Michael C. Heinrich
Active 1997–2025
- 167
- Papers
- 47,228
- Citations
- 102
- h-index
- 163
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine70.8%
- Biochemistry, Genetics and Molecular Biology21.2%
- Immunology and Microbiology3.8%
- Computer Science1%
- Chemistry0.7%
- Neuroscience0.7%
- Other1.8%
Topics
- Gastrointestinal Tumor Research and Treatment6.4%
- Chronic Myeloid Leukemia Treatments5.9%
- Sarcoma Diagnosis and Treatment4.2%
- Chronic Lymphocytic Leukemia Research2.9%
- Acute Myeloid Leukemia Research2.7%
- Gastrointestinal disorders and treatments2.5%
- Other75.4%
Coauthors
- Christopher L. Corless62
- Jonathan A. Fletcher40
- Margaret von Mehren36
- George D. Demetri33
- Suzanne George32
- Sebastian Bauer26
- Brian Druker21
- Robin L. Jones19
- César Serrano18
- Patrick Schöffski18
- Christopher D.�M. Fletcher17
- Jonathan C. Trent15
- Michael W. Deininger15
- Jean‐Yves Blay14
- Rodrigo Ruiz‐Soto14
- Hans Gelderblom13
- Ajia Town12
- Brian P. Rubin12
- Charles D. Blanke12
- Annick D. Van den Abbeele11
- John Zalcberg11
- Diana Griffith10
- Laura McGreevey10
- Yoon‐Koo Kang10
All papers
- Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure
Authors: Timothy P. Hughes, Michael J. Mauro, Jörge E. Cortes, Hironobu Minami, Delphine Réa, Daniel J. DeAngelo, Massimo Breccia, Yeow-Tee Goh, Moshe Talpaz, Andreas Hochhaus, Philipp le Coutre, Oliver G. Ottmann, Michael C. Heinrich, Juan Luis Steegmann, Michael W. Deininger, Jeroen J. W. M. Janssen, François-Xavier Mahon, Yosuke Minami, David T Yeung, David M. Ross, Martin S. Tallman, Jae H. Park, Brian Druker, David Hynds, Yuyan Duan, Christophe Meille, Florence Hourcade‐Potelleret, K. Gary J. Vanasse, Fabian Lang, Dong‐Wook Kim - New England Journal of Medicine 2019 cited by 467
- Efficacy and Safety of Imatinib Mesylate in Advanced Gastrointestinal Stromal Tumors
Authors: George D. Demetri, Margaret von Mehren, Charles D. Blanke, Annick D. Van den Abbeele, Burton Eisenberg, Peter Roberts, Michael C. Heinrich, David A. Tuveson, Samuel Singer, Milos J. Janicek, Jonathan A. Fletcher, Stuart G. Silverman, Sandra Silberman, Renaud Capdeville, Beate Kiese, Bin Peng, Saša Dimitrijević, Brian Druker, Christopher L. Corless, Christopher D.�M. Fletcher, Heikki Joensuu - New England Journal of Medicine 2002 cited by 4,389
- Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial
Authors: George D. Demetri, Allan T. van Oosterom, Christopher R. Garrett, Martin E. Blackstein, Manisha H. Shah, Jaap Verweij, Grant A. McArthur, Ian Judson, Michael C. Heinrich, Jeffrey A. Morgan, Jayesh Desai, Christopher D.�M. Fletcher, Suzanne George, Carlo L. Bello, Xin Huang, Charles M. Baum, Paolo G. Casali - The Lancet 2006 cited by 2,595
- Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy against Highly Resistant BCR-ABL1 Mutants
