Mark B. Pepys
Active 1975–2025
- 128
- Papers
- 44,486
- Citations
- 97
- h-index
- 127
- i10-index
Citations
Citation sources
Countries
Institutions
- University College London1.2%
- Harvard University1.2%
- Brigham and Women's Hospital1%
- University of Cambridge0.7%
- Inserm0.6%
- The Royal Free Hospital0.5%
- Other94.8%
Fields
- Medicine54.2%
- Biochemistry, Genetics and Molecular Biology26%
- Immunology and Microbiology8.1%
- Neuroscience3%
- Materials Science1.4%
- Nursing1%
- Other6.3%
Topics
- Adipokines, Inflammation, and Metabolic Diseases6.3%
- Amyloidosis: Diagnosis, Treatment, Outcomes4.2%
- Alzheimer's disease research and treatments4.2%
- Inflammatory Biomarkers in Disease Prognosis2.2%
- Protein Structure and Dynamics2.2%
- Atherosclerosis and Cardiovascular Diseases1.9%
- Other79%
Coauthors
- Philip N. Hawkins44
- J. Ruth Gallimore21
- Julian D. Gillmore20
- Glenys A. Tennent17
- P. Patrizia Mangione13
- Vittorio Bellotti12
- Graham W. Taylor10
- M L Baltz9
- Winston L. Hutchinson9
- David R. Booth8
- W. L. Hutchinson8
- Frederick C. de Beer7
- Gideon M. Hirschfield7
- Sofia Giorgetti7
- Guglielmo Verona6
- Alessandra Corazza5
- Caroline Sabin5
- Diana Canetti5
- Helen J. Lachmann5
- Melvyn Kahan5
- Monica Stoppini5
- Riccardo Porcari5
- Sara Raimondi5
- Steve Wood5
All papers
- C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis
Authors: Stephen Kaptoge, Stephen Kaptoge, Emanuele Di Angelantonio, Gordon Lowe, Mark B. Pepys, Simon G. Thompson, Rory Collins - The Lancet 2009 cited by 2,503
- C-reactive protein: a critical update
Authors: Mark B. Pepys, Gideon M. Hirschfield - Journal of Clinical Investigation 2003 cited by 3,513
- C-Reactive Protein and Other Circulating Markers of Inflammation in the Prediction of Coronary Heart Disease
Authors: John Danesh, Jeremy G. Wheeler, Gideon M. Hirschfield, Shinichi Eda, Guðný Eiríksdóttir, Ann Rumley, Gordon Lowe, Mark B. Pepys, Vilmundur Guðnason - New England Journal of Medicine 2004 cited by 2,954
- Common core structure of amyloid fibrils by synchrotron X-ray diffraction 1 1Edited by F. E. Cohen
Authors: Margaret Sunde, Louise C. Serpell, Mark Bartlam, Paul E. Fraser, Mark B. Pepys, Colin Blake - Journal of Molecular Biology 1997 cited by 1,706
- The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable Angina
Authors: Giovanna Liuzzo, Luigi M. Biasucci, J. Ruth Gallimore, Rita L. Grillo, Antonio G. Rebuzzi, Mark B. Pepys, Attilio Maseri - New England Journal of Medicine 1994 cited by 2,353
- The physiological structure of human C-reactive protein and its complex with phosphocholine
Authors: Darren A. Thompson, Mark B. Pepys, Steve Wood - Structure 1999 cited by 827
- Targeting C-reactive protein for the treatment of cardiovascular disease
Authors: Mark B. Pepys, Gideon M. Hirschfield, Glenys A. Tennent, J. Ruth Gallimore, Melvyn Kahan, Vittorio Bellotti, Philip N. Hawkins, R. M. Myers, Martin D. Smith, Alessandra Polara, Alexander J. A. Cobb, Steven V. Ley, J. Andrew Aquilina, Carol V. Robinson, Isam Sharif, Gillian A. Gray, Caroline Sabin, Michelle C. Jenvey, Simon Kolstoe, Darren A. Thompson, Stephen P. Wood - Nature 2006 cited by 676
- A novel mechano‐enzymatic cleavage mechanism underlies transthyretin amyloidogenesis
Authors: Julien Marcoux, P. Patrizia Mangione, Riccardo Porcari, Matteo T. Degiacomi, Guglielmo Verona, Graham W. Taylor, Sofia Giorgetti, Sara Raimondi, Sarah Cianférani, Justin L. P. Benesch, Ciro Cecconi, Mohsin M. Naqvi, Julian D. Gillmore, Philip N. Hawkins, Monica Stoppini, Carol V. Robinson, Mark B. Pepys, Vittorio Bellotti - EMBO Molecular Medicine 2015 cited by 164
- Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component
Authors: Duncan Richards, Louise Cookson, Aliénor Berges, Sharon V. Barton, Thirusha Lane, James M. Ritter, Marianna Fontana, James Moon, Massimo Pinzani, Julian D. Gillmore, Philip N. Hawkins, Mark B. Pepys - New England Journal of Medicine 2015 cited by 376
- Repeat doses of antibody to serum amyloid P component clear amyloid deposits in patients with systemic amyloidosis
