Peter C. Isakson
Active 1975–2005
- 61
- Papers
- 20,231
- Citations
- 61
- h-index
- 61
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine62.2%
- Biochemistry, Genetics and Molecular Biology11.8%
- Neuroscience5.8%
- Immunology and Microbiology5.7%
- Chemistry4.4%
- Pharmacology, Toxicology and Pharmaceutics3.1%
- Other7%
Topics
- Inflammatory mediators and NSAID effects15.1%
- Estrogen and related hormone effects4%
- Eicosanoids and Hypertension Pharmacology3.8%
- Synthesis and biological activity2.8%
- Computational Drug Discovery Methods2.1%
- Neuroinflammation and Neurodegeneration Mechanisms1.4%
- Other70.8%
Coauthors
- Karen Seibert20
- Jaime L. Masferrer12
- Carol M. Koboldt10
- Scott D. Hauser8
- Yan Zhang8
- Philip Needleman7
- Gilbert Geis6
- Amy W. Veenhuizen5
- Bryan L. Spangelo5
- James K. Gierse5
- K. Leahy5
- Richard C. Hubbard5
- Robert M. MacLeod5
- Susan A. Gregory5
- Alex Shaffer4
- Ben S. Zweifel4
- E S Vitetta4
- Ellen Puré4
- Kenneth M. Verburg4
- Paul W. Collins4
- William E. Perkins4
- Allan M. Judd3
- Gary D. Anderson3
- Ish Khanna3
All papers
- Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
Authors: Ravi G. Kurumbail, Anna M. Stevens, James K. Gierse, Joseph J. McDonald, Roderick A. Stegeman, Jina Y. Pak, Daniel Gildehaus, Julie M. iyashiro, Thomas D. Penning, Karen Seibert, Peter C. Isakson, William C. Stallings - Nature 1996 cited by 1,914
- Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)
Authors: Thomas D. Penning, John J. Talley, Stephen R. Bertenshaw, Jeffery S. Carter, Paul W. Collins, Stephen Docter, Matthew J. Graneto, Len F. Lee, James W. Malecha, Julie M. Miyashiro, Roland S. Rogers, D. Joseph Rogier, Stella S. Yu, Gary D. Anderson, Earl G. Burton, J. Nita Cogburn, Susan A. Gregory, Carol M. Koboldt, William E. Perkins, Karen Seibert, Amy W. Veenhuizen, Yan Y. Zhang, Peter C. Isakson - Journal of Medicinal Chemistry 1997 cited by 1,960
- Pharmacological analysis of cyclooxygenase-1 in inflammation
Authors: Chris Smith, Yan Zhang, Carol M. Koboldt, Jerry Muhammad, Ben S. Zweifel, Alex Shaffer, John J. Talley, Jaime L. Masferrer, Karen Seibert, Peter C. Isakson - National Academy of Sciences, Proceedings of the National Academy of Sciences 1998 cited by 811
- Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis.
Authors: Graham Anderson, Scott D. Hauser, Kelly L. McGarity, Magdalena Bremer, Peter C. Isakson, S A Gregory - Journal of Clinical Investigation 1996 cited by 572
- Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain.
Authors: Karen Seibert, Y Zhang, K. Leahy, Scott D. Hauser, Jaime L. Masferrer, W Perkins, L Lee, Peter C. Isakson - National Academy of Sciences, Proceedings of the National Academy of Sciences 1994 cited by 1,562
- Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic.
Authors: Jaime L. Masferrer, Ben S. Zweifel, Pamela T. Manning, Scott D. Hauser, K. Leahy, Walter G. Smith, Peter C. Isakson, Karen Seibert - National Academy of Sciences, Proceedings of the National Academy of Sciences 1994 cited by 1,315
- Anti-inflammatory and Upper Gastrointestinal Effects of Celecoxib in Rheumatoid Arthritis
Authors: Lee S. Simon, Arthur L. Weaver, David Y. Graham, Alan Kivitz, Peter E. Lipsky, Richard C. Hubbard, Peter C. Isakson, Kenneth M. Verburg, Shawn Yu, William W. Zhao, Gilbert Geis - JAMA 1999 cited by 804
- Celecoxib versus diclofenac in long-term management of rheumatoid arthritis: randomised double-blind comparison
Authors: Paul Emery, H. Zeidler, Tore K Kvien, Mario Guslandi, R. Naudin, Helen Stead, Kenneth M. Verburg, Peter C. Isakson, Richard C. Hubbard, Gilbert Geis - The Lancet 1999 cited by 540
- Effects of Celecoxib, a Novel Cyclooxygenase‐2 Inhibitor, on Platelet Function in Healthy Adults: A Randomized, Controlled Trial
Authors: Philip T. Leese, Richard C. Hubbard, Aziz Karim, Peter C. Isakson, Shawn Yu, Gilbert Geis - The Journal of Clinical Pharmacology 2000 cited by 374
- Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo.