Authors: Christopher A. Eide, Matthew S. Zabriskie, Samantha L. Savage, Orlando Antelope, Nadeem A. Vellore, Hein Than, Anna Reister Schultz, Phillip M. Clair, Amber D. Bowler, Anthony D. Pomicter, Dongqing Yan, Anna V. Senina, Qiang Wang, Todd W. Kelley, Philippe Szankasi, Michael C. Heinrich, Jeffrey Tyner, Delphine Réa, Jean-Michel Cayuela, Dong‐Wook Kim, Cristina E. Tognon, Thomas O’Hare, Brian Druker, Michael W. Deininger - Cancer Cell 2019 cited by 245
- PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors
Authors: Michael C. Heinrich, Christopher L. Corless, Anette Duensing, Laura McGreevey, Chang-Jie Chen, Nora Joseph, Samuel Singer, Diana Griffith, Andrea Haley, Ajia Town, George D. Demetri, Christopher D.�M. Fletcher, Jonathan A. Fletcher - Science 2003 cited by 2,302
- Avapritinib in advanced PDGFRA D842V-mutant gastrointestinal stromal tumour (NAVIGATOR): a multicentre, open-label, phase 1 trial
Authors: Michael C. Heinrich, Robin L. Jones, Margaret von Mehren, Patrick Schöffski, César Serrano, Yoon‐Koo Kang, Philippe A. Cassier, Olivier Mir, Ferry A.L.M. Eskens, William D. Tap, Piotr Rutkowski, Sant P. Chawla, Jonathan C. Trent, Meera Tugnait, Erica N Evans, Tamieka Lauz, Teresa Zhou, Maria Roche, Beni B. Wolf, Sebastian Bauer, Suzanne George - The Lancet Oncology 2020 cited by 304
- Ripretinib in patients with advanced gastrointestinal stromal tumours (INVICTUS): a double-blind, randomised, placebo-controlled, phase 3 trial
Authors: Jean‐Yves Blay, César Serrano, Michael C. Heinrich, John Zalcberg, Sebastian Bauer, Hans Gelderblom, Patrick Schöffski, Robin L. Jones, Steven Attia, Gina Z. D’Amato, Ping Chi, Peter Reichardt, Julie Meade, Kelvin Shi, Rodrigo Ruiz‐Soto, Suzanne George, Margaret von Mehren - The Lancet Oncology 2020 cited by 407
- Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants
Authors: Bryan D. Smith, Michael D. Kaufman, Wei-Ping Lu, Anu Gupta, Cynthia B. Leary, Scott Wise, Thomas J. Rutkoski, Yu Mi Ahn, Gada Al-Ani, Stacie L. Bulfer, Timothy M. Caldwell, Lawrence Chun, Carol L. Ensinger, Molly M. Hood, Arin McKinley, William C. Patt, Rodrigo Ruiz‐Soto, Ying Su, Hanumaiah Telikepalli, Ajia Town, Benjamin A. Turner, Lakshminarayana Vogeti, Subha Vogeti, Karen Yates, Filip Jankú, Albiruni Ryan Abdul Razak, Oliver Rosen, Michael C. Heinrich, Daniel L. Flynn - Cancer Cell 2019 cited by 277
- Imatinib for Melanomas Harboring Mutationally Activated or Amplified KIT Arising on Mucosal, Acral, and Chronically Sun-Damaged Skin
Authors: F. Stephen Hodi, Christopher L. Corless, Anita Giobbie‐Hurder, Jonathan A. Fletcher, Mei‐Jun Zhu, Adrián Mariño‐Enríquez, Philip Friedlander, René González, Jeffrey S. Weber, Thomas F. Gajewski, Steven O’Day, Kevin B. Kim, Donald P. Lawrence, Keith T. Flaherty, Jason J. Luke, Frances A. Collichio, Marc S. Ernstoff, Michael C. Heinrich, Carol Beadling, Katherine Zukotynski, Jeffrey T. Yap, Annick D. Van den Abbeele, George D. Demetri, David E. Fisher - Journal of Clinical Oncology 2013 cited by 595
- Kinase Mutations and Imatinib Response in Patients With Metastatic Gastrointestinal Stromal Tumor