Authors: Duncan Richards, Louise Cookson, Sharon V. Barton, Lia Liefaard, Thirusha Lane, David F. Hutt, James M. Ritter, Marianna Fontana, James Moon, Julian D. Gillmore, Ashutosh Wechalekar, Philip N. Hawkins, Mark B. Pepys - Science Translational Medicine 2018 cited by 137
- C-Reactive Protein, a Sensitive Marker of Inflammation, Predicts Future Risk of Coronary Heart Disease in Initially Healthy Middle-Aged Men
Authors: Wolfgang Köenig, M. Sund, Margit Fröhlich, Hans-Günther Fischer, Hannelore Löwel, Angela Döring, Winston L. Hutchinson, Mark B. Pepys - Circulation 1999 cited by 1,947
- Three dimensional structure of human C-reactive protein
Authors: A.K. Shrive, Graham M.T. Gheetham, David W. Holden, Dean A. A. Myles, William G. Turnell, John E. Volanakis, Mark B. Pepys, Anne C. Bloomer, Trevor J. Greenhough - Nature Structural & Molecular Biology 1996 cited by 364
- Serum levels of C‐reactive protein in Crohn's disease and ulcerative colitis
Authors: Evelyn Fagan, Roland Dyck, Paul N. Maton, H. J. F. Hodgson, V. S. Chadwick, Aviva Petrie, Mark B. Pepys - European Journal of Clinical Investigation 1982 cited by 313
- Plasminogen activation triggers transthyretin amyloidogenesis in vitro
Authors: P. Patrizia Mangione, Guglielmo Verona, Alessandra Corazza, Julien Marcoux, Diana Canetti, Sofia Giorgetti, Sara Raimondi, Monica Stoppini, Marilena Esposito, Annalisa Relini, Claudio Canale, Maurizia Valli, Loredana Marchese, Giulia Faravelli, Laura Obici, Philip N. Hawkins, Graham W. Taylor, Julian D. Gillmore, Mark B. Pepys, Vittorio Bellotti - Journal of Biological Chemistry 2018 cited by 106
- Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis
Authors: David R. Booth, Margaret Sunde, Vittorio Bellotti, Carol V. Robinson, Winston L. Hutchinson, Paul E. Fraser, Philip N. Hawkins, Christopher M. Dobson, Sheena E. Radford, Colin Blake, Mark B. Pepys - Nature 1997 cited by 1,048
- Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease.
Authors: David M. Vigushin, Mark B. Pepys, Philip N. Hawkins - Journal of Clinical Investigation 1993 cited by 642
- Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid A protein
Authors: Julian D. Gillmore, Laurence Lovat, M.R. Persey, Mark B. Pepys, Philip N. Hawkins - The Lancet 2001 cited by 601
- Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis
Authors: P. Patrizia Mangione, Riccardo Porcari, Julian D. Gillmore, Piero Pucci, Maria Monti, Mattia Porcari, Sofia Giorgetti, Loredana Marchese, Sara Raimondi, Louise C. Serpell, Wenjie Chen, Annalisa Relini, Julien Marcoux, Innes Clatworthy, Graham W. Taylor, Glenys A. Tennent, Carol V. Robinson, Philip N. Hawkins, Monica Stoppini, Stephen P. Wood, Mark B. Pepys, Vittorio Bellotti - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 125
- Amyloidosis
Authors: Mark B. Pepys - Annual Review of Medicine 2005 cited by 553
- Low‐level increases in serum C‐reactive protein are present in early osteoarthritis of the knee and predict progressive disease
Authors: Tim D. Spector, Deborah Hart, D. Nandra, David Doyle, N. Mackillop, J. Ruth Gallimore, Mark B. Pepys - Arthritis & Rheumatism 1997 cited by 402
- Solid phase radioimmunoassays for human C-reactive protein
Authors: Brian Shine, Frits C. de Beer, Mark B. Pepys - Clinica Chimica Acta 1981 cited by 319
- Human plasma fibrinogen is synthesized in the liver
Authors: Glenys A. Tennent, Stephen O. Brennan, Arie J. Stangou, John O’Grady, Philip N. Hawkins, Mark B. Pepys - Blood 2006 cited by 315
- Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis
Authors: Ivana Slámová, Rozita Adib, Stéphan Ellmerich, Michal R. Golos, Janet A. Gilbertson, Nicola Botcher, Diana Canetti, Graham W. Taylor, Nigel B. Rendell, Glenys A. Tennent, Guglielmo Verona, Riccardo Porcari, P. Patrizia Mangione, Julian D. Gillmore, Mark B. Pepys, Vittorio Bellotti, Philip N. Hawkins, Raya Al‐Shawi, J. Paul Simons - Nature Communications 2021 cited by 37
- Human lysozyme gene mutations cause hereditary systemic amyloidosis
Authors: Mark B. Pepys, Philip N. Hawkins, David R. Booth, David M. Vigushin, GA Tennent, Anne K. Soutar, Nicholas F. Totty, Ong Nam Phuong Nguyen, C. C. F. Blake, C. J. Terry, Terry Feest, A. M. Zalin, J. Justin Hsuan - Nature 1993 cited by 662
