Michael B. Sporn
Active 1961–2022
- 278
- Papers
- 89,134
- Citations
- 156
- h-index
- 278
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology42%
- Medicine40.9%
- Immunology and Microbiology7.8%
- Neuroscience3.5%
- Engineering1.1%
- Agricultural and Biological Sciences0.9%
- Other3.8%
Topics
- TGF-β signaling in diseases4.7%
- Genomics, phytochemicals, and oxidative stress2.7%
- Cell Adhesion Molecules Research1.9%
- Retinoids in leukemia and cellular processes1.6%
- Wound Healing and Treatments1.3%
- Antioxidant Activity and Oxidative Stress1.3%
- Other86.5%
Coauthors
- Anita B. Roberts110
- Karen T. Liby33
- Gordon W. Gribble25
- Tadashi Honda24
- Kathleen C. Flanders23
- Lalage M. Wakefield22
- Nanjoo Suh22
- Joseph M. Smith20
- Charlotte R. Williams19
- David Danielpour14
- N S Roche14
- S J Kim14
- Andrew G. Geiser12
- Mario A. Anzano12
- Renee Risingsong12
- Thomas W. Kensler12
- Adam B. Glick9
- Darlene B. Royce9
- Masayuki Yamamoto9
- Sonia B. Jakowlew9
- Charles A. Frolik8
- Dianne L. Newton8
- Mark M. Yore8
- Paturu Kondaiah8
All papers
- NRF2 and cancer: the good, the bad and the importance of context
Authors: Michael B. Sporn, Karen T. Liby - Nature reviews. Cancer 2012 cited by 1,052
- Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.
Authors: A B Kulkarni, C G Huh, Daniel M. Becker, Andrew G. Geiser, M Lyght, Kathleen C. Flanders, Alistair B. Roberts, Michael B. Sporn, Jerrold M. Ward, Stefan Karlsson - National Academy of Sciences, Proceedings of the National Academy of Sciences 1993 cited by 1,952
- Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress
Authors: Albena T. Dinkova‐Kostova, Karen T. Liby, Katherine K. Stephenson, W. David Holtzclaw, Xiangqun Gao, Nanjoo Suh, Charlotte R. Williams, Renee Risingsong, Tadashi Honda, Gordon W. Gribble, Michael B. Sporn, Paul Talalay - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 cited by 566
- Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice
Authors: Tangying Lu, Rupal Ramakrishnan, Soner Altiok, Je In Youn, Pingyan Cheng, Esteban Celis, В. М. Писарев, Simon Sherman, Michael B. Sporn, Dmitry I. Gabrilovich - Journal of Clinical Investigation 2011 cited by 361
- Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.
Authors: Anita B. Roberts, Michael B. Sporn, Richard K. Assoian, Joseph M. Smith, N S Roche, Lalage M. Wakefield, Ursula Heine, L A Liotta, Vincent Falanga, John H. Kehrl - National Academy of Sciences, Proceedings of the National Academy of Sciences 1986 cited by 2,880
- Synthetic Oleanane Triterpenoids: Multifunctional Drugs with a Broad Range of Applications for Prevention and Treatment of Chronic Disease
Authors: Karen T. Liby, Michael B. Sporn - Pharmacological Reviews 2012 cited by 406
- The tumour microenvironment as a target for chemoprevention
Authors: Adriana Albini, Michael B. Sporn - Nature reviews. Cancer 2007 cited by 820
- Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.
Authors: Richard K. Assoian, Akira Komoriya, Chester A. Meyers, Dorothea M. Miller, Michael B. Sporn - Journal of Biological Chemistry 1983 cited by 1,602
- New Synthetic Triterpenoids: Potent Agents for Prevention and Treatment of Tissue Injury Caused by Inflammatory and Oxidative Stress
Authors: Michael B. Sporn, Karen T. Liby, Mark M. Yore, Liangfeng Fu, Justin M. Lopchuk, Gordon W. Gribble - Journal of Natural Products 2011 cited by 313
- Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer
Authors: Karen T. Liby, Mark M. Yore, Michael B. Sporn - Nature reviews. Cancer 2007 cited by 637
- Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis
Authors: Arie Neymotin, Noel Y. Calingasan, Elizabeth Wille, Nima Naseri, Susanne Petri, Maria Damiano, Karen T. Liby, Renee Risingsong, Michael B. Sporn, M. Flint Beal, Mahmoud Kiaei - Free Radical Biology and Medicine 2011 cited by 215
- Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington's disease
Authors: Cliona Stack, Daniel Ho, Elizabeth Wille, Noel Y. Calingasan, Charlotte R. Williams, Karen T. Liby, Michael B. Sporn, Magali Dumont, M. Flint Beal - Free Radical Biology and Medicine 2010 cited by 172
- Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.
