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Steven D. Shapiro

Active 1982–2024

141
Papers
33,208
Citations
100
h-index
140
i10-index

Citations

Citations per year for Steven D. Shapiro1987: 1 citations1988: 2 citations1989: 1 citations1991: 2 citations1992: 27 citations1993: 23 citations1994: 43 citations1995: 32 citations1996: 76 citations1997: 89 citations1998: 173 citations1999: 223 citations2000: 342 citations2001: 332 citations2002: 400 citations2003: 502 citations2004: 505 citations2005: 614 citations2006: 563 citations2007: 546 citations2008: 465 citations2009: 483 citations2010: 387 citations2011: 407 citations2012: 326 citations2013: 311 citations2014: 312 citations2015: 293 citations2016: 235 citations2017: 281 citations2018: 231 citations2019: 668 citations2020: 603 citations2021: 622 citations2022: 497 citations2023: 375 citations2024: 531 citations2025: 234 citations2026: 4 citations1990: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 4,293 citing papers, 34.2% of this breakdownChina: 1,045 citing papers, 8.3% of this breakdownUnited Kingdom: 905 citing papers, 7.2% of this breakdownGermany: 683 citing papers, 5.4% of this breakdownCanada: 578 citing papers, 4.6% of this breakdownJapan: 549 citing papers, 4.4% of this breakdownFrance: 448 citing papers, 3.6% of this breakdownItaly: 372 citing papers, 3% of this breakdownNetherlands: 329 citing papers, 2.6% of this breakdownAustralia: 328 citing papers, 2.6% of this breakdownSpain: 307 citing papers, 2.5% of this breakdownBelgium: 268 citing papers, 2.1% of this breakdown
0%34.2%Other 19.5%

Institutions

Fields

  • Medicine47.4%
  • Biochemistry, Genetics and Molecular Biology35.9%
  • Immunology and Microbiology10.5%
  • Neuroscience1.9%
  • Health Professions0.8%
  • Engineering0.6%
  • Other2.9%

Topics

  • Protease and Inhibitor Mechanisms7.5%
  • Chronic Obstructive Pulmonary Disease (COPD) Research3.3%
  • Peptidase Inhibition and Analysis3.1%
  • Cell Adhesion Molecules Research2.8%
  • Blood Coagulation and Thrombosis Mechanisms2.2%
  • Immune cells in cancer2.2%
  • Other78.9%

Coauthors

All papers

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  1. Neutrophil elastase–mediated degradation of IRS-1 accelerates lung tumor growth

    Authors: A. McGarry Houghton, Danuta M. Rzymkiewicz, Hongbin Ji, Alyssa D. Gregory, Eduardo Egea, Heather Metz, Donna B. Stolz, Stephanie R. Land, Luiz A Marconcini, Corrine R. Kliment, Kimberly M. Jenkins, Keith A Beaulieu, Majd Mouded, Stuart J. Frank, Kwok‐Kin Wong, Steven D. Shapiro - Nature Medicine 2010 cited by 735

  2. Dysregulation of TGF-β1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice

    Authors: Xiangchun Wang, Shinya Inoué, Jianguo Gu, Eiji Miyoshi, Katsuhisa Noda, Wenzhe Li, Yoko Mizuno-Horikawa, Miyako Nakano, Michio Asahi, Motoko Takahashi, Naofumi Uozumi, Shinji Ihara, Seung Ho Lee, Yoshitaka Ikeda, Yukihiro Yamaguchi, Yoshiya Aze, Yoshiaki Tomiyama, Junichi Fujii, Keiichiro Suzuki, Akihiro Kondo, Steven D. Shapiro, Carlos López-Otı́n, Tomoyuki Kuwaki, Masaru Okabe, Koichi Honke, Naoyuki Taniguchi - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 cited by 491

  3. Extracellular Release of Mitochondrial DNA: Triggered by Cigarette Smoke and Detected in COPD

    Authors: Luca Giordano, Alyssa D. Gregory, Mireia Pérez-Verdaguer, Sarah A. Ware, Hayley Harvey, Evan DeVallance, Tomasz Brzóska, Prithu Sundd, Yingze Zhang, Frank C. Sciurba, Steven D. Shapiro, Brett A. Kaufman - Cells 2022 cited by 67

  4. Matrix Metalloproteinase MMP-12 Promotes Macrophage Transmigration Across Intestinal Epithelial Tight Junctions and Increases Severity of Experimental Colitis

