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Pak H. Chan

Active 1978–2017

143
Papers
33,599
Citations
105
h-index
143
i10-index

Citations

Citations per year for Pak H. Chan1975: 2 citations1980: 2 citations1981: 7 citations1982: 9 citations1983: 19 citations1984: 15 citations1985: 35 citations1986: 9 citations1987: 28 citations1988: 40 citations1989: 43 citations1990: 39 citations1991: 40 citations1992: 53 citations1993: 58 citations1994: 104 citations1995: 100 citations1996: 122 citations1997: 182 citations1998: 223 citations1999: 313 citations2000: 317 citations2001: 407 citations2002: 426 citations2003: 463 citations2004: 543 citations2005: 497 citations2006: 513 citations2007: 449 citations2008: 439 citations2009: 446 citations2010: 403 citations2011: 371 citations2012: 430 citations2013: 347 citations2014: 307 citations2015: 264 citations2016: 208 citations2017: 222 citations2018: 207 citations2019: 594 citations2020: 626 citations2021: 521 citations2022: 432 citations2023: 260 citations2024: 377 citations2025: 163 citations2026: 4 citations1976–1979: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,811 citing papers, 35.3% of this breakdownChina: 1,483 citing papers, 13.8% of this breakdownGermany: 498 citing papers, 4.6% of this breakdownUnited Kingdom: 478 citing papers, 4.4% of this breakdownJapan: 476 citing papers, 4.4% of this breakdownCanada: 328 citing papers, 3% of this breakdownItaly: 318 citing papers, 3% of this breakdownSouth Korea: 296 citing papers, 2.7% of this breakdownIndia: 237 citing papers, 2.2% of this breakdownFrance: 235 citing papers, 2.2% of this breakdownSpain: 201 citing papers, 1.9% of this breakdownSweden: 174 citing papers, 1.6% of this breakdown
0%35.3%Other 20.9%

Institutions

Fields

  • Medicine37.7%
  • Biochemistry, Genetics and Molecular Biology31.1%
  • Neuroscience24.1%
  • Immunology and Microbiology1.7%
  • Nursing1.6%
  • Agricultural and Biological Sciences0.8%
  • Other3%

Topics

  • Neuroinflammation and Neurodegeneration Mechanisms7.1%
  • Mitochondrial Function and Pathology4%
  • Neuroscience and Neuropharmacology Research3.4%
  • Neurological Disease Mechanisms and Treatments2.7%
  • Traumatic Brain Injury and Neurovascular Disturbances2.5%
  • Barrier Structure and Function Studies2%
  • Other78.3%

Coauthors

All papers

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  1. Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke

    Authors: Geoffrey T. Manley, Miki Fujimura, Tonghui Ma, Nobuo Noshita, Ferda Filiz, Andrew W. Bollen, Pak H. Chan, A.S. Verkman - Nature Medicine 2000 cited by 1,502

  2. Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

    Authors: Hailan Chen, Hideyuki Yoshioka, Gab Seok Kim, Joo Eun Jung, Nobuya Okami, Hiroyuki Sakata, Carolina M. Maier, Purnima Narasimhan, Christina E. Goeders, Pak H. Chan - Antioxidants and Redox Signaling 2010 cited by 773

  3. Gpr124 is essential for blood–brain barrier integrity in central nervous system disease

    Authors: Junlei Chang, Michael R. Mancuso, Carolina M. Maier, Xibin Liang, Kanako Yuki, Lu Yang, Jeffrey W. Kwong, Jing Wang, Varsha Rao, Mario Vallon, Cynthia Kosinski, JJ H. Zhang, Amanda T. Mah, Lijun Xu, Le Li, Sharareh Gholamin, Teresa F Reyes, Rui Li, Frank Kuhnert, Xiaoyuan Han, Jenny Yuan, Shin‐Heng Chiou, Ari D. Brettman, Lauren Daly, David C. Corney, Samuel Cheshier, Linda D. Shortliffe, Xiwei Wu, M Snyder, Pak H. Chan, Rona G. Giffard, Howard Y. Chang, Katrin Andreasson, Calvin J. Kuo - Nature Medicine 2017 cited by 260

  4. Mitochondrial and apoptotic neuronal death signaling pathways in cerebral ischemia

    Authors: Kuniyasu Niizuma, Hideyuki Yoshioka, Hailan Chen, Gab Seok Kim, Joo Eun Jung, Masataka Katsu, Nobuya Okami, Pak H. Chan - Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2009 cited by 358

  5. NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

    Authors: Angela Brennan, Sang Won Suh, Seok Joon Won, Purnima Narasimhan, Tiina M. Kauppinen, Hokyou Lee, Ylva Edling, Pak H. Chan, Raymond A. Swanson - Nature Neuroscience 2009 cited by 536

  6. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

    Authors: Yibing Li, Ting‐Ting Huang, Elaine J. Carlson, Simon Melov, Philip C. Ursell, Jean L. Olson, Linda J. Noble‐Haeusslein, Midori P. Yoshimura, Christoph N. Berger, Pak H. Chan, Douglas C. Wallace, Charles J. Epstein - Nature Genetics 1995 cited by 1,778