Authors: Sharon M. Wahl, D A Hunt, Lalage M. Wakefield, Nancy McCartney‐Francis, L M Wahl, Anita B. Roberts, Michael B. Sporn - National Academy of Sciences, Proceedings of the National Academy of Sciences 1987 cited by 1,281
- Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide
Authors: Rajesh K. Thimmulappa, Catherine Scollick, Kassim Traore, Melinda S. Yates, Michael A. Trush, Karen T. Liby, Michael B. Sporn, Masayuki Yamamoto, Thomas W. Kensler, Shyam Biswal - Biochemical and Biophysical Research Communications 2006 cited by 351
- Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes
Authors: Melinda S. Yates, Masafumi Tauchi, Fumiki Katsuoka, Kathleen C. Flanders, Karen T. Liby, Tadashi Honda, Gordon W. Gribble, Delinda A. Johnson, Jeffrey A. Johnson, Neal C. Burton, Tomás R. Guilarte, Masayuki Yamamoto, Michael B. Sporn, Thomas W. Kensler - Molecular Cancer Therapeutics 2007 cited by 293
- Anti-inflammatory Triterpenoid Blocks Immune Suppressive Function of MDSCs and Improves Immune Response in Cancer
Authors: Srinivas Nagaraj, Je-In Youn, Hannah Weber, Cristina Iclozan, Lily Lu, Matthew J. Cotter, Colin J. Meyer, Carlos Becerra, Mayer Fishman, Scott Antonia, Michael B. Sporn, Karen T. Liby, Bhupendra Rawal, Ji‐Hyun Lee, Dmitry I. Gabrilovich - Clinical Cancer Research 2010 cited by 276
- New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.
Authors: Anita B. Roberts, Mario A. Anzano, Lois C. Lamb, Joseph M. Smith, Michael B. Sporn - National Academy of Sciences, Proceedings of the National Academy of Sciences 1981 cited by 915
- Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice
Authors: Thomas E. Sussan, Tirumalai Rangasamy, David J. Blake, Deepti Malhotra, Hazim El‐Haddad, Djahida Bedja, Melinda S. Yates, Ponvijay Kombairaju, Masayuki Yamamoto, Karen T. Liby, Michael B. Sporn, Kathleen L. Gabrielson, Hunter C. Champion, Rubin M. Tuder, Thomas W. Kensler, Shyam Biswal - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 346
- Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice
Authors: Melinda S. Yates, Quynh T. Tran, Patrick M. Dolan, William O. Osburn, Soona Shin, Colin McCulloch, Jay B. Silkworth, Keiko Taguchi, Masayuki Yamamoto, Charlotte R. Williams, Karen T. Liby, Michael B. Sporn, Thomas R. Sutter, Thomas W. Kensler - Carcinogenesis 2009 cited by 266
- Design and synthesis of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, a novel and highly active inhibitor of nitric oxide production in mouse macrophages
Authors: Tadashi Honda, BarbieAnn V. Rounds, Gordon W. Gribble, Nanjoo Suh, Yongping Wang, Michael B. Sporn - Bioorganic & Medicinal Chemistry Letters 1998 cited by 204
- Recombinant latent transforming growth factor beta 1 has a longer plasma half-life in rats than active transforming growth factor beta 1, and a different tissue distribution.
Authors: Lalage M. Wakefield, Thomas S. Winokur, Robin S. Hollands, Kent W. Christopherson, Arthur D. Levinson, Michael B. Sporn - Journal of Clinical Investigation 1990 cited by 317
- The Synthetic Triterpenoids, CDDO and CDDO-Imidazolide, Are Potent Inducers of Heme Oxygenase-1 and Nrf2/ARE Signaling
Authors: Karen T. Liby, Thomas Hock, Mark M. Yore, Nanjoo Suh, Andrew E. Place, Renee Risingsong, Charlotte R. Williams, Darlene B. Royce, Tadashi Honda, Yukiko Honda, Gordon W. Gribble, Nathalie Hill‐Kapturczak, Anupam Agarwal, Michael B. Sporn - Cancer Research 2005 cited by 284
- Distinct Regulations of HO-1 Gene Expression for Stress Response and Substrate Induction
Authors: Anqi Zhang, Takafumi Suzuki, Saki Adachi, Eriko Naganuma, Norio Suzuki, Tomonori Hosoya, Ken Itoh, Michael B. Sporn, Masayuki Yamamoto - Molecular and Cellular Biology 2021 cited by 31
- Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.
Authors: John H. Kehrl, Lalage M. Wakefield, Anita B. Roberts, Sonia B. Jakowlew, M Alvarez-Mon, Rik Derynck, Michael B. Sporn, Anthony S. Fauci - The Journal of Experimental Medicine 1986 cited by 1,591