Authors: Michael C. Heinrich, Christopher L. Corless, George D. Demetri, Charles D. Blanke, Margaret von Mehren, Heikki Joensuu, Laura McGreevey, Changjie Chen, Annick D. Van den Abbeele, Brian Druker, Beate Kiese, Burton Eisenberg, Peter Roberts, Samuel Singer, Christopher D.�M. Fletcher, Sandra Silberman, Saša Dimitrijević, Jonathan A. Fletcher - Journal of Clinical Oncology 2003 cited by 2,297
- Gastrointestinal stromal tumours: origin and molecular oncology
Authors: Christopher L. Corless, Christine M. Barnett, Michael C. Heinrich - Nature reviews. Cancer 2011 cited by 887
- New treatment strategies for advanced-stage gastrointestinal stromal tumours
Authors: Lillian R. Klug, Homma M. Khosroyani, Jason D. Kent, Michael C. Heinrich - Nature Reviews Clinical Oncology 2022 cited by 130
- Ripretinib Versus Sunitinib in Patients With Advanced Gastrointestinal Stromal Tumor After Treatment With Imatinib (INTRIGUE): A Randomized, Open-Label, Phase III Trial
Authors: Sebastian Bauer, Robin L. Jones, Jean‐Yves Blay, Hans Gelderblom, Suzanne George, Patrick Schöffski, Margaret von Mehren, John Zalcberg, Yoon‐Koo Kang, Albiruni Abdul Razak, Jonathan C. Trent, Steven Attia, Axel Le Cesne, Ying Su, Julie Meade, Tao Wang, Matthew L. Sherman, Rodrigo Ruiz‐Soto, Michael C. Heinrich - Journal of Clinical Oncology 2022 cited by 111
- Asciminib monotherapy in patients with CML-CP without BCR::ABL1 T315I mutations treated with at least two prior TKIs: 4-year phase 1 safety and efficacy results
Authors: Michael J. Mauro, Timothy P. Hughes, Dong‐Wook Kim, Delphine Réa, Jörge E. Cortes, Andreas Hochhaus, Koji Sasaki, Massimo Breccia, Moshe Talpaz, Oliver G. Ottmann, Hironobu Minami, Yeow Tee Goh, Daniel J. DeAngelo, Michael C. Heinrich, Valle Gómez-Garcı́a de Soria, Philipp le Coutre, François‐Xavier Mahon, Jeroen J. W. M. Janssen, Michael W. Deininger, Naranie Shanmuganathan, Mark B. Geyer, Silvia Cacciatore, Fotis Polydoros, Nithya Agrawal, Matthias Hoch, Fabian Lang - Leukemia 2023 cited by 47
- Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours
Authors: César Serrano, Adrián Mariño‐Enríquez, Derrick L. Tao, Julia Ketzer, Grant Eilers, Mei‐Jun Zhu, Channing Yu, Aristotle M. Mannan, Brian P. Rubin, George D. Demetri, Chandrajit P. Raut, Ajia Presnell, Arin McKinley, Michael C. Heinrich, Jeffrey T. Czaplinski, Ewa Sicińska, Sebastian Bauer, Suzanne George, Jonathan A. Fletcher - British Journal of Cancer 2019 cited by 166
- PDGFRA Mutations in Gastrointestinal Stromal Tumors: Frequency, Spectrum and In Vitro Sensitivity to Imatinib
Authors: Christopher L. Corless, Arin Schroeder, Diana Griffith, Ajia Town, Laura McGreevey, Patina M. Harrell, Sharon Shiraga, Troy Bainbridge, Jason R. Morich, Michael C. Heinrich - Journal of Clinical Oncology 2005 cited by 838
- The contemporary management of cancers of the sinonasal tract in adults