Authors: Joseph P. Portanova, Y Zhang, Graham Anderson, Scott D. Hauser, Jaime L. Masferrer, Karen Seibert, S A Gregory, Peter C. Isakson - The Journal of Experimental Medicine 1996 cited by 420
- 1,2-Diarylcyclopentenes as Selective Cyclooxygenase-2 Inhibitors and Orally Active Anti-inflammatory Agents
Authors: James J. Li, Gary D. Anderson, Earl G. Burton, J. Nita Cogburn, Joe Collins, Danny J. Garland, Susan A. Gregory, H. T. Huang, Peter C. Isakson - Journal of Medicinal Chemistry 1995 cited by 177
- Leukocytes synthesize angiotensinogen.
Authors: R. Ariel Gómez, Laura L. Norling, N. Wilfong, Peter C. Isakson, Kevin R. Lynch, Randy A. Hock, P. J. Quesenberry - Hypertension 1993 cited by 93
- Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2.
Authors: Hongmiao Sheng, Jian‐Hua Shao, Susan C. Kirkland, Peter C. Isakson, Robert J. Coffey, Jason D. Morrow, R. Daniel Beauchamp, Raymond N. DuBois - Journal of Clinical Investigation 1997 cited by 722
- T cell-derived B cell differentiation factor(s). Effect on the isotype switch of murine B cells.
Authors: Peter C. Isakson, Ellen Puré, E S Vitetta, Peter H. Krammer - The Journal of Experimental Medicine 1982 cited by 447
- Treatment of Osteoarthritis With Celecoxib, a Cyclooxygenase-2 Inhibitor: A Randomized Controlled Trial
Authors: W. Bensen, Justus J. Fiechtner, James I. McMillen, William W. Zhao, Shawn Yu, Emmett M. Woods, Richard C. Hubbard, Peter C. Isakson, Kenneth M. Verburg, Gilbert Geis - Mayo Clinic Proceedings 1999 cited by 351
- Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia
Authors: Masaki Nakayama, Koichi Uchimura, Raymond L. Zhu, Tetsuya Nagayama, Marie E. Rose, R. Anne Stetler, Peter C. Isakson, Jun Chen, Steven H. Graham - National Academy of Sciences, Proceedings of the National Academy of Sciences 1998 cited by 345
- INTERLEUKIN-6 STIMULATES ANTERIOR PITUITARY HORMONE RELEASEIN VITRO.
Authors: Bryan L. Spangelo, Allan M. Judd, Peter C. Isakson, Robert M. MacLeod - Endocrinology 1989 cited by 323
- Cyclooxygenases and the Central Nervous System
Authors: Walter E. Kaufmann, Katrin I. Andreasson, Peter C. Isakson, Paul F. Worley - Prostaglandins 1997 cited by 283
- Kinetic basis for selective inhibition of cyclo-oxygenases
Authors: James K. Gierse, Carol M. Koboldt, Mark C. Walker, Karen Seibert, Peter C. Isakson - Biochemical Journal 1999 cited by 279
- 1,2-Diarylpyrroles as Potent and Selective Inhibitors of Cyclooxygenase-2
Authors: Ish Khanna, Richard M. Weier, Yi Yu, Paul W. Collins, Julie M. Miyashiro, Carol M. Koboldt, Amy W. Veenhuizen, J L Currie, Karen Seibert, Peter C. Isakson - Journal of Medicinal Chemistry 1997 cited by 169
- 1,2-Diarylimidazoles as Potent, Cyclooxygenase-2 Selective, and Orally Active Antiinflammatory Agents
Authors: Ish Khanna, Richard M. Weier, Yi Yu, Xiang D. Xu, Francis J. Koszyk, Paul W. Collins, Carol M. Koboldt, Amy W. Veenhuizen, William E. Perkins, J J Casler, Jaime L. Masferrer, Yan Y. Zhang, Susan A. Gregory, Karen Seibert, Peter C. Isakson - Journal of Medicinal Chemistry 1997 cited by 153
- Molecular cloning and expression of human leukotriene-C4 synthase.
Authors: D. Welsch, David Creely, Scott D. Hauser, Karl J. Mathis, Gwen G. Krivi, Peter C. Isakson - National Academy of Sciences, Proceedings of the National Academy of Sciences 1994 cited by 143
- Cyclooxygenase-2 In Human Pathological Disease
Authors: Alane Koki, Nasir Khan, B. Mark Woerner, Andrew J. Dannenberg, Lisa Olson, Karen Seibert, Dorothy Edwards, M.M. Hardy, Peter C. Isakson, Jaime L. Masferrer - Advances in experimental medicine and biology 2002 cited by 133
- Valdecoxib: Assessment of Cyclooxygenase-2 Potency and Selectivity
Authors: James K. Gierse, Yan Zhang, William F. Hood, Mark C. Walker, Jennifer S. Trigg, Timothy J. Maziasz, Carol M. Koboldt, Jerry Muhammad, Ben S. Zweifel, Jaime L. Masferrer, Peter C. Isakson, Karen Seibert - Journal of Pharmacology and Experimental Therapeutics 2005 cited by 79
