Patrick R. Griffin
Active 1976–2025
- 141
- Papers
- 30,301
- Citations
- 87
- h-index
- 138
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology43.6%
- Medicine26.6%
- Neuroscience9.9%
- Immunology and Microbiology4.5%
- Chemistry4.2%
- Agricultural and Biological Sciences2.7%
- Other8.5%
Topics
- Adipose Tissue and Metabolism3.6%
- Cell death mechanisms and regulation2.7%
- Receptor Mechanisms and Signaling2.7%
- Regulation of Appetite and Obesity2.1%
- Peroxisome Proliferator-Activated Receptors1.7%
- Neuropeptides and Animal Physiology1.5%
- Other85.7%
Coauthors
- Theodore M. Kamenecka24
- Michael J. Chalmers21
- Bruce D. Pascal20
- Scott J. Novick18
- Thomas P. Burris15
- Timothy S. Strutzenberg14
- Douglas J. Kojetin13
- Jie Zheng12
- Scott A. Busby12
- Venkatasubramanian Dharmarajan11
- Naresh Kumar10
- Rubén D. Garcia-Ordoñez10
- David Marciano9
- Laura A. Solt9
- Tudor Hughes8
- Devrishi Goswami7
- John B. Bruning7
- Mi Ra Chang7
- Bruce M. Spiegelman6
- Graham M. West6
- Jinsai Shang6
- Raymond C. Stevens6
- Valentine V. Courouble6
- Yongjun Wang6
All papers
- Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Authors: Hyeonwoo Kim, Christiane D. Wrann, Mark P. Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman - Cell 2018 cited by 632
- Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
Authors: Glenn R. Masson, John E. Burke, Natalie G. Ahn, Ganesh S. Anand, Christoph H. Borchers, Sébastien Brier, George M. Bou-Assaf, John R. Engen, S. Walter Englander, Johan H. Faber, Rachel A. Garlish, Patrick R. Griffin, Michael L. Gross, Miklós Guttman, Yoshitomo Hamuro, Albert J. R. Heck, Damian J. Houde, Roxana E. Iacob, Thomas J. D. Jørgensen, Igor A. Kaltashov, Judith P. Klinman, Lars Konermann, Petr Man, Leland Mayne, Bruce D. Pascal, Dana Reichmann, Mark Skehel, Joost Snijder, Timothy S. Strutzenberg, Eric S. Underbakke, Cornelia Wagner, Thomas E. Wales, Benjamin T. Walters, David D. Weis, Derek J. Wilson, Patrick L. Wintrode, Zhongqi Zhang, Jie Zheng, David C. Schriemer, Kasper D. Rand - Nature Methods 2019 cited by 769
- HP1 reshapes nucleosome core to promote phase separation of heterochromatin
Authors: Serena Sanulli, Michael J. Trnka, Venkatasubramanian Dharmarajan, Ryan W. Tibble, Bruce D. Pascal, Alma L. Burlingame, Patrick R. Griffin, John D. Gross, Geeta J. Narlikar - Nature 2019 cited by 542
- Molecular glue CELMoD compounds are regulators of cereblon conformation
Authors: Edmond R. Watson, Scott J. Novick, Mary E. Matyskiela, Philip P. Chamberlain, Andres H. de la Peña, J. Zhu, Eileen Tran, Patrick R. Griffin, Ingrid E. Wertz, Gabriel C. Lander - Science 2022 cited by 197
- Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d
Authors: Cheng Zhang, Silvana Konermann, Nicholas J. Brideau, Peter Lotfy, Xuebing Wu, Scott J. Novick, Timothy S. Strutzenberg, Patrick R. Griffin, Patrick D. Hsu, Dmitry Lyumkis - Cell 2018 cited by 295
- Structural and mechanistic bases for a potent HIV-1 capsid inhibitor
Authors: S.M. Bester, Guochao Wei, Haiyan Zhao, Daniel Adu‐Ampratwum, Naseer Iqbal, Valentine V. Courouble, Ashwanth C. Francis, Arun S. Annamalai, Parmit K. Singh, Nikoloz Shkriabai, Peter Van Blerkom, James H. Morrison, Eric M. Poeschla, Alan Engelman, Gregory B. Melikyan, Patrick R. Griffin, James R. Fuchs, Francisco J. Asturias, Mamuka Kvaratskhelia - Science 2020 cited by 240
- Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5
Authors: Jang Hyun Choi, Alexander S. Banks, Jennifer L. Estall, Shingo Kajimura, Pontus Boström, Dina Laznik, Jorge L. Ruas, Michael J. Chalmers, Theodore M. Kamenecka, Matthias Blüher, Patrick R. Griffin, Bruce M. Spiegelman - Nature 2010 cited by 887