Authors: Rajat Thawani, Myung Sun Kim, Asad Arastu, Zizhen Feng, Malinda West, Nicholas Taflin, Kyaw Zin Thein, Ryan Li, Mathew Geltzeiler, Nancy Y. Lee, Clifton D. Fuller, Jennifer R. Grandis, Charalampos S. Floudas, Michael C. Heinrich, Ehab Hanna, Ravi A. Chandra - CA A Cancer Journal for Clinicians 2022 cited by 118
- Heterogeneity of kinase inhibitor resistance mechanisms in GIST
Authors: Bernadette Liegl, Ilana Kepten, Claudia Le, Mei‐Jun Zhu, George D. Demetri, Michael C. Heinrich, CDM Fletcher, Christopher L. Corless, JA Fletcher - The Journal of Pathology 2008 cited by 455
- FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors
Authors: Eileen Shi, Juliann Chmielecki, Chih‐Min Tang, Kai Wang, Michael C. Heinrich, Guhyun Kang, Christopher L. Corless, David S. Hong, Katherine E. Fero, James D. Murphy, Paul T. Fanta, Siraj M. Ali, Martina De Siena, Adam M. Burgoyne, Sujana Movva, Lisa Madlensky, Gregory M. Heestand, Jonathan C. Trent, Razelle Kurzrock, Deborah Morosini, Jeffrey S. Ross, Olivier Harismendy, Jason K. Sicklick - Journal of Translational Medicine 2016 cited by 233
- Cancer-associated fibroblast secretion of PDGFC promotes gastrointestinal stromal tumor growth and metastasis
Authors: Hyunho Yoon, Chih-Min Tang, Sudeep Banerjee, Mayra Yebra, Sangkyu Noh, Adam M. Burgoyne, Jorge de la Torre, Martina De Siena, Mengyuan Liu, Lillian R. Klug, Yoon Young Choi, Mojgan Hosseini, Antonio L. Delgado, Zhiyong Wang, Randall P. French, Andrew M. Lowy, Ronald P. DeMatteo, Michael C. Heinrich, Alfredo Molinolo, J. Silvio Gutkind, Olivier Harismendy, Jason K. Sicklick - Oncogene 2021 cited by 54
- Gastrointestinal stromal tumour
Authors: Brian P. Rubin, Michael C. Heinrich, Christopher L. Corless - The Lancet 2007 cited by 1,043
- In vitro Activity of Bcr-Abl Inhibitors AMN107 and BMS-354825 against Clinically Relevant Imatinib-Resistant Abl Kinase Domain Mutants
Authors: Thomas O’Hare, Denise K. Walters, Eric P. Stoffregen, Taiping Jia, Paul W. Manley, Jürgen Mestan, Sandra W. Cowan‐Jacob, Francis Y. Lee, Michael C. Heinrich, Michael W. Deininger, Brian Druker - Cancer Research 2005 cited by 1,034
- KIT Gene Mutations and Copy Number in Melanoma Subtypes
Authors: Carol Beadling, Erick Jacobson‐Dunlop, F. Stephen Hodi, Claudia Le, Andrea Warrick, Janice Patterson, Ajia Town, Amy Harlow, Frank Cruz, Sharl Azar, Brian P. Rubin, Susan Müller, Robert B. West, Michael C. Heinrich, Christopher L. Corless - Clinical Cancer Research 2008 cited by 636
- Avapritinib Versus Regorafenib in Locally Advanced Unresectable or Metastatic GI Stromal Tumor: A Randomized, Open-Label Phase III Study
Authors: Yoon‐Koo Kang, Suzanne George, Robin L. Jones, Piotr Rutkowski, Lin Shen, Olivier Mir, Shreyaskumar Patel, Yongjian Zhou, Margaret von Mehren, Peter Hohenberger, Víctor M. Villalobos, Mehdi Brahmi, William D. Tap, Jonathan C. Trent, Maria A. Pantaleo, Patrick Schöffski, Kevin He, Paggy Hew, Kate J. Newberry, Maria Roche, Michael C. Heinrich, Sebastian Bauer - Journal of Clinical Oncology 2021 cited by 116
