Paul Dent
Active 1990–2024
- 160
- Papers
- 23,965
- Citations
- 97
- h-index
- 158
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology51%
- Medicine39.5%
- Immunology and Microbiology2.8%
- Neuroscience1.4%
- Computer Science1.2%
- Agricultural and Biological Sciences0.8%
- Other3.3%
Topics
- Protein Kinase Regulation and GTPase Signaling3.6%
- Melanoma and MAPK Pathways2.8%
- Cell death mechanisms and regulation2.8%
- Autophagy in Disease and Therapy2.7%
- Drug Transport and Resistance Mechanisms2.5%
- PI3K/AKT/mTOR signaling in cancer2%
- Other83.6%
Coauthors
- Steven Grant64
- Paul B. Fisher41
- Adly Yacoub29
- Mohamed Rahmani27
- Devanand Sarkar26
- Kristoffer Valerie23
- Clint Mitchell17
- Irina V. Lebedeva17
- Laurence Booth16
- Rupert Schmidt‐Ullrich14
- Yun Dai14
- Andrew Poklepovic13
- David T. Curiel13
- Moira Sauane12
- Thomas W. Sturgill12
- Zao-zhong Su12
- Rahul V. Gopalkrishnan11
- Ross B. Mikkelsen11
- Sarah Spiegel11
- Joseph N. Contessa10
- Margaret A. Park10
- Dean B. Reardon9
- Jane L. Roberts9
- Luni Emdad9
All papers
- Bile acids as regulatory molecules
Authors: Phillip B. Hylemon, Huiping Zhou, William M. Pandak, Shunlin Ren, Gregorio Gil, Paul Dent - Journal of Lipid Research 2009 cited by 693
- Conjugated Bile Acids Activate the Sphingosine–1–Phosphate Receptor 2 in Primary Rodent Hepatocytes
Authors: Elaine Studer, Xiqiao Zhou, Renping Zhao, Yun Wang, Kazuaki Takabe, Masayuki Nagahashi, William M. Pandak, Paul Dent, Sarah Spiegel, Ruihua Shi, Weiren Xu, Xuyuan Liu, Pat Bohdan, Luyong Zhang, Huiping Zhou, Phillip B. Hylemon - Hepatology 2011 cited by 316
- Targeting the Bcl-2 family for cancer therapy
Authors: Shibu Thomas, Bridget A. Quinn, Swadesh K. Das, Rupesh Dash, Luni Emdad, Santanu Dasgupta, Xiang‐Yang Wang, Paul Dent, John C. Reed, Maurizio Pellecchia, Devanand Sarkar, Paul B. Fisher - Expert Opinion on Therapeutic Targets 2012 cited by 267
- Autophagy
Authors: Sujit K. Bhutia, Subhadip Mukhopadhyay, Niharika Sinha, Durgesh Nandini Das, Prashanta Kumar Panda, Samir Kumar Patra, Tapas K. Maiti, Mahitosh Mandal, Paul Dent, Xiangyang Wang, Swadesh K. Das, Devanand Sarkar, Paul B. Fisher - Advances in cancer research 2013 cited by 221
- Mitochondrial Localized Stat3 Promotes Breast Cancer Growth via Phosphorylation of Serine 727
Authors: Qifang Zhang, Vidisha Raje, Vasily A. Yakovlev, Adly Yacoub, Karol Szczepanek, Jeremy A. Meier, Marta Derecka, Qun Chen, Ying Hu, Jennifer D. Sisler, Hossein A. Hamed, Edward J. Lesnefsky, Kristoffer Valerie, Paul Dent, Andrew C. Larner - Journal of Biological Chemistry 2013 cited by 182
- The role of cell signaling in the crosstalk between autophagy and apoptosis in the regulation of tumor cell survival in response to sorafenib and neratinib
Authors: Laurence Booth, Jane L. Roberts, Paul Dent - Seminars in Cancer Biology 2019 cited by 83
- MAPK pathways in radiation responses
Authors: Paul Dent, Adly Yacoub, Paul B. Fisher, Michael P. Hagan, Steven Grant - Oncogene 2003 cited by 603
- The role of cell signalling in the crosstalk between autophagy and apoptosis
Authors: Laurence Booth, Seyedmehrad Tavallai, Hossein A. Hamed, Nichola Cruickshanks, Paul Dent - Cellular Signalling 2013 cited by 341
- HDAC inhibitors enhance the immunotherapy response of melanoma cells
Authors: Laurence Booth, Jane L. Roberts, Andrew Poklepovic, John M. Kirkwood, Paul Dent - Oncotarget 2017 cited by 136
- The Kinase Inhibitor Sorafenib Induces Cell Death through a Process Involving Induction of Endoplasmic Reticulum Stress
Authors: Mohamed Rahmani, Eric Maynard Davis, Timothy Ryan Crabtree, Joseph Habibi, Tri K. Nguyen, Paul Dent, Steven Grant - Molecular and Cellular Biology 2007 cited by 250
- Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction
Authors: Anindita Das, David Durrant, Clint Mitchell, Eric K. Mayton, Nicholas N Hoke, Fadi N. Salloum, Margaret A. Park, Ian Qureshi, Ray Lee, Paul Dent, Rakesh C. Kukreja - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 161
