina M. Annunziata, Denise K. Reinke, Lauren Long, David Viskochil, Larry Baker, Brigitte C. Widemann - Sarcoma 2017 cited by 97

  19. Dual Targeting of EWS-FLI1 Activity and the Associated DNA Damage Response with Trabectedin and SN38 Synergistically Inhibits Ewing Sarcoma Cell Growth

    Authors: Patrick J. Grohar, Laure E. Segars, Choh Yeung, Yves Pommier, Maurizio D’Incalci, Arnulfo Mendoza, Lee J. Helman - Clinical Cancer Research 2013 cited by 86

  20. LRRC15 antibody‐drug conjugates show promise as osteosarcoma therapeutics in preclinical studies

    Authors: Katherine K. Slemmons, Sanjit Mukherjee, Paul S. Meltzer, James W. Purcell, Lee J. Helman - Pediatric Blood & Cancer 2020 cited by 24

  21. A Phase II Trial of Guadecitabine in Children and Adults with SDH-Deficient GIST, Pheochromocytoma, Paraganglioma, and HLRCC-Associated Renal Cell Carcinoma

    Authors: John A. Ligon, R. Taylor Sundby, Mary Frances Wedekind, Fernanda I. Arnaldez, Jaydira Del Rivero, Lori Wiener, Ramaprasad Srinivasan, Melissa Spencer, Amanda Carbonell, Haiyan Lei, John Shern, Seth M. Steinberg, William D. Figg, Cody J. Peer, Sara Zimmerman, Josquin Moraly, Xia Xu, Stephen Fox, King C. Chan, Michael I. Barbato, Þorkell Andrésson, Naomi Taylor, Karel Pacák, Jonathan Keith Killian, Eva Dombi, W. Marston Linehan, Markku Miettinen, Richard Piekarz, Lee J. Helman, Paul S. Meltzer, Brigitte C. Widemann, John Glod - Clinical Cancer Research 2022 cited by 22

  22. Toward a Drug Development Path That Targets Metastatic Progression in Osteosarcoma

    Authors: Chand Khanna, Timothy M. Fan, Richard Görlick, Lee J. Helman, Eugenie S. Kleinerman, Peter C. Adamson, Peter J. Houghton, William D. Tap, Danny R. Welch, Patricia S. Steeg, Glenn Merlino, Poul H. Sorensen, Paul S. Meltzer, David G. Kirsch, Katherine A. Janeway, Brenda J. Weigel, Lor R. Randall, Stephen J. Withrow, Melissa Paoloni, Rosandra N. Kaplan, Beverly A. Teicher, Nita L. Seibel, Malcolm A. Smith, Aykut Üren, Shreyaskumar Patel, Jeffrey M. Trent, Sharon A. Savage, Lisa Mirabello, Denise K. Reinke, Donald A. Barkaukas, Mark Krailo, Mark L. Bernstein - Clinical Cancer Research 2014 cited by 199

  23. Recurrent epimutation ofSDHCin gastrointestinal stromal tumors

    Authors: Jonathan Keith Killian, Markku Miettinen, Robert L. Walker, Yonghong Wang, Yuelin J. Zhu, Joshua J. Waterfall, Natalia Noyes, Parvathy Retnakumar, Zhiming Yang, William I. Smith, M. Scott Killian, Christopher Lau, Marbin Pineda, Jennifer Walling, Holly Stevenson, Carly Smith, Zengfeng Wang, Jerzy Lasota, Su Young Kim, Sosipatros A. Boikos, Lee J. Helman, Paul S. Meltzer - Science Translational Medicine 2014 cited by 193

  24. A Pilot Study of Consolidative Immunotherapy in Patients with High-Risk Pediatric Sarcomas

    Authors: Crystal L. Mackall, Eunice H. Rhee, Elizabeth J. Read, Hanh Khuu, Susan F. Leitman, Donna Bernstein, Merertu Tesso, Lauren Long, David J. Grindler, Margret Merino, William Kopp, Maria Tsokos, Jay A. Berzofsky, Lee J. Helman - Clinical Cancer Research 2008 cited by 158