    Authors: Meghali Nighot, Ashwinkumar Subramenium Ganapathy, Kushal Saha, Eric Suchanec, Eliseo F. Castillo, Alyssa D. Gregory, Steven D. Shapiro, Thomas Ma, Prashant K. Nighot - Journal of Crohn s and Colitis 2021 cited by 89

  5. Peripheral Blood Mononuclear Cell Gene Expression Profiles Predict Poor Outcome in Idiopathic Pulmonary Fibrosis

    Authors: Jose D. Herazo‐Maya, Imre Noth, Steven R. Duncan, Sung Hwan Kim, Shwu‐Fan Ma, George C. Tseng, Eleanor Feingold, Brenda Juan-Guardela, Thomas J. Richards, Yves A. Lussier, Yong Huang, Rekha Vij, Kathleen O. Lindell, Jianmin Xue, Kevin F. Gibson, Steven D. Shapiro, Joe G. N. Garcia, Naftali Kaminski - Science Translational Medicine 2013 cited by 350

  6. MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

    Authors: Thiennu H. Vu, J. Michael Shipley, Gabriele Bergers, Joel E. Berger, Jill A. Helms, Douglas Hanahan, Steven D. Shapiro, Robert M. Senior, Zena Werb - Cell 1998 cited by 1,764

  7. Requirement for Macrophage Elastase for Cigarette Smoke-Induced Emphysema in Mice

    Authors: R. Dean Hautamaki, Dale K. Kobayashi, Robert M. Senior, Steven D. Shapiro - Science 1997 cited by 1,472

  8. Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1

    Authors: Lygia V. Pereira, Sui Ying Lee, Barbara Gayraud-Morel, Kostantinos Andrikopoulos, Steven D. Shapiro, Tracie E. Bunton, Nancy Jensen Biery, Harry C. Dietz, Lynn Y. Sakai, Francesco Ramirez - National Academy of Sciences, Proceedings of the National Academy of Sciences 1999 cited by 549

  9. Neutrophil elastase targets virulence factors of enterobacteria

    Authors: Yvette Weinrauch, Doreen Drujan, Steven D. Shapiro, Jerrold Weiss, Arturo Zychlinsky - Nature 2002 cited by 335

  10. K-ras activation generates an inflammatory response in lung tumors

    Authors: H Ji, A. McGarry Houghton, Thomas J. Mariani, Samanthi A. Perera, C. B. Kim, Robert F. Padera, Giovanni Tonon, Kate McNamara, Luiz A Marconcini, Aram F. Hezel, Nabeel El-Bardeesy, Roderick T. Bronson, David J. Sugarbaker, Richard S. Maser, Steven D. Shapiro, Kwok‐Kin Wong - Oncogene 2005 cited by 267

  11. HIPPO–Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension

    Authors: Tatiana V. Kudryashova, Dmitry A. Goncharov, Andressa Peña, Neil J. Kelly, Rebecca Vanderpool, Jeff Baust, Ahasanul Kobir, William J. Shufesky, Ana L. Mora, Adrián E. Morelli, Jing Zhao, Kaori Ihida‐Stansbury, Baojun Chang, Horace M. DeLisser, Rubin M. Tuder, Steven M. Kawut, Herman H.W. Silljé, Steven D. Shapiro, Yutong Zhao, Elena A. Goncharova - American Journal of Respiratory and Critical Care Medicine 2016 cited by 147

  12. Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

    Authors: Robert Pyo, Jason K. Lee, J. Michael Shipley, John A. Curci, Dongli Mao, Scott J. Ziporin, Terri L. Ennis, Steven D. Shapiro, Robert M. Senior, Robert W. Thompson - Journal of Clinical Investigation 2000 cited by 827

  13. Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis

    Authors: Abderrazzaq Belaaouaj, Ronald McCarthy, Mary Baumann, Zhimin Gao, Timothy J. Ley, Soman N. Abraham, Steven D. Shapiro - Nature Medicine 1998 cited by 705

  14. Neutrophil Elastase Contributes to Cigarette Smoke-Induced Emphysema in Mice

    Authors: Steven D. Shapiro, Nir M. Goldstein, A. McGarry Houghton, Dale K. Kobayashi, Diane G. Kelley, Abderazzaq Belaaouaj - American Journal Of Pathology 2003 cited by 509