- Structure of an AMPK complex in an inactive, ATP-bound state
Authors: Yan Yan, Somnath Mukherjee, Kaleeckal G. Harikumar, Timothy S. Strutzenberg, X. Edward Zhou, Kelly Suino-Powell, Ting-Hai Xu, Ryan D. Sheldon, Jared Lamp, J.S. Brunzelle, Katarzyna Radziwon, Abigail E. Ellis, Scott J. Novick, Irving E. Vega, Russell G. Jones, Laurence J. Miller, H. Eric Xu, Patrick R. Griffin, Anthony A. Kossiakoff, Karsten Melcher - Science 2021 cited by 121
- Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors
Authors: X. Edward Zhou, Yuanzheng He, Parker W. de Waal, Xiang Gao, Yanyong Kang, Ned Van Eps, Yanting Yin, Kuntal Pal, Devrishi Goswami, Thomas A. White, Anton Barty, Naomi R. Latorraca, Henry N. Chapman, Wayne L. Hubbell, Ron O. Dror, Raymond C. Stevens, Vadim Cherezov, Vsevolod V. Gurevich, Patrick R. Griffin, Oliver P. Ernst, Karsten Melcher, H. Eric Xu - Cell 2017 cited by 466
- Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
Authors: Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry, John P. Vaillancourt, Connie K. Ding, Michel Gallant, Yves Gareau, Patrick R. Griffin, Marc Labelle, Yuri Lazebnik, Neil A. Munday, Sayyaparaju M. Raju, Mark E. Smulson, Ting-Ting Yamin, Violeta Yu, Douglas K. Miller - Nature 1995 cited by 4,022
- Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Authors: Yanyong Kang, X. Edward Zhou, Xiang Gao, Yuanzheng He, Wei Liu, Andrii Ishchenko, Anton Barty, Thomas A. White, Oleksandr Yefanov, Gye Won Han, Qingping Xu, Parker W. de Waal, Jiyuan Ke, Minjia Tan, Chenghai Zhang, Arne Moeller, Graham M. West, Bruce D. Pascal, Ned Van Eps, Lydia N. Caro, Sergey A. Vishnivetskiy, Regina J. Lee, Kelly Suino-Powell, Xin Gu, Kuntal Pal, Jinming Ma, Xiaoyong Zhi, Sébastien Boutet, Garth J. Williams, M. Messerschmidt, Cornelius Gati, Nadia A. Zatsepin, Dingjie Wang, Daniel James, Shibom Basu, Shatabdi Roy-Chowdhury, Chelsie E. Conrad, Jesse Coe, Haiguang Liu, Stella Lisova, Christopher Kupitz, Ingo Grotjohann, Raimund Fromme, Yi Jiang, Minjia Tan, Huaiyu Yang, Jun Li, Meitian Wang, Zhong Zheng, Dianfan Li, Nicole Howe, Yingming Zhao, Jörg Standfuss, Kay Diederichs, Yuhui Dong, Clinton S. Potter, Bridget Carragher, Martin Caffrey, Hualiang Jiang, Henry N. Chapman, John C. H. Spence, Petra Fromme, Uwe Weierstall, Oliver P. Ernst, Vsevolod Katritch, Vsevolod V. Gurevich, Patrick R. Griffin, Wayne L. Hubbell, Raymond C. Stevens, Vadim Cherezov, Karsten Melcher, H. Eric Xu - Nature 2015 cited by 837
- Molecular Mimicry Regulates ABA Signaling by SnRK2 Kinases and PP2C Phosphatases
Authors: Fen-Fen Soon, Ley-Moy Ng, Xiaofeng Zhou, Graham M. West, Amanda Kovach, Michelle H. Tan, Kelly Suino-Powell, Yuanzheng He, Yong Xu, Michael J. Chalmers, J.S. Brunzelle, Huiming Zhang, Huaiyu Yang, Hualiang Jiang, Jun Li, Eu‐Leong Yong, Sean R. Cutler, Jian‐Kang Zhu, Patrick R. Griffin, Karsten Melcher, H. Eric Xu - Science 2011 cited by 598
- Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation
Authors: Sean W. Fanning, Christopher G. Mayne, Venkatasubramanian Dharmarajan, Kathryn E. Carlson, Teresa A. Martin, Scott J. Novick, Weiyi Toy, Bradley Green, Srinivas Panchamukhi, Benita S. Katzenellenbogen, Emad Tajkhorshid, Patrick R. Griffin, Yang Shen, Sarat Chandarlapaty, John A. Katzenellenbogen, Geoffrey L. Greene - eLife 2016 cited by 307
- Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes
Authors: Kfir Sharabi, Hua Lin, Clint D.J. Tavares, John E. Dominy, João Paulo Camporez, Rachel J. Perry, Roger Schilling, Amy K. Rines, Jaemin Lee, Marc Hickey, Melissa Bennion, Michelle Palmer, Partha P. Nag, Joshua A. Bittker, José R. Perez, Mark P. Jedrychowski, Umut Özcan, Steve P. Gygi, Theodore M. Kamenecka, Gerald I. Shulman, Stuart L. Schreiber, Patrick R. Griffin, Pere Puigserver - Cell 2017 cited by 213