- (Curcumin+sildenafil) enhances the efficacy of 5FU and anti‐PD1 therapies in vivo
Authors: Paul Dent, Laurence Booth, Jane L. Roberts, Andrew Poklepovic, John F. Hancock - Journal of Cellular Physiology 2020 cited by 44
- Radiation-induced cell signaling: inside-out and outside-in
Authors: Kristoffer Valerie, Adly Yacoub, Michael P. Hagan, David T. Curiel, Paul B. Fisher, Steven Grant, Paul Dent - Molecular Cancer Therapeutics 2007 cited by 327
- Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells
Authors: Paul Dent, Laurence Booth, Jane L. Roberts, Junchen Liu, Andrew Poklepovic, Alshad S. Lalani, David A. Tuveson, Jennifer Martinez, John F. Hancock - Oncogene 2019 cited by 85
- Eradication of Therapy-resistant Human Prostate Tumors Using an Ultrasound-guided Site-specific Cancer Terminator Virus Delivery Approach
Authors: Adelaide Greco, Altomare Di Benedetto, Candace M. Howard, Sarah Kelly, Rounak Nande, Yulia Dementieva, Michele Miranda, Arturo Brunetti, Marco Salvatore, Luigi Claudio, Devanand Sarkar, Paul Dent, David T. Curiel, Paul B. Fisher, Pier Paolo Claudio - Molecular Therapy 2009 cited by 81
- Investigational CHK1 inhibitors in early phase clinical trials for the treatment of cancer
Authors: Paul Dent - Expert Opinion on Investigational Drugs 2019 cited by 59
- Alteration of Ceramide Synthase 6/C16-Ceramide Induces Activating Transcription Factor 6-mediated Endoplasmic Reticulum (ER) Stress and Apoptosis via Perturbation of Cellular Ca2+ and ER/Golgi Membrane Network
Authors: Can E. Senkal, Suriyan Ponnusamy, Yefim Manevich, Marisa Meyers‐Needham, Sahar A. Saddoughi, Archana Mukhopadyay, Paul Dent, Jacek Bielawski, Besim Öğretmen - Journal of Biological Chemistry 2011 cited by 135
- Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes
Authors: Youwen Fang, Song Iy Han, Clint Mitchell, Seema Gupta, Elaine Studer, Steven Grant, Phillip B. Hylemon, Paul Dent - Hepatology 2004 cited by 130
- Crosstalk between ERK, AKT, and cell survival
Authors: Paul Dent - Cancer Biology & Therapy 2014 cited by 97
- Deoxycholic Acid (DCA) Causes Ligand-independent Activation of Epidermal Growth Factor Receptor (EGFR) and FAS Receptor in Primary Hepatocytes: Inhibition of EGFR/Mitogen-activated Protein Kinase-Signaling Module Enhances DCA-induced Apoptosis
Authors: Liang Qiao, Elaine Studer, Kevin Leach, Robert McKinstry, Seema Gupta, Roy H. Decker, Rakesh C. Kukreja, Kristoffer Valerie, Prakash Nagarkatti, Wafik S. El‐Deiry, Jeffery D. Molkentin, Rupert Schmidt‐Ullrich, Paul B. Fisher, Steven Grant, Philip B. Hylemon, Paul Dent - Molecular Biology of the Cell 2001 cited by 233
- Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes
Authors: Liang Qiao, Adly Yacoub, Elaine Studer, Seema Gupta, Xin Pei, Steven Grant, Philip B. Hylemon, Paul Dent - Hepatology 2002 cited by 144
- Autocrine regulation of mda -7/IL-24 mediates cancer-specific apoptosis
Authors: Moira Sauane, Zao-zhong Su, Pankaj Gupta, Irina V. Lebedeva, Paul Dent, Devanand Sarkar, Paul B. Fisher - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 121
- Phase I Study of Sorafenib and Vorinostat in Advanced Hepatocellular Carcinoma
Authors: Sarah Gordon, William P. McGuire, Danielle Shafer, Richard K. Sterling, Hannah M. Lee, Scott Matherly, John D. Roberts, Prithviraj Bose, Mary Beth Tombes, E. Ellen Shrader, Alison A. Ryan, Maciej Kmieciak, Tri Nguyen, Xiaoyan Deng, Dipankar Bandyopadhyay, Paul Dent, Andrew Poklepovic - American Journal of Clinical Oncology 2019 cited by 41
- Mutations in the Phosphatidylinositol-3-Kinase Pathway Predict for Antitumor Activity of the Inhibitor PX-866 whereas Oncogenic Ras Is a Dominant Predictor for Resistance
Authors: Nathan T. Ihle, Robert Lemos, Peter Wipf, Adly Yacoub, Clint Mitchell, Doris R. Siwak, Gordon B. Mills, Paul Dent, D. Lynn Kirkpatrick, Garth Powis - Cancer Research 2008 cited by 274