  15. Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemia

    Authors: Jeffrey M. Gidday, Yvan Gasche, J. C. Copin, Aarti R. Shah, Ronald S. Perez, Steven D. Shapiro, Pak H. Chan, T. S. Park - American Journal of Physiology-Heart and Circulatory Physiology 2005 cited by 473

  16. MMP12, Lung Function, and COPD in High-Risk Populations

    Authors: Gary M. Hunninghake, Michael H. Cho, Yohannes Tesfaigzi, Manuel E. Soto-Quirós, Lydiana Ávila, Jessica Lasky‐Su, Chris A. Stidley, Erik Melén, Cilla Söderhäll, Jenny Hallberg, Inger Kull, Juha Kere, Magnus Svartengren, Göran Pershagen, Magnus Wickman, Christoph Lange, Dawn L. DeMeo, Craig P. Hersh, Barbara J. Klanderman, Benjamin A. Raby, David Sparrow, Steven D. Shapiro, Edwin K. Silverman, Augusto A. Litonjua, Scott T. Weiss, Juan C. Celedón - New England Journal of Medicine 2009 cited by 375

  17. Matrix metalloproteinase degradation of extracellular matrix: biological consequences

    Authors: Steven D. Shapiro - Current Opinion in Cell Biology 1998 cited by 719

  18. Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice.

    Authors: J. Michael Shipley, Robin L. Wesselschmidt, Dale K. Kobayashi, Timothy J. Ley, Steven D. Shapiro - National Academy of Sciences, Proceedings of the National Academy of Sciences 1996 cited by 501

  19. Loss of integrin αvβ6-mediated TGF-β activation causes Mmp12-dependent emphysema

    Authors: David G. Morris, Xiaozhu Huang, Naftali Kaminski, Yanli Wang, Steven D. Shapiro, Gregory Dolganov, Adam B. Glick, Dean Sheppard - Nature 2003 cited by 498

  20. Lung transplantation for idiopathic pulmonary fibrosis enriches for individuals with telomere-mediated disease

    Authors: Jonathan K. Alder, Rachel M. Sutton, Carlo J. Iasella, Mehdi Nouraie, Ritchie Koshy, S. Hannan, Ernest G. Chan, Xiaoping Chen, Yingze Zhang, Mark J. Brown, Iulia Popescu, Melinda Veatch, Melissa Saul, Annerose Berndt, Barbara A. Methé, Alison Morris, Joseph M. Pilewski, Pablo G. Sánchez, Matthew R. Morrell, Steven D. Shapiro, Kathleen O. Lindell, Kevin F. Gibson, Daniel J. Kass, John F. McDyer - The Journal of Heart and Lung Transplantation 2021 cited by 48

  21. A randomized, controlled trial of protocol-directed versus physician-directed weaning from mechanical ventilation

    Authors: Marin H. Kollef, Steven D. Shapiro, Patricia Silver, Robert John, Donna Prentice, Sharon Sauer, Tom S. Ahrens, William D. Shannon, Darnetta Baker-Clinkscale - Critical Care Medicine 1997 cited by 840

  22. Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP

    Authors: Farideh Sabeh, Ichiro Ota, Kenn Holmbeck, Henning Birkedal‐Hansen, Paul D. Soloway, Milagros Balbı́n, Carlos López-Otı́n, Steven D. Shapiro, Masaki Inada, Stephen M. Krane, Edward Allen, Duane A. Chung, Stephen J. Weiss - The Journal of Cell Biology 2004 cited by 579

  23. Increased inflammation delays wound healing in mice deficient in collagenase‐2 (MMP‐8)

    Authors: Ana Gutiérrez‐Fernández, Masaki Inada, Milagros Balbı́n, Antonio Fueyo, Ana S. Pitiot, Aurora Astudillo, Kenji Hirose, Michiko Hirata, Steven D. Shapiro, Agnès Noël, Zena Werb, Stephen M. Krane, Carlos López-Otı́n, Xosé S. Puente - The FASEB Journal 2007 cited by 280

  24. Human Antibody Domains and Fragments Targeting Neutrophil Elastase as Candidate Therapeutics for Cancer and Inflammation-Related Diseases

    Authors: Xiaojie Chu, Zehua Sun, Du-San Baek, Wei Li, John W. Mellors, Steven D. Shapiro, Dimiter S. Dimitrov - International Journal of Molecular Sciences 2021 cited by 22