- Glucocorticoid Receptor Function Regulated by Coordinated Action of the Hsp90 and Hsp70 Chaperone Cycles
Authors: Elaine Kirschke, Devrishi Goswami, Daniel R. Southworth, Patrick R. Griffin, David A. Agard - Cell 2014 cited by 422
- A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release
Authors: Andrew D. Howard, Scott D. Feighner, Doris Cully, Joseph P. Arena, Paul Liberator, Charles Rosenblum, Michel Hamelin, Donna L. Hreniuk, Oksana Palyha, Jennifer Anderson, Philip S. Paress, Carmen Dı́az, Michael F. Chou, Ken K. Liu, Karen K. McKee, Sheng‐Shung Pong, L Y Chaung, Alex Elbrecht, Mike Dashkevicz, R.P. Heavens, Mike Rigby, D.J.S. Sirinathsinghji, Dennis Dean, David G. Melillo, Arthur A. Patchett, Ravi P. Nargund, Patrick R. Griffin, Julie A. DeMartino, Sunil Gupta, James M. Schaeffer, Roy G. Smith, Lex H.T. Van der Ploeg - Science 1996 cited by 2,078
- Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation
Authors: Jang Hyun Choi, Alexander S. Banks, Theodore M. Kamenecka, Scott A. Busby, Michael J. Chalmers, Naresh Kumar, Dana S. Kuruvilla, Youseung Shin, Yuanjun He, John B. Bruning, David Marciano, Michael D. Cameron, Dina Laznik, Michael J. Jurczak, Stephan C. Schürer, D. Vidović, Gerald I. Shulman, Bruce M. Spiegelman, Patrick R. Griffin - Nature 2011 cited by 538
- Partial Agonists Activate PPARγ Using a Helix 12 Independent Mechanism
Authors: John B. Bruning, Michael J. Chalmers, Swati Prasad, Scott A. Busby, Theodore M. Kamenecka, Yuanjun He, K.W. Nettles, Patrick R. Griffin - Structure 2007 cited by 387
- Assessment and Teaching of 21st Century Skills
Authors: Patrick R. Griffin, Esther Care, Barry McGaw - 2011 cited by 998
- Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand
Authors: Laura A. Solt, Naresh Kumar, Philippe Nuhant, Yongjun Wang, Janelle Lauer, Jin Liu, Monica A. Istrate, Theodore M. Kamenecka, William Roush, D. Vidović, Stephan C. Schürer, Jihong Xu, Gail Wagoner, Paul D. Drew, Patrick R. Griffin, Thomas P. Burris - Nature 2011 cited by 505
- Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection
Authors: Guochao Wei, Naseer Iqbal, Valentine V. Courouble, Ashwanth C. Francis, Parmit K. Singh, Arpa Hudait, Arun S. Annamalai, S.M. Bester, Szu‐Wei Huang, Nikoloz Shkriabai, Lorenzo Briganti, Reed Haney, Vineet N. KewalRamani, Gregory A. Voth, Alan Engelman, Gregory B. Melikyan, Patrick R. Griffin, Francisco J. Asturias, Mamuka Kvaratskhelia - Nature Communications 2022 cited by 59
- Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling
Authors: Feng Zhang, Jian Yao, Jiyuan Ke, Li Zhang, Quang Vinh Lam, Xiu‐Fang Xin, X. Edward Zhou, Jian Chen, J.S. Brunzelle, Patrick R. Griffin, Mingguo Zhou, H. Eric Xu, Karsten Melcher, Sheng Yang He - Nature 2015 cited by 347
- Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α
Authors: Mu A, Thomas E. Wales, Haixia Zhou, Sorin-Valeriu Draga-Coletă, Christoph Gorgulla, Katherine Blackmore, Melanie J. Mittenbühler, Caroline R. Kim, Dina Bogoslavski, Qiuyang Zhang, Zifu Wang, Mark P. Jedrychowski, Hyuk‐Soo Seo, Kijun Song, Andrew Z. Xu, Luke Sebastian, Steven P. Gygi, Haribabu Arthanari, Sirano Dhe‐Paganon, Patrick R. Griffin, John R. Engen, Bruce M. Spiegelman - Molecular Cell 2023 cited by 63
- Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex
Authors: Dipak N. Patil, Shikha Singh, Thibaut Laboute, Timothy S. Strutzenberg, Xingyu Qiu, Di Wu, Scott J. Novick, Carol V. Robinson, Patrick R. Griffin, J.F. Hunt, Tina Izard, Appu K. Singh, Kirill A. Martemyanov - Science 2022 cited by 61