  7. Temporal Profile of Angiogenesis and Expression of Related Genes in the Brain After Ischemia

    Authors: Takeshi Hayashi, Nobuo Noshita, Taku Sugawara, Pak H. Chan - Journal of Cerebral Blood Flow & Metabolism 2003 cited by 392

  8. Reactive Oxygen Radicals in Signaling and Damage in the Ischemic Brain

    Authors: Pak H. Chan - Journal of Cerebral Blood Flow & Metabolism 2001 cited by 1,577

  9. A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

    Authors: Juha Yrjänheikki, Tiina Tikka, Riitta Keinänen, Gundars Goldsteins, Pak H. Chan, Jari Koıstınaho - National Academy of Sciences, Proceedings of the National Academy of Sciences 1999 cited by 1,034

  10. Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase

    Authors: Sang Won Suh, Elizabeth T. Gum, Aaron M. Hamby, Pak H. Chan, Raymond A. Swanson - Journal of Clinical Investigation 2007 cited by 418

  11. Free Radical Pathways in CNS Injury

    Authors: Anders Lewén, Paul G. Matz, Pak H. Chan - Journal of Neurotrauma 2000 cited by 761

  12. Matrix Metalloproteinase Inhibition Prevents Oxidative Stress-Associated Blood–Brain Barrier Disruption after Transient Focal Cerebral Ischemia

    Authors: Yvan Gasche, Jean-Christophe Copin, Taku Sugawara, Miki Fujimura, Pak H. Chan - Journal of Cerebral Blood Flow & Metabolism 2001 cited by 393

  13. Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemia

    Authors: Jeffrey M. Gidday, Yvan Gasche, J. C. Copin, Aarti R. Shah, Ronald S. Perez, Steven D. Shapiro, Pak H. Chan, T. S. Park - American Journal of Physiology-Heart and Circulatory Physiology 2005 cited by 473

  14. Book Review: Role of Superoxide Dismutases in Oxidative Damage and Neurodegenerative Disorders

    Authors: Carolina M. Maier, Pak H. Chan - The Neuroscientist 2002 cited by 326

  15. Hemoglobin-Induced Oxidative Stress Contributes to Matrix Metalloproteinase Activation and Blood–Brain Barrier Dysfunction in vivo

    Authors: Masataka Katsu, Kuniyasu Niizuma, Hideyuki Yoshioka, Nobuya Okami, Hiroyuki Sakata, Pak H. Chan - Journal of Cerebral Blood Flow & Metabolism 2010 cited by 149

  16. Astrocytes protect neurons from nitric oxide toxicity by a glutathione‐dependent mechanism

    Authors: Yongmei Chen, Nina Vartiainen, Weihai Ying, Pak H. Chan, Jari Koıstınaho, Raymond A. Swanson - Journal of Neurochemistry 2001 cited by 254

  17. Influence of Hyperglycemia on Oxidative Stress and Matrix Metalloproteinase-9 Activation After Focal Cerebral Ischemia/Reperfusion in Rats

    Authors: Hiroshi Kamada, Fengshan Yu, Chikako Nito, Pak H. Chan - Stroke 2007 cited by 309

  18. Reperfusion and Neurovascular Dysfunction in Stroke: from Basic Mechanisms to Potential Strategies for Neuroprotection

    Authors: Joo Eun Jung, Gab Seok Kim, Hailan Chen, Carolina M. Maier, Purnima Narasimhan, Yun Seon Song, Kuniyasu Niizuma, Masataka Katsu, Nobuya Okami, Hideyuki Yoshioka, Hiroyuki Sakata, Christina E. Goeders, Pak H. Chan - Molecular Neurobiology 2010 cited by 257

  19. Mitochondria and Neuronal Death/Survival Signaling Pathways in Cerebral Ischemia

    Authors: Pak H. Chan - Neurochemical Research 2004 cited by 298

  20. Inhibition of NADPH Oxidase is Neuroprotective after Ischemia—Reperfusion

    Authors: Hai Chen, Yun Seon Song, Pak H. Chan - Journal of Cerebral Blood Flow & Metabolism 2009 cited by 283

  21. VEGF Stimulates the ERK 1/2 Signaling Pathway and Apoptosis in Cerebral Endothelial Cells After Ischemic Conditions

    Authors: Purnima Narasimhan, Jing Liu, Yun Seon Song, Justin Massengale, Pak H. Chan - Stroke 2009 cited by 173

  22. Role of Oxidants in Ischemic Brain Damage

    Authors: Pak H. Chan - Stroke 1996 cited by 1,039

  23. Activation of the Akt/GSK3β Signaling Pathway Mediates Survival of Vulnerable Hippocampal Neurons after Transient Global Cerebral Ischemia in Rats

    Authors: Hidenori Endo, Chikako Nito, Hiroshi Kamada, Tatsuro Nishi, Pak H. Chan - Journal of Cerebral Blood Flow & Metabolism 2006 cited by 193

  24. Oxidative stress and mitochondrial dysfunction as determinants of ischemic neuronal death and survival

    Authors: Kuniyasu Niizuma, Hidenori Endo, Pak H. Chan - Journal of Neurochemistry 2009 cited by 381